keyword
https://read.qxmd.com/read/38627653/efficacy-and-adverse-reactions-of-peripheral-add-multifocal-soft-contact-lenses-in-childhood-myopia-a-meta-analysis
#21
Desheng Song, Wen Qiu, Ting Jiang, Zhijun Chen, Juan Chen
OBJECTIVES: This study aims to compare the efficacy of peripheral add multifocal soft contact lenses (SCLs) (excluding bifocal SCLs) with single vision contact lenses or spectacles in controlling myopia progression. METHOD: A comprehensive literature search was conducted in the Pubmed, EMBASE, Web of Science, and Cochrane Library databases until October 2023. The literature was thoroughly screened based on predetermined eligibility criteria. Pooled odds ratios (ORs) were calculated for dichotomous data and weighted mean differences (WMD) for continuous data...
April 16, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38627651/comparative-efficacy-and-safety-of-all-kinds-of-intraocular-lenses-in-presbyopia-correcting-cataract-surgery-a-systematic-review-and-meta-analysis
#22
JOURNAL ARTICLE
Jinyu Li, Bin Sun, Yuexin Zhang, Yansong Hao, Ze Wang, Chengjiang Liu, Shanhao Jiang
PURPOSE: To assess the efficacy and safety of various intraocular lenses (IOLs), including standard monofocal, bifocal, trifocal, extended depth of focus (EDOF), and enhanced monofocal IOLs, post-cataract surgery through a network meta-analysis. METHODS: A systematic search of PubMed, Cochrane Library, and Web of Science was conducted to identify relevant studies from the past 5 years. Parameters such as binocular visual acuities, spectacle independence, contrast sensitivity (CS), and optical quality were used to evaluate efficacy and safety...
April 16, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38627603/post-click-labeling-enables-highly-accurate-single-cell-analyses-of-glucose-uptake-ex-vivo-and-in-vivo
#23
JOURNAL ARTICLE
Masaki Tsuchiya, Nobuhiko Tachibana, Itaru Hamachi
Cellular glucose uptake is a key feature reflecting metabolic demand of cells in physiopathological conditions. Fluorophore-conjugated sugar derivatives are widely used for monitoring glucose transporter (GLUT) activity at the single-cell level, but have limitations in in vivo applications. Here, we develop a click chemistry-based post-labeling method for flow cytometric measurement of glucose uptake with low background adsorption. This strategy relies on GLUT-mediated uptake of azide-tagged sugars, and subsequent intracellular labeling with a cell-permeable fluorescent reagent via a copper-free click reaction...
April 16, 2024: Communications Biology
https://read.qxmd.com/read/38627373/the-physiological-interactome-of-tcr-like-antibody-therapeutics-in-human-tissues
#24
JOURNAL ARTICLE
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac Woodhouse, Alexander Bujotzek, Christian Klein, Nicola Ternette
Selective binding of TCR-like antibodies that target a single tumour-specific peptide antigen presented by human leukocyte antigens (HLA) is the absolute prerequisite for their therapeutic suitability and patient safety. To date, selectivity assessment has been limited to peptide library screening and predictive modeling. We developed an experimental platform to de novo identify interactomes of TCR-like antibodies directly in human tissues using mass spectrometry. As proof of concept, we confirm the target epitope of a MAGE-A4-specific TCR-like antibody...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627254/local-anesthesia-with-sedation-and-general-anesthesia-for-the-treatment-of-chronic-subdural-hematoma-a-systematic-review-and-meta-analysis
#25
REVIEW
Mariam Ahmed Abdelhady, Ahmed Aljabali, Mohammad Al-Jafari, Ibrahim Serag, Amr Elrosasy, Ahmed Atia, Aya Ehab, Shrouk F Mohammed, Ibraheem M Alkhawaldeh, Mohamed Abouzid
BACKGROUND: Surgery is the primary treatment for chronic subdural hematoma, and anesthesia significantly impacts the surgery's outcomes. A previous systematic review compared general anesthesia to local anesthesia in 319 patients. Our study builds upon this research, analyzing 4,367 cases to provide updated and rigorous evidence. METHODS: We systematically searched five electronic databases: PubMed, Cochrane Library, Scopus, Ovid Medline, and Web of Science, to identify eligible comparative studies...
