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https://www.readbyqxmd.com/read/29666309/hospital-admissions-associated-with-medication-non-adherence-a-systematic-review-of-prospective-observational-studies
#1
Pajaree Mongkhon, Darren M Ashcroft, C Norman Scholfield, Chuenjid Kongkaew
BACKGROUND: Medication non-adherence in ambulatory care has received substantial attention in the literature, but less so as it affects acute care. Accordingly, we aimed to estimate the frequency with which non-adherence to medication contributes to hospital admissions. METHODS: We searched the Cochrane Library, EMBASE, Cumulative Index to Nursing and Allied Health Literature, International Pharmaceutical Abstracts and PubMed (until December 2017) to identify prospective observational studies that examined prevalence rates of hospital admissions associated with medication non-adherence...
April 17, 2018: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29652673/inflammation-and-coronary-artery-disease-from-pathophysiology-to-canakinumab-anti-inflammatory-thrombosis-outcomes-study-cantos
#2
Mahboob Ali, Sameh Girgis, Atif Hassan, Steven Rudick, Richard C Becker
The worldwide prevalence of cardiovascular disease in general and atherosclerotic coronary artery disease in particular is a health and economic concern of unparalleled proportion. Despite a long history of astute observations beginning in 1575 made by Fallopius, followed by those of von Rokatansky, Virchow, Osler, and Ross, and incremental knowledge of the pathobiology of atherosclerosis to include varying stages of inflammation, response to internally and externally mediated vascular injury, and impaired homeostasis, gaps in the field's understanding persist...
April 12, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29644056/lung-ultrasonography-in-end-stage-renal-disease-moving-from-evidence-to-practice-a-narrative-review
#3
Daniel W Ross, Mohammed M Abbasi, Kenar D Jhaveri, Mala Sachdeva, Ilene Miller, Richard Barnett, Mangala Narasimhan, Paul Mayo, Massini Merzkani, Anna T Mathew
Traditionally, point of care ultrasonography in nephrology has been used for renal biopsies and dialysis line placement. However, there is an emerging literature supporting the value of point of care lung ultrasonography in the assessment of volume status for dialysis patients. We conducted a review and identified 12 studies that examined the utility of lung ultrasonography in assessing volume status in patients with end-stage renal disease. We conclude that lung ultrasonography can be used to determine volume status in chronic dialysis patients by identifying lung congestion using the B-line score...
April 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29643075/widespread-changes-in-transcriptome-profile-of-human-mesenchymal-stem-cells-induced-by-two-dimensional-nanosilicates
#4
James K Carrow, Lauren M Cross, Robert W Reese, Manish K Jaiswal, Carl A Gregory, Roland Kaunas, Irtisha Singh, Akhilesh K Gaharwar
Two-dimensional nanomaterials, an ultrathin class of materials such as graphene, nanoclays, transition metal dichalcogenides (TMDs), and transition metal oxides (TMOs), have emerged as a new generation of materials due to their unique properties relative to macroscale counterparts. However, little is known about the transcriptome dynamics following exposure to these nanomaterials. Here, we investigate the interactions of 2D nanosilicates, a layered clay, with human mesenchymal stem cells (hMSCs) at the whole-transcriptome level by high-throughput sequencing (RNA-seq)...
April 11, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29627770/essential-medicines-for-emergency-care-in-africa
#5
Morgan C Broccoli, Jennifer L Pigoga, Mulinda Nyirenda, Lee Wallis, Emilie J Calvello Hynes
OBJECTIVES: Essential medicines lists (EMLs) are efficient means to ensure access to safe and effective medications. The WHO has led this initiative, generating a biannual EML since 1977. Nearly all countries have implemented national EMLs based on the WHO EML. Although EMLs have given careful consideration to many public health priorities, they have yet to comprehensively address the importance of medicines for treating acute illness and injury. METHODS: We undertook a multistep consensus process to establish an EML for emergency care in Africa...
April 7, 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29619337/prevalence-and-prognostic-significance-of-prolonged-qtc-interval-in-emergency-medical-patients-a-prospective-observational-study
#6
Chhagan Lal Birda, Susheel Kumar, Ashish Bhalla, Navneet Sharma, Savita Kumari
Introduction: QTc interval is affected by many factors and prolongation of same may have prognostic significance. A significant number of patients admitted in medical emergency are acutely ill, have multiple comorbidities and are on medications, all of these factors might affect QTc interval and prognosis. Materials and Methods: Single-center, prospective, observational study was carried out on 279 patients of different illnesses recruited from emergency medical services attached to the Department of Internal Medicine at Postgraduate Institute of Medical Education and Research, Chandigarh, India, a tertiary care hospital...
