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Digital breast tomosynthesis

Julie E Weiss, Martha Goodrich, Kimberly A Harris, Rachael E Chicoine, Marie B Synnestvedt, Steve J Pyle, Jane S Chen, Sally D Herschorn, Elisabeth F Beaber, Jennifer S Haas, Anna N A Tosteson, Tracy Onega
PURPOSE: To assess indication for examination for four breast imaging modalities and describe the complexity and heterogeneity of data sources and ascertainment methods. METHODS: Indication was evaluated among the Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) breast cancer research centers (PRCs). Indication data were reported overall and separately for four breast imaging modalities: digital mammography (DM), digital breast tomosynthesis (DBT), ultrasound (US), and magnetic resonance imaging (MRI)...
October 12, 2016: Journal of the American College of Radiology: JACR
James V Fiorica
This article is an overview of the modalities available for breast cancer screening. The modalities discussed include digital mammography, digital breast tomosynthesis, breast ultrasonography, magnetic resonance imaging, and clinical breast examination. There is a review of pertinent randomized controlled trials, studies and meta-analyses which contributed to the evolution of screening guidelines. Ultimately, 5 major medical organizations formulated the current screening guidelines in the United States. The lack of consensus in these guidelines represents an ongoing controversy about the optimal timing and method for breast cancer screening in women...
October 12, 2016: Clinical Obstetrics and Gynecology
P Whelehan, S H Heywang-Köbrunner, S J Vinnicombe, A Hacker, A Jänsch, A Hapca, R Gray, M Jenkin, K Lowry, R Oeppen, M Reilly, M Stahnke, A Evans
AIM: To compare the diagnostic accuracy of standard screening images plus single-view digital breast tomosynthesis (DBT), using Siemens DBT equipment, with standard screening images plus supplementary mammographic views in non-calcific, screen-detected mammographic abnormalities. MATERIALS AND METHODS: Participants were unselected women aged 50-69 years recalled within a population-based European breast screening programme for assessment of soft-tissue mammographic abnormalities...
October 10, 2016: Clinical Radiology
Katrina E Korhonen, Susan P Weinstein, Elizabeth S McDonald, Emily F Conant
Digital breast tomosynthesis (DBT) represents a valuable addition to breast cancer screening by decreasing recall rates while increasing cancer detection rates. The increased accuracy achieved with DBT is due to the quasi-three-dimensional format of the reconstructed images and the ability to "scroll through" breast tissue in the reconstructed images, thereby reducing the effect of tissue superimposition found with conventional planar digital mammography. The margins of both benign and malignant lesions are more conspicuous at DBT, which allows improved lesion characterization, increased reader confidence, and improved screening outcomes...
October 7, 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Nicole Berger, Sibylle Dubach Schwizer, Zsuzsanna Varga, Christoph Rageth, Thomas Frauenfelder, Andreas Boss
OBJECTIVES: The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG). MATERIAL AND METHODS: The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT...
September 13, 2016: Clinical Imaging
X Qian, X Tang
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
X Qian, X Tang
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Ravi K Samala, Heang-Ping Chan, Lubomir M Hadjiiski, Mark A Helvie
With IRB approval, digital breast tomosynthesis (DBT) images of human subjects were collected using a GE GEN2 DBT prototype system. Corresponding digital mammograms (DMs) of the same subjects were collected retrospectively from patient files. The data set contained a total of 237 views of DBT and equal number of DM views from 120 human subjects, each included 163 views with microcalcification clusters (MCs) and 74 views without MCs. The data set was separated into training and independent test sets. The pre-processing, object prescreening and segmentation, false positive reduction and clustering strategies for MC detection by three computer-aided detection (CADe) systems designed for DM, DBT, and a planar projection image generated from DBT were analyzed...
October 7, 2016: Physics in Medicine and Biology
David R Dance, Ioannis Sechopoulos
The estimation of the mean glandular dose to the breast (MGD) for x-ray based imaging modalities forms an essential part of quality control and is needed for risk estimation and for system design and optimisation. This review considers the development of methods for estimating the MGD for mammography, digital breast tomosynthesis (DBT) and dedicated breast CT (DBCT). Almost all of the methodology used employs Monte Carlo calculated conversion factors to relate the measurable quantity, generally the incident air kerma, to the MGD...
