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One Health Initiative

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https://www.readbyqxmd.com/read/28938788/cd4-t-cells-dominate-the-leukocyte-infiltration-response-initiated-by-intra-dermal-injection-of-phytohemagglutinin-into-growing-feathers-in-chickens
#1
K S Sullivan, G F Erf
Phytohemagglutinin (PHA) is commonly used to evaluate cell-mediated immunocompetence. In chickens, PHA is typically injected intra-dermally (i.d.) into the skin (e.g., wing web, wattle, or footpad), and the tissue swelling response is monitored, whereby the extent of tissue swelling positively relates to the individual's cell-mediated immune system capabilities. Although i.d. injected PHA was shown to stimulate mononuclear cell and basophil infiltration to the site of injection, reports on temporal, qualitative, and quantitative aspects of the local cutaneous PHA response are limited...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28938738/resolution-of-infertility-and-number-of-children-1386-couples-followed-for-a-median-of-13-years
#2
A A Righarts, A Gray, N P Dickson, L Parkin, W R Gillett
STUDY QUESTION: How common were children among infertile couples? SUMMARY ANSWER: A total of 61.7% of infertile couples presenting for care subsequently had live born children 13.1 years after first being clinically assessed, with a mean of 1.7 children among those who had at least one. WHAT IS KNOWN ALREADY: While the prognoses for infertile couples undertaking specific treatments have been well described, less is known about those not undergoing these treatments or the total number of children...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28936948/control-of-clostridium-difficile-infection-by-defined-microbial-communities
#3
James Collins, Jennifer M Auchtung
Each year in the United States, billions of dollars are spent combating almost half a million Clostridium difficile infections (CDIs) and trying to reduce the ∼29,000 patient deaths in which C. difficile has an attributed role. In Europe, disease prevalence varies by country and level of surveillance, though yearly costs are estimated at €3 billion. One factor contributing to the significant health care burden of C. difficile is the relatively high frequency of recurrent CDIs. Recurrent CDI, i.e., a second episode of symptomatic CDI occurring within 8 weeks of successful initial CDI treatment, occurs in ∼25% of patients, with 35 to 65% of these patients experiencing multiple episodes of recurrent disease...
September 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28936808/impact-of-tocilizumab-monotherapy-on-clinical-and-patient-reported-quality-of-life-outcomes-in-patients-with-rheumatoid-arthritis
#4
Leslie R Harrold, Ani John, George W Reed, Tmirah Haselkorn, Chitra Karki, YouFu Li, Jennie Best, Steve Zlotnick, Joel M Kremer, Jeffrey D Greenberg
INTRODUCTION: Tocilizumab (TCZ) monotherapy has been proven as an effective treatment for rheumatoid arthritis (RA) in clinical trials. However, there are limited data available regarding the effectiveness of TCZ monotherapy in real-world clinical settings in the United States. The objective of this study was to evaluate the impact of TCZ monotherapy on disease activity and patient-reported outcomes (PROs) in a US-based observational cohort of patients with RA seen in routine clinical practice...
