keyword
MENU ▼
Read by QxMD icon Read
search

Thyroides

keyword
https://www.readbyqxmd.com/read/28231691/evaluation-of-diagnostic-performance-of-screening-thyroid-ultrasonography-us-and-imaging-findings-of-screening-detected-thyroid-cancer
#1
Jeongin Yoo, Hye Shin Ahn, Soo Jin Kim, Sung Hee Park, Mirinae Seo, Semin Chong
Purpose: To evaluate the diagnostic performance and cost of screening thyroid ultrasonography (US) in an asymptomatic population and determine the US features of screening-detected thyroid cancer. Materials and Methods: This study included 1845 asymptomatic participants who underwent screening thyroid US between March and August 2012 at the screening center in our hospital. We evaluated the diagnostic performance of screening thyroid US for thyroid cancer and the average cost of diagnosis for each patient...
February 24, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28231576/molecular-markers-involved-in-tumorigenesis-of-thyroid-carcinoma-focus-on-aggressive-histotypes
#2
Gustavo C Penna, Fernanda Vaisman, Mario Vaisman, Manuel Sobrinho-Simões, Paula Soares
Thyroid cancer derived from follicular cells (TCDFC) comprises well-differentiated (papillary and follicular) carcinoma, poorly differentiated carcinoma, and anaplastic carcinoma. Papillary thyroid carcinoma is the most common endocrine cancer, and its incidence is steadily increasing. Lethality and aggressiveness of TCDFC is inversely correlated with differentiation degree. In this review, an emphasis has been put on molecular markers involved in tumorigenesis of thyroid carcinoma with a focus on aggressive histotypes and the role of such biomarkers in predicting thyroid cancer outcome...
February 24, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28230832/specific-interactions-between-lectins-and-red-blood-cells-of-chornobyl-cleanup-workers-as-indicator-of-some-late-radiation-effects
#3
I S Karpova
AIM: Growing interest in lectins is based on their diagnostic and pharmacological potential, especially the ability to inhibit proliferation and initiate apoptosis of cancer cells. In our research microplate lectinoassay able to detect carbohydrate containing structures (receptors) on erythrocyte surface have been proposed for Chornobyl cleanup workers (1986) monitoring. It was expected to reveal specific abnormalities associated with pathological condition arising as a result of late radiation effects...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230825/molecular-markers-of-apoptosis-in-cancer-patients-exposed-to-ionizing-radiation-the-post-chornobyl-view
#4
A A Philchenkov, E K Balcer-Kubiczek
During the past three decades, the deleterious consequences of Chornobyl accident including carcinogenic effects in the people who were accidentally exposed to radiation have been intensively studied. In particular, recent studies provided increased knowledge of the molecular pathogenesis of thyroid tumors in children exposed to Chornobyl fallout. The risk of several forms of leukemia including myelodysplastic syndromes is elevated in Chornobyl liquidators. Furthermore, the upward trends of increases in a variety of other tumors including breast cancer, cancers of central nervous system and renal cancer have been reported in the persons exposed to Chornobyl fallout...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230823/polymorphism-of-dna-repair-gene-xpd-lys751gln-and-chromosome-aberrations-in-lymphocytes-of-thyroid-cancer-patients-exposed-to-ionizing-radiation-due-to-the-chornobyl-accident
#5
V M Shkarupa, O Y Mishcheniuk, S O Henyk-Berezovska, V O Palamarchuk, S V Klymenko
: The aim of this work was to analyze the relationship between polymorphisms of DNA repair gene XPD Lys751Gln and frequency and spectrum of chromosome aberrations in the culture of peripheral blood lymphocytes of thyroid cancer (TC) patients having been exposed to ionizing radiation due to the Chornobyl accident. MATERIALS AND METHODS: XPD Lys751Gln polymorphisms were detected by polymerase chain reaction in 102 TC patients including 38 patients exposed to ionizing radiation due to Chornobyl disaster (Chornobyl recovery workers, evacuees, and the residents of contaminated areas), 64 patients without history of ionizing radiation exposure and 45 healthy residents of Ukraine as control group...