October 7, 2016: Physics in Medicine and Biology
Lauro Bucchi, Paolo Belli, Eva Benelli, Daniela Bernardi, Beniamino Brancato, Massimo Calabrese, Luca A Carbonaro, Francesca Caumo, Beatrice Cavallo-Marincola, Paola Clauser, Chiara Fedato, Alfonso Frigerio, Vania Galli, Livia Giordano, Paola Golinelli, Giovanna Mariscotti, Laura Martincich, Stefania Montemezzi, Doralba Morrone, Carlo Naldoni, Adriana Paduos, Pietro Panizza, Federica Pediconi, Fiammetta Querci, Antonio Rizzo, Gianni Saguatti, Alberto Tagliafico, Rubina M Trimboli, Chiara Zuiani, Francesco Sardanelli
Women who were previously treated for breast cancer (BC) are an important particular subgroup of women at intermediate BC risk. Their breast follow-up should be planned taking in consideration a 1.0-1.5 % annual rate of loco-regional recurrences and new ipsilateral or contralateral BCs during 15-20 years, and be based on a regional/district invitation system. This activity should be carried out by a Department of Radiology integrating screening and diagnostics in the context of a Breast Unit. We recommend the adoption of protocols dedicated to women previously treated for BC, with a clear definition of responsibilities, methods for invitation, site(s) of visits, methods for clinical and radiological evaluation, follow-up duration, role and function of family doctors and specialists...
September 6, 2016: La Radiologia Medica
M Funke
Advances in imaging of the female breast have substantially influenced the diagnosis and probably also the therapy and prognosis of breast cancer in the past few years. This article gives an overview of the most important imaging modalities in the diagnosis of breast cancer. Digital mammography is considered to be the gold standard for the early detection of breast cancer. Digital breast tomosynthesis can increase the diagnostic accuracy of mammography and is used for the assessment of equivocal or suspicious mammography findings...
October 2016: Der Radiologe
Tokiko Endo, Takako Morita, Mikinao Oiwa, Namiko Suda, Yasuyuki Sato, Shu Ichihara, Misaki Shiraiwa, Kazuaki Yoshikawa, Takao Horiba, Hirotoshi Ogawa, Yukie Hayashi, Tomonari Sendai, Takahisa Arai
BACKGROUND: The objectives of this study were: (1) to evaluate the detectability of full-field digital mammography (FFDM) plus dual-mode digital breast tomosynthesis (DBT) and compare it with that of FFDM alone and (2) to compare the detectability of high-resolution-mode (HR mode used with 40°-angle imaging, 100-µm pixel size, and higher dose) DBT with that of standard-mode (ST mode used with 15°-angle imaging, 150-µm pixel size, and lower dose) DBT for diagnostic evaluation. MATERIALS: The local Institutional Review Board approved this retrospective study of two different sets of cases...
September 1, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Johannes G Korporaal, Thomas Mertelmeier
No abstract text is available yet for this article.
September 2016: Radiology
Richard E Sharpe, Shambavi Venkataraman, Jordana Phillips, Vandana Dialani, Valerie J Fein-Zachary, Seema Prakash, Priscilla J Slanetz, Tejas S Mehta
No abstract text is available yet for this article.
