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Dendrobium

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https://www.readbyqxmd.com/read/28197691/the-medicinal-and-pharmaceutical-importance-of-dendrobium-species
#1
REVIEW
Jaime A Teixeira da Silva, Tzi Bun Ng
Plants of the Dendrobium genus, one of the largest in the Orchidaceae, manifest a diversity of medicinal effects encompassing antiangiogenic, immunomodulating, antidiabetic, cataractogenesis-inhibiting, neuroprotective, hepatoprotective, anti-inflammatory, antiplatelet aggregation, antifungal, antibacterial, antiherpetic, antimalarial, aquaporin-5 stimulating, and hemagglutininating activities and also exert beneficial actions on colonic health and alleviate symptoms of hyperthyroidism. The active principles include a wide range of proteinaceous and non-proteinaceous molecules...
February 14, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28195549/dendrobium-chrysanthum-ethanolic-extract-induces-apoptosis-via-p53-up-regulation-in-hela-cells-and-inhibits-tumor-progression-in-mice
#2
Ritika Prasad, Nishant Kumar Rana, Biplob Koch
Background Dendrobium is one of the diverse genus of orchid plants. It possesses a number of pharmacological activities and has long been used in traditional system of medicine. The goal of this study was to investigate the apoptosis inducing property of the ethanolic extract from the leaves of Dendrobium chrysanthum, a species of Dendrobium whose anticancer role has not been ascertained yet. Methods To evaluate the anticancer activity of the ethanolic extract of D. chrysanthum in vitro in HeLa (human cervical cancer) cells, cytotoxic activity, generation of reactive oxygen species (ROS), induction of apoptosis and effect on cell cycle were determined...
February 14, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28182623/evaluation-of-dna-barcodes-in-codonopsis-campanulaceae-and-in-some-large-angiosperm-plant-genera
#3
De-Yi Wang, Qiang Wang, Ying-Li Wang, Xiao-Guo Xiang, Lu-Qi Huang, Xiao-Hua Jin
DNA barcoding is expected to be one of the most promising tools in biological taxonomy. However, there have been no agreements on which core barcode should be used in plants, especially in species-rich genera with wide geographical distributions. To evaluate their discriminatory power in large genera, four of the most widely used DNA barcodes, including three plastid regions (matK, rbcL, trnH-psbA) and nuclear internal transcribed spacer (nrITS), were tested in seven species-rich genera (Ficus, Pedicularis, Rhodiola, Rhododendron,Viburnum, Dendrobium and Lysimachia) and a moderate size genus, Codonopsis...
2017: PloS One
https://www.readbyqxmd.com/read/28176760/dogmp1-from-dendrobium-officinale-contributes-to-mannose-content-of-water-soluble-polysaccharides-and-plays-a-role-in-salt-stress-response
#4
Chunmei He, Zhenming Yu, Jaime A Teixeira da Silva, Jianxia Zhang, Xuncheng Liu, Xiaojuan Wang, Xinhua Zhang, Songjun Zeng, Kunlin Wu, Jianwen Tan, Guohua Ma, Jianping Luo, Jun Duan
GDP-mannose pyrophosphorylase (GMP) catalyzed the formation of GDP-mannose, which serves as a donor for the biosynthesis of mannose-containing polysaccharides. In this study, three GMP genes from Dendrobium officinale (i.e., DoGMPs) were cloned and analyzed. The putative 1000 bp upstream regulatory region of these DoGMPs was isolated and cis-elements were identified, which indicates their possible role in responses to abiotic stresses. The DoGMP1 protein was shown to be localized in the cytoplasm. To further study the function of the DoGMP1 gene, 35S:DoGMP1 transgenic A...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28146409/granularity-and-laxative-effect-of-ultrafine-powder-of-dendrobium-officinale
#5
DanDan Luo, Chao Qu, ZhenBiao Zhang, JianHui Xie, LieQiang Xu, HongMei Yang, CaiLan Li, GuoSheng Lin, HongFeng Wang, ZiRen Su
Constipation is a common disorder that is a significant source of morbidity among people around the world ranging from 2% to 28%. Dendrobium officinale Kimura et Migo is a traditional herbal medicine and health food used for tonicity of the stomach and promotion of body fluid production in China. This study aimed to prepare the ultrafine powder of Dendrobium officinale (UDO) and investigate its laxative effect and potential mechanism in mice with diphenoxylate-induced constipation. Results indicated that the mean diameter (d50) of UDO obtained by ball milling was 6...
