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Fat grafting

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https://www.readbyqxmd.com/read/28719946/cell-assisted-lipotransfer-friend-or-foe-in-fat-grafting-systematic-review-and-meta-analysis
#1
REVIEW
J Laloze, A Varin, J Gilhodes, N Bertheuil, J L Grolleau, J Brie, J Usseglio, L Sensebe, T Filleron, B Chaput
BACKGROUND: Autologous fat grafting is a common procedure for soft-tissue reconstruction but is associated with a graft resorption rate ranging from 20% to 80%. To improve the fat graft survival rate, a new technique, called cell-assisted lipotransfer (CAL), was developed. With CAL, fat is injected along with adipose-derived stromal cells (ASCs) that are assumed to improve fat survival rate. We conducted an evidence-based meta-analysis to evaluate the efficacy and safety of CAL as compared with conventional autologous fat grafting (non-CAL)...
July 18, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28717289/comparison-of-extended-nasolabial-flap-versus-buccal-fat-pad-graft-in-the-surgical-management-of-oral-submucous-fibrosis-a-prospective-pilot-study
#2
Sandeep B Patil, D Durairaj, G Suresh Kumar, D Karthikeyan, D Pradeep
AIM: To evaluate the application of extended nasolabial flap versus buccal fat pad graft in the surgical management of oral submucous fibrosis. SETTINGS AND DESIGN: This prospective study was carried out in the Department of Oral and Maxillofacial Surgery, Tamil Nadu Government Dental College and Hospital, Chennai. MATERIAL AND METHODS: A total of 8 patients (6 men and 2 women) with age range from 21 to 65 years were selected for study. These 8 patients were randomly divided into two groups of four namely group 1 and group 2...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28713978/bone-marrow-mesenchymal-stem-cell%C3%A2-derived-extracellular-vesicles-improve-the-survival-of-transplanted-fat-grafts
#3
He Huang, Shaoqing Feng, Wenjie Zhang, Wei Li, Peng Xu, Xiangsheng Wang, Ai Ai
Autologous fat grafting is a promising surgical technique for soft tissue augmentation, reconstruction and rejuvenation. However, it is limited by the low survival rate of the transplanted fat, due to the slow revascularization of such grafts. Previous studies have demonstrated that bone marrow mesenchymal stem cell‑derived extracellular vesicles (BMSC‑EVs) are proangiogenic. The present study aimed to investigate whether BMSC‑EVs could improve the survival of transplanted fat grafts. Extracellular vesicles were isolated from the supernatant of cultured rat bone marrow mesenchymal stem cells, and characterized by flow cytometry and scanning electron microscopy...
July 14, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28712787/untethering-physiolysis-for-delta-phalanx-longitudinally-bracketed-diaphysis-combined-with-free-fat-interposition-graft
#4
H-J Lee, P-T Kim, I-H Jeon, M F Deslivia, S-J Lee, H-J Kim, J-P Yoon
We report the results of physiolysis of the epiphyseal bracket combined with free fat grafting for the treatment of delta phalanx. Thirteen cases (five patients) were included. Mean patient age was 6.6years (range, 4-9). The patients underwent physiolysis in which the epiphyseal bracket was cut and replaced with a free fat graft. The angle between the long axis of the proximal and distal phalanges and the ratio between the width and length of the affected middle phalanx were evaluated on plain radiographs. The range of motion in the fingers was also evaluated...
