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https://www.readbyqxmd.com/read/29782890/novel-dental-adhesive-resin-with-crack-self-healing-antimicrobial-and-remineralization-properties
#1
Shichao Yue, Junling Wu, Qiang Zhang, Ke Zhang, Michael D Weir, Satoshi Imazato, Yuxing Bai, Hockin H K Xu
OBJECTIVES: Secondary caries at the tooth-restoration margins is a primary reason for restoration failure. Cracks at the margins lead to leakage which can trap bacteria, producing acids to cause caries. To date, there has been no report on developing an adhesive resin that has self-healing, antibacterial and remineralizing capabilities. The objectives of this study were to: (1) develop the first self-healing adhesive with antimicrobial and remineralizing capabilities, and (2) investigate the effects of incorporating microcapsules, dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of amorphous calcium phosphate (NACP) for the first time...
May 18, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29782221/effect-of-surface-sealant-reapplication-on-clinical-performance-of-hema-containing-and-hema-free-self-etch-adhesives-two-year-results
#2
N Tekçe, M Demirci, S Tuncer, S A Göktürk
PURPOSE: To evaluate the clinical performance of one-step self-etch adhesives over two years with and without the application of a surface sealant. METHODS AND MATERIALS: In total, 160 restorations in 40 patients were performed for occlusal caries. Each patient received four Class I restorations, which included a 2-hydroxyethyl methacrylate (HEMA)-containing (Clearfil S3 Bond) and HEMA-free (G-aenial Bond) one-step self-etch adhesive system with and without surface sealant...
May 21, 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29779627/in-vitro-assessment-of-ribose-modified-two-step-etch-and-rinse-dentine-adhesive
#3
U Daood, J K H Tsoi, P Neelakantan, J P Matinlinna, H A K Omar, M Al-Nabulsi, A S Fawzy
OBJECTIVE: Collagen fibrils aid in anchoring resin composite restorations to the dentine substrate. The aim of the study was to investigate effect of non-enzymatic glycation on bond strength and durability of demineralized dentine specimens in a modified two-step etch-and-rinse dentine adhesive. METHODS: Dentine surfaces were etched with 37% phosphoric acid, bonded with respective in vitro ethanol and acetone adhesives modified with (m/m, 0, 1%, 2% and 3% ribose), restored with restorative composite-resin, and sectioned into resin-dentine slabs and beams to be stored for 24h or 12 months in artificial saliva...
May 17, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29779282/-effect-of-bone-morphogenetic-protein-4-overexpression-on-the-biological-activity-of-mouse-induced-pluripotent-stem-cells
#4
Jin Qiu, Hui-Yu Zhang, Li Liu, Ying-Hui Tan
OBJECTIVE: This study aimed to construct the expression of bone morphogenetic protein-4 (BMP4) lentiviral vector gene and explore its influence on the biological activity of mouse induced pluripotent stem (iPS) cells. METHODS: iPS cell lines stably overexpressing BMP4 were constructed by lentivirus transfection (BMP4-overexpressing group). Cells without transfection served as the blank group, and cells with only vector transfection served as the empty-vector group...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29778987/effect-of-ethanol-dissolved-rhodamine-b-marker-on-mechanical-properties-of-non-simplified-adhesives
#5
Camila Moreira Machado, Odair Bim Júnior, Marina Ciccone Giacomini, Márcia Sirlene Zardin Graeff, Fernanda Cristina Pimentel Garcia, Daniela Rios, Heitor Marques Honório, Linda Wang
OBJECTIVES: Rhodamine B (RB) is commonly used to evaluate dental polymers, including dental bonding systems (DBS). For reliability assessments, its effect should not only allow visualization of the dentin-polymer interface but also must not interfere with the bonding of the DBS to dentin as measured by the microtensile bond strength and hardness tests. MATERIAL AND METHODS: Flat human dentin surfaces were prepared and randomly distributed (n = 10) into six groups: Adper Scotchbond Multi-Purpose (MP) or Clearfil SE Bond (SE) in concentrations of none/control, 0...