February 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28138710/moscatilin-induces-apoptosis-of-pancreatic-cancer-cells-via-reactive-oxygen-species-and-the-jnk-sapk-pathway
#6
Lei Zhang, Yuan Fang, Xue-Feng Xu, Da-Yong Jin
Moscatilin is a bibenzyl derivative extracted from the Dendrobium aurantiacum var. denneanum, which has traditionally been used as an immunomodulatory treatment in China. The present study was designed to determine whether moscatilin is a pro‑apoptotic agent in pancreatic cancer, and to elucidate the underlying mechanisms. The apoptotic and anti‑proliferative effects of moscatilin on pancreatic cancer cells were determined in vitro using biochemical assays, such as the MTT assay, colony formation assay, Hoechst staining and DNA fragmentation assay, and in vivo using Panc‑1 pancreatic cancer xenografts...
January 25, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28131062/anthocyanin-biosynthesis-regulation-of-dhmyb2-and-dhbhlh1-in-dendrobium-hybrids-petals
#7
Chonghui Li, Jian Qiu, Ling Ding, Mingzhong Huang, Surong Huang, Guangsui Yang, Junmei Yin
Dendrobium hybrids orchid are popular throughout the world. They have various floral color and pigmentation patterns that are mainly caused by anthocyanins. It is well established that anthocyanin biosynthesis is regulated by the interplay between MYB and bHLH transcription factors (TF) in most plants. In this study, we identified one R2R3-MYB gene, DhMYB2, and one bHLH gene, DhbHLH1, from a Dendrobium hybrid. Their expression profiles were related to anthocyanin pigmentation in Dendrobium petals. Transient over-expression of these two TF genes showed that both DhMYB2 and DhbHLH1 resulted in anthocyanin production in white petals...
March 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28129624/erianin-inhibits-indoleamine-2-3-dioxygenase-induced-tumor-angiogenesis
#8
Chang Su, Peng Zhang, Jianwen Liu, Yiou Cao
Tumor angiogenesis is the key process in tumor growth and metastasis, and transfers essential nutrients for solid tumor. Inhibition of tumor angiogenesis has been recognized as a more effective anti-cancer strategy for NSCLC and has acquired certain therapeutic effects. IDO has non-immune functions including regulating tumor angiogenesis and IDO dysregulation in cancer pathogenesis has been valued. Erianin is a natural product isolated from Dendrobium chrysotoxum Lindl. The antitumor activity of erianin in many kinds of cancers had been demonstrated in previous studies...
January 24, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28106808/anti-fatigue-effects-of-the-unique-polysaccharide-marker-of-dendrobium-officinale-on-balb-c-mice
#9
Wei Wei, Zhi-Peng Li, Tong Zhu, Hau-Yee Fung, Tin-Long Wong, Xin Wen, Dik-Lung Ma, Chung-Hang Leung, Quan-Bin Han
Dendrobium officinale extract shows potent anti-fatigue effects; however, the active substance responsible for these effects remains undetermined. A glucomannan with a huge molecular size of 730 kDa, called DOP, was identified as the unique authentication marker of this expensive herb. DOP exhibited immunomodulating effects on macrophages and lymphocytes in our previous study. Clinical reports also showed that people with fatigue syndrome have a disturbed immune system. Because DOP is the unique and dominant component of D...
