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https://www.readbyqxmd.com/read/28089791/supplement-ct-guided-microcoil-placement-for-localising-ggo-lesions-at-blind-areas-of-the-conventional-hook-wire-technique
#1
Tao Zuo, Shunbin Shi, Long Wang, Zhe Shi, Chenyang Dai, Chuanyi Li, Xiaogang Zhao, Zhengyi Ni, Ke Fei, Chang Chen
BACKGROUND: In the conventional hook-wire technique of pulmonary nodular localisations there are several "blind areas", including the mediastinum-vicinity region, interlobar fissure-neighbouring areas and scapulae-shadowed areas. The present study aims to summarise the experiences of CT-guided microcoil placement as an alternative method for localising pulmonary ground-glass opacity (GGO) lesions before thoracoscopic wedge resections. METHODS: Sixteen GGO lesions at "blind areas" in 16 patients were localised with platinum-fibered microcoils under CT assistance before undergoing video-assisted thoracoscopic surgical resections...
November 19, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28086809/primary-mediastinal-clear-cell-sarcoma-a-case-report-and-review-of-the-literature
#2
Long Jin, Yuxia Sui, Haili Zhu, Zhizhong Chen, Shuguang Liu
BACKGROUND: Clear cell sarcoma (CCS) is a rare malignant soft-tissue neoplasm that displays melanocytic markers and exhibits striking histopathological features. The tumour has a predilection for the lower extremities and rarely presents in the mediastinum. CASE PRESENTATION: We present a case of primary mediastinal CCS in a 57-year-old man. Computer tomography (CT) revealed a 12 × 12 × 7.5 cm mass in the anterior mediastinum. Microscopically, the tumour mainly consisted of epithelioid cells with oval vesicular nuclei and eosinophilic cytoplasm...
January 13, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28078796/hyperparathyroidism-caused-by-distant-pulmonary-lesions-and-parathyromatosis-after-ethanol-injection-parathyroidectomy-for-secondary-hyperparathyroidism
#3
Michio Nakamura, Kiho Tanaka, Takeshi Fujii
Secondary hyperparathyroidism (SHPT) treatment includes parathyroidectomy and percutaneous ethanol injection therapy (PEIT), which are invasive procedures. The condition in which benign hyperfunctioning parathyroid tissue is distributed throughout the neck and mediastinum is termed parathyromatosis. Here, we present the case of a 51-year-old woman who began hemodialysis in 1986 due to chronic kidney disease of unknown etiology and developed SHPT in 1999. She underwent 6 rounds of PEIT followed by total a parathyroidectomy with partial forearm autotransplantation...
January 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28070734/significant-correlation-between-renal-123-i-metaiodobenzylguanidine-scintigraphy-and-muscle-sympathetic-nerve-activity-in-patients-with-primary-hypertension
#4
Masayuki Takamura, Hisayoshi Murai, Yoshitaka Okabe, Yuji Okuyama, Takuto Hamaoka, Yusuke Mukai, Hideki Tokuhisa, Oto Inoue, Shin-Ichiro Takashima, Takeshi Kato, Shinro Matsuo, Soichiro Usui, Hiroshi Furusho, Shuichi Kaneko
BACKGROUND: Iodine-123 metaiodobenzylguanidine ((123)I-MIBG) scintigraphy is used as a noninvasive imaging method for assessing cardiac sympathetic nerve activity. We tested the hypothesis that renal (123)I-MIBG imaging is correlated with muscle sympathetic nerve activity (MSNA) in patients with primary hypertension. METHODS: Thirty-one consecutive patients with primary hypertension were included. Multiunit MSNA was recorded from the peroneal nerve to evaluate direct efferent sympathetic nerve activity...
