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https://www.readbyqxmd.com/read/29156005/abiofilm-a-resource-of-anti-biofilm-agents-and-their-potential-implications-in-targeting-antibiotic-drug-resistance
#1
Akanksha Rajput, Anamika Thakur, Shivangi Sharma, Manoj Kumar
Biofilms play an important role in the antibiotic drug resistance, which is threatening public health globally. Almost, all microbes mimic multicellular lifestyle to form biofilm by undergoing phenotypic changes to adapt adverse environmental conditions. Many anti-biofilm agents have been experimentally validated to disrupt the biofilms during last three decades. To organize this data, we developed the 'aBiofilm' resource (http://bioinfo.imtech.res.in/manojk/abiofilm/) that harbors a database, a predictor, and the data visualization modules...
November 16, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29155255/the-role-of-epigenetics-in-cardiovascular-health-and-aging-a-focus-on-physical-activity-and-nutrition
#2
REVIEW
Robert G Wallace, Laura C Twomey, Marc-Antoine Custaud, Jonathan Turner, Niall Moyna, Philip M Cummins, Ronan P Murphy
The cardiovascular system is responsible for transport of blood and nutrients to tissues, and is pivotal to the physiological health and longevity. Epigenetic modification is a natural, age-associated process resulting in highly contextualised gene expression with clear implications for cell differentiation and disease onset. Biological/epigenetic age is independent of chronological age, constituting a highly reflective snapshot of an individual's overall health. Accelerated vascular aging is of major concern, effectively lowering disease threshold...
November 16, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29155225/a-systematic-review-of-the-long-term-effectiveness-of-work-based-lifestyle-interventions-to-tackle-overweight-and-obesity
#3
REVIEW
Greta Tam, May P S Yeung
Obesity is one of the five leading global risks for mortality, accounting for 5% of deaths worldwide. Workplace health promotion programs have the potential to deliver population-level interventions combining physical activity and exercise. However, there is no recent critical review of trials on long-term effectiveness of multicomponent lifestyle interventions in the workplace targeting obesity. Good quality evidence is needed to develop optimal strategies to tackle adult obesity. 1035 studies were retrieved by literature search in MEDLINE, Embase, PSYCH INFO and Cochrane library from 2005 to September 2016...
November 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29154974/prostate-cancer-health-disparities-an-immuno-biological-perspective
#4
Sanjay Kumar, Rajesh Singh, Shalie Malik, Upender Manne, Manoj Mishra
Prostate cancer (PCa) is the most commonly diagnosed malignancy in males, and, in the United States, is the second leading cause of cancer-related death for men older than 40 years. There is a higher incidence of PCa for African Americans (AAs) than for European-Americans (EAs). Investigations related to the incidence of PCa-related health disparities for AAs suggest that there are differences in the genetic makeup of these populations. Other differences are environmentally induced (e.g., diet and lifestyle), and the exposures are different...
November 15, 2017: Cancer Letters
https://www.readbyqxmd.com/read/29154605/psychological-symptoms-and-subsequent-healthy-lifestyle-after-a-colorectal-cancer-diagnosis
#5
Claudia Trudel-Fitzgerald, Shelley S Tworoger, Elizabeth M Poole, Xuehong Zhang, Edward L Giovannucci, Jeffrey A Meyerhardt, Laura D Kubzansky
OBJECTIVE: Although medical professionals recommend lifestyle changes following a colorectal cancer (CRC) diagnosis to improve outcomes, such changes are not consistently implemented. This study examines whether higher distress is associated with lower likelihood of engaging in favorable behaviors after CRC diagnosis. METHOD: Women from the Nurses' Health Study prospective cohort who completed anxiety (n = 145) and depression (n = 227) symptom scales within 4 years after receiving a CRC diagnosis were included...
November 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29154166/sickness-absence-indicating-depressive-symptoms-of-working-population-in-south-korea
#6
Cheolmin Shin, Young-Hoon Ko, Seoyoung Yoon, Sang Won Jeon, Chi-Un Pae, Yong-Ku Kim, Ashwin A Patkar, Changsu Han
BACKGROUND: Sickness absence has been regarded as an important indicator of workers' health and work productivity. This study is aimed to evaluate the association between depressive symptoms and sickness absence in workers of South Korea. METHODS: We used nationwide cross-sectional survey data from 2889 individuals in the working population aged over 19 years in South Korea. Depressive symptoms were measured using Patient Health Questionnaire-9 (PHQ-9). Those respondents who scored above 10 on PHQ-9 were regarded as having depressive symptoms...
November 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29153315/what-are-the-keys-to-a-longer-happier-life-answers-from-five-decades-of-health-psychology-research
#7
Blair T Johnson, Rebecca L Acabchuk
RATIONALE: It has long been known that factors of the mind and of interpersonal relationships influence health, but it is only in the last 50 years that an independent scientific field of health psychology appeared, dedicated to understanding psychological and behavioral processes in health, illness, and healthcare. OBJECTIVE AND METHOD: This article (a) reviews important research that answers the question of how human beings can have longer, happier lives; and (b) highlights trends in health psychology featuring articles in Social Science & Medicine as well as other related literature...
