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Digital breast tomosynthesis

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https://www.readbyqxmd.com/read/29328943/interval-breast-cancers-in-the-screening-with-tomosynthesis-or-standard-mammography-storm-population-based-trial
#1
Nehmat Houssami, Daniela Bernardi, Francesca Caumo, Silvia Brunelli, Carmine Fantò, Marvi Valentini, Giovanna Romanucci, Maria A Gentilini, Manuel Zorzi, Petra Macaskill
BACKGROUND & METHODS: The prospective 'screening with tomosynthesis or standard mammography' (STORM) trial recruited women participating in biennial breast screening in Italy (2011-2012), and compared sequential screen-readings based on 2D-mammography alone or based on tomosynthesis (integrated 2D/3D-mammography). The STORM trial showed that tomosynthesis screen-reading significantly increased breast cancer detection compared to 2D-mammography alone. The present study completes reporting of the trial by examining interval breast cancers ascertained at two year follow-up...
January 9, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29317038/role-of-digital-breast-tomosynthesis-in-screening-and-diagnostic-breast-imaging
#2
Stamatia Destounis
Digital breast tomosynthesis is quickly becoming the standard of care in breast cancer screening and diagnosis. Since its introduction to the clinical landscape in 2011, radiologists specializing in breast disease diagnosis around the country have made the decision to adopt the technology for both screening and diagnostic applications; with adoption growing substantially in present day. Users of the technology have attested to the benefits the technology affords, both in screening and the diagnostic evaluation of patients, through peer-reviewed publications and scientific presentations in recent years...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317035/deciphering-the-breast-density-inform-law-movement-implications-for-practice
#3
Sean D Raj, Valerie Fein-Zachary, Priscilla J Slanetz
Although dense breast tissue is a normal and routine finding on screening mammography, dense breast tissue is associated with an independent increased risk for breast cancer. It is well known that screening mammography has a decreased sensitivity for cancer detection in women with dense breasts. Over the past decade, there has been increased interest generated among patients, physicians, and legislators regarding how best to screen dense-breasted women culminating in 2009 with the passage of a breast density notification law in Connecticut...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317033/emerging-breast-imaging-technologies-on-the-horizon
#4
Srinivasan Vedantham, Andrew Karellas
Early detection of breast cancers by mammography in conjunction with adjuvant therapy has contributed to reduction in breast cancer mortality. Mammography remains the "gold-standard" for breast cancer screening but is limited by tissue superposition. Digital breast tomosynthesis and more recently, dedicated breast computed tomography have been developed to alleviate the tissue superposition problem. However, all of these modalities rely upon x-ray attenuation contrast to provide anatomical images, and there are ongoing efforts to develop and clinically translate alternative modalities...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29311416/average-glandular-dose-in-paired-digital-mammography-and-digital-breast-tomosynthesis-acquisitions-in-a-population-based-screening-program-effects-of-measuring-breast-density-air-kerma-and-beam-quality
#5
Bjørn Helge Østerås, Per Skaane, Randi Gullien, Anne Catrine Tregde Martinsen
The main purpose was to compare average glandular dose (AGD) for same-compression digital mammography (DM) and digital breast tomosynthesis (DBT) acquisitions in a population based screening program, with and without breast density stratification, as determined by automatically calculated breast density (QuantraTM). Secondary, to compare AGD estimates based on measured breast density, air kerma and half value layer (HVL) to DICOM metadata based estimates. AGD was estimated for 3819 women participating in the screening trial...
January 9, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29311005/preliminary-clinical-experience-with-a-combined-automated-breast-ultrasound-and-digital-breast-tomosynthesis-system
#6
Eric D Larson, Won-Mean Lee, Marilyn A Roubidoux, Mitchell M Goodsitt, Chris Lashbrook, Cynthia E Davis, Oliver D Kripfgans, Paul L Carson
We analyzed the performance of a mammographically configured, automated breast ultrasound (McABUS) scanner combined with a digital breast tomosynthesis (DBT) system. The GE Invenia ultrasound system was modified for integration with GE DBT systems. Ultrasound and DBT imaging were performed in the same mammographic compression. Our small preliminary study included 13 cases, six of whom had contained invasive cancers. From analysis of these cases, current limitations and corresponding potential improvements of the system were determined...
January 5, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29302784/initial-results-of-the-fusion-x-us-prototype-combining-3d-automated-breast-ultrasound-and-digital-breast-tomosynthesis
#7
Benedikt Schaefgen, Joerg Heil, Richard G Barr, Marcus Radicke, Aba Harcos, Christina Gomez, Anne Stieber, André Hennigs, Alexandra von Au, Julia Spratte, Geraldine Rauch, Joachim Rom, Florian Schütz, Christof Sohn, Michael Golatta
PURPOSE: To determine the feasibility of a prototype device combining 3D-automated breast ultrasound (ABVS) and digital breast tomosynthesis in a single device to detect and characterize breast lesions. METHODS: In this prospective feasibility study, the FUSION-X-US prototype was used to perform digital breast tomosynthesis and ABVS in 23 patients with an indication for tomosynthesis based on current guidelines after clinical examination and standard imaging. The ABVS and tomosynthesis images of the prototype were interpreted separately by two blinded experts...