January 9, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28062891/surgical-techniques-for-esophageal-replacement-in-children
#5
REVIEW
Shilpa Sharma, Devendra K Gupta
PURPOSE: Surgical techniques for esophageal replacement (ER) in children include colon interposition, gastric tube, gastric transposition, and jejunal interposition. This review evaluates the merits and demerits of each. METHOD: Surgical techniques, complications, and outcome of ER are reviewed over last seven decades. RESULTS: Colon interposition is the time-tested procedure with minimal and less serious complications. Long-term complications include reflux, halitosis, colonic segment dilatation, and anastomotic stricture, sometimes requiring surgical interventions especially for dilatation and reflux...
January 6, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28057967/massive-thymoma-of-the-mid-posterior-mediastinum-an-unprecedented-case-in-a-young-adult
#6
Karen Fernandes de Oliveira, Marcio Maciel Rodrigues, Gesner Pereira Lopes, Renan Sandoval de Almeida, Juliana Lopes Lusvarghi, João Paulo Vieira Dos Santos
We report an unprecedented case of ectopic thymoma in a young adult. A 33-year-old male presented with a 10-day history of non-productive cough and fever. Investigation revealed mediastinal widening without pulmonary involvement. Computed tomography showed a large mass-14.8 × 10.8 × 8.4 cm-in the mid-posterior mediastinum, and a biopsy obtained by video-assisted thoracoscopy indicated that the mass was a tumor. Immunohistochemistry showed combined thymoma type AB1. Because of the considerable proportions of the tumor and its close proximity to major structures, the patient was treated with chemotherapy...
November 2016: Radiologia Brasileira
https://www.readbyqxmd.com/read/28055250/assessment-of-chest-ct-at-ctdivol-less-than-1-mgy-with-iterative-reconstruction-techniques
#7
Atul Padole, Subba Digumarthy, Efren Flores, Rachna Madan, Shelly Mishra, Amita Sharma, Mannudeep K Kalra
OBJECTIVES: To assess the image quality of chest CT reconstructed with image-based (SafeCT), adaptive statistical (ASIR), and model based (MBIR) iterative reconstruction techniques (IRTs) at CTDIvol less than 1 mGy. METHODS: In an IRB approved study, 25 patients gave written informed consent for acquisition of three Reduced Dose (RD) (0.25, 0.4, 0.8 mGy) chest CT after standard of care CT (8 mGy) on a 64-channel multi-detector CT (MDCT) and reconstructed with SafeCT, ASIR, and MBIR...
January 5, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28048803/su-f-t-152-experimental-validation-and-calculation-benchmark-for-a-commercial-monte-carlo-pencil-beamscanning-proton-therapy-treatment-planning-system-in-heterogeneous-media
#8
L Lin, S Huang, M Kang, C Ainsley, C Simone, J McDonough, T Solberg
PURPOSE: Eclipse AcurosPT 13.7, the first commercial Monte Carlo pencil beam scanning (PBS) proton therapy treatment planning system (TPS), was experimentally validated for an IBA dedicated PBS nozzle in the CIRS 002LFC thoracic phantom. METHODS: A two-stage procedure involving the use of TOPAS 1.3 simulations was performed. First, Geant4-based TOPAS simulations in this phantom were experimentally validated for single and multi-spot profiles at several depths for 100, 115, 150, 180, 210 and 225 MeV proton beams, using the combination of a Lynx scintillation detector and a MatriXXPT ionization chamber array...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048675/tu-fg-209-07-medical-physics-1-0-versus-medical-physics-2-0-a-case-study
#9
D Carver, C Willis, P Stauduhar, T Nishino, J Wells, E Samei
PURPOSE: To illustrate how performance analytics can identify performance decrement in digital radiography systems. METHODS: Subsequent to a radiologist's image quality complaint, four different advanced methods contributed to root cause analysis. Our system was a GE Revolution XQi digital radiography unit. Initially, we reviewed weekly GE Quality Assurance Procedures (QAP) results in a database dating from 2001. Next, we evaluated objective image quality metrics of individual PA Chest radiographs acquired...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048524/su-f-t-356-dosimetriccomparison-of-vmat-vs-step-and-shoot-imrt-plans-for-stage-iii-lung-cancerpatients-with-mediastinal-involvement
