keyword
https://read.qxmd.com/read/38657129/nontarget-identification-of-novel-organophosphorus-flame-retardants-and-plasticizers-in-indoor-air-and-dust-from-multiple-microenvironments-in-china
#1
JOURNAL ARTICLE
Ji Yang, Yiming Yao, Xiaoxiao Li, Ana He, Shijie Chen, Yulong Wang, Xiaoyu Dong, Hao Chen, Yu Wang, Lei Wang, Hongwen Sun
The indoor environment is a typical source for organophosphorus flame retardants and plasticizers (OPFRs), yet the source characteristics of OPFRs in different microenvironments remain less clear. This study collected 109 indoor air samples and 34 paired indoor dust samples from 4 typical microenvironments within a university in Tianjin, China, including the dormitory, office, library, and information center. 29 target OPFRs were analyzed, and novel organophosphorus compounds (NOPs) were identified by fragment-based nontarget analysis...
April 24, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38656260/gastrointestinal-decontamination-using-oil-based-solutions-in-patients-with-acute-aluminum-phosphide-poisoning-a-systematic-review-and-meta-analysis
#2
REVIEW
Amal S A F Hafez, Fatma M Elgazzar, Zahraa K Sobh, Ahmad A El-Ebiary
Some studies suggested that gastrointestinal (GIT) decontamination with oil may improve the prognosis of patients who ingested aluminum phosphide (AlP). The aim of this study is to compare the efficacy and safety of gastric lavage with oil-based solutions to any method of gastric decontamination not using oils in patients presenting with acute AlP poisoning. The literature was searched for English-published randomized controlled trials (RCTs) from inception to 16 September 2023. The searched electronic databases included MEDLINE/PubMed, Cochrane Library, Web of Science, Egyptian Knowledge Bank, Scopus, and Google Scholar...
April 24, 2024: Critical Reviews in Toxicology
https://read.qxmd.com/read/38655348/predictive-value-of-machine-learning-for-the-severity-of-acute-pancreatitis-a-systematic-review-and-meta-analysis
#3
JOURNAL ARTICLE
Rui Qian, Jiamei Zhuang, Jianjun Xie, Honghui Cheng, Haiya Ou, Xiang Lu, Zichen Ouyang
BACKGROUND: Predicting the severity of acute pancreatitis (AP) early poses a challenge in clinical practice. While there are well-established clinical scoring tools, their actual predictive performance remains uncertain. Various studies have explored the application of machine-learning methods for early AP prediction. However, a more comprehensive evidence-based assessment is needed to determine their predictive accuracy. Hence, this systematic review and meta-analysis aimed to evaluate the predictive accuracy of machine learning in assessing the severity of AP...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38655340/microbiome-profiling-and-co-metabolism-pathway-analysis-in-cervical-cancer-patients-with-acute-radiation-enteritis
#4
JOURNAL ARTICLE
Chen-Ying Ma, Jing Zhao, Ju-Ying Zhou
BACKGROUND: Intestinal bacteria significantly contribute to the metabolism of intestinal epithelial tissues. As the occurrence and development of radiation enteritis (RE) depend on the "co-metabolism" microenvironment formed by the host and intestinal microbiota, which involves complex influencing factors and strong correlations, ordinary techniques struggle to fully explain the underlying mechanisms. However, given that it is based on systems biology, metabolomics analysis is well-suited to address these issues...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38655140/the-clinical-efficacy-and-safety-of-different-biliary-drainage-in-malignant-obstructive-jaundice-a-meta-analysis
#5
Yanzhao Wang, Xuebo Zhao, Yan She, Qian Kang, Xianxia Chen
BACKGROUND: Currently, percutaneous transhepatic cholangial drainage (PTCD) and endoscopic retrograde cholangiopancreatography (ERCP) are commonly employed in clinical practice to alleviate malignant obstructive jaundice (MOJ). Nevertheless, there lacks a consensus regarding the superiority of either method in terms of efficacy and safety. AIM: To conduct a systematic evaluation of the effectiveness and safety of PTCD and ERCP in treating MOJ, and to compare the therapeutic outcomes and safety profiles of these two procedures...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38654497/evaluating-extended-curettage-and-adjuvant-therapy-against-wide-resection-and-reconstruction-in-the-management-of-distal-radius-giant-cell-tumors-a-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Ishith Seth, Gabriella Bulloch, Bryan Lim, Yi Xie, Nimish Seth, Warren M Rozen, Sally Kiu-Huen Ng
BACKGROUND: The management of distal radius giant cell tumors (GCTs) remains challenging, and the optimal approach is still a matter of debate. This systematic review and meta-analysis aimed to compare the outcomes of extended curettage and wide resection, the mainstays of treatment. METHODS: Medline (via PubMed), Cochrane Library, Web of Science, Google Scholar, ClinicalTrials.gov, and Embase databases were searched for comparative studies that assessed extended curettage with adjuvant therapy and wide resection with reconstruction in patients with GCTs of the distal radius up to April 2023...