September 21, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28936229/determinants-of-infant-and-young-child-feeding-practices-by-mothers-in-two-rural-districts-of-sindh-pakistan-a-cross-sectional-survey
#5
Gul Nawaz Khan, Shabina Ariff, Ubaidullah Khan, Atif Habib, Muhammad Umer, Zamir Suhag, Imtiaz Hussain, Zaid Bhatti, Asmat Ullah, Ali Turab, Ali Ahmad Khan, Alba Cecilia Garzon, Mohammad Imran Khan, Sajid Soofi
BACKGROUND: Infant and young child feeding (IYCF) practices during the first two years of life are important for the growth and development of a child. The aim of this study was to assess IYCF practices and its associated factors in two rural districts of Pakistan. METHODS: A cross-sectional study was conducted in two rural districts of Sindh province, Pakistan as part of a stunting prevention project between May and August 2014. A standard questionnaire on IYCF practices recommended by World Health Organization was used to collect information from 2013 mothers who had a child aged between 0 and 23 months...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/28934786/long-term-cost-utility-of-spinal-cord-stimulation-in-patients-with-failed-back-surgery-syndrome
#6
S Harrison Farber, Jing L Han, Aladine A Elsamadicy, Qasim Hussaini, Siyun Yang, Promila Pagadala, Beth Parente, Jichun Xie, Shivanand P Lad
BACKGROUND: Failed back surgery syndrome (FBSS) is a cause of significant morbidity for up to 40% of patients following spine surgery, and is estimated to cost almost $20 billion. Treatment options for these patients currently include conventional medical management (CMM), repeat operation, or spinal cord stimulation (SCS). Much of the published data regarding cost effectiveness of SCS comprise smaller scale randomized controlled trials (RCTs) rather than large databases capturing practices throughout the US...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934773/leptospirosis-in-three-workers-on-a-dairy-farm-with-unvaccinated-cattle
#7
Jackie Benschop, Julie Collins-Emerson, Allie Maskill, Patrick O'Connor, Margaret Tunbridge, Yuni Yupiana, Jenny Weston
AIM: We report a one-health investigation of three cases of leptospirosis on a dairy farm with unvaccinated cattle in New Zealand. The cases are discussed in the context of diagnostics, risk factors, persistence of symptoms and outbreak mitigation measures. METHOD: Clinical and laboratory records from the human cases were reviewed and serological and molecular investigations were conducted into the Leptospira status of cattle and pigs on the farm. RESULTS: Cases presented early in their illness and all three were confirmed within seven days of onset of symptoms by urine PCR and within 18 days by convalescent MAT (two Hardjo-bovis, one Pomona)...
September 22, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28933709/evidence-for-misspecification-of-a-nationally-used-quality-measure-for-substance-use-treatment
#8
Soeren Mattke, Zachary Predmore, Elizabeth Sloss, Asa Wilks, Katherine E Watkins
OBJECTIVES: The National Committee for Quality Assurance's (NCQA) measure "Initiation and Engagement of Alcohol and Other Drug Dependence Treatment" captures the proportion of substance use patients with (1) treatment initiation within 14 days and (2) treatment engagement within 30 days thereafter. The definition of treatment considers only counseling but not medication-assisted treatment (MAT), although MAT is supported by current guidelines. Our research question is whether this omission results in meaningful measurement error...
September 4, 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28932268/therapeutic-drug-monitoring-of-ct-p13-a-comparison-of-four-different-immunoassays
#9
Joana Afonso, Helena Tavares de Sousa, Isadora Rosa, João Carvalho, Cláudia Camila Dias, Fernando Magro
BACKGROUND: The commercialization of CT-P13, an infliximab (IFX) biosimilar, has the potential to decrease health-related costs and enhance access to biological therapies. This study aimed to address the accuracy and inter-assay agreement of the CT-P13 quantification using four different assays initially developed to assess IFX. METHODS: The four different methods, one in-house method and three commercially available kits, were used to quantify exogenously-spiked samples and the sera from 185 inflammatory bowel disease (IBD) patients on CT-P13 therapy...
