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https://www.readbyqxmd.com/read/29232320/the-impact-of-osteoarthritis-on-the-functioning-and-health-status-of-a-low-income-population-an-example-of-a-disability-paradox
#1
Jorge A Esquivel-Valerio, Wendy Marisol Orzua-de la Fuente, Brenda R Vázquez-Fuentes, Mario Alberto Garza-Elizondo, Roberto Negrete-López, Daniel O Treviño-Montes, Rebeca Thelma Martínez-Villarreal, Jaqueline Rodríguez-Amado, Ingris Peláez-Ballestas, Adalberto Loyola-Sánchez
OBJECTIVE: The aim of this study was to measure the impact of osteoarthritis on the functioning and health status of individuals living in a low-income urban community in Mexico. METHODS: We conducted a cross-sectional, community-based study from December 2014 to November 2015, using the Community Oriented Program for Control of Rheumatic Diseases methodology to identify cases of musculoskeletal disease in a sample of adults older than 18 years in Pueblo Nuevo, Apodaca, Mexico...
December 12, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29230307/who-parents-skills-training-pst-programme-for-children-with-developmental-disorders-and-delays-delivered-by-family-volunteers-in-rural-pakistan-study-protocol-for-effectiveness-implementation-hybrid-cluster-randomized-controlled-trial
#2
S U Hamdani, P Akhtar, Zill-E-Huma, H Nazir, F A Minhas, S Sikander, D Wang, C Servilli, A Rahman
Background: Development disorders and delays are recognised as a public health priority and included in the WHO mental health gap action programme (mhGAP). Parents Skills Training (PST) is recommended as a key intervention for such conditions under the WHO mhGAP intervention guide. However, sustainable and scalable delivery of such evidence based interventions remains a challenge. This study aims to evaluate the effectiveness and scaled-up implementation of locally adapted WHO PST programme delivered by family volunteers in rural Pakistan...
2017: Global Mental Health
https://www.readbyqxmd.com/read/29230254/a-cross-lingual-mobile-medical-communication-system-prototype-for-foreigners-and-subjects-with-speech-hearing-and-mental-disabilities-based-on-pictograms
#3
Krzysztof Wołk, Agnieszka Wołk, Wojciech Glinkowski
People with speech, hearing, or mental impairment require special communication assistance, especially for medical purposes. Automatic solutions for speech recognition and voice synthesis from text are poor fits for communication in the medical domain because they are dependent on error-prone statistical models. Systems dependent on manual text input are insufficient. Recently introduced systems for automatic sign language recognition are dependent on statistical models as well as on image and gesture quality...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29229589/the-effect-of-group-support-psychotherapy-delivered-by-trained-lay-health-workers-for-depression-treatment-among-people-with-hiv-in-uganda-protocol-of-a-pragmatic-cluster-randomized-trial
#4
Etheldreda Nakimuli-Mpungu, Seggane Musisi, Kizito Wamala, James Okello, Sheila Ndyanabangi, Ramin Mojtabai, Jean Nachega, Ofir Harari, Edward Mills
BACKGROUND: There is limited information on the effectiveness of task shifting of mental health services in populations with HIV. OBJECTIVE: This trial aims to evaluate the effectiveness of group support psychotherapy delivered by trained lay health workers to persons living with HIV (PLWH) with depression in primary care. METHODS: Thirty eligible primary care health centers across three districts were randomly allocated to have their lay health workers trained to deliver group support psychotherapy (intervention arm) or group HIV education and treatment as usual (control arm) to PLWH with depression...
December 11, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29229208/assessment-and-treatment-at-a-pain-clinic-a-one-year-follow-up-of-patients-with-chronic-pain
#5
Andrea Hållstam, Monika Löfgren, Lina Benson, Christer Svensén, Britt-Marie Stålnacke
BACKGROUND AND AIMS: Pain is one of the most common reasons for patients to seek primary health care. Pain relief is likely to be achieved for patients suffering from acute pain, but for individuals with chronic pain it is more likely that the condition will persist. These patients have the option of being referred to specialised pain clinics. However, the complexity surrounding chronic pain patients is not well studied in these settings. This study aimed to describe patients with chronic pain referred to a pain clinic by using the information submitted during their first visit and one year later and also to identify associations between baseline characteristics and improvements in health-related quality of life in the follow-up...