December 2016: Experimental Oncology
https://www.readbyqxmd.com/read/28230092/rtfc-4931414p19rik-regulates-in-vitro-thyroid-differentiation-and-in-vivo-thyroid-function
#6
Yang Yu, Chang Liu, Junxia Zhang, Mimi Zhang, Wei Wen, Xianhui Ruan, Dapeng Li, Shuang Zhang, Ming Gao, Lingyi Chen
Thyroid is a one of the most important endocrine organs. Understanding the molecular mechanism underlying thyroid development and function, as well as thyroid diseases, is beneficial for the clinical treatment of thyroid diseases and tumors. Through genetic linkage analysis and exome sequencing, we previously identified an uncharacterized gene C14orf93 (RTFC, mouse homolog: 4931414P19Rik) as a novel susceptibility gene for familial non-medullary thyroid carcinoma, and demonstrated its function in promoting thyroid tumor...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230037/mutl-homolog-1-expression-in-thyroid-carcinoma-and-its-clinical-significance
#7
Yi Lu, Baocheng Jiang, Ye Yuan, Jianping Fei, Jiyuan Wang
OBJECTIVE: The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and its association with clinical pathological characteristics. MATERIALS AND METHODS: Forty thyroid cancer tissues and 22 partial paired normal thyroid tissues from 40 thyroid cancer patients who received surgery were collected in this study. MLH1 protein expression was tested by immunohistochemical method for the 40 cancer tissues and 22 partial paired normal thyroid tissues...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28229842/-thyroid-metastasis-as-the-initial-presentation-of-an-asymptomatic-clear-cell-renal-carcinoma
#8
Janine Carmelino, Ana Paula Tavares, Ana Crespo, José Mário Coutinho, António Lázaro, Vasco Ribeiro, Eduardo Barroso
INTRODUCTION: Clear cell renal carcinoma metastases to the thyroid gland are rare and only diagnosable after an immunohistochemistry analysis of the histological sample. The purpose of this article is to report a case of thyroid metastasis as the initial presentation of a clear cell renal carcinoma. CASE REPORT: Male patient with a solid nodule in the left lobe of the thyroid, 5.3 cm in diameter, suspicious of malignancy, for which a total thyroidectomy with central compartment lymphadenectomy was performed...
November 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28229578/growth-and-pubertal-development-in-adolescent-male-wrestlers
#9
İbrahim E Pişkin, Mustafa Gümüş, Taner Bayraktaroğlu, Tevfik C Akalin, Faruk Yamaner
BACKGROUND: Adolescence is a crucial period for linear growth, and sports training during this time may have positive or negative effects on some physiological processes as growth. The purpose of this study was to evaluate the effects of intense training during somatic growth on the onset of puberty and growth development in adolescent wrestlers. METHODS: Fifty adolescent male wrestlers and twenty-one sedentary healthy male controls aged between 13-15 years were selected...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28229360/thyroid-hormone-acting-via-tr%C3%AE-induces-expression-of-browning-genes-in-mouse-bone-marrow-adipose-tissue
#10
Richard C Lindsey, Subburaman Mohan
PURPOSE: Mutant hypothyroid mouse models have recently shown that thyroid hormone is critical for skeletal development during an important prepubertal growth period. Additionally, thyroid hormone negatively regulates total body fat, consistent with the well-established effects of thyroid hormone on energy and fat metabolism. Since bone marrow mesenchymal stromal cells differentiate into both adipocytes and osteoblasts and a relationship between bone marrow adipogenesis and osteogenesis has been predicted, we hypothesized thyroid hormone deficiency during the postnatal growth period increases marrow adiposity in mice...
