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Contrast enhanced breast imaging

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https://www.readbyqxmd.com/read/29663411/breast-cancer-mri-radiomics-an-overview-of-algorithmic-features-and-impact-of-inter-reader-variability-in-annotating-tumors
#1
Ashirbani Saha, Michael R Harowicz, Maciej A Mazurowski
PURPOSE: To review features used in MRI radiomics of breast cancer and study the inter-reader stability of the features METHODS: We implemented 529 algorithmic features that can be extracted from tumor and fibroglandular tissue (FGT) in breast MRIs. The features were identified based on a review of the existing literature with consideration of their usage, prognostic ability, and uniqueness. The set was then extended so that it comprehensively describes breast cancer imaging characteristics...
April 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29659398/mixed-epithelial-and-stromal-tumor-of-the-kidney-mimicking-malignancy-on-18f-fdg-pet-ct-in-a-patient-with-breast-cancer
#2
Chongjiao Li, Yueli Tian, Meijuan Shen, Bing Wen, Yong He
Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare renal tumor composed of solid and cystic components. Mixed epithelial and stromal tumor of the kidney has no pathognomonic imaging feature. It is difficult to distinguish MESTK from other cystic renal neoplasms using current radiological methods. We report a rare case of MESTK that was diagnosed in a 46-year-old woman with breast cancer. F-FDG PET/CT and contrast-enhanced CT features of MESTK are presented, which could potentially provide useful information in the differential diagnoses of cystic renal neoplasms...
April 13, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29651715/can-tumor-coverage-evaluated-24-h-post-radiofrequency-ablation-predict-local-tumor-progression-of-liver-metastases
#3
Frederik Vandenbroucke, Jef Vandemeulebroucke, Nico Buls, Ruedi F Thoeni, Johan de Mey
PURPOSE: To assess the predictive value for local tumor progression (LTP) of geometrical tumor coverage using the contrast-enhanced (ce-)CT images acquired before and within 24 h after radiofrequency (RF) ablation. METHODS: Twenty patients (6 male and 14 female, median age 62 years) with 45 focal hypovascular liver metastases (16 colorectal carcinoma, 3 melanoma and 1 breast carcinoma) underwent RF ablation under CT-guidance and received a ce-PET/CT scan within 24 h post-procedure...
April 12, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29650780/differentiating-atypical-hemangiomas-and-metastatic-vertebral-lesions-the-role-of-t1-weighted-dynamic-contrast-enhanced-mri
#4
K A Morales, J Arevalo-Perez, K K Peck, A I Holodny, E Lis, S Karimi
BACKGROUND AND PURPOSE: Vertebral hemangiomas are benign vascular lesions that are almost always incidentally found in the spine. Their classic typical hyperintense appearance on T1- and T2-weighted MR images is diagnostic. Unfortunately, not all hemangiomas have the typical appearance, and they can mimic metastases on routine MR imaging. These are generally referred to as atypical hemangiomas and can result in misdiagnosis and ultimately additional imaging, biopsy, and unnecessary costs...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29650314/a-topo-graph-model-for-indistinct-target-boundary-definition-from-anatomical-images
#5
Hui Cui, Xiuying Wang, Jianlong Zhou, Guanzhong Gong, Stefan Eberl, Yong Yin, Lisheng Wang, Dagan Feng, Michael Fulham
BACKGROUND AND OBJECTIVE: It can be challenging to delineate the target object in anatomical imaging when the object boundaries are difficult to discern due to the low contrast or overlapping intensity distributions from adjacent tissues. METHODS: We propose a topo-graph model to address this issue. The first step is to extract a topographic representation that reflects multiple levels of topographic information in an input image. We then define two types of node connections - nesting branches (NBs) and geodesic edges (GEs)...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29649747/polymeric-micelles-theranostic-co-delivery-system-for-poorly-water-soluble-drugs-and-contrast-agents
#6
Jaydev R Upponi, Kaushal Jerajani, Dattatri K Nagesha, Praveen Kulkarni, Srinivas Sridhar, Craig Ferris, Vladimir P Torchilin
Interest in theranostic agents has continued to grow because of their promise for simultaneous cancer detection and therapy. A platform-based nanosized combination agent suitable for the enhanced diagnosis and treatment of cancer was prepared using polymeric polyethylene glycol-phosphatidylethanolamine-based micelles loaded with both, poorly soluble chemotherapeutic agent paclitaxel and hydrophobic superparamagnetic iron oxide nanoparticles (SPION), a Magnetic Resonance Imaging contrast agent. The co-loaded paclitaxel and SPION did not affect each other's functional properties in vitro...
