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https://www.readbyqxmd.com/read/28206674/effects-of-spinal-cord-stimulation-on-cardiac-sympathetic-nerve-activity-in-patients-with-heart-failure
#1
Jan Naar, Deborah Jaye, Cecilia Linde, Petr Neužil, Petr Doškář, Filip Málek, Frieder Braunschweig, Lars H Lund, Lars Mortensen, Bengt Linderoth, Göran Lind, Dianna Bone, Arthur J Scholte, Fred Kueffer, Jodi Koehler, Kambiz Shahgaldi, Otto Lang, Marcus Ståhlberg
BACKGROUND: Spinal cord stimulation (SCS) reduces sympathetic activity in animal models of heart failure with reduced ejection fraction (HF) but limited data exist of SCS in patients with HF. The aim of the present study was to test the primary hypothesis that SCS reduces cardiac sympathetic nerve activity in HF patients. Secondary hypotheses were that SCS improves left ventricular function and dimension, exercise capacity and clinical variables relevant to HF. METHODS: HF patients with a SCS device previously participating in the DEFEAT-HF trial were included in this crossover study with 6-week intervention periods (SCS-ON and SCS-OFF)...
February 16, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28190926/malignant-mast-cell-tumor-of-the-thymus-in-an-royal-college-of-surgeons-rcs-rat
#2
Yui Terayama, Tetsuro Matsuura, Kiyokazu Ozaki
A 152-week-old male Royal College of Surgeons (RCS) rat kept as a non-treated animal in a long-term animal study presented with a soft mass in the anterior mediastinum, which adhered to the pleura of the lung. Histopathologically, the mass mainly consisted of round to short spindle-shaped tumor cells that had infiltrated through the hyperplastic thymic tissue. The tumor cells were arranged in loose to dense sheets. Nuclei were moderate in size and round to spindle-shaped, with small nucleoli. Almost all tumor cells exhibited abundant eosinophilic cytoplasm, including eosinophilic granules of a range of sizes...
January 2017: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/28187489/-dentogene-focus-as-a-rare-cause-of-necrotizing-fasciitis
#3
Christopher Kloth, Sebastian Hoefert, Till Fischborn, Christina Schraml
History and clinical findings We elaborate the case of a 72-year-old patient who presented with a painful swelling of the lower jaw in the emergency unit. Investigations and diagnosis In the clinical examination and the CT scan, a widespread cervical emphysema was found which raised suspicion for the presence of a necrotizing fasciitis of the head and neck due to aerogenic infection. Close spatial vicinity to the teeth of the left upper and lower jaw was present, so that the necrotizing fasciitis was assumed to be odontogenic...
February 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28178581/inflammatory-myofibroblastic-tumor-of-mediastinum-with-esophageal-and-bronchial-invasion-a-case-report-and-literature-review
#4
Vineet Gorolay, Bronwyn Jones
We report a case of inflammatory myofibroblastic tumor of the posterior mediastinum and describe radiological features demonstrated on fluoro-esophagogram, computed tomography and positron-emission tomography. Fluoroscopic video-esophagoscopy was remarkable for an unusual polypoid lesion associated with partial esophageal obstruction and features of secondary achalasia. CT examination demonstrated coarse calcifications and air pockets, while unusual clinical features included an intraluminal esophageal lesion and local recurrence with endobronchial lesion...
September 28, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/28174490/clinical-value-of-contrast-enhanced-ultrasound-in-improving-diagnostic-accuracy-rate-of-transthoracic-biopsy-of-anterior-medial-mediastinal-lesions
#5
Jingjing Fu, Wei Yang, Song Wang, Jing Bai, Hao Wu, Haiyue Wang, Kun Yan, Minhua Chen
OBJECTIVE: To evaluate the clinical value of contrast-enhanced ultrasound (CEUS) in transthoracic biopsy of anterior-medial mediastinal lesions. METHODS: A total of 123 patients with anterior or middle mediastinum lesions required ultrasound guided transthoracic biopsy for pathological diagnosis. Among them, 72 patients received CEUS examinations before biopsy. After CEUS, 8 patients were excluded from biopsy and the rest 64 patients underwent biopsy (CEUS group)...
