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https://www.readbyqxmd.com/read/28944981/a-qualitative-study-on-the-attributes-of-nurses-workplace-social-capital-in-japan
#1
Kensuke Norikoshi, Toshio Kobayashi, Keiji Tabuchi
AIM: To identify attributes of nurses' workplace social capital in Japan. BACKGROUND: Much attention has been paid to nurses' workplace social capital to improve the quality of the work environment; however, few studies are available on the attributes of nurses' workplace social capital. METHODS: Semi-structured interviews were conducted with 32 nurses at seven hospitals. Nurses reported on the attributes of workplace social capital, such as characteristics facilitating individual positive action in an organisation, which were qualitatively analysed using the Kawakita Jiro method...
September 25, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28944483/morbidity-and-mortality-associated-with-preclinical-tracheostomy-models
#2
Gregory R Dion, Peter A Benedict, Milan R Amin, Ryan C Branski
OBJECTIVES/HYPOTHESIS: A secure airway is critical to study obstructive disorders of the larynx and trachea in preclinical models. Tracheostomy has been described in rabbits, swine, canines, and other mammals using tracheostomy tubes or permanent stomas. No studies specifically evaluated morbidity and mortality associated with these models, and existing studies using tracheostomy make little mention of tracheostomy-related complications. We assessed the management, complications, and mortality associated with tracheostomy in a rabbit model that has recently gained significant attention...
September 25, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28943807/the-maternal-non-responsiveness-questionnaire-initial-factor-structure-and-validation
#3
Esther Leerkes, Jin Qu
The purpose of this paper was to examine the reliability, stability, and convergent and predictive validity of the newly developed Maternal Responsiveness Questionnaire (MRQ). Participants were 224 first-time mothers. Mothers completed the MRQ when their infants were 6 and 14 months old. Convergent validity was examined in relation to mother-reported personality, depressive symptoms, and emotion socialization practices and observed maternal sensitivity. Predictive validity was examined in relation to mother-reported child behavior problems and social competence, infant attachment security assessed via the Strange Situation, and observed child dysregulation...
May 2017: Infant and Child Development
https://www.readbyqxmd.com/read/28943064/endostapler-versus-hem-o-lok-clip-to-secure-the-appendiceal-stump-and-mesoappendix-during-laparoscopic-appendectomy
#4
Mohammed H Al-Temimi, Mendy A Berglin, Edwin G Kim, Deron J Tessier, Samir D Johna
BACKGROUND: Our study evaluates the safety and cost of using the Hem-O-Lok (HOL) clip in laparoscopic appendectomy (LA). METHOD: We prospectively compared 30-day postoperative outcomes and cost between HOL clip and endoscopic stapler (ES) in LA at a single institution. RESULTS: HOL clip was used in 45 out of 92 LA. Perforated appendicitis (29.8% vs. 11.1%, P = 0.027) and postoperative complications were more common in the ES group (19.2% vs...
September 18, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28942967/de-novo-mutations-in-ppp3ca-cause-severe-neurodevelopmental-disease-with-seizures
#5
Candace T Myers, Nicholas Stong, Emily I Mountier, Katherine L Helbig, Saskia Freytag, Joseph E Sullivan, Bruria Ben Zeev, Andreea Nissenkorn, Michal Tzadok, Gali Heimer, Deepali N Shinde, Arezoo Rezazadeh, Brigid M Regan, Karen L Oliver, Michelle E Ernst, Natalie C Lippa, Maureen S Mulhern, Zhong Ren, Annapurna Poduri, Danielle M Andrade, Lynne M Bird, Melanie Bahlo, Samuel F Berkovic, Daniel H Lowenstein, Ingrid E Scheffer, Lynette G Sadleir, David B Goldstein, Heather C Mefford, Erin L Heinzen
Exome sequencing has readily enabled the discovery of the genetic mutations responsible for a wide range of diseases. This success has been particularly remarkable in the severe epilepsies and other neurodevelopmental diseases for which rare, often de novo, mutations play a significant role in disease risk. Despite significant progress, the high genetic heterogeneity of these disorders often requires large sample sizes to identify a critical mass of individuals with disease-causing mutations in a single gene...