May 17, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29777736/edge-strength-of-cad-cam-materials
#6
Maria Pfeilschifter, Verena Preis, Michael Behr, Martin Rosentritt
OBJECTIVES: To investigate the edge force of CAD/CAM materials as a function of (a) material, (b) thickness, and (c) distance from the margin. METHODS: Materials intended for processing with CAD/CAM were investigated: eight resin composites, one resin-infiltrated ceramic, and a clinically proven lithiumdisilicate ceramic (reference). To measure edge force (that is, load to failure/crack), plates (d = 1 mm) were fixed and loaded with a Vickers diamond indenter (1 mm/min, Zwick 1446) at a distance of 0...
May 16, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29777632/predictor-factors-for-long-term-outcomes-stability-of-coronally-advanced-flap-with-or-without-connective-tissue-graft-in-the-treatment-of-single-maxillary-gingival-recessions-9-years-results-of-a-randomised-controlled-clinical-trial
#7
Giulio Rasperini, Raffaele Acunzo, Gaia Pellegrini, Giorgio Pagni, Maurizio Tonetti, Giovan Paolo Pini Prato, Pierpaolo Cortellini
AIM: To assess the clinical outcomes 9 years after the surgical treatment of single maxillary gingival recessions and identify predictors for long-term gingival margin stability. MATERIALS AND METHODS: Twenty-five gingival recession (Miller Class I and II) were randomly treated with CAF plus CTG or CAF alone. Outcomes included Complete Root Coverage (CRC), Recession Reduction (REC), Keratinized Tissue (KT) gain and dentin hypersensitivity, and were evaluated at 6-month, 1-year and 9-year...
May 19, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29777616/regenerative-endodontics-a-review
#8
REVIEW
S G Kim, M Malek, A Sigurdsson, L M Lin, B Kahler
The European Society of Endodontology and the American Association for Endodontists have released position statements and clinical considerations for regenerative endodontics. There is increasing literature on this field since the initial reports of Iwaya et al. (2001) and Banchs & Trope (2004). Endogenous stem cells from an induced periapical bleeding and scaffolds using blood clot, platelet rich plasma or platelet rich fibrin have been utilized in regenerative endodontics. This approach has been described as a 'paradigm shift" and considered the first treatment option for immature teeth with pulp necrosis...
May 19, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29775860/a-cone-beam-computed-tomography-study-of-the-mesial-cervical-concavity-of-maxillary-first-premolars
#9
Linfeng Fan, Keyong Yuan, Chenguang Niu, Rui Ma, Zhengwei Huang
OBJECTIVE: To investigate the mesial cervical concavity of maxillary first premolars and its relationship with root and canal configuration using cone-beam computed tomography (CBCT). DESIGN: Images of maxillary first premolars (n = 1056) were collected from patients (n = 601) who had undergonein vivo CBCT scanning. The root and canal number and morphology were evaluated. The following measurements of the mesial cervical concavity of the maxillary first premolars were evaluated in section images: dentine thickness (in concavity at the cemento-enamel junction), concavity angle, depression depth (distance from mesial dentinal surface at concavity to mesial proximity), concavity position (distance from mesial dentinal wall at invagination to the top of the mesial marginal ridge)...
May 7, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29775615/extracellular-matrix-protein-dmp1-suppresses-osteogenic-differentiation-of-mesenchymal-stem-cells
#10
Shufan Zhang, Huixuan Wan, Peng Wang, Mengmeng Liu, Gongchen Li, Chunxue Zhang, Yao Sun
Mesenchymal Stem Cells (MSCs) are self-renewing and multipotent stem cells which was investigated for diverse clinical applications. However, complex mechanism of MSCs fate determination is still not fully disclosed. Extracellular matrix (ECM) proteins contribute to maintain MSCs stemness by providing extracellular microenvironment. Increasing evidences show that ECM proteins could also regulate the fate of MSCs directly. Dentin matrix protein 1 (DMP1) is an ECM protein enrich in bone tissue and terminal cells, which well-known in promoting osteoblasts and osteocytes maturation, and facilitate mineralization...