October 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29227353/epidemiology-of-osteoarthritis-literature-update
#6
Ernest R Vina, C Kent Kwoh
PURPOSE OF REVIEW: The purpose of this review is to highlight recent studies of osteoarthritis epidemiology, including research on prevalence, disease impact, and potential risk factors. RECENT FINDINGS: Osteoarthritis is highly prevalent in the United States and around the globe. It is a leading cause of disability and can negatively impact people's physical and mental well being. Healthcare resources and costs associated with managing the disease can be substantial...
December 8, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/29226604/an-international-qualitative-study-of-functioning-in-autism-spectrum-disorder-using-the-world-health-organization-international-classification-of-functioning-disability-and-health-framework
#7
Soheil Mahdi, Marisa Viljoen, Tamara Yee, Melissa Selb, Nidhi Singhal, Omar Almodayfer, Mats Granlund, Petrus J de Vries, Lonnie Zwaigenbaum, Sven Bölte
This is the third in a series of four empirical studies designed to develop International Classification of Functioning, Disability and Health (ICF) Core Sets for Autism Spectrum Disorder (ASD). The present study aimed to describe functioning in ASD (as operationalized by the ICF) derived from the perspectives of diagnosed individuals, family members, and professionals. A qualitative study using focus groups and semi-structured interviews were conducted with 19 stakeholder groups (N = 90) from Canada, India, Saudi Arabia, South Africa, and Sweden...
December 11, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29226546/small-supernumerary-marker-chromosome-15-and-a-ring-chromosome-15-associated-with-a-15q26-3-deletion-excluding-the-igf1r-gene
#8
András Szabó, Márta Czakó, Kinga Hadzsiev, Balázs Duga, Zsolt Bánfai, Katalin Komlósi, Béla Melegh
Array comparative genomic hybridization is essential in the investigation of chromosomal rearrangements associated with epilepsy, intellectual disability, and dysmorphic features. In many cases deletions, duplications, additional marker chromosomes, and ring chromosomes originating from chromosome 15 lead to abnormal phenotypes. We present a child with epilepsy, cardiac symptoms, severely delayed mental and growth development, behavioral disturbances and characteristic dysmorphic features showing a ring chromosome 15 and a small supernumerary marker chromosome...
December 11, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29226443/lessons-from-analyzing-the-medical-costs-of-civilian-terror-victims-planning-resources-allocation-for-a-new-era-of-confrontations
#9
Eytan Ellenberg, Mark I Taragin, Jay R Hoffman, Osnat Cohen, Daniella Luft-Afik, Zvia Bar-On, Ishay Ostfeld
Policy Points: Across the globe, the threat from terrorist attacks is rising, which requires a careful assessment of long-term medical support. We found 3 major sources of costs: hospital expenditures, mental health services dedicated to acute stress reactions, and ambulatory follow-up. During the first year, most of the costs were related to hospitalization and support for stress relief. During the second year, ambulatory and rehabilitation costs continued to grow. Public health specialists should consider these major components of costs and their evolution over time to properly advise the medical and social authorities on allocating resources for the medical and nonmedical support of civilian casualties resulting from war or terror...
December 2017: Milbank Quarterly
https://www.readbyqxmd.com/read/29223476/fecundity-in-an-infertile-man-with-r-15-a-challenge-to-the-current-paradigm
#10
Hamid Kalantari, Hamideh Karimi, Seyed Navid Almadani, Mostafa Fakhri, Pegah Mokhtari, Hamid Gourabi, Anahita Mohseni Meybodi
Ring chromosome 15 [r(15)] is a rare condition with a mild-to-severe growth failure, mental disabilities, café-au-lait spots, specific facial features, fertility difficulties and other minor dysmorphic stigmata. Of almost 50 affected individuals reported in the literature, none were assessed for the precise breakpoint positioning, which creates uncertainty in defining a specific phenotype for the deleted segment. This study reports for the first time the vertical transmission of r(15) in three consecutive generations of a family, including a subfertile man, his mother and his newborn infant...