April 23, 2024: Hand: Official Journal of the American Association for Hand Surgery
https://read.qxmd.com/read/38654483/the-effect-of-preoperative-mechanical-bowel-preparation-in-paediatric-bowel-surgery-on-postoperative-wound-related-complications-a-meta-analysis
#7
JOURNAL ARTICLE
Meixue Chen, Jin Lin, Dongrong Miao, Xin Yang, Mei Feng, Manli Liu, Lianqing Xu, Qingran Lin
Mechanical bowel preparation (MBP), a routine nursing procedure before paediatric bowel surgery, is widely should in clinical practice, but its necessity remains controversial. In a systematic review and meta-analysis, we evaluated the effect of preoperative MBP in paediatric bowel surgery on postoperative wound-related complications in order to analyse the clinical application value of MBP in paediatric bowel surgery. As of November 2023, we searched four online databases: the Cochrane Library, Embase, PubMed, and Web of Science...
April 2024: International Wound Journal
https://read.qxmd.com/read/38654270/the-effectiveness-of-instrument-assisted-soft-tissue-mobilization-on-range-of-motion-a-meta-analysis
#8
JOURNAL ARTICLE
Sien Tang, Li Sheng, Jinming Xia, Bing Xu, Peiyong Jin
BACKGROUND: To evaluate the effectiveness of instrument-assisted soft tissue mobilization (IASTM) on range of motion (ROM). METHODS: We performed a literature search of the PubMed, Embase, Web of Science, and Cochrane Library databases from inception to December 23, 2023. Randomized controlled trials that compared treatment groups receiving IASTM to controls or IASTM plus another treatment(s) to other treatment(s) among healthy individuals with or without ROM deficits, or patients with musculoskeletal disorders were included...
April 23, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38653629/impact-of-abo-blood-group-on-mortality-in-trauma-patients-a-systematic-review
#9
REVIEW
Andrew Follows, Antonia Round
BACKGROUND: Hemorrhage is a significant cause of death in trauma patients. There is evidence that individuals with blood group O have higher rates of non-traumatic haemorrhage. It has been suggested that blood group O may be associated with higher mortality in trauma, however existing evidence is limited and conflicting. OBJECTIVE: A systematic review was conducted to evaluate the impact of ABO blood group on mortality in trauma patients. METHODS: MEDLINE via OVID, the Cochrane library and grey literature were searched to identify studies investigating the effect of ABO blood group on mortality of trauma patients admitted to hospital...
April 18, 2024: Transfusion and Apheresis Science
https://read.qxmd.com/read/38653162/application-value-of-a-hybrid-tracer-during-sentinel-lymph-node-biopsy-for-head-and-neck-malignancies-a-systematic-review-and-meta-analysis
#10
REVIEW
Bowen Wang, Xingyue Ma, Xiao Zhang, Xiaoyan Zhang, Shuai Guan, Tiepeng Xiao, Xiangjun Li
To address the limitations of conventional sentinel lymph node biopsy (SLNB), a novel hybrid tracer (indocyanine green [ICG]-99m Tc-nanocolloid) has been developed. This meta-analysis aimed to compare the differences between the novel hybrid tracer and conventional methods using ICG or radioisotope (RI) for SLNB in head and neck malignancies. This study was registered in the International Prospective Register of Systematic Reviews (CRD42023409127). PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched...