April 16, 2024: Neurosurgical Review
https://read.qxmd.com/read/38627233/comparative-efficacy-of-exercise-diet-and-or-pharmacological-interventions-on-bmi-ovulation-and-hormonal-profile-in-reproductive-aged-women-with-overweight-or-obesity-a-systematic-review-and-network-meta-analysis
#26
JOURNAL ARTICLE
David Ruiz-González, Iván Cavero-Redondo, Alba Hernández-Martínez, Andrés Baena-Raya, Sonia Martínez-Forte, Signe Altmäe, Ana M Fernández-Alonso, Alberto Soriano-Maldonado
BACKGROUND: The increasing prevalence of obesity worldwide poses a significant threat to reproductive function owing, in part, to hormonal disturbances caused by negative feedback between excess adiposity and the hypothalamic-pituitary-ovarian axis. Consequently, finding the most appropriate strategies to lose weight and improve ovulation in women with overweight or obesity is a clinically relevant matter that needs to be investigated. A comprehensive comparison of the independent and combined efficacy of lifestyle and/or pharmacological interventions on BMI, ovulation, and hormonal profile in women with overweight or obesity at risk of anovulatory infertility would facilitate improving fertility strategies in this population...
April 16, 2024: Human Reproduction Update
https://read.qxmd.com/read/38626653/extracorporeal-vs-conventional-cpr-for-out-of-hospital-cardiac-arrest-a-systematic-review-and-meta-analysis
#27
JOURNAL ARTICLE
Jing-Yi Wang, Yan Chen, Run Dong, Shan Li, Jin-Min Peng, Xiao-Yun Hu, Wei Jiang, Chun-Yao Wang, Li Weng, Bin Du
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) remains a significant cause of mortality and morbidity worldwide. Extracorporeal cardiopulmonary resuscitation (ECPR) is a potential intervention for OHCA, but its effectiveness compared to conventional cardiopulmonary resuscitation (CCPR) needs further evaluation. METHOD: We systematically searched PubMed, Embase, the Cochrane Library, Web of Science, and ClinicalTrials.gov for relevant studies from January 2010 to March 2023...
April 6, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38626224/dimensions-of-patient-centred-care-from-the-perspective-of-patients-and-healthcare-workers-in-hospital-settings-in-sub-saharan-africa-a-qualitative-evidence-synthesis
#28
JOURNAL ARTICLE
Paul K Okeny, Chiara Pittalis, Celina Flocks Monaghan, Ruairi Brugha, Jakub Gajewski
INTRODUCTION: The United States Institute of Medicine defines patient centred care (PCC), a core element of healthcare quality, as care that is holistic and responsive to individual needs. PCC is associated with better patient satisfaction and improved clinical outcomes. Current conceptualizations of PCC are mainly from Europe and North America. This systematic review summarises the perceived dimensions of PCC among patients and healthcare workers within hospitals in sub-Saharan Africa (SSA)...
2024: PloS One
https://read.qxmd.com/read/38625992/dyadic-care-to-improve-postnatal-outcomes-of-birthing-people-and-their-infants-a-scoping-review-protocol
#29
JOURNAL ARTICLE
Courtney C Choy, Molly E McAdow, Julia Rosenberg, Alyssa A Grimshaw, Josefa L Martinez-Brockman
INTRODUCTION: Dyadic care, which is the concurrent provision of care for a birthing person and their infant, is an approach that may improve disparities in postnatal health outcomes, but no synthesis of existing dyadic care studies has been conducted. This scoping review seeks to identify and summarize: 1) dyadic care studies globally, in which the birthing person-infant dyad are cared for together, 2) postnatal health outcomes that have been evaluated following dyadic care interventions, and 3) research and practice gaps in the implementation, dissemination, and effectiveness of dyadic care to reduce healthcare disparities...
2024: PloS One
https://read.qxmd.com/read/38625960/effectiveness-of-acupuncture-in-the-governor-vessel-and-yangming-meridian-for-the-treatment-of-acute-ischemic-stroke-a-systematic-review-and-network-meta-analysis
#30
JOURNAL ARTICLE
Yingqi Xu, Xiuzhen Xie, Pingping Su, Jiashan Wang, Xinxin Luo, Jianli Niu, Zhuqing Jin
BACKGROUND: Acupuncture of the governor vessel and Yangming meridian are widely used in the treatment of acute ischemic stroke (AIS). However, the optimal meridian for acupuncture in the treatment of AIS remains uncertain. PURPOSE: This network meta-analysis study aimed to compare the clinical effectiveness of acupuncture at governor vessel and Yangming meridian in the treatment of AIS. METHODS: All relevant studies published in CNKI, WANFANG, VIP, Sinomed, Cochrane Library, Web of Science, Pub Med, and Embase before January 13, 2024 were systematically retrieved...
