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S E van Oostendorp, E C T H Tan, L M G Geeraedts
INTRODUCTION: Exsanguination following trauma is potentially preventable. Extremity tourniquets have been successfully implemented in military and civilian prehospital care. Prehospital control of bleeding from the torso and junctional area's remains challenging but offers a great potential to improve survival rates. This review aims to provide an overview of potential treatment options in both clinical as preclinical state of research on truncal and junctional bleeding. Since many options have been developed for application in the military primarily, translation to the civilian situation is discussed...
2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
R I Zhdanov, A N Doinikova, S I Zhdanova, Yu V Chernokhvostov, E S Gadzhieva, V G Dvoenosov
The work is aimed to an assessment of the correlation between of autonomic nervous system tone and the level of reactivity of the students' cardiovascular system and hemostasis system under examination stress. It was found that the students under exam stress are characterized with high values of respiration rate and with lower ones of tidal volume. The value of respiratory minute volume decreases in male students due to the bronchoconstrictor effects of stress at the tracheobronchial tree. This finding confirms a statistically significant reduction in the flow of small, medium and large bronchi, indicating an increased parasympathetic nervous system tone...
March 2016: Zhurnal Vyssheĭ Nervnoĭ Deiatelnosti Imeni I P Pavlova
M Soledad Cabrera-Ramírez, M Sandra Domínguez-Sosa, Silvia Andrea Borkoski-Barreiro, Juan Carlos Falcón-González, Ángel Ramos-Macías
INTRODUCTION AND OBJECTIVES: Endoscopic sinus surgery is currently the surgical procedure chosen in cases of sinonasal polyposis refractory to medical treatment. The aim of this study was to show our experience in managing such patients operated using endoscopic sinus surgery. METHOD: A retrospective study of 246 patients with chronic rhinosinusitis and nasal polyps who were operated by endoscopic surgery. We studied the characteristics of the population, symptoms, grade of affectation, complications and recurrences...
August 8, 2016: Acta Otorrinolaringológica Española
D M Manas, J Figueras, D Azoulay, J C Garcia Valdecasas, J French, E Dixon, N O'Rourke, N Grovale, V Mazzaferro
BACKGROUND: Reduction of perioperative blood loss and intraoperative transfusion are two major factors associated with improving outcomes in liver surgery. There is currently no consensus as to the best technique to achieve this. METHODS: An international Panel of Experts (EP), made up of hepatobiliary surgeons from well-known high-volume centres was assembled to share their experience with regard to the management of blood loss during liver resection surgery. The process included: a review of the current literature by the panel, a face-to-face meeting and an on-line survey completed by the EP prior to and following the face-to-face meeting, based on predetermined case scenarios...
October 2016: European Journal of Surgical Oncology
I A Anikhovskaya, V G Dvoenosov, R I Zhdanov, A A Koubatiev, I A Mayskiy, M M Markelova, M V Meshkov, O N Oparina, I M Salakhov, M Yu Yakovlev
INTRODUCTION: General adaptation syndrome (GAS), the basis of the development of which is stress phenomenon, is an essential component of the pathogenesis of many diseases and syndromes. However, the patho genesis of GAS hitherto is considered exclusively from the endocrinological viewpoint. This relates primarily to the initial phase of the GAS, a clinical model for the study of which may be psycho-emotional stress (PES), which we studied using three groups of volunteers. METHODS: The first one consists of 25 students who were waiting for unaccustomed physical activity (17 men) and play debut on the stage (8 women)...
October 2015: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
Yves Brand, Vairavan Narayanan, Narayanan Prepageran, Vicknes Waran
OBJECTIVE: To share our experience with a new delivery system for the flowable hemostatic matrix, FloSeal, in endoscopic and microscopic skull base surgery. METHODS: We prospectively analyzed the use of FloSeal with a hemostatic delivery system in transnasal endoscopic and microscopic skull base procedures performed at the authors' institution from January 1, 2015, to June 30, 2015. In all cases the number of aliquots was noted for the entire operation, and the total number of FloSeal ampules of 5 mL was also recorded...
June 2016: World Neurosurgery
Xinyi Shi, Qiang Fang, Miao Ding, Jing Wu, Fei Ye, Zhengbing Lv, Jia Jin
To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic function experiment, it was found that CSCM could facilitate platelet adherence, platelet aggregation, and platelet activation in vitro. Besides, the maximum swelling of CSCM submerged in PBS for 50 min was over 300% of that exhibited by commercial hemostatic compound microporous polysaccharide haemostatic powder (CMPHP)...
February 2016: Journal of Biomaterials Applications
A D Ma, C M Kessler, H A B Al-Mondhiry, R Z Gut, D L Cooper
INTRODUCTION: Acquired haemophilia (AH) is a rare disorder caused by autoantibodies against factor VIII. AIM: The Hemostasis & Thrombosis Research Society (HTRS) Registry was used to monitor the safety of recombinant FVII (rFVIIa). This study aims to report data from the HTRS Registry regarding safety and efficacy of rFVIIa for haemostatic management of surgeries and other invasive procedures in patients with AH. METHODS: For each rFVIIa-treated procedure, the initial dose, total dose, average infused dose, number of doses and treatment duration were calculated...