February 22, 2017: Endocrine
https://www.readbyqxmd.com/read/28229359/thyroid-volume-and-serum-calcitonin-changes-during-pregnancy
#11
G Vannucchi, D Covelli, B Vigo, M Perrino, L Mondina, L Fugazzola
BACKGROUND: Pregnancy has a profound impact on thyroid homeostasis which results in change of thyroid function and thyroid volume (TV). Moreover, calcitonin (CT), and its gene-related peptide have been demonstrated to play an important role in the implantation process. PURPOSE: To evaluate changes in TV and serum CT levels during pregnancy. METHODS: One hundred and fifty-five pregnant women were consecutively enrolled at the first trimester of gestation and underwent clinical, biochemical and sonographic assessment at enrollment, at the second and third trimesters and at 6 months after delivery...
February 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28229097/pediatric-hypovitaminosis-d-molecular-perspectives-and-clinical-implications
#12
Rafiu Ariganjoye
Vitamin D, a secosteroid, is essential for the development and maintenance of healthy bone in both the adult and pediatric populations. Low level of 25-hydroxy vitamin D (25-(OH)-D) is highly prevalent in children worldwide and has been linked to various adverse health outcomes including rickets, osteomalacia, osteomalacic myopathy, sarcopenia, and weakness, growth retardation, hypocalcemia, seizure and tetany, autism, cardiovascular diseases, diabetes mellitus, cancers (prostate, colon, breast), infectious diseases (viral, tuberculosis), and autoimmune diseases, such as multiple sclerosis and Hashimoto's thyroiditis...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28228903/i-131-uptake-in-fat-necrosis-of-the-breast
#13
Malak Itani, David H Lewis
I-131 uptake in the breast has been described with a variety of normal and pathologic conditions. We present the case of a 38-year-old female who received 317 millicuries of radioactive I-131 treatment for papillary thyroid carcinoma. Post-treatment scan demonstrated I-131 uptake in an area of fat necrosis in the breast.
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28228654/low-ft3-a-possible-marker-of-frailty-in-the-elderly
#14
Aldo Bertoli, Alessia Valentini, Maria Assunta Cianfarani, Elena Gasbarra, Umberto Tarantino, Massimo Federici
INTRODUCTION: Frailty is associated with a functional decline of multiple physiological systems, of which they may be a cause or consequence. The objective of the study was to evaluate the prevalence of thyroid hormone modifications in elderly frail subjects and its relationship with frailty. STUDY POPULATION AND METHODS: An observational study was carried out at the University Hospital "Tor Vergata" in Rome among ambulatory and hospitalized patients. The study population consisted of 112 elderly subjects: 62 were hospitalized following hip fracture and 50 control subjects were outpatients...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28228636/progressive-ischemic-stroke-due-to-thyroid-storm-associated-cerebral-venous-thrombosis
#15
Natsumi Tanabe, Eiji Hiraoka, Masataka Hoshino, Gautam A Deshpande, Kana Sawada, Yasuhiro Norisue, Jumpei Tsukuda, Toshihiko Suzuki
BACKGROUND Cerebral venous thrombosis (CVT) is a rare but fatal complication of hyperthyroidism that is induced by the hypercoagulable state of thyrotoxicosis. Although it is frequently difficult to diagnose CVT promptly, it is important to consider it in the differential diagnosis when a hyperthyroid patient presents with atypical neurologic symptoms. CASE REPORT A 49-year-old Japanese female with unremarkable medical history came in with thyroid storm and multiple progressive ischemic stroke identified at another hospital...