November 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29153269/vitamin-d-pathway-gene-polymorphisms-influenced-vitamin-d-level-among-pregnant-women
#8
Bule Shao, Shuying Jiang, Xiamusiye Muyiduli, Shuojia Wang, Minjia Mo, Minchao Li, Zhaopin Wang, Yunxian Yu
AIMS: To explore the relationship between vitamin D pathway genes, gene-environment interactions and vitamin D level among southeast Chinese pregnant women. METHODS: 759 participants from Zhoushan Pregnant Women Cohort (ZPWC) study, were enrolled from August 2011 to April 2014 in China. Plasma 25(OH)D levels and genetic variants in vitamin D pathway (NADSYN1/DHCR7, GC, CYP3A4, CYP2R1, CYP27A1, CYP27B1, VDR, CYP24A1, and LRP2) were measured using the blood sample collected at the first trimester...
November 7, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29152889/systemic-use-of-antibiotics-and-risk-of-diabetes-in-adults-a-nested-case-control-study-of-alberta-s-tomorrow-project
#9
Ming Ye, Paula J Robson, Dean T Eurich, Jennifer E Vena, Jian-Yi Xu, Jeffrey A Johnson
AIMS: Previous observational studies using administrative health records have suggested an increased risk of diabetes with use of antibiotics. However, unmeasured confounding factors may explain these results. This study characterized the association between systemic use of antibiotics and risk of diabetes in a cohort of adults in Canada, accounting for both clinical and self-reported disease risk factors. MATERIALS AND METHODS: In this nested case-control study, we used data from Alberta's Tomorrow Project (ATP), a longitudinal cohort study in Canada, and the linked administrative health records (2000-2015)...
November 20, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29151591/us-health-policy-and-prescription-drug-coverage-of-fda-approved-medications-for-the-treatment-of-obesity
#10
G Gomez, F C Stanford
OBJECTIVE: Obesity is now the most prevalent chronic disease in the United States, which amounts to an estimated $147 billion in health care spending annually. The Affordable Care Act (ACA) enacted in 2010, included provisions for private and public health insurance plans that expanded coverage for lifestyle/behavior modification and bariatric surgery for the treatment of obesity. Pharmacotherapy, however, has not been included despite their evidence-based efficacy. We set out to investigate the coverage of FDA-approved medications for obesity within Medicare, Medicaid, and ACA-established marketplace health insurance plans...
November 20, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29151281/skeletal-muscle-performance-and-ageing
#11
REVIEW
Michael Tieland, Inez Trouwborst, Brian C Clark
The world population is ageing rapidly. As society ages, the incidence of physical limitations is dramatically increasing, which reduces the quality of life and increases healthcare expenditures. In western society, ~30% of the population over 55 years is confronted with moderate or severe physical limitations. These physical limitations increase the risk of falls, institutionalization, co-morbidity, and premature death. An important cause of physical limitations is the age-related loss of skeletal muscle mass, also referred to as sarcopenia...
November 19, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29151050/physical-activity-in-former-elite-cricketers-and-strategies-for-promoting-physical-activity-after-retirement-from-cricket-a-qualitative-study
#12
Stephanie R Filbay, Felicity L Bishop, Nicholas Peirce, Mary E Jones, Nigel K Arden
OBJECTIVES: The health benefits of professional sport dissipate after retirement unless an active lifestyle is adopted, yet reasons for adopting an active or inactive lifestyle after retirement from sport are poorly understood. Elite cricket is all-encompassing, requiring a high volume of activity and unique physical demands. We aimed to identify influences on physical activity behaviours in active and insufficiently active former elite cricketers and provide practical strategies for promoting physical activity after cricket retirement...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150762/seasonal-influence-on-adherence-to-and-effects-of-an-interval-walking-training-program-on-sedentary-female-college-students-in-japan
#13
Aiko Tanabe, Shizue Masuki, Ken-Ichi Nemoto, Hiroshi Nose
Habitual exercise training is recommended to young people for their health promotion, but adherence may be influenced by atmospheric temperature (T a ) if performed outdoors. We compared the adherence to and the effects of a home-based interval walking training (IWT) program on sedentary female college students between winter and summer. For summer training over 176 days, 48 subjects (18-22 years old) were randomly divided into two groups: the control group (CNTsummer, n = 24), which maintained a sedentary lifestyle as before, and the IWT group (IWTsummer, n = 24), which performed IWT while energy expenditure was monitored by accelerometry...
November 17, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29150753/psychological-aspects-of-obesity-in-children-and-adolescents
#14
Rajesh Sagar, Tanu Gupta
Childhood obesity is multi factorial health condition, so the simple evaluation of body fat will not be sufficed to manage the global epidemic of childhood obesity. Literature consistently provides evidence for physical health risks associated with childhood obesity; however in recent times, mental health of the obese children has also gained attention of the researchers as well as clinicians. Obese children experience number of psycho-social problems that significantly affect their quality of life and wellbeing...