December 2016: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28174403/-two-surgical-cases-of-m%C3%A3-llerian-cyst-arising-from-the-posterior-mediastinum
#6
Yuki Oshima, Yoshiteru Kidokoro, Kunio Araki, Yasuaki Kubouchi, Youhei Yurugi, Makoto Wakahara, Yuki Matsuoka, Ken Miwa, Yuji Taniguchi, Hiroshige Nakamura
We experienced 2 cases of Müllerian cyst. Case 1 was a 48-year-old woman with a paravertebral cystic tumor. The tumor grew from 23 to 31 mm in diameter for the 3 years. She underwent video-assisted thoracic surgery(VATS) for the excision of the tumor. Case 2 was a 40-year-old woman with a paravertebral cystic tumor, who underwent VATS. The Histological finding showed that the tumors of both cases were the cysts lined by non-stratified cuboidal to columnar epithelium and epithelial cells were positive in the nucleus with estrogen receptor immunohistochemically...
February 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28166957/chemical-castration-in-cattle-with-intratesticular-injection-of-sodium-chloride-effects-on-stress-and-inflammatory-markers
#7
Fernando C Oliveira, Carlos E R Ferreira, Cristina S Haas, Leonardo G Oliveira, Rafael G Mondadori, Augusto Schneider, Monique T Rovani, Paulo B D Gonçalves, Arnaldo D Vieira, Bernardo G Gasperin, Thomaz Lucia
Intratesticular injection (ITI) of sodium chloride (NaCl) is efficient for chemical castration of young calves, but its effects on calves welfare are unknown. Two experiments were conducted to evaluate the effects of ITI of 20% NaCl on stress and inflammatory markers in calves less than 20 days old and to assess the efficiency of ITI of 30% NaCl in 5 months old calves. In Experiment 1, control calves were only restrained and compared to calves submitted to castration through surgery (SC) and ITI with 20% NaCl (n = 9/group)...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28154019/mib1-index-stratified-assessment-of-dual-tracer-pet-ct-with-68ga-dotatate-and-18f-fdg-and-multimodality-anatomical-imaging-in-metastatic-net-of-unknown-primary-cup-net-scheduled-for-prrt
#8
Nikita Sampathirao, Sandip Basu
AIM: Comparative assessment of dual tracer PET/CT ((68)Ga-DOTATATE and (18)F-FDG) and multimodality anatomical imaging in studying CUP-NETs scheduled for PRRT for: (i) divergence of tracer uptake on dual tracer PET/CT, (ii) detection of primary and (iii) overall lesion detection vis-a-vis tumor proliferation index (Mib1/Ki-67). MATERIALS AND METHODS: Fifty-one patients of CUP-NETs (M:F=25:26, age:22-74 years), histopathologically proven and thoroughly investigated with conventional imaging modalities (USG, CT/ceCT, MRI and EUS, wherever applicable), were retrospective analyzed...
February 2, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28152401/123i-metaiodobenzylguanidine-myocardial-scintigraphy-with-early-images-alone-is-useful-for-the-differential-diagnosis-of-dementia-with-lewy-bodies
#9
Yuta Manabe, Yoshitaka Inui, Hiroshi Toyama, Kenji Kosaka
123I-metaiodobenzylguanidine cardiac scintigraphy (MIBG) is a useful imaging technique for the diagnosis of dementia with Lewy bodies (DLB). However, MIBG has a serious disadvantage in that it demands a long examination time. The objective of this study was to evaluate statistically the usefulness of the heart/mediastinum ratio (H/M) from the early phase of MIBG for the differential diagnosis of DLB. In total, 113 patients were examined, including 32 non-DLB (19 with Alzheimer's dementia) and 79 DLB patients...
