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Digital breast tomosynthesis

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https://www.readbyqxmd.com/read/28436856/task-based-modeling-of-an-5k-ultra-high-resolution-medical-imaging-system-for-digital-breast-tomosynthesis
#1
Chumin Zhao, Jerzy Kanicki
High-resolution, low noise x-ray detectors based on CMOS active pixel sensor (APS) technology have demonstrated superior imaging performance for digital breast tomosynthesis (DBT). This paper presents a task-based model for a high resolution medical imaging system to evaluate its ability to detect simulated microcalcifications and masses as lesions for breast cancer. Three-dimensional (3D) cascaded system analysis for a 50 μm pixel pitch CMOS APS x-ray detector was integrated with an object task function, a medical imaging display model, and the human eye contrast sensitivity function to calculate the detectability index and area under the ROC curve (AUC)...
April 19, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28411676/synthesized-digital-mammography-imaging
#2
REVIEW
Phoebe E Freer, Nicole Winkler
Synthesized mammography (SM) is a new imaging technique similar to digital mammography constructed from an acquired digital breast tomosynthesis (DBT) examination. SM allows for widespread screening using DBT, maintaining the benefits of DBT while decreasing the radiation of DBT by nearly half. This article reviews studies evaluating SM, most of which suggest that SM may be appropriate to use clinically to replace an actual acquired conventional 2-dimensional full-field digital mammogram (FFDM) when using DBT for breast cancer screening...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28411675/breast-tomosynthesis-practical-considerations
#3
REVIEW
Sarah M Friedewald
Digital breast tomosynthesis (DBT) is rapidly becoming the new standard of care for breast cancer screening. DBT has improved on the limitations of traditional digital mammography by increasing cancer detection and decreasing false-positive examinations. Interpretation of DBT is slightly different than digital mammography and therefore experience with the technology is paramount to achieve best performance. Examples of malignancies that should be recalled and benign findings that are safely called as benign are provided in this article...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28411674/breast-tomosynthesis-clinical-evidence
#4
REVIEW
Steven Poplack
In the last 20 years, there has been rapid evolution of the clinical research on digital breast tomosynthesis supporting its adoption in clinical breast imaging practice. Beginning with proof of principle pilot observational studies and culminating in prospective population-based screening trials and outcome reporting from clinical practice, there is a wealth of data on the DBT technology. This article catalogs the scientific and clinical evidence of DBT, highlighting some of the most important studies that have been reported to date...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28398001/an-update-on-carbon-nanotube-enabled-x-ray-sources-for-biomedical-imaging
#5
REVIEW
Connor Puett, Christina Inscoe, Allison Hartman, Jabari Calliste, Dora K Franceschi, Jianping Lu, Otto Zhou, Yueh Z Lee
A new imaging technology has emerged that uses carbon nanotubes (CNT) as the electron emitter (cathode) for the X-ray tube. Since the performance of the CNT cathode is controlled by simple voltage manipulation, CNT-enabled X-ray sources are ideal for the repetitive imaging steps needed to capture three-dimensional information. As such, they have allowed the development of a gated micro-computed tomography (CT) scanner for small animal research as well as stationary tomosynthesis, an experimental technology for large field-of-view human imaging...
April 11, 2017: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/28391808/fully-automated-nipple-detection-in-digital-breast-tomosynthesis
#6
Seung-Hoon Chae, Ji-Wook Jeong, Jang-Hwan Choi, Eun Young Chae, Hak Hee Kim, Young-Wook Choi, Sooyeul Lee
BACKGROUND AND OBJECTIVE: We propose a nipple detection algorithm for use with digital breast tomosynthesis (DBT) images. DBT images have been developed to overcome the weaknesses of 2D mammograms for denser breasts by providing 3D breast images. The nipple location acts as an invaluable landmark in DBT images for aligning the right and left breasts and describing the relative location of any existing lesions. METHODS: Nipples may be visible or invisible in a breast image, and therefore a nipple detection method must be able to detect the nipples for both cases...
