Liu-Yun Wu, Yuek Ling Chai, Irwin K Cheah, Rachel S L Chia, Saima Hilal, Thiruma V Arumugam, Christopher P Chen, Mitchell K P Lai
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous condition, arising from diverse microvascular mechanisms. These lead to chronic cerebrovascular dysfunction and carry a substantial risk of subsequent stroke and vascular cognitive impairment in aging populations. Owing to advances in neuroimaging, in vivo visualization of cerebral vasculature abnormities and detection of CSVD, including lacunes, microinfarcts, microbleeds and white matter lesions, is now possible, but remains a resource-, skills- and time-intensive approach...
March 2024: Ageing Research Reviews