September 15, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28942019/failure-patterns-in-standalone-anterior-cervical-discectomy-and-fusion-implants
#6
Fernando Alonso, Tarush Rustagi, Cameron Schmidt, Daniel C Norvell, R Shane Tubbs, Rod J Oskouian, Jens R Chapman, Christian Fisahn
INTRODUCTION: Anterior cervical discectomy and fusion is commonly performed using an allograft or autograft implant and anterior screw-supported plate. There has been an increase in the use of standalone cage devices due to ease of use and studies suggesting a lower rate of acute post-operative dysphagia. We review our experience with standalone cage devices and identify risk factors, patterns of failure, and revision surgery approaches. MATERIALS AND METHODS: We performed a retrospective case-series of patients treated at a single tertiary care institution between March 2014 and March 2015...
September 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28941794/evading-plant-defence-infestation-of-poisonous-milkweed-fruits-asclepiadaceae-by-the-fruit-fly-dacus-siliqualactis-diptera-tephritidae
#7
Michael Schneider, Cora Wunder, Esther Reuss, Stefan W Toennes, Dietrich Mebs
To cope with toxic metabolites plants use for defence, herbivorous insects employ various adaptive strategies. For oviposition, the fruit fly Dacus siliqualactis (Tephritidae) uses milkweed plants of the genus Gomphocarpus (Asclepiadaceae) by circumventing the plant's physical (gluey latex) and chemical (toxic cadenolides) defence. With its long, telescope-like ovipositor, the fly penetrates the exo- and endocarp of the fruit and places the eggs on the unripe seeds located in the centre of the fruit. Whereas most plant parts contain high concentrations of cardenolides such as gomphoside, calotropin/calacatin and gomphogenin, only the seeds exhibit low cardenolide levels...
September 20, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28941524/juvenile-macular-degenerations
#8
Pablo Altschwager, Lucia Ambrosio, Emily A Swanson, Anne Moskowitz, Anne B Fulton
In this article, we review the following 3 common juvenile macular degenerations: Stargardt disease, X-linked retinoschisis, and Best vitelliform macular dystrophy. These are inherited disorders that typically present during childhood, when vision is still developing. They are sufficiently common that they should be included in the differential diagnosis of visual loss in pediatric patients. Diagnosis is secured by a combination of clinical findings, optical coherence tomography imaging, and genetic testing...
May 2017: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/28941346/-progress-in-improving-photosynthetic-efficiency-by-synthetic-biology
#9
Lixin Zhang, Congming Lu, Lianwei Peng, Weimin Ma, Wanqiang Qian
The contradiction between the increasing population and the decrease of tillable land areas is becoming more and more serious in our country. Food security is an important guarantee for sustainable development of our national economy. Photosynthesis is the basis for crop yield. Improving crop photosynthetic efficiency is one of the important approaches to increase crop yield. In this review, we summarized the recent advances in engineering photosynthetic performance by synthetic biology from three key aspects including absorption, transduction and conversion of light energy, light utilization efficiency and carbon assimilation...
March 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28940495/understanding-the-potential-for-patient-engagement-in-electronic-consultation-and-referral-systems-lessons-from-one-safety-net-system
#10
Jacqueline Nwando Olayiwola, Margae Knox, Kate Dubé, Emily Chen-Yuan Lu, Tem Woldeyesus, Iguehi E James, Rachel Willard-Grace, Delphine Tuot
OBJECTIVE: To understand patient, primary care clinician (PCC), and subspecialist perspectives on potential, unexplored roles for patients in electronic consultation and referral (eCR) systems. DATA SOURCES: Primary focus group and survey data collected April-November 2015. Zuckerberg San Francisco General Hospital (ZSFG) is part of an integrated public health delivery system. Its mature eCR system was first implemented in 2005. STUDY DESIGN: This mixed-methods study synthesizes patient, subspecialist, and PCC perspectives through two patient focus groups in English, Spanish, and Cantonese (n = 6); subspecialist focus groups (n = 2); and an electronic survey of all PCCs (n = 222/634, 35 percent response)...