May 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28378409/diffusion-of-digital-breast-tomosynthesis-among-women-in-primary-care-associations-with-insurance-type
#7
Cheryl R Clark, Tor D Tosteson, Anna N A Tosteson, Tracy Onega, Julie E Weiss, Kimberly A Harris, Jennifer S Haas
Digital breast tomosynthesis (DBT) has shown potential to improve breast cancer screening and diagnosis compared to digital mammography (DM). The FDA approved DBT use in conjunction with conventional DM in 2011, but coverage was approved by CMS recently in 2015. Given changes in coverage policies, it is important to monitor diffusion of DBT by insurance type. This study examined DBT trends and estimated associations with insurance type. From June 2011 to September 2014, DBT use in 22 primary care centers in the Dartmouth -Brigham and Women's Hospital Population-based Research Optimizing Screening through Personalized Regimens research center (PROSPR) was examined among women aged 40-89...
April 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28377347/-influence-of-projection-data-correction-on-digital-breast-tomosynthesis-imaging
#8
Xin-Yu Zhang, Hua Zhang, Zhao-Ying Bian, Dong Zeng, Ji He, Xiu-Mei Tian, Jian-Hua Ma, Jing Huang
OBJECTIVE: To investigate the effect of detector performance during digital breast tomography (DBT) projection data acquisition on reconstructed image quality. METHODS: With reference to the traditional detector data correction method and the specific data acquisition pattern in DBT imaging, we utilized dark field correction, light field and its gain correction for processing the projection data collected by the detector. The reconstructed images were evaluated using iterative reconstruction method based on total generalized variation (TGV)...
March 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28376261/theoretical-investigation-of-the-noise-performance-of-active-pixel-imaging-arrays-based-on-polycrystalline-silicon-thin-film-transistors
#9
Martin Koniczek, Larry E Antonuk, Youcef El-Mohri, Albert K Liang, Qihua Zhao
PURPOSE: Active matrix flat-panel imagers, which typically incorporate a pixelated array with one a-Si:H thin-film transistor (TFT) per pixel, have become ubiquitous by virtue of many advantages, including large monolithic construction, radiation tolerance and high DQE. However, at low exposures such as those encountered in fluoroscopy, digital breast tomosynthesis and breast computed tomography, DQE is degraded due to the modest average signal generated per interacting x-ray relative to electronic additive noise levels of ~1000 e, or greater...
April 4, 2017: Medical Physics
https://www.readbyqxmd.com/read/28374502/the-role-of-digital-breast-tomosynthesis-in-the-breast-assessment-clinic-a-review
#10
REVIEW
Suneeta Mall, Sarah Lewis, Patrick Brennan, Jennie Noakes, Claudia Mello-Thoms
Mammography has long been considered as the primary technique in breast cancer detection and assessment. Despite low specificity, mammography has been preferred over other contemporary techniques such as magnetic resonance imaging (MRI), computed tomography (CT) and ultrasonography (US) due to superior sensitivity and significant health economic benefits. The development of a new technique, a limited angle cone beam pseudo-three-dimensional tomosynthesis, digital breast tomosynthesis (DBT), has gained momentum...
April 4, 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28368663/imaging-features-and-conspicuity-of-invasive-lobular-carcinomas-on-digital-breast-tomosynthesis
#11
Foucauld Chamming's, Ellen Kao, Ann Aldis, Romuald Ferré, Atilla Omeroglu, Caroline Reinhold, Benoit Mesurolle
OBJECTIVES: To review the imaging features of invasive lobular carcinoma (ILC) seen on Digital breast tomosynthesis (DBT) in comparison with invasive ductal carcinoma (IDC), and to evaluate whether DBT could improve conspicuity and tumor size assessment of ILC in comparison with digital mammography (DM). METHODS: Institutional review board with waiver of informed consent was obtained for this retrospective study. Patients with ILC or IDC who underwent DBT and DM at the time of diagnosis were included...