January 4, 2018: European Radiology
https://www.readbyqxmd.com/read/29273223/personalised-screening-is-this-the-way-forward
#8
REVIEW
F J Gilbert, A Selamoglu
Screening with mammography has been implemented in many countries across the world with most offering 2-yearly examinations between the ages of 50-69 years. Robust modelling tools that include breast density and single nucleotide polymorphisms (SNPs) have been developed to predict which women are most likely to develop breast cancer. Mammographic sensitivity is poor in women with the densest category of breast tissue, and even women with heterogeneously dense tissue may benefit from additional supplemental imaging...
December 19, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29249352/quantitative-breast-density-analysis-using-tomosynthesis-and-comparison-with-mri-and-digital-mammography
#9
Woo Kyung Moon, Jie-Fan Chang, Chung-Ming Lo, Jung Min Chang, Su Hyun Lee, Sung Ui Shin, Chiun-Sheng Huang, Ruey-Feng Chang
BACKGROUND AND OBJECTIVE: Breast density at mammography has been used as markers of breast cancer risk. However, newly introduced tomosynthesis and computer-aided quantitative method could provide more reliable breast density evaluation. METHODS: In the experiment, 98 tomosynthesis image volumes were obtained from 98 women. For each case, an automatic skin removal was used and followed by a fuzzy c-mean (FCM) classifier which separated the fibroglandular tissues from other tissues in breast area...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29237146/digital-breast-tomosynthesis-with-synthesized-two-dimensional-images-versus-full-field-digital-mammography-for-population-screening-outcomes-from-the-verona-screening-program
#10
Francesca Caumo, Manuel Zorzi, Silvia Brunelli, Giovanna Romanucci, Rossella Rella, Loredana Cugola, Paola Bricolo, Chiara Fedato, Stefania Montemezzi, Nehmat Houssami
Purpose To examine the outcomes of a breast cancer screening program based on digital breast tomosynthesis (DBT) plus synthesized two-dimensional (2D) mammography compared with those after full-field digital mammography (FFDM). Materials and Methods This prospective study included 16 666 asymptomatic women aged 50-69 years who were recruited in April 2015 through March 2016 for DBT plus synthetic 2D screening in the Verona screening program. A comparison cohort of women screened with FFDM (n = 14 423) in the previous year was included...
December 13, 2017: Radiology
https://www.readbyqxmd.com/read/29230524/one-view-digital-breast-tomosynthesis-as-a-stand-alone-modality-for-breast-cancer-detection-do-we-need-more
#11
Alejandro Rodriguez-Ruiz, Albert Gubern-Merida, Mechli Imhof-Tas, Susanne Lardenoije, Alexander J T Wanders, Ingvar Andersson, Sophia Zackrisson, Kristina Lång, Magnus Dustler, Nico Karssemeijer, Ritse M Mann, Ioannis Sechopoulos
PURPOSE: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. MATERIALS AND METHODS: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT)...
December 11, 2017: European Radiology
https://www.readbyqxmd.com/read/29190506/mammographic-density-and-breast-cancer-risk-in-breast-screening-assessment-cases-and-women-with-a-family-history-of-breast-cancer
#12
Stephen W Duffy, Oliver W E Morrish, Prue C Allgood, Richard Black, Maureen G C Gillan, Paula Willsher, Julie Cooke, Karen A Duncan, Michael J Michell, Hilary M Dobson, Roberta Maroni, Yit Y Lim, Hema N Purushothaman, Tamara Suaris, Susan M Astley, Kenneth C Young, Lorraine Tucker, Fiona J Gilbert
BACKGROUND: Mammographic density has been shown to be a strong independent predictor of breast cancer and a causative factor in reducing the sensitivity of mammography. There remain questions as to the use of mammographic density information in the context of screening and risk management, and of the association with cancer in populations known to be at increased risk of breast cancer. AIM: To assess the association of breast density with presence of cancer by measuring mammographic density visually as a percentage, and with two automated volumetric methods, Quantra™ and VolparaDensity™...
January 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29186172/geometric-calibration-of-a-stationary-digital-breast-tomosynthesis-system-based-on-distributed-carbon-nanotube-x-ray-source-arrays
#13
Changhui Jiang, Na Zhang, Juan Gao, Zhanli Hu
Stationary digital breast tomosynthesis (sDBT) with distributed X-ray sources based on carbon nanotube (CNT) field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based approach with seven geometric parameters, all of which can be obtained from only one projection datum of the phantom...