September 2016: Radiology
Agostino Pozz, Angelo Della Corte, Mustapha A El Lakis, HeonJae Jeong
Digital breast tomosynthesis (DBT) as a breast cancer screening modality, through generation of three dimensional images during standard mammographic compression, can reduce interference from breast tissue overlap, increasing conspicuity of invasive cancers while concomitantly reducing falsepositive results. We here conducted a systematic review on previous studies to synthesize the evidence of DBT efficacy, eventually 18 articles being included in the analysis. The most commonly emerging topics were advantages of DBT screening tool in terms of recall rates, cancer detection rates and costeffectiveness, preventing unnecessary burdens on women and the healthcare system...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Samantha P Zuckerman, Emily F Conant, Brad M Keller, Andrew D A Maidment, Bruno Barufaldi, Susan P Weinstein, Marie Synnestvedt, Elizabeth S McDonald
Purpose To evaluate the early implementation of synthesized two-dimensional (s2D) mammography in a population screened entirely with s2D and digital breast tomosynthesis (DBT) (referred to as s2D/DBT) and compare recall rates and cancer detection rates to historic outcomes of digital mammography combined with DBT (referred to as digital mammography/DBT) screening. Materials and Methods This was an institutional review board-approved and HIPAA-compliant retrospective interpretation of prospectively acquired data with waiver of informed consent...
July 28, 2016: Radiology
Krithika Rangarajan, Smriti Hari, Sanjay Thulkar, Sanjay Sharma, Anurag Srivastava, Rajinder Parshad
CONTEXT: Mammography in dense breasts is challenging due to lesion obscuration by tissue overlap. Does tomosynthesis offers a solution? AIMS: To study the impact of digital breast tomosynthesis (DBT) in characterizing lesions in breasts of different mammographic densities. SETTINGS AND DESIGN: Prospective blinded study comparing mammography in two views with Mammography + Tomosynthesis. METHODS AND MATERIAL: Tomosynthesis was performed in 199 patients who were assigned Breast imaging reporting and data system (BIRADS) categories 0, 3, 4, or 5 on two-dimensional (2D) mammogram...
April 2016: Indian Journal of Radiology & Imaging
Giovanna Mariscotti, Paolo Belli, Daniela Bernardi, Beniamino Brancato, Massimo Calabrese, Luca A Carbonaro, Beatrice Cavallo-Marincola, Francesca Caumo, Paola Clauser, Laura Martinchich, Stefania Montemezzi, Pietro Panizza, Federica Pediconi, Alberto Tagliafico, Rubina M Trimboli, Chiara Zuiani, Francesco Sardanelli
Women who underwent chest radiation therapy (CRT) during pediatric/young-adult age (typically, lymphoma survivors) have an increased breast cancer risk, in particular for high doses. The cumulative incidence from 40 to 45 years of age is 13-20 %, similar to that of BRCA mutation carriers for whom contrast-enhanced magnetic resonance imaging (MRI) is recommended. However, in women who underwent CRT, MRI sensitivity is lower (63-80 %) and that of mammography higher (67-70 %) than those observed in women with hereditary predisposition, due to a higher incidence of ductal carcinoma in situ with microcalcifications and low neoangiogenesis...
July 12, 2016: La Radiologia Medica
Youichi Machida, Ai Saita, Hirofumi Namba, Eisuke Fukuma
BACKGROUND: A new software version of VolparaDensity (Volpara Algorithm version 1.5.1) is capable of calculating volumetric breast density (VBD) using either full-field digital mammography (FFDM) or digital breast tomosynthesis (DBT) images. In this preliminary study, we evaluated the feasibility and consistency of this new automated software. FINDINGS: Raw data from both DBT and FFDM were acquired from women breast cancer screening at our institution between April and August 2015 using...
2016: SpringerPlus
Daniela Bernardi, Petra Macaskill, Marco Pellegrini, Marvi Valentini, Carmine Fantò, Livio Ostillio, Paolina Tuttobene, Andrea Luparia, Nehmat Houssami
BACKGROUND: Breast tomosynthesis (pseudo-3D mammography) improves breast cancer detection when added to 2D mammography. In this study, we examined whether integrating 3D mammography with either standard 2D mammography acquisitions or with synthetic 2D images (reconstructed from 3D mammography) would detect more cases of breast cancer than 2D mammography alone, to potentially reduce the radiation burden from the combination of 2D plus 3D acquisitions. METHODS: The Screening with Tomosynthesis Or standard Mammography-2 (STORM-2) study was a prospective population-based screening study comparing integrated 3D mammography (dual-acquisition 2D-3D mammography or 2D synthetic-3D mammography) with 2D mammography alone...
August 2016: Lancet Oncology
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