February 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28226570/a-wearable-signal-acquisition-system-for-physiological-signs-including-throat-ppg
#16
Yizhou Zhong, Yun Pan, Ling Zhang, Kwang-Ting Cheng, Yizhou Zhong, Yun Pan, Ling Zhang, Kwang-Ting Cheng, Yizhou Zhong, Ling Zhang, Kwang-Ting Cheng, Yun Pan
This paper presents a wearable signal acquisition system, which can measure physiological signs, i.e., electrocardiogram (ECG) and photoplethysmogram (PPG). The system is comprised of two parts: (1) an ECG sensor implemented in the master board which will be mounted on the chest and, (2) a combined PPG and motion sensor implemented in the slave board which will be worn around the neck area. The single-lead ECG, the single-channel PPG, and the 3-channel accelerometer signals are all sampled at 200Hz, and transmitted to an Android app through Bluetooth® low energy (BLE) in real time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226412/rage-polymorphisms-and-oxidative-stress-levels-in-hashimoto-s-thyroiditis
#17
Maria Giannakou, Katerina Saltiki, Emily Mantzou, Eleni Loukari, Georgios Philippou, Konstantinos Terzidis, Kiriaki Lili, Charalampos Stavrianos, Miltiades Kyprianou, Maria Alevizaki
BACKGROUND: Polymorphisms of the receptor for advanced glycation end products (RAGE) gene have been studied in various autoimmune disorders, but not in Hashimoto's thyroiditis. Also, increased oxidative stress has been described in patients with Hashimoto's thyroiditis. The aim of the present study was to investigate the possible role of two common RAGE polymorphisms (-429T>C, -374T>A) in Hashimoto's thyroiditis; in parallel we studied oxidative stress levels. MATERIALS AND METHODS: 300 consecutive euthyroid women were examined and classified into three groups: Hashimoto's thyroiditis with treatment (n=96), Hashimoto's thyroiditis without treatment (n=109) and controls (n=95)...
February 22, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28226001/recombinant-human-tsh-versus-thyroid-hormone-withdrawal-in-adjuvant-therapy-with-radioactive-iodine-of-patients-with-papillary-thyroid-carcinoma-and-clinically-apparent-lymph-node-metastases-not-limited-to-the-central-compartment-cn1b
#18
Pedro Weslley Rosario, Gabriela Franco Mourão, Maria Regina Calsolari
Objective: To compare the short- and long-term outcomes of adjuvant therapy with radioactive iodine (RAI) preceded by the administration of recombinant human TSH (rhTSH) versus thyroid hormone withdrawal (THW) in patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central neck compartment (cN1b). Subjects and methods: The sample consisted of 178 cN1b patients at intermediate risk who underwent total thyroidectomy with apparently complete tumor resection [including postoperative ultrasonography (US) without anomalies] and who received adjuvant therapy with RAI (30-100 mCi) preceded by the administration of rhTSH (n = 91) or THW (n = 87)...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28226000/efficacy-and-safety-of-a-single-radiofrequency-ablation-of-solid-benign-non-functioning-thyroid-nodules
#19
Roberto Cesareo, Andrea Palermo, Valerio Pasqualini, Carla Simeoni, Alessandro Casini, Giuseppe Pelle, Silvia Manfrini, Giuseppe Campagna, Roberto Cianni
Objective: The objective of our study is to evaluate the clinical outcomes and safety of radiofrequency thermal ablation (RFA) for benign thyroid nodules (BTNs) over a 1-year follow-up. Subjects and methods: This is a monocentric retrospective study. Forty-eight patients with solid, non-functioning BTNs were treated by RFA using a 17G internally cooled electrode. We categorized thyroid nodules as small (≤ 12 mL), medium (12 to 30 mL), or large (over 30 mL). BTNs volume reduction, thyroid function, cosmetic and compressive score changes and side effect evaluation at 6 and 12 months were evaluated...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225999/radioactive-iodine-refractory-differentiated-thyroid-cancer-an-uncommon-but-challenging-situation
#20
Angelica Schmidt, Laura Iglesias, Michele Klain, Fabián Pitoia, Martin J Schlumberger
Radioiodine (RAI)-refractory thyroid cancer is an uncommon entity, occurring with an estimated incidence of 4-5 cases/year/million people. RAI refractoriness is more frequent in older patients, in those with large metastases, in poorly differentiated thyroid cancer, and in those tumors with high 18-fluordeoxyglucose uptake on PET/CT. These patients have a 10-year survival rate of less than 10%. In recent years, new therapeutic agents with molecular targets have become available, with multikinase inhibitors (MKIs) being the most investigated drugs...
February 13, 2017: Archives of Endocrinology and Metabolism
keyword
keyword
21343
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"