May 15, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29774548/release-of-tgf-%C3%AE-1-into-root-canals-with-various-final-irrigants-in-regenerative-endodontics-an-in-vitro-analysis
#11
Y Chae, M Yang, J R Kim
AIM: To investigate the release of growth factors into the root canal space after various final irrigants during regenerative endodontic procedures. The residual cytotoxic effect of final irrigants on stem cells from the apical papilla (SCAP) was also examined. METHODOLOGY: To measure the release of TGF-β1, root segments (8mm long) were irrigated with 1.5% NaOCl followed by 20 mL of final irrigants; Saline, 17% EDTA, 10% citric acid, 10% or 37% phosphoric acid...
May 17, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29768975/arresting-dentine-caries-with-silver-diamine-fluoride-what-s-behind-it
#12
M L Mei, E C M Lo, C H Chu
Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can simultaneously prevent and arrest coronal and root dentine caries. The profound clinical success of SDF has drawn many clinicians and researchers to study the mechanism of SDF in arresting dentine caries. This critical review discusses how silver and fluoride contribute to caries arrest, in terms of their effects on bacteria as well as on the mineral and organic content of dentine. Silver interacts with bacterial cell membrane and bacterial enzymes, which can inhibit bacterial growth...
May 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29768523/extracellular-calcium-increases-fibroblast-growth-factor-2-gene-expression-via-extracellular-signal-regulated-kinase-1-2-and-protein-kinase-a-signaling-in-mouse-dental-papilla-cells
#13
Sousuke Kanaya, Binlu Xiao, Yukihiko Sakisaka, Mizuki Suto, Kentaro Maruyama, Masahiro Saito, Eiji Nemoto
We previously reported that elevated extracellular calcium (Ca2+) levels increase bone morphogenetic protein 2 expression in human dental pulp (hDP) cells. However, it is unknown whether extracellular Ca2+ affects the expression of other growth factors such as fibroblast growth factor 2 (FGF2). The present study aimed to examine the effect of extracellular Ca2+ on FGF2 gene expression in hDP and immortalized mouse dental papilla (mDP) cells. Cells were stimulated with 10 mM CaCl2 in the presence or absence of cell signaling inhibitors...
May 14, 2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29768091/effect-of-830-nm-diode-laser-irradiation-of-root-canal-on-bond-strength-of-metal-and-fiber-post
#14
Claudia Strefezza, Marcello Magri Amaral, José Quinto, Sheila Cynthia Gouw-Soares, Claudia Bianchi Zamataro, Denise Maria Zezell
OBJECTIVE AND BACKGROUND: The correct selections of the cementing agent, the endodontic post material and placement protocol are critical to provide an increased longevity of the teeth that went through endodontic treatment. The irradiation with diode laser before post cementation, can promote an antimicrobial effect. However, there is a lack of information about the effect of 830 nm diode laser on the post bond strength. This study analyzed the effect of dentin root canal irradiation with high-intensity diode laser, at 830 nm, operating in continuous or pulsed mode, on the retention of metal or fiber posts, cemented with self-etching resinous composite (Panavia F) and zinc phosphate cement (ZnPO4 )...