January 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28104409/gigantol-from-dendrobium-chrysotoxum-lindl-binds-and-inhibits-aldose-reductase-gene-to-exert-its-anti-cataract-activity-an-in-vitro-mechanistic-study
#10
Jie Wu, Xue Li, Wencheng Wan, Qiaohong Yang, Weifeng Ma, Dan Chen, Jiangmiao Hu, C-Y Oliver Chen, Xiaoyong Wei
ETHNOPHARMACOLOGICAL RELEVANCE: Dendrobium. chrysotoxum Lindl is a commonly used species of medicinal Dendrobium which belongs to the family of Orchidaceae, locally known as "Shihu" or "Huangcao". D. chrysotoxum Lindl is widely known for medicinal values in traditional Chinese medicine as it possesses anti-inflammatory, anti-hyperglycemic induction, antitumor and antioxidant properties. STUDY AIM: To characterize the interaction between gigantol extracted from D...
January 16, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28004781/functional-insights-into-the-late-embryogenesis-abundant-lea-protein-family-from-dendrobium-officinale-orchidaceae-using-an-escherichia-coli-system
#11
Hong Ling, Xu Zeng, Shunxing Guo
Late embryogenesis abundant (LEA) proteins, a diverse family, accumulate during seed desiccation in the later stages of embryogenesis. LEA proteins are associated with tolerance to abiotic stresses, such as drought, salinity and high or cold temperature. Here, we report the first comprehensive survey of the LEA gene family in Dendrobium officinale, an important and widely grown medicinal orchid in China. Based on phylogenetic relationships with the complete set of Arabidopsis and Oryza LEA proteins, 17 genes encoding D...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27994964/dendrobium-alkaloids-prevent-a%C3%AE-25-35-induced-neuronal-and-synaptic-loss-via-promoting-neurotrophic-factors-expression-in-mice
#12
Jing Nie, Yong Tian, Yu Zhang, Yan-Liu Lu, Li-Sheng Li, Jing-Shan Shi
BACKGROUND: Neuronal and synaptic loss is the most important risk factor for cognitive impairment. Inhibiting neuronal apoptosis and preventing synaptic loss are promising therapeutic approaches for Alzheimer's disease (AD). In this study, we investigate the protective effects of Dendrobium alkaloids (DNLA), a Chinese medicinal herb extract, on β-amyloid peptide segment 25-35 (Aβ25-35)-induced neuron and synaptic loss in mice. METHOD: Aβ25-35(10 µg) was injected into the bilateral ventricles of male mice followed by an oral administration of DNLA (40 mg/kg) for 19 days...
2016: PeerJ
https://www.readbyqxmd.com/read/27987037/molecular-cloning-and-functional-analysis-of-the-phosphomannomutase-pmm-gene-from-dendrobium-officinale-and-evidence-for-the-involvement-of-an-abiotic-stress-response-during-germination
#13
Chunmei He, Songjun Zeng, Jaime A Teixeira da Silva, Zhenming Yu, Jianwen Tan, Jun Duan
Phosphomannomutase (PMM, EC 5.4.2.8) catalyzes the interconversion of mannose-6-phosphate to mannose-1-phosphate, the precursor for the synthesis of GDP-mannose. In this study, the complementary DNA (cDNA) of the Phosphomannomutase (PMM) gene was initially cloned from Dendrobium officinale by RACE method. Transient transform result showed that the DoPMM protein was localized in the cytoplasm. The DoPMM gene was highly expressed in the stems of D. officinale both in vegetative and reproductive developmental stages...
December 16, 2016: Protoplasma
https://www.readbyqxmd.com/read/27975783/structure-characterization-and-immunomodulating-effects-of-polysaccharides-isolated-from-dendrobium-officinale
#14
W Wei, L Feng, S P Nie, Q B Han
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27959444/gigantol-attenuates-the-proliferation-of-human-liver-cancer-hepg2-cells-through-the-pi3k-akt-nf-%C3%AE%C2%BAb-signaling-pathway
#15
Huanhuan Chen, Yuechun Huang, Junbin Huang, Lizhen Lin, Gang Wei
Gigantol is a phenolic substance extracted from plants in the genus Dendrobium and used in traditional Chinese medicine. In the present study, we aimed to investigate the growth inhibition and apoptotic effects of gigantol on human liver cancer cells through the PI3K/Akt/NF-κB signaling pathway. HepG2 cells were treated with different concentrations of gigantol (0-150 µM) for 12, 24 and 48 h. It was found that gigantol significantly inhibited the proliferation and induced apoptosis of the HepG2 cells...