April 20, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38653004/non-pharmacological-interventions-to-reduce-thirst-in-patients-with-heart-failure-or-hemodialysis-a-systematic-review-and-meta-analysis
#11
REVIEW
Franziska Wefer, Lars Krüger, Nana Waldréus, Sascha Köpke
BACKGROUND: Thirst is a frequent and burdening symptom in many patients, especially in patients with chronic heart failure (CHF) and/or receiving hemodialysis (HD). As drug therapies are not feasible, non-pharmacological strategies are needed to reduce thirst and thirst-related burden. OBJECTIVES: To identify non-pharmacological interventions aiming to reduce thirst in patients with CHF and/ or HD, to describe intervention components, and to evaluate the effectiveness of these interventions...
April 22, 2024: Heart & Lung: the Journal of Critical Care
https://read.qxmd.com/read/38652734/gaussian-accelerated-molecular-dynamics-simulations-facilitate-prediction-of-the-permeability-of-cyclic-peptides
#12
JOURNAL ARTICLE
Nicolas Frazee, Kyle R Billlings, Blake Mertz
Despite their widespread use as therapeutics, clinical development of small molecule drugs remains challenging. Among the many parameters that undergo optimization during the drug development process, increasing passive cell permeability (i.e., log(P)) can have some of the largest impact on potency. Cyclic peptides (CPs) have emerged as a viable alternative to small molecules, as they retain many of the advantages of small molecules (oral availability, target specificity) while being highly effective at traversing the plasma membrane...
2024: PloS One
https://read.qxmd.com/read/38652718/risk-factors-of-central-catheter-bloodstream-infections-in-intensive-care-units-a-systematic-review-and-meta-analysis
#13
JOURNAL ARTICLE
Huayong Huang, Qiaoling Chang, Yanhui Zhou, Li Liao
BACKGROUND: Central catheter bloodstream infections (CRBSI) is a major cause of healthcare-associated infections. However, few factors are generally accepted and some studies have conflicting finding about some factors, possibly caused by limitation associated with an individual study. This study was to identify risk factors for CRBSI in intensive care units. METHODS: We searched the PubMed, Cochrane Library, Web of science and EMBASE databases and the 4 top Chinese-language databases, including WanFang data, China National Knowledge Infrastructure (CNKI), and Chinese Science and Technology Journal Database (VIP), China Biology Medicine disc (CBM) as of July 2023...
2024: PloS One
https://read.qxmd.com/read/38652657/ptvr-a-software-in-python-to-make-virtual-reality-experiments-easier-to-build-and-more-reproducible
#14
JOURNAL ARTICLE
Eric Castet, Jérémy Termoz-Masson, Sebastian Vizcay, Johanna Delachambre, Vasiliki Myrodia, Carlos Aguilar, Frédéric Matonti, Pierre Kornprobst
Researchers increasingly use virtual reality (VR) to perform behavioral experiments, especially in vision science. These experiments are usually programmed directly in so-called game engines that are extremely powerful. However, this process is tricky and time-consuming as it requires solid knowledge of game engines. Consequently, the anticipated prohibitive effort discourages many researchers who want to engage in VR. This paper introduces the Perception Toolbox for Virtual Reality (PTVR) library, allowing visual perception studies in VR to be created using high-level Python script programming...
April 1, 2024: Journal of Vision
https://read.qxmd.com/read/38652490/uncovering-risks-associated-with-smoking-types-and-intensities-in-esophageal-cancer-within-high-prevalence-regions-in-africa-a-comprehensive-meta-analysis
#15
JOURNAL ARTICLE
Gabriel Tchuente Kamsu, Eugene Jamot Ndebia
Tobacco is usually cited among the well-known risk factors of esophageal cancer, nevertheless, the extent of the contribution of the type of smoking and its intensity to the disease has not been comprehensively elucidated in Africa. We searched Medline/PubMed, Embase, Web of Science, Scopus, Cochrane Library, and African Journals Online studies published before September 2023. The quality of the studies was assessed using the Newcastle-Ottawa scale and the funnel plot was used for assessing potential publication bias...