#10
D Pearson, J Bogue
PURPOSE: For Stage III lung cancers that entail treatment of some or all of the mediastinum, anterior-posterior focused Step and Shoot IMRT (SS-IMRT) and VMAT plans have been clinically used to deliver the prescribed dose while working to minimize lung dose and avoid other critical structures. A comparison between the two planning methods was completed to see which treatment method is superior and minimizes dose to healthy lung tissue. METHODS: Ten patients who were recently treated with SS-IMRT or VMAT plans for Stage III lung cancer with mediastinal involvement were selected...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047745/su-f-t-416-dosimetric-comparison-of-coplanar-and-non-coplanar-imrt-plans-for-peripheral-lung-lesion
#11
J Kang, S Zhang, S Philbrook, S Paul, B Wang
PURPOSE: The purpose of this study was to compare dosimetric parameters of treatment plans between coplanar and non-coplanar techniques for treating peripheral lung lesions. METHODS: The planning CT scans of 6 patients in supine positions were used in this study. The size of the PTV ranges from 163 c.c. to 782 c.c.. The locations of PTV are mostly at the peripheral of Lung, some spreading to the mediastinum. For each patient, we generated two IMRT plans, one with and the other without non-coplanar beams...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047251/tu-h-campus-jep2-02-interobserver-variability-of-ct-pet-ct-and-mri-based-primary-tumor-delineation-for-lung-cancer
#12
K Karki, G Hugo, S Saraiya, N Jan, J Schuster, M Schutzer, L Fahrner, R Groves, J Ford, E Weiss
PURPOSE: Target delineation in lung cancer radiotherapy has, in general, large variability. MRI has so far not been investigated in detail for lung cancer delineation variability. The purpose of this study is to investigate delineation variability for lung tumors using MRI and compare it to CT alone and PET-CT based delineations. METHODS: Seven physicians delineated the primary tumor volumes of nine patients for the following scenarios: (1) CT only; (2) post-contrast T1-weighted MRI registered with diffusion-weighted MRI; and (3) PET-CT fusion images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047210/th-ab-bra-07-penelope-based-gpu-accelerated-dose-calculation-system-applied-to-mri-guided-radiation-therapy
#13
Y Wang, T Mazur, O Green, Y Hu, H Li, V Rodriguez, H Wooten, D Yang, T Zhao, S Mutic, H Li
PURPOSE: The clinical commissioning of IMRT subject to a magnetic field is challenging. The purpose of this work is to develop a GPU-accelerated Monte Carlo dose calculation platform based on PENELOPE and then use the platform to validate a vendor-provided MRIdian head model toward quality assurance of clinical IMRT treatment plans subject to a 0.35 T magnetic field. METHODS: We first translated PENELOPE from FORTRAN to C++ and validated that the translation produced equivalent results...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047061/su-f-r-07-radiomics-of-ct-features-and-associations-and-correlation-with-outcomes-following-lung-sbrt
#14
E Schreibmann, A Iwinski Sutter, D Whitaker, J Switchenko, E Elder, K Higgins, P Patel
OBJECTIVE: To investigate the prognostic significance of image gradients and in predicting clinical outcomes in a patients with non-small cell lung cancer treated with stereotactic body radiotherapy (SBRT) on 71 patients with 83 treated lesions. METHODS: The records of patients treated with lung SBRT were retrospectively reviewed. When applicable, SBRT target volumes were modified to exclude any overlap with pleura, chestwall, or mediastinum. The ITK software package was utilized to generate quantitative measures of image intensity, inhomogeneity, shape morphology and first and second-order CT textures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046973/su-f-r-14-pet-based-radiomics-to-predict-outcomes-in-patients-with-hodgkin-lymphoma
#15
J Lee, M Aristophanous, M Akhtari, S Milgrom, D Bouthaina, C Pinnix, S Narang, A Rao, L Court, G Smith