July 13, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28702187/procedure-applications-and-outcomes-of-autologous-fat-grafting
#5
REVIEW
Francesco Simonacci, Nicolò Bertozzi, Michele Pio Grieco, Eugenio Grignaffini, Edoardo Raposio
OBJECTIVE: To systematically review the procedure, applications, and outcomes of autologous fat grafting, a promising technique with various clinical applications. PATIENTS AND METHODS: Literature review of publications concerning autologous fat grafting. RESULTS: Since its introduction, lipofilling has become increasingly popular; however, its results are variable and unpredictable. Several modifications have been made to the procedures of fat harvesting, processing, and injecting...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28693983/a-prospective-randomized-study-comparing-centrifugation-and-sedimentation-for-fat-grafting-in-breast-reconstruction
#6
I Sarfati, R F D van la Parra, C A Terem-Rapoport, D Benyahi, C Nos, K B Clough
BACKGROUND: Fat grafting is an efficient method to correct large volumetric defects after mastectomy. There is an ongoing debate regarding the best method of processing the harvested fat before fat grafting. This study aimed to introduce a new MRI model and to compare two fat processing techniques measuring the gain in soft tissue thickness after fat grafting to the chest wall. METHODS: Fifty-one mastectomy patients (one double sided), who required delayed implant reconstruction, with poor skin conditions were proposed fat grafting prior to implant reconstruction...
June 17, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28692516/clinical-application-of-the-pedicled-buccal-fat-pad-flap-in-immediate-reconstruction-of-oral-tissue-defects-in-oral-surgery
#7
Youmei Zhang, Xiaoqiang Zhao, Shuai Fu, Yong Wu
OBJECTIVE: The aim of this study was to present a new immediate reconstructive option for oral tissue defects with a pedicled buccal fat pad flap in oral surgery. MATERIALS AND METHODS: Fifteen cases (10 males, 5 females; mean age: 50 years) suffering from oral tumor and attending the Affiliated Stomatology Hospital of Kunming Medical University were included in this study. All patients underwent immediate repair surgery involving a pedicled buccal fat pad graft in oral surgery, from July 2013 to August 2016...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28691464/parry-romberg-syndrome-and-linear-facial-scleroderma-management-in-pediatric-population
#8
E Segna, V Pucciarelli, G A Beltramini, C Sforza, F J Silvestre, A B Giannì, A Baj
Among all different types of cutaneous scleroderma, Parry Romberg syndrome and linear scleroderma “en coup de sabre” typically involve the visage. Gradual degeneration of the tissues, from the skin up to the bone, is the stigmata of the diseases and the range of clinical manifestations is wide. They typically start during childhood and slowly progress before stabilizing. Considering the gravity of the associated deformity and its impact on facial function and appearance, we strongly advocate a prompt intervention that however must be tailored on paediatric patients...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28686464/the-influence-of-liquids-on-the-mechanical-properties-of-allografts-in-bone-impaction-grafting
#9
David Putzer, Christoph Gert Ammann, Débora Coraça-Huber, Ricarda Lechner, Werner Schmölz, Michael Nogler
Allografts are used to compensate for bone defects resulting from revision surgery, tumor surgery, and reconstructive bone surgery. Although it is well known that the reduction of fat content of allografts increases mechanical properties, the content of liquids with a known grain size distribution has not been assessed so far. The aim of the study was to compare the mechanical properties of dried allografts (DA) with allografts mixed with a saline solution (ASS) and with allografts mixed with blood (AB) having a similar grain size distribution...
July 7, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28684338/midface-rejuvenation-surgery-combining-preperiosteal-midcheek-lift-lower-blepharoplasty-with-orbital-fat-preservation-and-autologous-fat-grafting
#10
H Chatel, B Hersant, R Bosc, S La Padula, J P Meningaud
OBJECTIVE: The aim of this study was to describe a technique for midface rejuvenation combining lower blepharoplasty, midcheek lift and autologous fat transfer. METHODS: All patients who underwent a midface rejuvenation procedure performed by the same surgeon and using a classic subciliary blepharoplasty surgical approach were identified. The technique combined three distinct procedures: lower blepharoplasty with use of a transposition flap of orbital adipose tissue in the medial and central compartment to reduce the subpalpebral bags and attenuate the palpebrojugual sulcus; midcheek lift in the preperiosteal plane with trans-osseous fixation exerting traction on the soft tissues of the cheek along several vectors; autologous fat transfer to offset the loss of volume in the target area...