September 20, 2017: Health Services Research
https://www.readbyqxmd.com/read/28940462/social-security-disability-insurance-enrollment-and-health-care-employment
#11
Lawrence C Pellegrini, Kimberley H Geissler
OBJECTIVE: To examine the relationship between Social Security Disability Insurance (SSDI) enrollment and health care employment. DATA SOURCES: State-year level data from government and other publicly available sources for all states (2000-2014). STUDY DESIGN: Population-weighted linear regression analyses model associations between each health care employment measure and each SSDI enrollment measure (i.e., SSDI overall, physical, or mental health enrollment rates), controlling for factors associated with health care employment, state fixed effects, and secular time trends...
September 21, 2017: Health Services Research
https://www.readbyqxmd.com/read/28940212/no-induced-mutagenesis-in-human-lymphoblast-cell-line-and-bacterial-systems-upon-their-prolonged-sub-culturing-in-irradiated-food-blended-media
#12
Sudhanshu Saxena, Sanjeev Kumar, Jyoti Tripathi, Satyendra Gautam
BACKGROUND: Confound apprehension towards safety of irradiated food has remained a major cause behind tardy acceptance of this technology though it has immense socio-economic potential. Generation of in depth scientific evidences will help to refute these apprehensions. With this prospective, present study was undertaken where safety of various irradiated (Dmin up to 25 kGy) foods was evaluated through long term exposure studies in models including human lymphoblast TK6 cell line (100 generations) and Escherichia coli MG1655 cells (exclusive subcuturing in irradiated food medium for 3000 generations)...
September 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28940136/residents-perceive-limited-education-on-family-planning-and-contraception-for-patients-with-severe-and-persistent-mental-illness
#13
Matthew Macaluso, Rosey Zackula, Christina Bowman, Christina Bourne, Donna Sweet
OBJECTIVE: The primary goal of this study was to assess perceived adequacy of training by residents from multiple specialties on contraceptive prescribing and family planning for patients with severe and persistent mental illness (SPMI). Secondary goals included the following: (1) explore resident knowledge, attitudes, and behavior towards patients with SPMI and (2) identify barriers to meeting the reproductive health needs of patients with SPMI. METHODS: The target population was 44,237 residents from four medical specialties...
September 22, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28940009/print-to-detect-a-rapid-and-ultrasensitive-phage-based-dipstick-assay-for-foodborne-pathogens
#14
Hany Anany, Lubov Brovko, Noha K El Dougdoug, Jennifer Sohar, Heather Fenn, Nada Alasiri, Tarik Jabrane, Patrice Mangin, M Monsur Ali, Balamurali Kannan, Carlos D M Filipe, Mansel W Griffiths
Foodborne pathogens are a burden to the economy and a constant threat to public health. The ability to rapidly detect the presence of foodborne pathogens is a vital component of any strategy towards establishing a safe and secure food supply chain. Bacteriophages (phages) are viruses capable of infecting and replicating within bacteria in a strain-specific manner. The ubiquitous and selective nature of phages makes them ideal for the detection and biocontrol of bacteria. Therefore, the objective of this research was to develop and test a phage-based paper dipstick biosensor for the detection of various foodborne pathogens in food matrices...
September 22, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28939989/the-cotesia-sesamiae-story-insight-into-host-range-evolution-in-a-hymenoptera-parasitoid-and-implication-for-its-use-in-biological-control-programs
#15
REVIEW
L Kaiser, S Dupas, A Branca, E A Herniou, C W Clarke, C Capdevielle Dulac, J Obonyo, R Benoist, J Gauthier, P A Calatayud, J F Silvain, B P Le Ru
This review covers nearly 20 years of studies on the ecology, physiology and genetics of the Hymenoptera Cotesia sesamiae, an African parasitoid of Lepidoptera that reduces populations of common maize borers in East and South Africa. The first part of the review presents studies based on sampling of C. sesamiae from maize crops in Kenya. From this agrosystem including one host plant and three main host borer species, studies revealed two genetically differentiated populations of C. sesamiae species adapted to their local host community, and showed that their differentiation involved the joint evolution of virulence genes and sensory mechanisms of host acceptance, reinforced by reproductive incompatibility due to Wolbachia infection status and natural inbreeding...