November 18, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29150678/dog-ownership-and-the-risk-of-cardiovascular-disease-and-death-a-nationwide-cohort-study
#15
Mwenya Mubanga, Liisa Byberg, Christoph Nowak, Agneta Egenvall, Patrik K Magnusson, Erik Ingelsson, Tove Fall
Dogs may be beneficial in reducing cardiovascular risk in their owners by providing social support and motivation for physical activity. We aimed to investigate the association of dog ownership with incident cardiovascular disease (CVD) and death in a register-based prospective nation-wide cohort (n = 3,432,153) with up to 12 years of follow-up. Self-reported health and lifestyle habits were available for 34,202 participants in the Swedish Twin Register. Time-to-event analyses with time-updated covariates were used to calculate hazard ratios (HR) with 95% confidence intervals (CI)...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150513/high-prevalence-and-genetic-diversity-of-large-phicd211-phicdif1296t-like-prophages-in-clostridioides-difficile
#16
Julian R Garneau, Ognjen Sekulovic, Bruno Dupuy, Olga Soutourina, Marc Monot, Louis-Charles Fortier
Clostridioides difficile (formerly Clostridium difficile) is a pathogenic bacterium displaying great genetic diversity. A significant proportion of this diversity is due to the presence of integrated prophages. Here, we provide an in-depth analysis of phiCD211, also known as phiCDIF1296T, the largest phage identified in C. difficile so far, with a genome of 131-kbp. It shares morphological and genomic similarity with other large siphophages like phage 949 infecting Lactococcus lactis and phage c-st infecting Clostridium botulinum...
November 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29150466/are-the-early-predictors-of-long-term-work-absence-following-injury-time-dependent-results-from-the-prospective-outcomes-of-injury-study
#17
Rebbecca Lilley, Gabrielle Davie, Sarah Derrett
OBJECTIVES: Few studies examine the influence of early predictors of work absence beyond 12 months following injury or the time-dependent relative importance of these factors. This study aimed to identify the most important sociodemographic, occupational, health, lifestyle and injury predictors of work absence at 12 and 24 months following injury and to examine changes in the relative importance of these over time. DESIGN: Prospective cohort study. SETTING: The Prospective Outcomes of Injury Study, New Zealand...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150168/exploring-the-path-between-depression-anxiety-and-10-year-cardiovascular-disease-incidence-among-apparently-healthy-greek-middle-aged-adults-the-attica-study
#18
Natasa Kollia, Demosthenes Panagiotakos, Ekavi Georgousopoulou, Christina Chrysohoou, Mary Yannakoulia, Christodoulos Stefanadis, Somnath Chatterji, Josep Maria Haro, Charalabos Papageorgiou, Christos Pitsavos
OBJECTIVES: Although there is substantial evidence that psychological factors play an important role in the onset and course of cardiovascular disease (CVD), less is known about their combined effect and the pathways by which they affect cardiovascular health. The present work aimed to prospectively explore the effects of depression and anxiety on the 10-year CVD incidence, in relation to other lifestyle determinants, as linking factors in the context of the ATTICA study. Study design/Main outcome measures: The ATTICA study is a population-based, health and nutrition prospective cohort study (2002-2012), during which 853 middle-aged participants without a history of CVD [453 men (aged 45±13years) and 400 women (aged 44±18years)], underwent psychological evaluations at enrollment...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29149907/mapping-evidence-on-the-distribution-of-human-papillomavirus-related-cancers-in-sub-saharan-africa-scoping-review-protocol
#19
Bridget K M Lekoane, Tivani P Mashamba-Thompson, Themba G Ginindza
BACKGROUND: Despite the introduction of HPV vaccines, the incidence of HPV-related cancers (cervical, penile, anal, vulvar, vagina, head, and neck) in sub-Saharan Africa has been rising. The increasing incidence of these HPV-related cancers has been attributed to changes in lifestyle-related risk factors, most notably sexual behavior. The main objective of this study is to map evidence on the distribution of HIV-related cancers in sub-Saharan Africa (SSA). METHODS AND ANALYSIS: We will conduct a scoping review to explore, describe, and map literature on the distribution of HPV-related cancers in sub-Saharan Africa...
November 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29149271/rangatahi-t%C3%A5-rangatira-innovative-health-promotion-in-aotearoa-new-zealand
#20
Christina Severinsen, Angelique Reweti
Rangatahi Tū Rangatira (R2R) is a national health promotion programme in Aotearoa New Zealand which aims to promote cultural and physical wellbeing for rangatahi (young people) and their whānau (family). Grounded in tikanga Māori, the programme focuses on total wellbeing, leadership and cultural awareness providing rangatahi opportunities to increase their participation in physical activity and cultural knowledge through ngā taonga tākaro (Māori ancestral games). This paper focuses on an evaluation of this innovative health promotion programme focussing on the delivery of R2R by a local iwi provider in a rural area...
November 14, 2017: Health Promotion International
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