February 2017: Oncology Reports
https://www.readbyqxmd.com/read/27931140/phylogeography-of-the-endangered-orchid-dendrobium-moniliforme-in-east-asia-inferred-from-chloroplast-dna-sequences
#16
Meirong Ye, Wei Liu, Qingyun Xue, Beiwei Hou, Jing Luo, Xiaoyu Ding
The aim of the current study was to elucidate the phylogeographic history of Dendrobium moniliforme, an endangered orchid species, based on two chloroplast DNA (cpDNA) markers (trnC-petN and trnE-trnT). One hundred and thirty-five samples were collected from 18 natural populations of D. moniliforme covering the entire range of the Sino-Japanese Floristic Region (SJFR) of East Asia. A total of 35 distinct cpDNA haplotypes were identified in these populations, of which 23 haplotypes were each present in only one sample and thus restricted to a single population...
December 8, 2016: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/27931121/a-new-phenolic-glycoside-from-the-stem-of-dendrobium-nobile
#17
Xue-Ming Zhou, Cai-Juan Zheng, Jia-Ting Wu, Guang-Ying Chen, Bin Zhang, Chong-Ge Sun
A new phenolic glycoside dendroside (1), together with seven known compounds (2-8) were isolated from the stems of Dendrobium nobile. The structures of these compounds were elucidated using comprehensive spectroscopic methods. The inhibitory activities of all compounds against three cancer cell lines HeLa, MCF-7 and A549 were evaluated.
May 2017: Natural Product Research
https://www.readbyqxmd.com/read/27925008/ros-induced-oxidative-stress-in-nobile-type-dendrobium-protocorm-like-bodies-plbs-during-vitrification
#18
M Jia, W Di, Yan Liu, Yin Shi, Y Xie
BACKGROUND: Oxidative stress involved in cryopreservation protocols may be responsible for the poor survival of tissues after cryopreservation. OBJECTIVE: In the current study, we aimed to clarify the role of oxidative stress and its relationship with survival rate during cryopreservation of PLBs from nobile-type Dendrobium. MATERIALS AND METHODS: ROS, antioxidants and oxidative products and the survival rate in PLBs from Dendrobium Hamanal Lake Dream were determined during vitrification...
July 2016: Cryo Letters
https://www.readbyqxmd.com/read/27877182/insights-from-the-cold-transcriptome-and-metabolome-of-dendrobium-officinale-global-reprogramming-of-metabolic-and-gene-regulation-networks-during-cold-acclimation
#19
Zhi-Gang Wu, Wu Jiang, Song-Lin Chen, Nitin Mantri, Zheng-Ming Tao, Cheng-Xi Jiang
Plant cold acclimation (CA) is a genetically complex phenomenon involving gene regulation and expression. Little is known about the cascading pattern of gene regulatroy network and the link between genes and metabolites during CA. Dendrobium officinale (DOKM) is an important medicinal and ornamental plant and hypersensitive to low temperature. Here, we used the large scale metabolomic and transcriptomic technologies to reveal the response to CA in DOKM seedlings based on the physiological profile analyses. Lowering temperature from 4 to -2°C resulted in significant increase (P < 0...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27837285/dendrobium-protoplast-co-culture-promotes-phytochemical-assemblage-in-vitro
#20
Abitha Thomas, Ipsita Pujari, Vasudeep Shetty, Manjunath B Joshi, Padmalatha S Rai, Kapaettu Satyamoorthy, Vidhu Sankar Babu
The present study is intended to analyze the occurrence of potent, low produce, naturally occurring stilbenes in protoplasts of wild species and hybrids of Dendrobium. The wild species selected for the study was Dendrobium ovatum, endemic to Western Ghats of India. Protoplasts were isolated from leaves and tepal tissues of all the species and were cultured purely to generate homofusants and cross-cultured to raise heterofusants. Phytochemical composition of protoplast culture with atypical and pure microcolonies was performed using mass spectrometry...
November 11, 2016: Protoplasma
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