March 31, 2018: Biomaterials
https://www.readbyqxmd.com/read/29649266/preoperative-dynamic-breast-magnetic-resonance-imaging-kinetic-features-using-computer-aided-diagnosis-association-with-survival-outcome-and-tumor-aggressiveness-in-patients-with-invasive-breast-cancer
#7
Sang Yu Nam, Eun Sook Ko, Yaeji Lim, Boo-Kyung Han, Eun Young Ko, Ji Soo Choi, Jeong Eon Lee
OBJECTIVES: To evaluate whether preoperative breast dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging kinetic features, assessed using computer-aided diagnosis (CAD), can predict survival outcome and tumor aggressiveness in patients with invasive breast cancer. MATERIALS AND METHODS: Between March and December 2011, 301 women who underwent preoperative DCE MR imaging for invasive breast cancer, with CAD data, were identified. All MR images were retrospectively evaluated using a commercially available CAD system...
2018: PloS One
https://www.readbyqxmd.com/read/29644993/apparent-diffusion-coefficient-to-subdivide-breast-imaging-reporting-and-data-system-magnetic-resonance-imaging-bi-rads-mri-category-4-lesions
#8
Dandan Liu, Zhaogui Ba, Xiaoli Ni, Linhong Wang, Dexin Yu, Xiangxing Ma
BACKGROUND This study aims to subdivide BI-RADS-MRI (Breast Imaging Reporting and Data System Magnetic Resonance Imaging) Category 4 lesions and to evaluate the role of Fischer's scoring system, apparent diffusion coefficient (ADC), and Fischer's + ADC in differential diagnosis of breast lesions. MATERIAL AND METHODS This study retrospectively analyzed the data of 143 patients (150 breast lesions), who were diagnosed by biopsy, and received dynamic contrast enhancement and diffusion-weighted imaging. The diagnostic efficacies of ADC, Fischer's scoring system, and the Fischer's + ADC were analyzed by the receiver operating characteristics curve...
April 12, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29622130/comparison-of-contrast-enhanced-mammography-and-contrast-enhanced-breast-mr-imaging
#9
REVIEW
John Lewin
Contrast-enhanced mammography (CEM) is a contrast-enhanced modality for breast cancer detection that utilizes iodinated contrast and dual-energy imaging performed on a digital mammography unit with only slight modifications. It is approved by the US Food and Drug Administration, commercially available, and in routine clinical use at centers around the world. It has similar sensitivity and specificity to MR Imaging and has advantages in terms of cost, patient acceptability, and examination time. MR Imaging has some advantages compared with CEM, especially in its ability to image the complete axilla and the chest wall...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29620604/diffusion-weighted-imaging-with-apparent-diffusion-coefficient-mapping-for-breast-cancer-detection-as-a-stand-alone-parameter-comparison-with-dynamic-contrast-enhanced-and-multiparametric-magnetic-resonance-imaging
#10
Katja Pinker, Linda Moy, Elizabeth J Sutton, Ritse M Mann, Michael Weber, Sunitha B Thakur, Maxine S Jochelson, Zsuzsanna Bago-Horvath, Elizabeth A Morris, Pascal At Baltzer, Thomas H Helbich
PURPOSE: The aims of this study were to compare dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) with apparent diffusion coefficient mapping as a stand-alone parameter without any other supportive sequence for breast cancer detection and to assess its combination as multiparametric MRI (mpMRI) of the breast. MATERIALS AND METHODS: In this institutional review board-approved single-center study, prospectively acquired data of 106 patients who underwent breast MRI from 12/2010 to 09/2014 for an imaging abnormality (Breast Imaging Reporting and Data System 0, 4/5) were retrospectively analyzed...
