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https://www.readbyqxmd.com/read/23624119/repeated-administration-of-ac-5216-a-ligand-for-the-18-kda-translocator-protein-improves-behavioral-deficits-in-a-mouse-model-of-post-traumatic-stress-disorder
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Zhi-Kun Qiu, Li-Ming Zhang, Nan Zhao, Hong-Xia Chen, You-Zhi Zhang, Yan-Qin Liu, Tian-Yue Mi, Wen-Wen Zhou, Yang Li, Ri-Fang Yang, Jiang-Ping Xu, Yun-Feng Li
Post-traumatic stress disorder (PTSD) is a severely disabling anxiety disorder that may occur following exposure to a serious traumatic event. It is a psychiatric condition that can afflict anyone who has experienced a life-threatening or violent event. Previous studies have shown that changes in 18 kDa translocator protein (TSPO) expression (or function), a promising target for treating neurological disorders without benzodiazepine-like side effects, may correlate with PTSD. However, few studies have investigated the anti-PTSD effects of TSPO ligands...
August 1, 2013: Progress in Neuro-psychopharmacology & Biological Psychiatry
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