September 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28932255/determinants-of-breastfeeding-initiation-among-mothers-in-sydney-australia-findings-from-a-birth-cohort-study
#10
Amit Arora, Narendar Manohar, Andrew Hayen, Sameer Bhole, John Eastwood, Steven Levy, Jane Anne Scott
BACKGROUND: Breastfeeding has short-term and long-term benefits for both the infant and the mother. The objective of this study was to identify the incidence of breastfeeding initiation among women in South Western Sydney, and the factors associated with the initiation of breastfeeding. METHODS: Child and Family Health Nurses recruited mother-infant dyads (n = 1035) to the Healthy Smiles Healthy Kids birth study in South Western Sydney, an ethnically and socio-economically diverse area, at the first post-natal home visit...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/28931894/factors-generating-glucose-degradation-products-in-sterile-glucose-solutions-for-infusion-statistical-relevance-determination-of-their-impacts
#11
J Haybrard, N Simon, C Danel, C Pinçon, C Barthélémy, F J Tessier, B Décaudin, E Boulanger, P Odou
Sterilising glucose solutions by heat promotes the generation of a large number of glucose degradation products (GDPs). It has been shown that high levels of GDPs may result in Advanced Glycation End products that have an impact on cellular homeostasis and health in general. If data is available for peritoneal dialysis solutions, little has been published for glucose infusion fluids. It is essential to identify the parameters causing the formation of GDPs and so limit the risk of exposing patients to them. After quantifying both 5-hydroxymethyl-2-furfural, considered as an important indicator of degradation, and 2-furaldehyde, an ultimate GDP of one degradation pathway, in marketed solutions, the aim of this work is to build a model integrating all the parameters involved in the formation rates of these two GDPs: supplier, glucose amount, container material, oxygen permeability coefficient and time-lapse since manufacture...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931088/an-integrated-nutrition-and-health-program-package-on-iycn-improves-breastfeeding-but-not-complementary-feeding-and-nutritional-status-in-rural-northern-india-a-quasi-experimental-randomized-longitudinal-study
#12
Veena Singh, Saifuddin Ahmed, Michele L Dreyfuss, Usha Kiran, Deepika N Chaudhery, Vinod K Srivastava, Ramesh C Ahuja, Abdullah H Baqui, Gary L Darmstadt, Mathuram Santosham, Keith P West
BACKGROUND: Undernutrition below two years of age remains a major public health problem in India. We conducted an evaluation of an integrated nutrition and health program that aimed to improve nutritional status of young children by improving breast and complementary feeding practices over that offered by the Government of India's standard nutrition and health care program. METHODS: In Uttar Pradesh state, through multi-stage cluster random sampling, 81 villages in an intervention district and 84 villages in a comparison district were selected...
2017: PloS One
https://www.readbyqxmd.com/read/28930701/leukocyte-telomere-length-t-cell-composition-and-dna-methylation-age
#13
Brian H Chen, Cara L Carty, Masayuki Kimura, Jeremy D Kark, Wei Chen, Shengxu Li, Tao Zhang, Charles Kooperberg, Daniel Levy, Themistocles Assimes, Devin Absher, Steve Horvath, Alexander P Reiner, Abraham Aviv
Both leukocyte telomere length (LTL) and DNA methylation age are strongly associated with chronological age. One measure of DNA methylation age─ the extrinsic epigenetic age acceleration (EEAA)─ is highly predictive of all-cause mortality. We examined the relation between LTL and EEAA. LTL was measured by Southern blots and leukocyte DNA methylation was determined using Illumina Infinium HumanMethylation450 BeadChip in participants in the Women's Health Initiative (WHI; n=804), the Framingham Heart Study (FHS; n=909) and the Bogalusa Heart study (BHS; n=826)...
September 20, 2017: Aging
https://www.readbyqxmd.com/read/28930480/health-facility-staff-training-for-improving-breastfeeding-outcome-a-systematic-review-for-step-2-of-the-baby-friendly-hospital-initiative
#14
Olukunmi O Balogun, Amarjargal Dagvadorj, Jennifer Yourkavitch, Katharina da Silva Lopes, Maiko Suto, Yo Takemoto, Rintaro Mori, Pura Rayco-Solon, Erika Ota
The Baby-Friendly Hospital Initiative (BFHI) implemented through the "Ten Steps to Successful Breastfeeding" has been widely promoted as an intervention that improves breastfeeding rates. Step 2 requires the training of all healthcare staff in skills that are necessary to implement the policy. This systematic review provides evidence about the effect of training healthcare staff in hospitals and birth centers on breastfeeding outcomes. Randomized controlled trials (RCT), quasi-RCT, and controlled before and after (CBA) studies comparing training of healthcare staff on breastfeeding and supportive feeding practices with no training were included in this review...
