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https://www.readbyqxmd.com/read/29453023/implications-of-altered-maternal-cytokine-concentrations-on-infant-outcomes-in-children-with-prenatal-alcohol-exposure
#1
K D Sowell, J Y Uriu-Adams, J Van de Water, C D Chambers, C D Coles, J A Kable, L Yevtushok, N Zymak-Zakutnya, W Wertelecki, C L Keen
Excessive alcohol consumption has been shown to increase serum plasma levels of numerous immune cytokines. Maternal immune activation and elevated cytokines have been implicated in certain neurological disorders (e.g., autism and schizophrenia) in the offspring. We investigated the hypothesis that elevated cytokines during pregnancy are a risk factor in women who gave birth to a child with Fetal Alcohol Spectrum Disorder (FASD) or a child with neurobehavioral impairment, regardless of prenatal alcohol exposure...
August 12, 2017: Alcohol
https://www.readbyqxmd.com/read/29436350/a-longitudinal-study-of-household-water-sanitation-and-hygiene-characteristics-and-environmental-enteropathy-markers-in-children-less-than-24-months-in-iquitos-peru
#2
Natalie G Exum, Gwenyth O Lee, Maribel Paredes Olórtegui, Pablo Peñataro Yori, Mery Siguas Salas, Dixner Rengifo Trigoso, Josh Colston, Kellogg J Schwab, Benjamin J J McCormick, Margaret N Kosek
Poor child gut health, resulting from a lack of access to an improved toilet or clean water, has been proposed as a biological mechanism underlying child stunting and oral vaccine failure. Characteristics related to household sanitation, water use, and hygiene were measured among a birth cohort of 270 children from peri-urban Iquitos Peru. These children had monthly stool samples and urine samples at four time points and serum samples at (2-4) time points analyzed for biomarkers related to intestinal inflammation and permeability...
February 12, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29433021/residential-green-space-and-birth-outcomes-in-a-coastal-setting
#3
Kimberly B Glazer, Melissa N Eliot, Valery A Danilack, Lynn Carlson, Maureen G Phipps, Payam Dadvand, David A Savitz, Gregory A Wellenius
BACKGROUND: Residential green space may improve birth outcomes, with prior studies reporting higher birthweight among infants of women living in greener areas. However, results from studies evaluating associations between green space and preterm birth have been mixed. Further, the potential influence of residential proximity to water, or 'blue space', on health has not previously been evaluated. OBJECTIVES: To evaluate associations between green and blue space and birth outcomes in a coastal area of the northeastern United States...
February 9, 2018: Environmental Research
https://www.readbyqxmd.com/read/29430738/neonatal-adoptive-transfer-of-lymphocytes-rescues-social-behavior-during-adolescence-in-immune-deficient-mice
#4
Sarah M Clark, Chloe N Vaughn, Jennifer A Soroka, Xin Li, Leonardo H Tonelli
Accumulating evidence has shown that lymphocytes modulate behavior and cognition by direct interactions with the central nervous system. Studies have shown that reconstitution by adoptive transfer of lymphocytes from wild type into immune deficient mice restores a number of neurobehavioral deficits observed in these models. Moreover, it has been shown that these effects are mostly mediated by T lymphocytes. Studies of adoptive transfer thus far have employed adult mice, but whether lymphocytes may also modulate behavior during development remains unknown...
February 11, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29430296/ramadan-during-pregnancy-and-birth-weight-of-newborns
#5
Ary I Savitri, Dwirani Amelia, Rebecca C Painter, Mohammad Baharuddin, Tessa J Roseboom, Diederick E Grobbee, Cuno S P M Uiterwaal
Previous studies suggest that Ramadan exposure during pregnancy might affect the health of women and their babies, particularly through the effect of fasting. This study aimed to evaluate the association between Ramadan exposure and fasting during pregnancy on the birth weight of newborns. This study concerned 1351 pregnant women from a prospective cohort in Jakarta, Indonesia. Ramadan exposure was based on the actual overlap between Ramadan and pregnancy. Women's fasting behaviour was recorded among 139 women who came for antenatal care between 10 July 2013 and 7 August 2013, and those who had fasted for at least 1 d (n 110) were classified as exposed to Ramadan fasting...