2024: PloS One
https://read.qxmd.com/read/38625697/a-scoping-review-of-digital-fabrication-techniques-applied-to-prosthetics-and-orthotics-part-1-of-2-prosthetics
#31
JOURNAL ARTICLE
Ben M Oldfrey, Dafne Z Morgado Ramirez, Mark Miodownik, Matthew Wassall, Nerrolyn Ramstrand, Man S Wong, Jamie Danemayer, Alex Dickinson, Laurence Kenney, Christopher Nester, Edward Lemaire, Hossein Gholizadeth, Laura E Diment, Margaret K Donovan-Hall, Catherine Holloway
BACKGROUND: Traditionally, the manufacture of prostheses is time-consuming and labor-intensive. One possible route to improving access and quality of these devices is the digitalizing of the fabrication process, which may reduce the burden of manual labor and bring the potential for automation that could help unblock access to assistive technologies globally. OBJECTIVES: To identify where there are gaps in the literature that are creating barriers to decision-making on either appropriate uptake by clinical teams or on the needed next steps in research that mean these technologies can continue on a pathway to maturity...
April 16, 2024: Prosthetics and Orthotics International
https://read.qxmd.com/read/38625608/efficacy-of-rtms-combined-with-cognitive-training-in-tbi-with-cognition-disorder-a-systematic-review-and-meta-analysis
#32
REVIEW
Jia Chen, Yuanwei Dong, Hong Guo, Tianyu Zhao, Di Zhang, Song Jin
Post-traumatic brain injury cognitive disorder(PTBICD) is one of the common symptoms of TBI survivors, severely limiting their life and rehabilitation progress. Repetitive transcranial magnetic stimulation (rTMS) has been shown to modulate cognition in a non-invasive manner while there are inconsistencies in previous studies. A comprehensive systematic review of rTMS treatment in patients with PTBICD is warranted. To evaluate the efficacy and safety of rTMS + cognitive training(CT) in enhancing cognitive function among PTBICD patients...
April 16, 2024: Neurological Sciences
https://read.qxmd.com/read/38625584/timing-of-decompression-in-central-cord-syndrome-a-systematic-review-and-meta-analysis
#33
REVIEW
Luchun Xu, Wenqing Zhong, Chen Liu, He Zhao, Yang Xiong, Shibo Zhou, Yukun Ma, Yongdong Yang, Xing Yu
PURPOSE: This study compared the recovery of motor function and the safety of early and delayed surgical intervention in patients with central cord syndrome (CCS). METHODS: PubMed, Embase, Cochrane Library, and Web of Science were employed to retrieve the targeted studies published from inception to February 19, 2023. Comparative studies of early versus delayed surgical decompression in CCS based on American Spinal Injury Association motor score (AMS) recovery, complication rates, and mortality were selected...
April 16, 2024: European Spine Journal
https://read.qxmd.com/read/38625559/anti-angiogenesis-agents-plus-chemoradiotherapy-for-locally-advanced-nasopharyngeal-cancer-a-systematic-review-and-meta-analysis
#34
REVIEW
Xueqing Sun, Youqi Zhu, Yufei Lou, Xinyu Lu, Bo Wang, Dehong Yu, Yilong Guo, Yong Xin
PURPOSE: To evaluate literature evidences about the efficacy and safety of anti-angiogenesis agents plus chemoradiotherapy versus chemoradiotherapy in the treatment of locally advanced nasopharyngeal carcinoma. METHODS: The relevant literature was systematically searched from the date of establishment to April 2023 in PubMed, Embase, Web of Science, The Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Biological Medicine, Wanfang and VIP database...
April 16, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38623834/genetically-encoded-libraries-and-spider-venoms-as-emerging-sources-for-crop-protective-peptides
#35
JOURNAL ARTICLE
Elena Marone Fassolo, Shaodong Guo, Yachen Wang, Stefano Rosa, Volker Herzig
Agricultural crops are targeted by various pathogens (fungi, bacteria, and viruses) and pests (herbivorous arthropods). Antimicrobial and insecticidal peptides are increasingly recognized as eco-friendly tools for crop protection due to their low propensity for resistance development and the fact that they are fully biodegradable. However, historical challenges have hindered their development, including poor stability, limited availability, reproducibility issues, high production costs, and unwanted toxicity...