January 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28150061/descending-necrotizing-mediastinitis-with-lemierre-s-syndrome
#10
Taisuke Kaiho, Takahiro Nakajima, Shuji Yonekura, Sawako Hamasaki, Takekazu Iwata, Ichiro Yoshino
Descending necrotizing mediastinitis is a severe infection of the mediastinum. Lemierre's syndrome manifests as thrombophlebitis in the cervical veins, which is caused by a neck infection. A 50-year-old woman had a fever with a 13-day history of neck pain. CT showed a deep neck abscess with vertebral vein thrombosis and mediastinal abscesses. Multiple small pulmonary nodules were found, suggesting septic pulmonary embolism. Emergency surgery for bilateral cervical and mediastinal drainage was performed, and antibiotics and anticoagulation agent was administered...
February 1, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28149747/an-unusual-thoracic-localizations-of-erdheim-chester-disease-a-case-report
#11
C Massaccesi, S Colella, F Fioretti, V D'Emilio, G Panella, G Primomo, F Barbisan, R Pela, V Poletti
Erdheim- Chester disease is a rare non- Langerhans cell histiocytosis that usually involves the bones, heart, central nervous system, retroperitoneum, eyes, kidneys, skin and adrenals. Lungs are affected in up to one-half cases; at CT scan various patterns are described: interstitial disease, consolidations, micronodules and microcysts, with or without pleural involvement. We presented a case of a 59 year-old man with unusual intrathoracic manifestation of Erdheim- Chester disease. Singularities of our report are the lonely thoracic involvement at the onset of the disease and a histiocytic lesion in the posterior mediastinum...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28149581/recent-advances-in-diagnostic-bronchoscopy
#12
REVIEW
Philip G Ong, Labib G Debiane, Roberto F Casal
The field of diagnostic bronchoscopy has been revolutionized in the last decade primarily with the advent of endobronchial ultrasound (EBUS) but also with the addition of multiple different techniques for "guided-bronchoscopy". These advances have had a substantial impact in the management of lung cancer with bronchoscopy now providing both diagnosis and mediastinal staging in a single procedure. EBUS has, in fact, become the first choice for staging of the mediastinum over cervical mediastinoscopy (CM). Although EBUS is now a well-established technique, there are continuous efforts from the scientific community to improve its diagnostic performance, and these will be reviewed in this manuscript...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28147469/thymoma-and-synchronous-primary-mediastinal-seminomas-with-florid-follicular-lymphoid-hyperplasia-in-the-anterior-mediastinum-a-case-report-and-review-of-the-literature
#13
Hyang-Im Lee, In-Seok Jang, Kyung Nyeo Jeon, Gyung Hyuck Ko, Jong Sil Lee, Dong Chul Kim, Dae Hyun Song, Jeong-Hee Lee
Thymoma is the most common neoplasm of the anterior mediastinum and has malignant potential. Germ cell tumors (GCTs) found in the anterior mediastinum are usually benign, and malignant GCTs, such as seminomas, are rare. Histologically, mediastinal seminoma is indistinguishable from testicular seminoma except for site-associated morphological features such as lymphoid follicular hyperplasia. Therefore, excluding metastasis is very important. Recently, we treated a young adult patient with multiple thymic masses that occurred simultaneously...
February 2, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28146439/air-in-all-the-wrong-places
#14
Benson S Hsu, Sarah A Jones-Sapienza
Extraluminal air can occur through a wide variety of mechanisms. Often, the free air resides in isolated regions including the thorax, the peritoneum, or the mediastinum. We present a pediatric case where there was extensive extraluminal air simultaneously within several regions, one of which has never been reported in the literature.
February 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28144908/the-association-between-liver-and-tumor-18-f-fdg-uptake-in-patients-with-diffuse-large-b-cell-lymphoma-during-chemotherapy
#15
Xingchen Wu, Abhisek Bhattarai, Pasi Korkola, Hannu Pertovaara, Hannu Eskola, Pirkko-Liisa Kellokumpu-Lehtinen
PURPOSE: The aim of this study was to explore the association between liver, mediastinum and tumor 2-deoxy-2-[(18)F]fluoro-D-glucose ([(18)F]FDG) uptake during chemotherapy in diffuse large B cell lymphoma (DLBCL). PROCEDURES: Nineteen patients with proven DLBCL underwent positron emission tomography (PET)/X-ray computed tomography scan at baseline, 1 week and 2 cycles after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) therapy, and again after chemotherapy completion...