May 16, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29765903/effect-of-ultrasonic-agitation-on-push-out-bond-strength-and-adaptation-of-root-end-filling-materials
#15
Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marina Angélica Marciano, Jussaro Alves Duque, Samuel Lucas Fernandes, Mariana Bailo Rosseto, Marco Antonio Hungaro Duarte
Objectives: This study evaluated the effect of ultrasonic agitation of mineral trioxide aggregate (MTA), calcium silicate-based cement (CSC), and Sealer 26 (S26) on adaptation at the cement/dentin interface and push-out bond strength. Materials and Methods: Sixty maxillary canines were divided into 6 groups ( n = 10): MTA, S26, and CSC, with or without ultrasonic activation (US). After obturation, the apical portions of the teeth were sectioned, and retrograde cavities were prepared and filled with cement by hand condensation...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29765902/comparison-of-light-transmittance-in-dental-tissues-and-dental-composite-restorations-using-incremental-layering-build-up-with-varying-enamel-resin-layer-thickness
#16
Rodrigo Rocha Maia, Dayane Oliveira, Tracy D'Antonio, Fang Qian, Frederick Skiff
Objectives: To evaluate and compare light-transmittance in dental tissues and dental composite restorations using the incremental double-layer technique with varying layer thickness. Materials and Methods: B1-colored natural teeth slabs were compared to dental restoration build-ups with A2D and B1E-colored nanofilled, supra-nanofilled, microfilled, and microhybrid composites. The enamel layer varied from 0.3, 0.5, or 1.2 mm thick, and the dentin layer was varied to provide a standardized 3...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29765899/the-effect-of-continuous-application-of-mdp-containing-primer-and-luting-resin-cement-on-bond-strength-to-tribochemical-silica-coated-y-tzp
#17
Myung-Jin Lim, Mi-Kyung Yu, Kwang-Won Lee
Objectives: This study investigated the effect of continuous application of 10-methacryloyloxydecyldihydrogen phosphate (MDP)-containing primer and luting resin cement on bond strength to tribochemical silica-coated yttria-stabilized tetragonal zirconia polycrystal (Y-TZP). Materials and Methods: Forty bovine teeth and Y-TZP specimens were prepared. The dentin specimens were embedded in molds, with one side of the dentin exposed for cementation with the zirconia specimen...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29765897/anatomical-analysis-of-the-resected-roots-of-mandibular-first-molars-after-failed-non-surgical-retreatment
#18
Jiyoung Yoon, Byeong-Hoon Cho, Jihyun Bae, Yonghoon Choi
Objectives: Understanding the reason for an unsuccessful non-surgical endodontic treatment outcome, as well as the complex anatomy of the root canal system, is very important. This study examined the cross-sectional root canal structure of mandibular first molars confirmed to have failed non-surgical root canal treatment using digital images obtained during intentional replantation surgery, as well as the causative factors of the failed conventional endodontic treatments. Materials and Methods: This study evaluated 115 mandibular first molars...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29765895/effect-of-smear-layer-deproteinization-on-bonding-of-self-etch-adhesives-to-dentin-a-systematic-review-and-meta-analysis
#19
Khaldoan H Alshaikh, Hamdi H H Hamama, Salah H Mahmoud
Objectives: The aim of this systematic review was to critically analyze previously published studies of the effects of dentin surface pretreatment with deproteinizing agents on the bonding of self-etch (SE) adhesives to dentin. Additionally, a meta-analysis was conducted to quantify the effects of the above-mentioned surface pretreatment methods on the bonding of SE adhesives to dentin. Materials and Methods: An electronic search was performed using the following databases: Scopus, PubMed and ScienceDirect...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29765331/high-ph-sensitive-store-operated-ca-2-entry-mediated-by-ca-2-release-activated-ca-2-channels-in-rat-odontoblasts
#20
Maki Kimura, Koichi Nishi, Asuka Higashikawa, Sadao Ohyama, Kaoru Sakurai, Masakazu Tazaki, Yoshiyuki Shibukawa
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+ ]i ) in odontoblasts, which is mediated by Ca2+ release from intracellular Ca2+ stores and/or Ca2+ influx from the extracellular medium. In a previous study, we demonstrated that the depletion of Ca2+ stores in odontoblasts activated store-operated Ca2+ entry (SOCE), a Ca2+ influx pathway...
2018: Frontiers in Physiology
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