April 23, 2024: Cancer Epidemiology, Biomarkers & Prevention
https://read.qxmd.com/read/38652488/the-prevalence-and-factors-of-posttraumatic-growth-among-nurses-based-on-the-ptgi-a-systematic-review-and-meta-analysis
#16
REVIEW
Li Zeng, Jialin Wang, Guiling Liu, Zhongqing Yuan, Fengxue Yang, Dong Liu, Lan Li, Yihang Peng
BACKGROUND: The urgency and risk of clinical nursing may cause nurses to experience traumatic stress, but it may also lead to posttraumatic growth. However, no study has comprehensively analyzed the prevalence of posttraumatic growth among nurses using a unified outcome measure and a validated assessment tool. AIM: This study aims to systematically assess the prevalence and factors of posttraumatic growth among nurses based on the Posttraumatic Growth Inventory (PTGI)...
April 23, 2024: International Nursing Review
https://read.qxmd.com/read/38652255/scapular-foramina-a-systematic-review-with-meta-analysis-based-on-3316-scapulae
#17
REVIEW
Tomasz Iskra, Martyna Dziedzic, Jakub Wilk, Julia Toppich, Piotr Pisera, Jan Banach, Michał Bonczar, Patryk Ostrowski, Bernard Solewski, Krzysztof Balawender, Jerzy Walocha, Mateusz Koziej
PURPOSE: In the present study, we want to systematize the previous studies on the scapular foramina (SF) and nutrient foramina (NF) with emphasis on the clinical relevance of this topic. Although seemingly not important, radiologists, clinicians and surgeons should be aware of the presence and characteristics of the SF and NF and look out for possible mistakes that may cause harm to the patients during either the diagnostic process or surgery. METHODS: A comprehensive search was conducted in multiple databases, including PubMed, Scopus, Web of Science, Embase, Cochrane Library and Google Scholar...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38652106/endogenous-tagging-using-split-mneongreen-in-human-ipscs-for-live-imaging-studies
#18
JOURNAL ARTICLE
Mathieu C Husser, Nhat P Pham, Chris Law, Flavia R B Araujo, Vincent J J Martin, Alisa Piekny
Endogenous tags have become invaluable tools to visualize and study native proteins in live cells. However, generating human cell lines carrying endogenous tags is difficult due to the low efficiency of homology-directed repair. Recently, an engineered split mNeonGreen protein was used to generate a large-scale endogenous tag library in HEK293 cells. Using split mNeonGreen for large-scale endogenous tagging in human iPSCs would open the door to studying protein function in healthy cells and across differentiated cell types...
April 23, 2024: ELife
https://read.qxmd.com/read/38652021/comparison-of-effectiveness-and-safety-of-molnupiravir-versus-sotrovimab-for-covid-19-a-systematic-review-and-meta-analysis
#19
REVIEW
Bahman Amani, Behnam Amani
BACKGROUND AND AIM: This systematic review and meta-analysis aimed to compare the effectiveness and safety of molnupiravir and sotrovimab in the treatment of patients with coronavirus disease 2019 (COVID-19). METHODS: Cochrane Library, Web of Science, PubMed, medRxiv, and Google Scholar were systematically searched to identify relevant evidence up to December 2023. The risk of bias was assessed using the risk of bias in nonrandomized studies of interventions tool...
April 2024: Immunity, Inflammation and Disease
https://read.qxmd.com/read/38651865/tandem-autologous-hematopoietic-stem-cell-transplantation-for-patients-with-multiple-myeloma-a-systematic-review-and-meta-analysis
#20
REVIEW
Hongtao Li, Yaxin Zheng, Kehai Gao, Chen Tian
To evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of Science and Cochrane Library databases were systematically searched, and 10 eligible studies were included after data extraction and quality evaluation. Meta-analysis showed that compared to single autologous hematopoietic stem cell transplantation, tandem auto-HSCT does not improve OS, EFS or efficacy in MM patients, and may even lead to higher treatment-related mortality (TRM)...
December 2024: Hematology (Amsterdam, Netherlands)
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