January 31, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28142157/into-the-mediastinum-and-out-of-the-papilla-minimally-invasive-endoscopic-therapy-in-two-body-cavities-with-one-instrument
#16
Bernhard Magdeburg, Daniela B Husarik, Thomas Greuter
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28133561/thoracoscopic-surgery-for-glomus-tumor-an-uncommon-mediastinal-neoplasm-and-iatrogenic-tracheal-rupture
#17
Zhongjie Fang, Dehua Ma, Baofu Chen, Huarong Luo
Mediastinal glomus tumors are rarely recognized, and only seven cases have been reported in the literature. Here, we describe a rare mediastinal glomus tumor and review the characteristics of this rare clinical case. The patient was a 50-year-old female who presented with coughing for 3 months. Her chest computed tomography scan demonstrated a localized tumor in the posterior superior mediastinum. Intraoperatively, we found a longitudinal rupture of the membranous trachea above the carina. We completely resected the tumor and repaired the tracheal rupture under a thoracoscopy using a pedicled muscle flap...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28133334/-three-cases-of-gastric-cancer-with-rare-presentation-of-oncologic-emergency
#18
Yoshio Oka, Kaoru Okada, Yasuhiro Miyake, Shigeyuki Ueshima, Naozumi Higaki, Hirohito Hayashida, Riichiro Nezu
We report 3 cases of gastric cancer with rare presentations of oncologic emergency. Case 1 involved cardiac tamponade caused by mediastinitis-induced pericarditis. Metastatic lymph nodes became enlarged after total gastrectomy and invaded the esophagojejunal anastomotic region. Then, a fistula to the mediastinum occurred, resulting in mediastinitis. The drainage was efficacious, but the patient died of cancer 1 month after admission. Case 2 involved cardiac tamponade caused by invasion of metastatic peritoneal tumor into the pericardium...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133261/-pathological-complete-response-in-a-case-of-advanced-esophageal-cancer-with-widespread-lymph-node-metastases-treated-using-preoperative-chemotherapy-with-docetaxel-cisplatin-and-5-fu-dcf-therapy
#19
Hiroshi Noro, Takafumi Hirao, Shohei Takaichi, Chihyon Son, Kazuya Iwamoto, Emiko Kono, Keigo Yasumasa, Hitoshi Mizuno, Yoshikazu Morimoto, Nobutaka Hatanaka, Yoshio Yamasaki
The patient was a 66-year-old woman, who was diagnosed with cT3N3M0, cStage III esophageal cancer with widespread lymph node metastases in the mediastinum and abdomen. She was treated with 2 courses of chemotherapy with docetaxel/ cisplatin/5-FU(DCF therapy). CT and FDG PET-CT showed a significant reduction in both the primary tumor and the metastatic lymph nodes following treatment. We performed subtotal esophagectomy and gastric tube reconstruction with lymphadenectomy. The histopathological findings showed no residual viable tumor cells or foreign body-type giant cells with necrosis...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133253/-report-of-a-case-of-long-term-survival-with-mulitidisciplinary-therapy-for-a-patient-with-multiple-liver-metastases-from-rectal-cancer
#20
Yasuo Nagai, Masao Harano, Toshihiro Ogawa, Yasuhiro Komatsu, Naoki Mimura, Daisuke Satoh, Daisuke Sumitani, Yasuhiro Choda, Kanyu Nakano, Hiroyoshi Matsukawa, Yasutomo Ojima, Hitoshi Idani, Masazumi Okajima, Shigehiro Shiozaki, Tadashi Onoda
Multidisciplinary therapy is necessary to prevent recurrence of advanced rectal cancer and advanced cancer with metastases. Here we report a case of long-term survival of a patient with advanced rectal cancer with multiple liver metastases. An 80's woman had previously undergone both Hartmann's operation and a partial hepatectomy for advanced rectal cancer with multiple liver metastases. A year after chemotherapy, a CT scan revealed multiple liver metastases. Thus, we performed partial liver resection. After another round of chemotherapy, a CT scan revealed lung metastases and local recurrence of the rectal cancer; therefore, we performed partial lung resection and a Miles operation...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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