January 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
V A Reva, M A Litinskii, A V Denisov, M V Sokhranov, S Yu Telitskii, I M Samokhvalov
Today self-expanding polymers are considered as the most promising as means for intracavitary hemostasis in case of continuing bleeding after trauma. Testing of domestic open-cell polyurethane foam composition "Locus" was carried out on the developed experimental model simulating liver trauma of V degree. After damaging 6 experimental rabbits were injected intraperitoneally with 80 ml of the composition. 5 experimental rabbits were included into to control group (haemostatic agent was not given). Estimated blood loss was 111-124 ml...
April 2015: Voenno-medit︠s︡inskiĭ Zhurnal
Alba León Jorba, Miguel López Cuiña, Alessandro Principe, Gloria Villalba Martínez
Hydrogen peroxide (H2O2) is commonly used as a haemostatic agent in all type of surgeries. Some adverse effects have been described related to its use. However, only very few cases are published in the literature of a stroke associated with the application of this agent directly to the brain. We present the case of a patient operated on for a right insular tumor with the assistance of intraoperative neurophysiological monitoring who developed a postoperative severe hemiparesis caused by a stroke in left middle cerebral artery territory due to the irrigation with H2O2...
2015: Turkish Neurosurgery
Grzegorz Raba, Kamil Szczupak, Piotr Stabiszewski, Wojciech Skibinski
INTRODUCTION: Haemorrhages from the genital tract remain a major threat to the life of patients with advanced cervical cancer. It is possible to achieve haemostasis by both surgical techniques and the procedure of endovascular uterine artery embolization. However, in some women with loco-regionally advanced cervical cancer the obliteration of the uterine arteries is not effective. AIM: Evaluation of morphological changes in uterine arteries in patients with advanced cervical cancer and comparison of their changes with the achieved haemostatic effect of obliteration...
July 2015: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Agnieszka Morel, Michał Bijak, Elżbieta Miller, Joanna Rywaniak, Sergiusz Miller, Joanna Saluk
Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of MS, our study targets selective group of late stage secondary progressive MS patients. The presented work is concerned with the reactivity of blood platelets in primary hemostasis in SP MS patients. 50 SP MS patients and 50 healthy volunteers (never diagnosed with MS or other chronic diseases) were examined to evaluate the biological activity of blood platelets (adhesion, aggregation), especially their response to the most important physiological agonists (thrombin, ADP, and collagen) and the effect of oxidative stress on platelet activity...
2015: Oxidative Medicine and Cellular Longevity
Saeed Nouri, Mohammad Reza Sharif
BACKGROUND: Controlling parenchymal hemorrhage, especially in liver parenchyma, despite all the progress in surgical science, is still one of the challenges surgeons face. Therefore, search for an effective method to control hepatic bleeding is an important research priority. OBJECTIVES: This study attempted to determine the haemostatic effect of ferric sulfate and compare it with the standard method (suturing technique). MATERIALS AND METHODS: In this animal model study, 60 male Wistar rats were used...
February 2015: Trauma Monthly
Anna Frątczak, Krzysztof Kujawski, Anna Gluba-Brzózka, Jacek Rysz
UNLABELLED: Bleeding from the upper gastrointestinal tract, despite the prevalence of endoscopic examinations and endoscopic methods of bleeding control, remains a significant problem. Available data indicate nondecreasing mortality of patients with active bleeding from the upper gastrointestinal tract although it is commonly known that such patients require fast endoscopic diagnosis and urgent treatment. Currently, the choice of method of endoscopic treatment of bleeding depends mostly on its availability and the decision of the physician performing the procedure...
February 2015: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Saeed Nouri, Mohammad Reza Sharif, Fatemeh Tabatabaei, Shima Farokhi
BACKGROUND: Despite all progresses in surgical science, bleeding caused by traffic accidents is still a challenge for surgeons to save patients' lives. Therefore, introducing an effective method to control external bleeding is an important research priority. OBJECTIVES: This study aimed to compare haemostatic effect of zinc chloride and simple suturing to control external bleeding. MATERIALS AND METHODS: In this animal model study, 60 male Wistar rats were used...
September 2014: Nursing and Midwifery Studies
Zp Tsiamoulos, C Hancock, Pd Sibbons, Bp Saunders
INTRODUCTION: Current endoscopic knives utilise mono-polar energy to incise the mucosa, dissect the submucosa and coagulate bleeding vessels. Monopolar devices have proven efficacy but remain technically challenging to use with the risk of major complications. METHODS: A new bipolar endoscopic device "Speedboat-RS2, (S-RS2) Creo Medical Ltd, UK" was compared to a standard mono-polar endoscopic device (Flush-knife-BT/F-BT/Fujifilm, Japan) for endoscopic submucosal dissection (ESD) in the porcine colon...
June 2014: Gut
Saeed Nouri, Mohammad Reza Sharif
BACKGROUND: Controlling parenchymal hemorrhage especially in liver parenchyma, despite all the progress in surgical science, is still one of the challenges surgeons face saving patients' lives and there is a research challenge among researchers in this field to introduce a more effective method. OBJECTIVES: This study attempts to determine the haemostatic effect of ferric chloride and compare it with that of the standard method (suturing technique) in controlling bleeding from liver parenchymal tissue...
June 2014: Hepatitis Monthly
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