keyword
MENU ▼
Read by QxMD icon Read
search

Zinforo

keyword
https://www.readbyqxmd.com/read/28800526/identification-and-determination-of-related-substances-of-ceftaroline-fosamil-in-medicinal-product-by-high-performance-liquid-chromatography-with-diode-array-detection-and-tandem-mass-spectrometry
#1
Izabela Karpiuk, Katarzyna Michalska, Katarzyna Bus, Monika Kiljan, Stefan Tyski
Ceftaroline fosamil, the prodrug of ceftaroline, is an advanced-generation cephalosporin antibacterial agent approved for treatment in the European Union in 2012. The drug is dedicated to curing complicated skin and soft tissue infections and community-acquired pneumonia. The developed analytical method of high performance liquid chromatography (HPLC) followed by diode array detector (DAD) set at 243nm was used to identify and determine degradation products of ceftaroline fosamil. The elaborated method demonstrated good selectivity and linearity [r>0...
October 25, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27970753/zinforo-ceftaroline-fosamil-versus-other-empiric-initial-iv-antibiotics-for-complicated-skin-and-soft-tissue-infections-cssti-a-network-meta-analysis
#2
N Rao, E Gibson, R W Lawson, J J Goodall
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970750/zinforo-ceftaroline-fosamil-versus-other-empiric-antibiotics-for-moderate-to-severe-community-acquired-pneumonia-cap-in-adults-a-network-meta-analysis
#3
N Rao, E Gibson, R W Lawson, J J Goodall
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27766567/ceftaroline-fosamil-a-review-in-complicated-skin-and-soft-tissue-infections-and-community-acquired-pneumonia
#4
REVIEW
Lesley J Scott
Intravenous ceftaroline fosamil (Zinforo™), a prodrug that is rapidly converted to its active metabolite ceftaroline, is approved for use in adults and children (from 2 months of age) with complicated skin and soft tissue infections (cSSTIs) or community-acquired pneumonia (CAP). In several multinational trials, ceftaroline fosamil was an effective and generally well tolerated treatment in adult and paediatric patients with cSSTIs or CAP. In the phase 3 CANVAS trials, ceftaroline fosamil treatment was noninferior to vancomycin plus aztreonam in adults with cSSTIs...
November 2016: Drugs
https://www.readbyqxmd.com/read/27274260/recovery-of-a-10-year-old-girl-from-methicillin-resistant-staphylococcus-aureus-sepsis-in-response-to-low-dose-ceftaroline-treatment
#5
Stefan Borgmann, Beate Rieß, Thomas von Wernitz-Keibel, Matthias Bühler, Franziska Layer, Birgit Strommenger
A 9-year-old girl was severely injured in a car accident in Afghanistan, in which both her lower legs were badly damaged. She was treated at the Hospital of Ingolstadt (Klinikum Ingolstadt) after she had undergone initial surgery at an Indian hospital. Various bacterial species were isolated from multiple wounds, and methicillin-resistant Staphylococcus aureus (MRSA) was one among them. After the amputation of her lower legs, she developed MRSA sepsis, which was successfully treated with a relatively low dosage of ceftaroline (Zinforo(®)/Teflaro(®); 2×9 mg/kg/d), although the bacterial isolate's minimal inhibitory concentration (1...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/25429539/-zinforo%C3%A2-ceftaroline-fosamil-a-new-beta-lactam-cephalosporin-with-mrsa-activity
#6
COMPARATIVE STUDY
T Welte
No abstract text is available yet for this article.
November 2014: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/24600728/ceftaroline-fosamil-just-another-intravenous-antibiotic
#7
(no author information available yet)
Various antibiotics, especially cephalosporins, are used for empirical treatment of community-acquired pneumonia requiring hospitalisation and intravenous treatment, and for serious infections of the skin and soft tissues. When the infection is caused by bacteria that are resistant to common antibiotics, some antibiotics such as vancomycin are available. Ceftaroline (Zinforo, AstraZeneca) is a new cephalosporin intended for intravenous administration (as ceftaroline fosamil). It is authorised for the treatment of community-acquired pneumonia and for serious infections of the skin and soft tissues...
December 2013: Prescrire International
https://www.readbyqxmd.com/read/23801418/ceftaroline-fosamil-a-review-of-its-use-in-the-treatment-of-complicated-skin-and-soft-tissue-infections-and-community-acquired-pneumonia
#8
REVIEW
James E Frampton
Ceftaroline, the active metabolite of the prodrug ceftaroline fosamil (Zinforo, Teflaro), is an advanced-generation, parenteral cephalosporin with broad-spectrum antibacterial activity in vitro against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug resistant Streptococcus pneumoniae and Gram-negative bacteria, including Haemophilus influenzae and Moraxella catarrhalis, but not Pseudomonas aeruginosa. Ceftaroline has demonstrated a low potential for the selection of resistance in vitro for drug-resistant Gram-positive organisms, including MRSA, as well as for Gram-negative respiratory pathogens...
July 2013: Drugs
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"