2018: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29421483/effect-of-suckler-cow-vaccination-against-glycoprotein-e-ge-negative-bovine-herpesvirus-type-1-bohv-1-on-passive-immunity-and-physiological-response-to-subsequent-bovine-respiratory-disease-vaccination-of-their-progeny
#6
Bernadette Earley, Katie Tiernan, Catherine Duffy, Amanda Dunn, Sinead Waters, Steven Morrison, Mark McGee
The study objectives were: 1) to characterise the development of immunocompetence in beef suckler calves from birth to three months of age, and 2) to trace glycoprotein E (gE)-negative bovine herpesvirus type 1 (BoHV-1) antibodies from dam to calf and subsequent vaccination against pneumonia. Thirty multiparous beef suckler, spring-calving cows, consisting of two genotypes were involved; Limousin×Friesian (LF) and Charolais×Limousin (CL). Cows were immunised against the inactivated antigen strain of BoHV-1 (gE- (IBR marker vaccine) at day -84 and received a booster at day -56 relative to the expected calving date (d 0)...
January 10, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29421409/prenatal-exposure-to-glycol-ethers-and-sex-steroid-hormones-at-birth
#7
Charline Warembourg, Anne-Claire Binter, Frank Giton, Jean Fiet, Laurence Labat, Christine Monfort, Cécile Chevrier, Luc Multigner, Sylvaine Cordier, Ronan Garlantézec
BACKGROUND: Glycol ethers (GEs) are oxygenated solvents widely found in occupational and consumer water-based products. Some of them are well-known reproductive and developmental toxicants. OBJECTIVES: To study the variations in circulating sex steroid hormones, measured in cord blood, according to biomarkers of prenatal GE exposure. METHODS: The study population comes from the PELAGIE mother-child cohort, which enrolled pregnant women from Brittany (France, 2002-2006)...
January 31, 2018: Environment International
https://www.readbyqxmd.com/read/29410109/in-vivo-raman-spectroscopy-for-biochemical-monitoring-of-the-cervix-throughout-pregnancy
#8
Christine M O'Brien, Elizabeth Vargis, Amy Rudin, James C Slaughter, Giju Thomas, J Michael Newton, Jeff Reese, Kelly A Bennett, Anita Mahadevan-Jansen
BACKGROUND: The cervix must undergo significant biochemical remodeling to allow for successful parturition. This process is not fully understood, especially in instances of spontaneous preterm birth. In vivo Raman spectroscopy is an optical technique that can be used to investigate the biochemical composition of tissue longitudinally and non-invasively in humans, and has been utilized to measure physiology and disease states in a variety of medical applications. OBJECTIVE: The purpose of this study is to measure in vivo Raman spectra of the cervix throughout pregnancy in women, and to identify biochemical markers that change with the preparation for delivery and post-partum repair...
January 31, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29408268/the-development-of-progesterone-loaded-nanofibers-using-pressurized-gyration-a-novel-approach-to-vaginal-delivery-for-the-prevention-of-pre-term-birth
#9
Francis Brako, Bahijja Tolulope Raimi-Abraham, Suntharavathanan Mahalingam, Duncan Q M Craig, Mohan Edirisinghe
Recent evidence has continued to support the applicability of progesterone in preventing preterm birth, hence the development of an appropriate vaginal delivery system for this drug would be of considerable interest. Here, we describe the development of progesterone-loaded bioadhesive nanofibers using pressurized gyration for potential incorporation into a vaginal insert, with a particular view to addressing the challenges of incorporating a poorly water-soluble drug into a hydrophilic nanofiber carrier. Polyethylene oxide and carboxymethyl cellulose were chosen as polymers to develop the carrier systems, based on previous evidence of their yielding mucoadhesive nanofibers using the pressurized gyration technique...