April 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28331239/evaluation-of-a-marker-clip-system-in-sonographically-guided-core-needle-biopsy-for-breast-cancer-localization-before-and-after-neoadjuvant-chemotherapy
#12
R Schulz-Wendtland, P Dankerl, M R Bani, P A Fasching, K Heusinger, M P Lux, S M Jud, C Rauh, C M Bayer, M G Schrauder, M W Beckmann, M Uder, B Brehm, C R Loehberg
Introduction The placement of intramammary marker clips has proven to be helpful for tumor localization in patients undergoing neoadjuvant chemotherapy and breast-conserving surgery. The purpose of our study was to investigate the feasibility of using a clip marker system for breast cancer localization and its influence on the imaging assessment of treatment responses after neoadjuvant chemotherapy. Patients and Methods Between March and June 2015, a total of 25 patients (n = 25), with a suspicion of invasive breast cancer with diameters of at least 2 cm (cT2), underwent preoperative sonographically guided core needle biopsy using a single-use breast biopsy system (HistoCore™) and intramammary clip marking using a directly adapted clip system based on the established O-Twist Marker™, before their scheduled preoperative neoadjuvant chemotherapy...
February 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28318506/assessment-of-disease-extent-on-contrast-enhanced-mri-in-breast-cancer-detected%C3%A2-at-digital-breast-tomosynthesis-versus%C3%A2-digital-mammography-alone
#13
A V Chudgar, E F Conant, S P Weinstein, B M Keller, M Synnestvedt, P Yamartino, E S McDonald
AIM: To compare the utility of breast magnetic resonance imaging (MRI) in determining the extent of disease in patients with newly diagnosed breast cancer detected on combination digital breast tomosynthesis (DBT) versus digital screening mammography (DM). MATERIALS AND METHODS: Review of 24,563 DBT-screened patients and 10,751 DM-screened patients was performed. Two hundred and thirty-five DBT patients underwent subsequent MRI examinations; 82 to determine extent of disease after newly diagnosed breast cancer...
March 16, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28303582/generation-and-analysis-of-clinically-relevant-breast-imaging-x-ray-spectra
#14
Andrew M Hernandez, J Anthony Seibert, Anita Nosratieh, John M Boone
PURPOSE: The purpose of this work was to develop and make available x-ray spectra for some of the most widely used digital mammography (DM), breast tomosynthesis (BT), and breast CT (bCT) systems in North America. METHODS: The Monte Carlo code MCNP6 was used to simulate minimally-filtered (only beryllium) x-ray spectra at 8 tube potentials from 20 to 49 kV for DM/BT, and 9 tube potentials from 35 to 70 kV for bCT. Vendor-specific anode compositions, effective anode angles, focal spot sizes, source-to-detector distances, and beryllium filtration were simulated...
March 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28298592/full-field-digital-mammography-and-digital-breast-tomosynthesis
#15
Marlene M Johnson
Innovation in breast imaging techniques is leading to better breast cancer detection. Concurrently, breast cancer screening recommendations are changing, and breast density is becoming a more significant factor in breast cancer screening. Digital mammography has become the preferred screening method, with more breast imaging centers including the use of digital breast tomosynthesis (DBT). The technology's role in breast imaging has not been clarified fully, and several clinical trials are addressing DBT. This article presents research findings on digital mammography and DBT and explores the future role of 3-D breast imaging...
January 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28291738/design-and-validation-of-realistic-breast-models-for-use-in-multiple-alternative-forced-choice-virtual-clinical-trials
#16
Premkumar Elangovan, Alistair Mackenzie, David R Dance, Kenneth C Young, Victoria Cooke, Louise Wilkinson, Rosalind M Given-Wilson, Matthew G Wallis, Kevin Wells
A novel method has been developed for generating quasi-realistic voxel phantoms which simulate the compressed breast in mammography and digital breast tomosynthesis (DBT). The models are suitable for use in virtual clinical trials requiring realistic anatomy which use the multiple alternative forced choice (AFC) paradigm and patches from the complete breast image. The breast models are produced by extracting features of breast tissue components from DBT clinical images including skin, adipose and fibro-glandular tissue, blood vessels and Cooper's ligaments...