April 3, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29620140/diagnostic-and-prognostic-values-of-contrast%C3%A2-enhanced-ultrasound-combined-with-diffusion%C3%A2-weighted-magnetic-resonance-imaging-in-different-subtypes-of-breast-cancer
#11
Gui-Feng Liu, Zong-Qiang Wang, Shu-Hua Zhang, Xue-Feng Li, Lin Liu, Ying-Ying Miao, Shao-Nan Yu
The present study aimed to investigate the diagnostic and prognostic values of contrast‑enhanced ultrasound (CEUS) combined with diffusion‑weighted magnetic resonance imaging (DW‑MRI) in different subtypes of breast cancer (BC). CEUS and DW‑MRI were conducted in 232 patients with BC prior to surgical treatment. Patients were categorized as having the luminal A subtype, the luminal B subtype, triple‑negative subtype or the human epidermal growth factor receptor 2 (Her‑2)‑positive subtype according to their expression of the estrogen receptor (ER), progesterone receptor (PR) and Her‑2, as detected by immunohistochemistry...
March 27, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29616496/how-to-use-the-kaiser-score-as-a-clinical-decision-rule-for-diagnosis-in-multiparametric-breast-mri-a-pictorial-essay
#12
REVIEW
Matthias Dietzel, Pascal A T Baltzer
Due to its superior sensitivity, breast MRI (bMRI) has been established as an important additional diagnostic tool in the breast clinic and is used for screening in patients with an elevated risk for breast cancer. Breast MRI, however, is a complex tool, providing multiple images containing several contrasts. Thus, reading bMRI requires a structured approach. A lack of structure will increase the rate of false-positive findings and sacrifice most of the advantages of bMRI as additional work-up will be required...
April 3, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29613991/imaging-findings-in-papillary-breast-lesions-an-analysis-of-ductal-findings-on-magnetic-resonance-imaging-and-ultrasound
#13
Ozgur Sarica, Murat Dokdok
PURPOSE: This study aims to analyze the imaging features of dilated ducts or ductal extension/relation of masses detected by ultrasound (US) and magnetic resonance imaging (MRI) and to correlate the results obtained through these 2 different imaging methods. Furthermore, the ability of the ductal relation pattern in differentiating benign and malignant lesions was explored. METHODS AND MATERIALS: Magnetic resonance imaging and US findings of 56 patients who had a pathologic diagnosis of papillary lesion were examined...
April 2, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29606871/ultrasound-molecular-imaging-of-breast-cancer-in-mcf-7-orthotopic-mice-using-gold-nanoshelled-poly-lactic-co-glycolic-acid-nanocapsules-a-novel-dual-targeted-ultrasound-contrast-agent
#14
Li Xu, Jing Du, Caifeng Wan, Yu Zhang, Shaowei Xie, Hongli Li, Hong Yang, Fenghua Li
Background: The development of nanoscale molecularly targeted ultrasound contrast agents (UCAs) with high affinity and specificity is critical for ultrasound molecular imaging in the early detection of breast cancer. Purpose: To prospectively evaluate ultrasound molecular imaging with dual-targeted gold nanoshelled poly(lactide-co-glycolic acid) nanocapsules carrying vascular endothelial growth factor receptor type 2 (VEGFR2) and p53 antibodies (DNCs) in MCF-7 orthotopic mice model...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29606631/workflow-considerations-for-incorporation-of-contrast-enhanced-spectral-mammography-into-a-breast-imaging-practice
#15
Jordana Phillips, Jennifer Steinkeler, Komal Talati, Alexander Brook, Vandana Dialani, Michael Fishman, Priscilla J Slanetz, Tejas S Mehta
No abstract text is available yet for this article.