February 2, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29400265/socio-economic-environmental-and-nutritional-characteristics-of-urban-and-rural-south-indian-women-in-early-pregnancy-findings-from-the-south-asian-birth-cohort-start
#10
Pratibha Dwarkanath, Anil Vasudevan, Tinku Thomas, Sonia S Anand, Dipika Desai, Milan Gupta, Gladys Menezes, Anura V Kurpad, Krishnamachari Srinivasan
OBJECTIVE: High frequency of low birth weight (LBW) is observed in rural compared with urban Indian women. Since maternal BMI is known to be associated with pregnancy outcomes, the present study aimed to investigate factors associated with BMI in early pregnancy of urban and rural South Indian women. DESIGN: Prospective observational cohort. SETTING: A hospital-based study conducted at an urban and a rural health centre in Karnataka State...
February 5, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29398924/implementing-a-geographical-information-system-to-assess-endemic-fluoride-areas-in-lamphun-thailand
#11
Nonthaphat Theerawasttanasiri, Surasak Taneepanichskul, Wichain Pingchai, Yuwaree Nimchareon, Sangworn Sriwichai
Introduction: Many studies have shown that fluoride can cross the placenta and that exposure to high fluoride during pregnancy may result in premature birth and/or a low birth weight. Lamphun is one of six provinces in Thailand where natural water fluoride (WF) concentrations >10.0 mg/L were found, and it was also found that >50% of households used water with high fluoride levels. Nevertheless, geographical information system (GIS) and maps of endemic fluoride areas are lacking...
2018: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/29385626/developmental-thyroid-hormone-insufficiency-induces-a-cortical-brain-malformation-and-learning-impairments-a-cross-fostering-study
#12
K O'Shaughnessy, P Kosian, J Ford, W Oshiro, S Degitz, M E Gilbert
Thyroid hormones (TH) are essential for brain development, but there exists few rodent models that link TH insufficiency to apical neurodevelopmental endpoints. We have previously described a structural anomaly, a heterotopia, in the brains of rats treated in utero with propylthiouracil (PTU). However, how the timing of an exposure relates to this birth defect is unknown. This study seeks to understand how various temporal treatments of the mother relates to TH insufficiency and adverse neurodevelopment of the offspring...
January 27, 2018: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29382224/determinants-of-stunting-wasting-and-anemia-in-guinean-preschool-age-children-an-analysis-of-dhs-data-from-1999-2005-and-2012
#13
Bradley A Woodruff, James P Wirth, Ismael Ngnie-Teta, Jean Max Beaulière, Daffe Mamady, Mohamed Ag Ayoya, Fabian Rohner
Wasting, stunting, and anemia are persistent and important forms of malnutrition in preschool-age children in the less developed world, in particular the Republic of Guinea, which was the site of a large outbreak of Ebola virus disease in 2014 to 2015. We analyzed data from 3 Demographic and Health Surveys done in Guinea in 1999, 2005, and 2012 to identify possible determinants of wasting, stunting, and anemia. All analyses, both bivariate and multivariate, were carried out separately for each of 3 age groups: less than 6 months, 6 to 23 months, and 24 to 59 months...
January 1, 2018: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/29373601/transcriptional-changes-detected-in-fecal-rna-of-neonatal-dairy-calves-undergoing-a-mild-diarrhea-are-associated-with-inflammatory-biomarkers
#14
Fernanda Rosa, Sebastiano Busato, Fatima C Avaroma, Kali Linville, Erminio Trevisi, Johan S Osorio, Massimo Bionaz
After birth, a newborn calf has to adapt to an extrauterine life characterized by several physiological changes. In particular, maturation of the gastrointestinal tract in a new environment loaded with potential pathogens, which can predispose neonatal calves to develop diarrhea, and is a major cause of morbidity and mortality during the first 4 wks of life. We aimed to investigate the inflammatory adaptations at a transcriptomic level in the gastrointestinal (GI) tract to a mild diarrhea in neonatal dairy calves using RNA isolated from fresh fecal samples...