PURPOSE: To identify PET-based radiomics features associated with high refractory/relapsed disease risk for Hodgkin lymphoma patients. METHODS: A total of 251 Hodgkin lymphoma patients including 19 primary refractory and 9 relapsed patients were investigated. All patients underwent an initial pre-treatment diagnostic FDG PET/CT scan. All cancerous lymph node regions (ROIs) were delineated by an experienced physician based on thresholding each volume of disease in the anatomical regions to SUV>2...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044305/clinicopathological-analysis-of-mediastinal-masses-a-mixed-bag-of-non-neoplastic-and-neoplastic-etiologies
#16
Preeti Sharma, Vidya Jha, Naveen Kumar, Rohit Kumar, Ashish Mandal
OBJECTIVE: The mediastinum is the central portion of the thoracic cavity, housing numerous organs and harbouring a mixed bag of non-neoplastic and neoplastic lesions. Accurate diagnosis is essential owing to the widely variable therapeutic and prognostic implications. MATERIAL AND METHOD: Cases of mediastinal masses were retrospectively reviewed from January 2011 till January 2016. Clinico-radiological records of these cases were retrieved. Fine needle aspiration cytology (FNAC) was performed wherever feasible...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28044001/resection-of-giant-mediastinal-liposarcoma-via-%C3%A2-shape-incision
#17
Wei Huang, Ge Ning Jiang
Primary mediastinal liposarcomas are extremely rare conditions often resected through standard median sternotomy or lateral thoracotomy. However, the management of a very huge mediastinal tumor involving hemithorax through these two common surgical approaches is always challenging. Herein, we report a case of applying median sternotomy with a sternum transection plus a right fourth intercostal thoracotomy ('⊣ shape' incision) to resect a giant primary anterior mediastinal liposarcoma extending into the whole right thorax...
January 2, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28040761/penetration-of-bronchial-wall-by-knot-of-absorbable-monofilament-suture
#18
Tomoyuki Nakano, Shunsuke Endo, Hideki Negishi, Shinichi Yamamoto
A 75-year-old man underwent thoracoscopic left upper lobectomy for primary lung cancer. Additional ligature plication to the left superior pulmonary vein with absorbable monofilament suture was performed after stapling with an endostapler. Postoperative bronchoscopy revealed penetration of the monofilament thread edge eviscerating across the wall of the left main bronchus. The edge was spontaneously absorbed with no adverse events. Penetration of a thick monofilament thread edge into mediastinal organs should be considered when the thread is located in the mediastinum...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28034523/prognostic-significance-of-epstein-barr-virus-ebv-infection-in%C3%A2-hodgkin-lymphoma-patients
#19
Ben Dhiab Myriam, Ziadi Sonia, Saad Hanene, Louhichi Teheni, Trimeche Mounir
INTRODUCTION: The prognostic significance of Epstein-Barr virus (EBV) infection in Hodgkin lymphoma (HL) is still controversial. In this work we sought to examine the prognostic differences between EBV-positive and -negative HL through a series of 131 cases from Tunisia. METHODS: The status of EBV was assessed by EBV-encoded RNA (EBER) in situ hybridization. Results were correlated to patients' characteristics and outcome. RESULTS: EBV was detected in the malignant cells in 62 of 131 HL cases (47...
December 26, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28031857/giant-mature-teratoma-in-the-mediastinum-presenting-with-rapid-growth
#20
Kohei Fujita, Kazuki Hayashi, Makoto Motoishi, Satoru Sawai, Tsuyoshi Terashima, Tadashi Mio
Teratomas are primary germ-cell tumours in the mediastinum. Although they are generally slow-growing and asymptomatic, rapid growth causing life-threatening complications can occur. Sebaceous secretion, insulin production, chorionic gonadotropin secretion and pancreatic enzyme secretion are the presumptive causes of tumour progression. Only few cases of rapidly growing teratomas have been reported previously. Here, we present a case of a giant mature teratoma in the mediastinum that presented with rapid growth and compare the characteristics of this case with those of previous cases...
December 2016: Oxford Medical Case Reports
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