November 22, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29222080/the-12-item-self-report-world-health-organization-disability-assessment-schedule-whodas-2-0-administered-via-the-internet-to-individuals-with-anxiety-and-stress-disorders-a-psychometric-investigation-based-on-data-from-two-clinical-trials
#11
Erland Axelsson, Elin Lindsäter, Brjánn Ljótsson, Erik Andersson, Erik Hedman-Lagerlöf
BACKGROUND: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a widespread measure of disability and functional impairment, which is bundled with the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) for use in psychiatry. Administering psychometric scales via the Internet is an effective way to reach respondents and allow for convenient handling of data. OBJECTIVE: The aim was to study the psychometric properties of the 12-item self-report WHODAS 2...
December 8, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29219074/economic-cost-and-quality-of-life-of-family-caregivers-of-schizophrenic-patients-attending-psychiatric-hospitals-in-ghana
#12
Yaw Nyarko Opoku-Boateng, Irene A Kretchy, Genevieve Cecilia Aryeetey, Duah Dwomoh, Sybil Decker, Samuel Agyei Agyemang, Yesim Tozan, Moses Aikins, Justice Nonvignon
BACKGROUND: Low and middle income countries face many challenges in meeting their populations' mental health care needs. Though family caregiving is crucial to the management of severe mental health disabilities, such as schizophrenia, the economic costs borne by family caregivers often go unnoticed. In this study, we estimated the household economic costs of schizophrenia and quality of life of family caregivers in Ghana. METHODS: We used a cost of illness analysis approach...
December 4, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29218006/reduced-levels-of-the-synaptic-functional-regulator-fmrp-in-dentate-gyrus-of-the-aging-sprague-dawley-rat
#13
Roman Smidak, Fernando J Sialana, Martina Kristofova, Tamara Stojanovic, Dragana Rajcic, Jovana Malikovic, Daniel D Feyissa, Volker Korz, Harald Hoeger, Judit Wackerlig, Diana Mechtcheriakova, Gert Lubec
Fragile X mental retardation protein (FMRP) encoded by Fragile X mental retardation 1 (FMR1) gene is a RNA-binding regulator of mRNA translation, transport and stability with multiple targets responsible for proper synaptic function. Epigenetic silencing of FMR1 gene expression leads to the development of Fragile X syndrome (FXS) that is characterized by intellectual disability and other behavioral problems including autism. In the rat FXS model, the lack of FMRP caused a deficit in hippocampal-dependent memory...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29215506/can-early-patient-reported-outcomes-be-used-to-identify-patients-at-risk-for-poor-1-year-health-outcomes-after-lumbar-laminectomy-with-arthrodesis
#14
Taylor E Purvis, Brian J Neuman, Lee H Riley, Richard L Skolasky
STUDY DESIGN: Prospective cohort. OBJECTIVE: Determine 1) between-patient variability in patient-reported outcomes (PROs) at 4 postoperative time points; 2) within-patient correlation of 1-year PROs with PROs at 3 earlier time points; and 3) ability of early PROs to predict 1-year PROs after lumbar laminectomy with arthrodesis. SUMMARY OF BACKGROUND DATA: It is unclear whether early PROs can help identify patients at risk for poor health outcomes...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29215503/minimum-detectable-measurement-difference-mdmd-for-health-related-quality-of-life-hrql-measures-varies-according-age-and-disability-in-adult-spinal-deformity-asd-implications-for-calculating-minimal-clinically-important-difference-mcid
#15
Michael P Kelly, Han Jo Kim, Christopher P Ames, Douglas C Burton, Leah Yacat Carreon, David W Polly, Richard Hostin, Amit Jain, Jeffrey L Gum, Virginie Lafage, Frank J Schwab, Christopher I Shaffrey, Justin S Smith, Shay Bess
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To investigate the minimum detectable measurement difference (MDMD) in the Scoliosis Research Society-22r (SRS-22r) outcomes instrument in adult spinal deformity (ASD) and to evaluate the effect of baseline data on measurable difference. SUMMARY OF BACKGROUND DATA: The minimum clinically important difference (MCID) is the smallest, clinically relevant change observed and has been proposed for the SRS-22r instrument in ASD as 0...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29215496/comparing-health-related-quality-of-life-outcomes-in-patients-undergoing-either-primary-or-revision-anterior-cervical-discectomy-and-fusion