2017: PloS One
https://www.readbyqxmd.com/read/29176921/foveated-model-observers-to-predict-human-performance-in-3d-images
#14
Miguel A Lago, Craig K Abbey, Miguel P Eckstein
We evaluate 3D search requires model observers that take into account the peripheral human visual processing (foveated models) to predict human observer performance. We show that two different 3D tasks, free search and location-known detection, influence the relative human visual detectability of two signals of different sizes in synthetic backgrounds mimicking the noise found in 3D digital breast tomosynthesis. One of the signals resembled a microcalcification (a small and bright sphere), while the other one was designed to look like a mass (a larger Gaussian blob)...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29174225/diagnostic-accuracy-of-digital-breast-tomosynthesis-in-the-evaluation-of-palpable-breast-abnormalities
#15
Jeffrey R Hawley, Justine K Kang-Chapman, Sarah E Bonnet, Amy L Kerger, Clayton R Taylor, Barbaros S Erdal
RATIONALE AND OBJECTIVES: The role of digital breast tomosynthesis (DBT) in evaluating palpable abnormalities has not been evaluated and its accuracy compared to 2D mammography is unknown. The purpose of this study was to evaluate combined 2D mammography, DBT, and ultrasound (US) at palpable sites. MATERIALS AND METHODS: Two breast imagers reviewed blinded consecutive cases with combined 2D mammograms and DBT examinations performed for palpable complaints. By consensus, 2D and DBT findings were recorded and compared to US...
November 23, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29173123/screening-digital-mammography-recall-rate-does-it-change-with-digital-breast-tomosynthesis-experience
#16
Olivia DiPrete, Ana P Lourenco, Grayson L Baird, Martha B Mainiero
Purpose To compare screening mammography recall rate, cancer detection rate (CDR), and positive predictive values (PPVs) for digital mammography before and after radiologist experience with digital breast tomosynthesis (DBT). Materials and Methods This retrospective study was approved by the institutional review board and compliant with HIPAA. The authors reviewed screening mammography audit data obtained from 2009 to 2014, during which 108 276 digital mammographic examinations were performed (50 062 before and 58 214 after experience with DBT)...
November 28, 2017: Radiology
https://www.readbyqxmd.com/read/29153373/improving-digital-breast-tomosynthesis-reading-time-a-pilot-multi-reader-multi-case-study-using-concurrent-computer-aided-detection-cad
#17
Corinne Balleyguier, Julia Arfi-Rouche, Laurent Levy, Patrick R Toubiana, Franck Cohen-Scali, Alicia Y Toledano, Bruno Boyer
PURPOSE: Evaluate concurrent Computer-Aided Detection (CAD) with Digital Breast Tomosynthesis (DBT) to determine impact on radiologist performance and reading time. MATERIALS AND METHODS: The CAD system detects and extracts suspicious masses, architectural distortions and asymmetries from DBT planes that are blended into corresponding synthetic images to form CAD-enhanced synthetic images. Review of CAD-enhanced images and navigation to corresponding planes to confirm or dismiss potential lesions allows radiologists to more quickly review DBT planes...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29132564/tomosynthesis-in-breast-cancer-imaging-how-does-it-fit-into-preoperative-evaluation-and-surveillance
#18
REVIEW
Mohammad Eghtedari, Catherine Tsai, Julie Robles, Sarah L Blair, Haydee Ojeda-Fournier
An important limitation of conventional two-dimensional mammography is the overlap of dense breast tissue obscuring masses. Digital breast tomosynthesis (DBT) has emerged as a mammographic technology that overcomes this limitation and is considered an overall better mammogram. DBT has been shown to detect significantly more breast cancer than conventional two-dimensional mammography, and to decrease the number of callbacks for diagnostic evaluation from screening mammography. Usually the callback evaluation is deemed to be overlap of tissue requiring no further management...
January 2018: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/29131762/strengths-and-weaknesses-of-synthetic-mammography-in-screening
#19
Linda Ratanaprasatporn, Sona A Chikarmane, Catherine S Giess
Synthetic mammography (SM) consists of two-dimensional images reconstructed from digital breast tomosynthesis (DBT) data. Unlike standard full-field digital mammography (FFDM), SM does not require additional radiation exposure. SM is being introduced in breast imaging centers because early clinical data demonstrate that synthetic images are comparable to FFDM in cancer detection, positive predictive values, and recall rates. SM has completely replaced FFDM in some practices. Thus, an understanding of SM and its strengths and weaknesses compared with those of FFDM is essential...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29129518/breast-cancer-screening-with-digital-breast-tomosynthesis-4-year-experience-and-comparison-with-national-data
#20
Huay-Ben Pan, Kam-Fai Wong, Anthony Yao, Giu-Cheng Hsu, Chen-Pin Chou, Huei-Lung Liang, Jer-Shyung Huang, Hung-Ju Li, Shu-Chin Wang, Tsung-Lung Yang
BACKGROUND: To determine if mammography combined with tomosynthesis (DBT) leads to superior performance in screening for breast cancer compared to digital mammography alone. METHODS: We retrospectively collected data from A) the results of population-based mammography-screening provided by the National Cancer Registry in Taiwan, and B) the results from all screening mammography performed with DBT from 2012 through 2015 at Veterans General Hospital Kaohsiung (VGHKS) since the institution of DBT at the end of 2011...
November 9, 2017: Journal of the Chinese Medical Association: JCMA
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