2018: PloS One
https://www.readbyqxmd.com/read/29370271/sero-prevalence-and-risk-factors-for-hepatitis-e-virus-infection-among-pregnant-women-in-the-cape-coast-metropolis-ghana
#15
Dorcas Obiri-Yeboah, Yaw Asante Awuku, Joseph Adu, Faustina Pappoe, Evans Obboh, Paul Nsiah, Daniel Amoako-Sakyi, Jacques Simpore
BACKGROUND: Hepatitis E virus is an emerging infection in Africa with poor maternal and foetal outcomes. There is scanty data on the sero-prevalence of HEV infection among pregnant women in Ghana. This study highlighted the prevalence and risk factors associated with HEV infection among pregnant women in Cape Coast Metropolis, Central Region of Ghana. METHODS: A multicenter (3 selected sites) analytical cross sectional study involving 398 pregnant women in the Cape Coast metropolis was conducted...
2018: PloS One
https://www.readbyqxmd.com/read/29353689/neonatal-outcomes-with-water-birth-a-systematic-review-and-meta-analysis
#16
REVIEW
Jennifer Vanderlaan, Priscilla J Hall, MaryJane Lewitt
No abstract text is available yet for this article.
December 26, 2017: Midwifery
https://www.readbyqxmd.com/read/29349652/social-factors-associated-with-non-initiation-and-cessation-of-predominant-breastfeeding-in-a-mother-child-cohort-in-spain
#17
Maria Villar, Loreto Santa-Marina, Mario Murcia, Pilar Amiano, Silvia Gimeno, Ferran Ballester, Jordi Julvez, Dora Romaguera, Ana Fernández-Somoano, Adonina Tardón, Jesús Ibarluzea
Objective The aim of the study was to identify factors associated with non-initiation and cessation of predominant breastfeeding (PBF) in a mother-child cohort from Spain. Materials and Methods The analysis included 2195 mother-infant from birth to 14 months post- delivery recruited between 2004 and 2008. Maternal characteristics were collected during the pregnancy. Lactation data were obtained at 6 and 14 months after delivery. PBF was defined as intake of breast milk plus liquids like juices or water. The PBF cessation was calculated using the date that women started PBF and the date that she reported to start giving infant formula and/or food...
January 18, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29347350/birth-of-a-subaqueous-barchan-dune
#18
Carlos A Alvarez, Erick M Franklin
Barchan dunes are crescentic shape dunes with horns pointing downstream. The present paper reports the formation of subaqueous barchan dunes from initially conical heaps in a rectangular channel. Because the most unique feature of a barchan dune is its horns, we associate the time scale for the appearance of horns to the formation of a barchan dune. A granular heap initially conical was placed on the bottom wall of a closed conduit and it was entrained by a water flow in turbulent regime. After a certain time, horns appear and grow, until an equilibrium length is reached...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29344940/obstetric-and-neonatal-outcomes-for-women-intending-to-use-immersion-in-water-for-labour-and-birth-in-western-australia-2015-2016-a-retrospective-audit-of-clinical-outcomes
#19
Lucy Lewis, Yvonne L Hauck, Janice Butt, Janet Hornbuckle
BACKGROUND: Research supports water immersion for labour if women are healthy, with no obstetric or medical risk factors. AIMS: To evaluate the obstetric and neonatal outcomes of women intending to use immersion in water for labour or birth. METHODS: Retrospective audit of clinical outcomes for women intending to labour or birth in water conducted between July 2015 and June 2016, at a tertiary maternity hospital in Western Australia. Obstetric and neonatal data were collected from medical records...
January 17, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29325538/influence-of-isoflurane-exposure-in-pregnant-rats-on-the-learning-and-memory-of-offsprings
#20
Wei Huang, Yunxia Dong, Guangyi Zhao, Yuan Wang, Jingjing Jiang, Ping Zhao
BACKGROUND: About 2% of pregnant women receive non-obstetric surgery under general anesthesia each year. During pregnancy, general anesthetics may affect brain development of the fetus. This study aimed to investigate safe dosage range of isoflurane. METHODS: Forty-eight SpragueDawley (SD) pregnant rats were randomly divided into 3 groups and inhaled 1.3% isoflurane (the Iso1 group), 2.0% isoflurane (the Iso2 group) and 50% O2 alone (the control group) for 3 h, respectively...
January 11, 2018: BMC Anesthesiology
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