July 3, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28682021/causes-and-surgical-outcomes-of-lower-eyelid-retraction
#11
Kun Hae Kim, Ji Sun Baek, Saem Lee, Jung Hye Lee, Hye Sun Choi, Sung Joo Kim, Jae Woo Jang
PURPOSE: To investigate the causes of lower eyelid retraction and evaluate the outcomes of various surgical procedures. METHODS: We conducted a retrospective medical record review of patients who underwent lower eyelid retraction surgery performed by a single surgeon at Kim's Eye Hospital between 2006 and 2013. We investigated the causes of lower eyelid retraction, clinical history, characteristics, treatment, and surgical outcomes. Preoperative and postoperative margin reflex distance 2 and inferior scleral show were measured for each eyelid...
July 4, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28678067/reconstruction-of-parotidectomy-and-lateral-skull-base-defects
#12
Caitlin Bertelsen, Changxing Liu, Niels Kokot
PURPOSE OF REVIEW: The purpose of this review is to summarize the options for reconstruction of parotid and lateral skull base defects based on the size and functional requirements of the defect. RECENT FINDINGS: Free grafts with dermal fat or acellular human dermis, superficial musculoaponeurotic system flaps, and sternocleidomastoid flaps have been successful in preventing Frey's syndrome and restoring facial contour defects after superficial and total parotidectomy...
July 3, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28678028/three-dimensional-ultrasound-versus-computerized-tomography-in-fat-graft-volumetric-analysis
#13
Charles Philip Blackshear, Michael Anthony Rector, Natalie Narie Chung, Dre Michael Irizarry, John Stephen Flacco, Elizabeth Anne Brett, Arash Momeni, Gordon Kwanlyp Lee, Michael T Longaker, Derrick C Wan
Studies evaluating fat grafting in mice have frequently used micro-computed tomography (micro-CT) as an accurate radiographic tool to measure longitudinal volume retention without killing the animal. Over the past decade, however, microultrasonography has emerged as an equally powerful preclinical imaging tool. Given their respective strengths in 3-dimensional reconstruction, there is no study to our knowledge that directly compares micro-CT with microultrasound in volumetric analysis. In this study, we compared the performance of micro-CT with microultrasound in the evaluation of adipose tissue graft volume in a murine model...
July 3, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28671889/cell-based-soft-tissue-reconstruction-in-a-hydrogel-scaffold
#14
Charles P Blackshear, John S Flacco, Stephanie M Vistnes, Natalie N Chung, Dre Irizarry, Elizabeth A Brett, Derek J Yen, Arash Momeni, Michael T Longaker, Derrick C Wan
BACKGROUND: Renevia is a hyaluronin-gelatin crosslinked matrix scaffold that has been studied as an alternative to adipose transfer in soft tissue reconstruction. It is designed to emulate the native extracellular matrix environment by supporting stromal vascular fraction (SVF) cell attachment, survival, and proliferation, thus promoting cell-based volume restoration. However, the concentration of incorporated cells for a clinically relevant result has yet to be determined. METHODS: Five experimental groups of seven CD-1 nude immunodeficient mice were given 250 μL grafts of the following composition: 1 million human SVF cells per mL of Renevia scaffold, 6 million human SVF cells per mL scaffold, 12 million human SVF cells per mL scaffold, Renevia scaffold-alone or human adipose tissue-alone...
June 1, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28666883/a-macroporous-heparin-releasing-silk-fibroin-scaffold-improves-islet-transplantation-outcome-by-promoting-islet-revascularisation-and-survival
#15
Duo Mao, Meifeng Zhu, Xiuyuan Zhang, Rong Ma, Xiaoqing Yang, Tingyu Ke, Lianyong Wang, Zongjin Li, Deling Kong, Chen Li
Islet transplantation is considered the most promising therapeutic option with the potential to cure diabetes. However, efficacy of current clinical islet transplantation is limited by long-term graft dysfunction and attrition. We have investigated the therapeutic potential of a silk fibroin macroporous (SF) scaffold for syngeneic islet transplantation in diabetic mice. The SF scaffold was prepared via lyophilisation, which enables incorporation of active compounds including cytokines, peptide and growth factors without compromising their biological activity...