April 16, 2024: Journal of Peptide Science
https://read.qxmd.com/read/38623777/efficacy-of-interventions-to-improve-cognitive-function-in-adults-with-spinal-cord-injury-a-systematic-review
#36
JOURNAL ARTICLE
Yan Li, Yule Hu, Ilaria Pozzato, Mohit Arora, Jacob Schoffl, Candice McBain, James Middleton, Ashley Craig
Cognitive impairment is a common complication following spinal cord injury (SCI) and imposes a significant negative impact on adjustment, functional independence, physical and mental health, and quality of life. It is unclear whether interventions for cognitive impairment following SCI are effective. A systematic review of controlled trials was performed to evaluate the effect of interventions on cognitive functions in adults with SCI using search engines: Embase, The Cochrane Library, MEDLINE, Scopus, CINAHL, and Web of Science up to December 2023...
April 16, 2024: Journal of Neurotrauma
https://read.qxmd.com/read/38623733/mhealth-based-gamification-interventions-among-men-who-have-sex-with-men-in-the-hiv-prevention-and-care-continuum-systematic-review-and-meta-analysis
#37
REVIEW
Qianqian Luo, Yue Zhang, Wei Wang, Tianyu Cui, Tianying Li
BACKGROUND: In the past few years, a burgeoning interest has emerged in applying gamification to promote desired health behaviors. However, little is known about the effectiveness of such applications in the HIV prevention and care continuum among men who have sex with men (MSM). OBJECTIVE: This study aims to summarize and evaluate research on the effectiveness of gamification on the HIV prevention and care continuum, including HIV-testing promotion; condomless anal sex (CAS) reduction; and uptake of and adherence to pre-exposure prophylaxis (PrEP), postexposure prophylaxis (PEP), and antiretroviral therapy (ART)...
April 15, 2024: JMIR MHealth and UHealth
https://read.qxmd.com/read/38623701/professionally-applied-fluorides-for-preventing-and-arresting-dental-caries-in-low-and-middle-income-countries-systematic-review
#38
JOURNAL ARTICLE
Manori Dhanapriyanka, Shamini Kosgallana, R D F C Kanthi, Prasanna Jayasekara, Thi Minh An Dao, Diep Hong Ha, Loc Do
OBJECTIVES: This systematic review aimed to review the safety and effectiveness of professionally applied fluorides for preventing and arresting dental caries in low- and middle-income countries (LMICs). METHODS: Randomized controlled trials conducted in LMICs, in which professionally applied fluorides were compared with placebo/no treatment/health education only or usual care with a minimum one-year follow-up period, were included. Any topically applied fluoride agents such as sodium fluoride (NaF), acidulated phosphate fluoride, silver diamine fluoride (SDF), and nano silver fluoride (NSF) were included...
April 16, 2024: Journal of Public Health Dentistry
https://read.qxmd.com/read/38623190/wide-transcriptional-outlook-to-uncover-penicillium-expansum-genes-underlying-fungal-incompatible-infection
#39
JOURNAL ARTICLE
Marta de Ramón-Carbonell, Paloma Sánchez-Torres
Pathogenesis of P. expansum involved different processes and one of them is the recognition between pathogen-host, which in the case of P. expansum is preferably pome fruit. In this work, the possible mechanisms connected to host recognition are addressed through the generation of a subtractive library carried out during the incompatible P. expansum -orange interaction in the initial stages of infection. The generated library was analyzed by massive sequencing and bioinformatic analysis. Of the identified genes, a total of 24 were selected for subsequent expression analysis by RT-qPCR in two incompatible interaction situations...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38623114/comparison-of-the-effects-of-lidocaine-and-amiodarone-on-patients-with-cardiac-arrest-a-systematic-review-and-meta-analysis
#40
REVIEW
Tanya Sinha, Ibrahim Reyaz, Roba A Ibrahim, Manisha Guntha, Aung K Zin, Grahitha Chapala, Mohan K Ravuri, Sujith K Palleti
The objective of this study was to compare the impact of amiodarone and lidocaine on survival and neurological outcomes following cardiac arrest. A systematic review of randomized controlled trials (RCTs) as well as cohort and cross-sectional trials was undertaken, adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Potential relevant studies were searched in databases, including PubMed, Embase, Cochrane Library, and Web of Science, from the beginning of databases to February 15, 2024...
March 2024: Curēus
keyword
keyword
21232
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.