F Bayraktar, L Kebapcilar, M A Kocdor, S L Asa, S Yesil, S Canda, T Demir, A Saklamaz, M Seçil, B Akinci, S Yener, A Comlekci
Ectopic production of corticotropin-releasing hormone (CRH) by a pheochromocytoma is an infrequent cause of Cushing's syndrome. We report the case of a 43-year-old man with Cushing's syndrome due to a CRH-producing adrenal pheochromocytoma. The patient had clinical and biochemical evidence of hypercortisolism in conjunction with high ACTH levels and non-suppressible serum cortisol levels on low-dose and high-dose dexamethasone suppression testing. In addition to these clinical features of one month's duration, the patient developed symptoms of pheochromocytoma including headache, hypertension that was resistant to conventional therapy and excessive sweating...
September 2006: Experimental and Clinical Endocrinology & Diabetes