June 27, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28658472/association-of-fat-grafting-with-patient-reported-outcomes-in-postmastectomy-breast-reconstruction
#16
Katelyn G Bennett, Ji Qi, Hyungjin M Kim, Jennifer B Hamill, Edwin G Wilkins, Babak J Mehrara, Jeffrey H Kozlow
Importance: Fat grafting has proven to be a useful adjunct to breast reconstruction for the treatment of contour irregularities and volume deficits, but the proposed US Food and Drug Administration regulations may severely limit the ability of plastic surgeons to continue its use in this clinical context. Objective: To determine whether fat grafting is associated with patient-reported outcomes (PROs) in patients undergoing breast reconstruction. Design, Setting, and Participants: A longitudinal, multicenter, prospective cohort study was conducted between February 1, 2012, and July 31, 2016, at the 11 sites associated with the Mastectomy Reconstruction Outcomes Consortium Study...
June 28, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28658466/fat-grafting-more-than-just-the-hype
#17
Scott T Hollenbeck, E Shelley Hwang
No abstract text is available yet for this article.
June 28, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28658337/immediate-reconstruction-with-autologous-fat-grafting-influence-in-breast-cancerregional-recurrence
#18
Camile Cesa Stumpf, Jorge Villanova Biazus, Fernando Schuh Ângela Erguy Zucatto, Rodrigo Cericatto, José Antônio Crespo Cavalheiro, Andrea Pires Souto Damin, Márcia Portela Melo
Objective: to evaluate local and systemic recurrence of breast cancer in patients submitted to autologous fat grafting in the immediate reconstruction after conservative surgery for breast cancer. Methods: this is a historical cohort study comparing 167 patients submitted to conservative surgery without reconstruction (conservative surgery group) with 27 patients submitted to conservative treatment with immediate graft reconstruction, following the Coleman's technique (lipofilling group)...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28657470/point-of-care-adipose-derived-stromal-vascular-fraction-cell-isolation-and-eptfe-graft-sodding
#19
Stuart K Williams, Marvin E Morris, Paul Kosnik, Kevin D Lye, Gary Gentzkow, Charles B Ross, Amit J Dwivedi, Leigh B Kleinert
Adipose-derived stromal vascular fraction cell populations are being evaluated for numerous clinical applications. The current study evaluated a point of care (POC) technology, the Tissue Genesis "TGI 1000" Cell Isolation System™, to perform an automated isolation of adipose-derived stromal vascular fraction cells to be used in the fabrication of a tissue engineered vascular graft in the operating room. A total of 7 patients were enrolled in this FDA registered Investigational Device Exemption clinical trial and received femoral to tibial expanded polytetrafluoroethylene (ePTFE) bypass grafts to treat peripheral arterial disease...
June 28, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28655389/role-of-dry-lean-body-mass-for-estimation-of-glomerular-filtration-rate-in-kidney-transplant-recipients
#20
Špela Borštnar, Jelka Lindič, Andrej Škoberne, Luka Ležaič, Aljaž Sočan, Aljoša Kandus, Damjan Kovač
BACKGROUND: The use of equations that predict glomerular filtration rate (GFR) in patients with a kidney graft is still a matter of debate. The purpose of this study was to determine the level of accuracy of GFR equations and the relevance of dry lean body mass in the assessment of GFR. METHODS: In a prospective clinical study, 100 patients with a kidney graft were included. Estimated GFR with Modification of Diet in Renal Disease equation (MDRD), Chronic Kidney Disease Epidemiology Collaboration equation (CKD EPI) with serum creatinine concentration (CKD EPI Cr), serum cystatin C concentration (CKD EPI CysC) or both (CKD EPI Cr-CysC), and creatinine clearance calculated with Cockcroft-Gault equation (CG) was compared with GFR measured by 51Cr-EDTA clearance (mGFR 51Cr-EDTA)...
June 28, 2017: Clinical Nephrology
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