#16
Gregory D Schroeder, Barrett S Boody, Christopher K Kepler, Mark F Kurd, Stephen Silva, Kristen Nicholson, Jefferson R Wilson, Barret I Woods, Kris E Radcliff, D Greg Anderson, Alan S Hilibrand, Alexander R Vaccaro, Jeffery A Rihn
STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVE: Compare HRQOL outcome metrics in patients undergoing primary and revision ACDF. SUMMARY OF BACKGROUND DATA: Anterior cervical discectomy and fusion (ACDF) is associated with significant improvements in health related quality of life (HRQOL) outcome metrics. However, 2.9% of patients per year will develop symptomatic adjacent segment disease and there is a paucity of literature on HRQOL outcomes following revision ACDF...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29211159/social-inequalities-in-limitations-caused-by-chronic-diseases-and-disabilities-in-brazil-the-2013-national-health-survey
#17
Patricia de Moraes Mello Boccolini, Cristina Maria Rabelais Duarte, Miguel Abud Marcelino, Cristiano Siqueira Boccolini
This paper aims to evaluate the association between social inequalities and self-reported limitations for the performance of daily activities caused by chronic diseases or disabilities. The 2013 National Health Survey evaluated a sample of Brazilians with 18+ years. The outcome was that individuals reported that their daily activities were moderately, severely or very severely limited (LIMIT) by one or more chronic diseases, or mental, physical, hearing or motor impairment. The main exposure was the economy class, classified into five categories, ranging from A (richest) to E (poorest)...
November 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29210054/a-comparison-of-dsm-5-and-icd-11-ptsd-prevalence-comorbidity-and-disability-an-analysis-of-the-ukrainian-internally-displaced-person-s-mental-health-survey
#18
M Shevlin, P Hyland, F Vallières, J Bisson, N Makhashvili, J Javakhishvili, M Shpiker, B Roberts
OBJECTIVE: Recently, the American Psychiatric Association (DSM-5) and the World Health Organization (ICD-11) have both revised their formulation of post-traumatic stress disorder (PTSD). The primary aim of this study was to compare DSM-5 and ICD-11 PTSD prevalence and comorbidity rates, as well as the level of disability associated with each diagnosis. METHOD: This study was based on a representative sample of adult Ukrainian internally displaced persons (IDPs: N = 2203)...
December 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29209612/anxiety-and-depression-in-the-portuguese-older-adults-prevalence-and-associated-factors
#19
Rute Dinis de Sousa, Ana Maria Rodrigues, Maria João Gregório, Jaime Da Cunha Branco, Maria João Gouveia, Helena Canhão, Sara Simões Dias
Anxiety and depression in the elderly individuals have been studied around the world, and some authors consider them among the most serious problems faced by modern societies. With recent economic crisis-very important in Southern European countries-isolation, loneliness, and exclusion of the active society, mental problems are probably raising and associated with distinct factors. In this cross-sectional analysis, nested in a longitudinal population-based cohort study, we analyze anxiety and depression prevalence, and their related factors, in a representative cohort of Portuguese seniors...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29209471/general-practitioners-perceptions-on-clinical-management-and-training-needs-regarding-the-healthcare-of-community-dwelling-people-with-intellectual-disability-a-preliminary-survey-in-singapore
#20
Sreedharan Geetha Sajith, Yen-Li Goh, Joshua Marcus Wee
Background: Studies worldwide indicate that people with intellectual disability have high risks of physical and mental morbidities, and poor quality of health care. This study was aimed at determining general practitioners' perceptions on barriers in clinical assessment and training needs with regard to the healthcare of community-dwelling people with intellectual disability. Methods: A survey questionnaire was developed specifically for the study through focus group discussions and a literature review...
November 2017: Korean Journal of Family Medicine
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