April 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28287917/does-reader-performance-with-digital-breast-tomosynthesis-vary-according-to-experience-with-two-dimensional-mammography
#17
Lorraine Tucker, Fiona J Gilbert, Susan M Astley, Amanda Dibden, Archana Seth, Juliet Morel, Sara Bundred, Janet Litherland, Herman Klassen, Gerald Lip, Hema Purushothaman, Hilary M Dobson, Linda McClure, Philippa Skippage, Katherine Stoner, Caroline Kissin, Ursula Beetles, Yit Yoong Lim, Emma Hurley, Jane Goligher, Rumana Rahim, Tanja J Gagliardi, Tamara Suaris, Stephen W Duffy
Purpose To assess whether individual reader performance with digital breast tomosynthesis (DBT) and two-dimensional (2D) mammography varies with number of years of experience or volume of 2D mammograms read. Materials and Methods After written informed consent was obtained, 8869 women (age range, 29-85 years; mean age, 56 years) were recruited into the TOMMY trial (A Comparison of Tomosynthesis with Digital Mammography in the UK National Health Service Breast Screening Program), an ethically approved, multicenter, multireader, retrospective reading study, between July 2011 and March 2013...
May 2017: Radiology
https://www.readbyqxmd.com/read/28268510/simplified-computer-aided-detection-scheme-of-microcalcification-clusters-in-digital-breast-tomosynthesis-images
#18
Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee
A computer-aided detection (CADe) algorithm for clustered microcalcifications (MCs) in reconstructed digital breast tomosynthesis (DBT) images is suggested. The MC-like objects were enhanced by a Hessian-based 3D calcification response function, and a signal-to-noise ratio (SNR) enhanced image was also generated to screen the MC clustering seed objects. A connected component segmentation method was used to detect the cluster seed objects, which were considered as potential clustering centers of MCs. Bounding cubes for the accepted clustering seed candidate were generated and the overlapping cubes were combined and examined...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28252233/with-the-advent-of-tomosynthesis-in-the-workup-of-mammographic-abnormality-is-spot-compression-mammography-now-obsolete-an-initial-clinical-experience
#19
Neasa Ni Mhuircheartaigh, Louise Coffey, Hannah Fleming, Ann O' Doherty, Sorcha McNally
To determine if the routine use of spot compression mammography is now obsolete in the assessment of screen detected masses, asymmetries and architectural distortion since the availability of digital breast tomosynthesis. We introduced breast tomosynthesis in the workup of screen detected abnormalities in our screening center in January 2015. During an initial learning period with tomosynthesis standard spot compression views were also performed. Three consultant breast radiologists retrospectively reviewed all screening mammograms recalled for assessment over the first 6-month period...
March 2, 2017: Breast Journal
https://www.readbyqxmd.com/read/28226684/simplified-computer-aided-detection-scheme-of-microcalcification-clusters-in-digital-breast-tomosynthesis-images
#20
Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Sooyeul Lee, Ji-Wook Jeong, Hak Hee Kim, Eun Young Chae, Young Wook Choi, Seung-Hoon Chae
A computer-aided detection (CADe) algorithm for clustered microcalcifications (MCs) in reconstructed digital breast tomosynthesis (DBT) images is suggested. The MC-like objects were enhanced by a Hessian-based 3D calcification response function, and a signal-to-noise ratio (SNR) enhanced image was also generated to screen the MC clustering seed objects. A connected component segmentation method was used to detect the cluster seed objects, which were considered as potential clustering centers of MCs. Bounding cubes for the accepted clustering seed candidate were generated and the overlapping cubes were combined and examined...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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