September 20, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28929932/one-year-health-and-care-costs-after-hip-fracture-for-home-dwelling-elderly-patients-in-norway-results-from-the-trondheim-hip-fracture-trial
#15
Liv Faksvåg Hektoen, Ingvild Saltvedt, Olav Sletvold, Jorunn L Helbostad, Hilde Lurås, Vidar Halsteinli
AIM: The aim of this study was to estimate the one-year health and care costs related to hip fracture for home-dwelling patients aged 70 years and older in Norway, paying specific attention to the status of the patients at the time of fracture and cost differences due to various patient pathways after fracture. METHODS: Data on health and care service provision were extracted from hospital and municipal records and from national registries; data on unit costs were collected from the municipalities, hospital administrations and previously published studies...
December 2016: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28929098/the-degree-of-one-health-implementation-in-the-west-nile-virus-integrated-surveillance-in-northern-italy-2016
#16
REVIEW
Giulia Paternoster, Laura Tomassone, Marco Tamba, Mario Chiari, Antonio Lavazza, Mauro Piazzi, Anna R Favretto, Giacomo Balduzzi, Alessandra Pautasso, Barbara R Vogler
West Nile virus (WNV) is endemic in the Po valley area, Northern Italy, and within the legal framework of the national plan for the surveillance of human vector-borne diseases, WNV surveillance has over time been implemented. The surveillance plans are based on the transdisciplinary and trans-sectorial collaboration between regional institutions involved in public, animal, and environmental health. This integrated surveillance targets mosquitoes, wild birds, humans, and horses and aims at early detecting the viral circulation and reducing the risk of infection in the human populations...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28928316/integrated-brief-tobacco-and-alcohol-cessation-intervention-in-a-primary-health-care-setting-in-karnataka
#17
O T Sabari Sridhar, Pratima Murthy, K V Kishore Kumar
BACKGROUND: Tobacco and alcohol use are important preventable risk factors for noncommunicable diseases and need to be addressed in primary health care. OBJECTIVES: To find the effectiveness of Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST)-based brief intervention for alcohol and tobacco in a primary health-care setting in Karnataka. METHODS: This study was conducted in 2012 where one primary health center (PHC) in Karnataka was an intervention site and other the control site...
September 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28928027/development-of-a-sexual-needs-rehabilitation-framework-in-women-post-spinal-cord-injury-a-study-from-iran
#18
Raziyeh Maasoumi, Fatemeh Zarei, Effat Merghati-Khoei, Taylor Lawson, Seyyed Hasan Emami-Razavi
OBJECTIVE: To develop a sexual needs rehabilitation framework in women post spinal cord injury (SCI) DESIGN: Mixed-methods study SETTING: Brain and Spinal Cord Injury Research Center (BASIR), Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran PARTICIPANTS: Married women with at least one year passed injury INTERVENTION: Not applicable METHODS: This study was designed in three steps; primary needs assessment with quantitative and qualitative methods, prioritizing identified needs by expert panels, and developing framework...
September 16, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28927831/-beyond-the-willing-the-waiting-the-role-of-peer-based-approaches-in-hepatitis-c-diagnosis-treatment
#19
Charles Henderson, Annie Madden, Jenny Kelsall
This commentary seeks to examine the role, value and importance of peer-based programmatic approaches for ensuring the effective roll-out of the new hepatitis C (HCV) treatments among those most affected - that is, people who inject drugs (PWID). The authors examine recent approaches to HCV treatment in Australia including the provision of universal access to the new DAA regimens regardless of acquisition, genotype or severity of disease. These approaches are contextualised within wider global strategies to support HCV elimination as a public health threat by 2030 (WHO, 2016)...
September 15, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28927776/-gluten-is-the-information-available-on-the-internet-valid
#20
T Banti, L Fievet, A Fabre
BACKGROUND: Internet provides easy access to health information, but the quality and validity of this information vary. OBJECTIVES: Evaluate the quality of website structures and the information provided on celiac disease (CD), gluten sensitivity (GS), and wheat allergy (WA). MATERIALS AND METHODS: The websites addressing CD, GS, and WA appearing on the first two pages of Google, Yahoo, and Bing from seven selected queries were investigated...
September 15, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
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