September 22, 2017: Genetica
https://www.readbyqxmd.com/read/28939761/rapid-secure-drug-testing-using-fingerprint-development-and-paper-spray-mass-sspectrometry
#16
Catia Costa, Roger Webb, Vladimir Palitsin, Mahado Ismail, Marcel de Puit, Samuel Atkinson, Melanie J Bailey
BACKGROUND: Paper spray mass spectrometry(6) is a technique that has recently emerged and has shown excellent analytical sensitivity to a number of drugs in blood. As an alternative to blood, fingerprints have been shown to provide a noninvasive and traceable sampling matrix. Our goal was to validate the use of fingerprint samples to detect cocaine use. METHODS: Samples were collected on triangular pieces (168 mm(2)) of washed Whatman Grade I chromatography paper...
September 22, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28939172/pearl-millet-genome-lessons-from-a-tough-crop
#17
Marilyne Debieu, Ghislain Kanfany, Laurent Laplaze
Pearl millet is an important cereal for food security in the arid regions of Africa and India. The recently published genome of this tough cereal crop has shed new light on its history and adaptation to dry, hot climates and paves the way for much-needed genomic-based breeding efforts.
September 19, 2017: Trends in Plant Science
https://www.readbyqxmd.com/read/28939079/transoral-bisected-resection-for-t1-2-oral-tongue-squamous-cell-carcinoma-to-secure-adequate-deep-margin
#18
Nayeon Choi, Jae-Keun Cho, Eun Kyu Lee, Sung Jun Won, Bo Young Kim, Chung-Hwan Baek
BACKGROUND: To investigate the clinical usefulness of transoral bisected resection (TBR) asa new method to secure adequate deep resection margin in T1-2 oral tongue squamous cell carcinomas (SCC). METHODS: Among 75 patients with cT1-2N0 oral tongue SCCs, 45 (60%) received transoral en-bloc resection (TER) while 30 (40%) received patients underwent TBR. Primary tumor resection was performed with 1.5-cm surgical resection margin for both groups. Mucosal and deep resection margins, adjuvant treatments including re-resection of the tongue and cheomoradiotherapy, local and regional recurrence free survival, and overall survival were compared between the two groups...
October 2017: Oral Oncology
https://www.readbyqxmd.com/read/28939010/-evaluation-of-the-prescription-of-proton-pump-inhibitors-in-persons-aged-75years-and-older-in-a-geriatric-acute-care-unit
#19
Mélanie Dipanda, Laureline Pioro, Maxime Buttard, Philippe d'Athis, Sanaa Asgassou, Sophie Putot, Martha Deïdda, Caroline Laborde, Alain Putot, Patrick Manckoundia
INTRODUCTION AND OBJECTIVES: Proton pump inhibitors (PPI) are widely prescribed in France and could be responsible for adverse drug reactions especially in elderly persons (EP). In order to reduce the misuse of PPI and the excess cost to the Social Security Agency, the French health authorities (Haute Autorité de santé [HAS]) have published strict guidelines for their prescription. We conducted a study in EP to determine the proportion of PPI prescriptions outside HAS guidelines. METHOD: This was a prospective, single-centre observational study in persons aged≥75 years admitted to a geriatric acute-care unit over a period of 6months...
July 29, 2017: Thérapie
https://www.readbyqxmd.com/read/28938910/creating-a-data-resource-what-will-it-take-to-build-a-medical-information-commons
#20
Patricia A Deverka, Mary A Majumder, Angela G Villanueva, Margaret Anderson, Annette C Bakker, Jessica Bardill, Eric Boerwinkle, Tania Bubela, Barbara J Evans, Nanibaa' A Garrison, Richard A Gibbs, Robert Gentleman, David Glazer, Melissa M Goldstein, Hank Greely, Crane Harris, Bartha M Knoppers, Barbara A Koenig, Isaac S Kohane, Salvatore La Rosa, John Mattison, Christopher J O'Donnell, Arti K Rai, Heidi L Rehm, Laura L Rodriguez, Robert Shelton, Tania Simoncelli, Sharon F Terry, Michael S Watson, John Wilbanks, Robert Cook-Deegan, Amy L McGuire
National and international public-private partnerships, consortia, and government initiatives are underway to collect and share genomic, personal, and healthcare data on a massive scale. Ideally, these efforts will contribute to the creation of a medical information commons (MIC), a comprehensive data resource that is widely available for both research and clinical uses. Stakeholder participation is essential in clarifying goals, deepening understanding of areas of complexity, and addressing long-standing policy concerns such as privacy and security and data ownership...
September 22, 2017: Genome Medicine
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