March 30, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29594402/contrast-enhanced-cone-beam-breast-ct-cbbct-clinical-performance-compared-to-mammography-and-mri
#16
Susanne Wienbeck, Uwe Fischer, Susanne Luftner-Nagel, Joachim Lotz, Johannes Uhlig
OBJECTIVES: To evaluate the diagnostic accuracy of contrast-enhanced (CE) cone-beam breast computed tomography (CBBCT) in dense breast tissue and compare it to non-contrast (NC) CBBCT, mammography (MG) and magnetic resonance imaging (MRI). METHODS: This prospective institutional review board-approved study included 41 women (52 breasts) with American College of Radiology (ACR) density types c or d and Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 assessments in MG or ultrasound (US)...
March 28, 2018: European Radiology
https://www.readbyqxmd.com/read/29571172/management-of-high-risk-breast-lesions-found-on-mammogram-or-ultrasound-the-value-of-contrast-enhanced-mri-to-exclude-malignancy
#17
Jill A Hammersley, Savannah C Partridge, Grace C Blitzer, Sarah Deitch, Habib Rahbar
PURPOSE: To evaluate the performance of magnetic resonance imaging (MRI) to exclude malignancy in biopsy-proven high-risk breast lesions prior to surgical excision. MATERIAL AND METHODS: Breast MRIs performed after a core needle biopsy (CNB) yielding high-risk pathology were evaluated for the presence of suspicious enhancement. The diagnostic performance of MRI to exclude malignancy was calculated. RESULTS: The average reader sensitivity, specificity, negative predictive value, positive predictive value and accuracy of MRI were 92%, 51%, 98%, 22% and 56%, respectively...
March 13, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29570895/repeatability-reproducibility-and-accuracy-of-quantitative-mri-of-the-breast-in-the-community-radiology-setting
#18
Anna G Sorace, Chengyue Wu, Stephanie L Barnes, Angela M Jarrett, Sarah Avery, Debra Patt, Boone Goodgame, Jeffery J Luci, Hakmook Kang, Richard G Abramson, Thomas E Yankeelov, John Virostko
BACKGROUND: Quantitative diffusion-weighted MRI (DW-MRI) and dynamic contrast-enhanced MRI (DCE-MRI) have the potential to impact patient care by providing noninvasive biological information in breast cancer. PURPOSE/HYPOTHESIS: To quantify the repeatability, reproducibility, and accuracy of apparent diffusion coefficient (ADC) and T1 -mapping of the breast in community radiology practices. STUDY TYPE: Prospective. SUBJECTS/PHANTOM: Ice-water DW-MRI and T1 gel phantoms were used to assess accuracy...
March 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29560489/noninvasive-magnetic-resonance-photoacoustic-imaging-for-photothermal-therapy-response-monitoring
#19
Jing Ye, Guifeng Fu, Xiaohui Yan, Jingyi Liu, Xiaoyong Wang, Liang Cheng, Fan Zhang, Phillip Zhe Sun, Gang Liu
In vivo assessment of vascular permeability and therapeutic response provides novel insights into photothermal therapy (PTT) that is currently under clinical investigation. We have developed noninvasive imaging strategies to improve the monitoring of nanoparticle-mediated PTT responses for personalized nanomedicine. Briefly, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and photoacoustic imaging (PAI) were applied to study the enhanced permeability and retention (EPR) effect in tumor models of different microvascular permeabilities (i...
March 21, 2018: Nanoscale
https://www.readbyqxmd.com/read/29556347/2d-superparamagnetic-tantalum-carbide-composite-mxenes-for-efficient-breast-cancer-theranostics
#20
Zhuang Liu, Han Lin, Menglong Zhao, Chen Dai, Shengjian Zhang, Weijun Peng, Yu Chen
Background : The emergence of two-dimensional MXenes has spurred their versatile applications in broad fields, but the exploring of novel MXene-based family members and their potential applications in theranostic nanomedicine (concurrent diagnostic imaging and therapy) have been rarely explored. In this work, we report the construction of a novel superparamagnetic MXene-based theranostic nanoplatform for efficient breast-cancer theranostics, which was based on intriguing tantalum carbide (Ta4 C3 ) MXene and its further rational surface-superparamagnetic iron-oxide functionalization (Ta4 C3 -IONP-SPs composite MXenes) for efficient breast-cancer theranostic...
2018: Theranostics
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