January 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29617989/knowledge-of-venomous-snakes-snakebite-first-aid-treatment-and-prevention-among-clinicians-in-northern-nigeria-a-cross-sectional-multicentre-study
#7
Godpower C Michael, Bukar A Grema, Ibrahim Aliyu, Mohammed A Alhaji, Teslim O Lawal, Haliru Ibrahim, Aminu G Fikin, Fatima S Gyaran, Kennedy N Kane, Thomas D Thacher, Abba K Badamasi, Emmanuel Ogwuche
Background: Snakebite envenoming causes considerable morbidity and mortality in northern Nigeria. The clinician's knowledge of snakebite impacts outcome. We assessed clinicians' knowledge of snakebite envenoming to highlight knowledge and practice gaps for possible intervention to improve snakebite outcomes. Methods: This was a cross-sectional multicentre study of 374 doctors selected from the accident and emergency, internal medicine, family medicine/general outpatient, paediatrics and surgery departments of nine tertiary hospitals in northern Nigeria using a multistage sampling technique...
March 29, 2018: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29615073/advanced-airway-management-in-hoist-and-longline-operations-in-mountain-hems-considerations-in-austere-environments-a-narrative-review-this-review-is-endorsed-by-the-international-commission-for-mountain-emergency-medicine-icar-medcom
#8
REVIEW
Urs Pietsch, Jürgen Knapp, Oliver Kreuzer, Ludwig Ney, Giacomo Strapazzon, Volker Lischke, Roland Albrecht, Patrick Phillips, Simon Rauch
BACKGROUND: Providing sufficient oxygenation and ventilation is of paramount importance for the survival of emergency patients. Therefore, advanced airway management is one of the core tasks for every rescue team. Endotracheal intubation is the gold standard to secure the airway in the prehospital setting. This review aims to highlight special considerations for advanced airway management preceding human external cargo (HEC) evacuations. METHODS: We systematically searched MEDLINE, EMBASE, and PubMed in August 2017 for articles on airway management and ventilation in patients before hoist or longline operation in HEMS...
April 3, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29610713/ultrasound-for-volume-assessment-in-patients-with-shock-effectiveness-of-an-educational-intervention-for-fourth-year-medical-students
#9
Paul Kukulski, Michael Ward, Keme Carter
Objective Shock is a common emergency condition with high morbidity and mortality, and judicious fluid resuscitation can significantly affect outcomes. The use of a bedside echocardiogram and evaluation of the inferior vena cava (IVC) via ultrasound (US) for collapsibility can predict volume status. Additionally, the Association of American Medical Colleges (AAMC) Entrustable Professional Activities (EPA) 10 states that residents need to be able to address a patient with a critical illness, including hypotension, on Day 1 of residency...
January 30, 2018: Curēus
https://www.readbyqxmd.com/read/29607304/neutrophil-to-lymphocyte-ratio-relation-to-sepsis-severity-scores-and-inflammatory-biomarkers-in-patients-with-community-acquired-pneumonia-a-case-series
#10
Nikolaos-Dimitrios Pantzaris, Christina Platanaki, Charalampos Pierrako, Vasilios Karamouzos, Dimitrios Velissaris
Background and Objectives: Neutrophil to lymphocyte ratio (NLR) as calculated from the white cell differential blood count is considered a promising marker for the prognosis of patients with various diseases, including sepsis. This study was designed to assess the possible use of neutrophil-to-lymphocyte ratio in the prediction of survival outcomes in patients with community acquired pneumonia (CAP). A secondary objective was to compare the prognostic accuracy of NLR with the commonly used severity scores of sepsis SOFA, APACHE II and SAPS II...
March 2018: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/29596072/the-speaker-gender-gap-at-critical-care-conferences
#11
Sangeeta Mehta, Louise Rose, Deborah Cook, Margaret Herridge, Sawayra Owais, Victoria Metaxa
OBJECTIVES: To review women's participation as faculty at five critical care conferences over 7 years. DESIGN: Retrospective analysis of five scientific programs to identify the proportion of females and each speaker's profession based on conference conveners, program documents, or internet research. SETTING: Three international (European Society of Intensive Care Medicine, International Symposium on Intensive Care and Emergency Medicine, Society of Critical Care Medicine) and two national (Critical Care Canada Forum, U...
March 28, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29594372/short-term-outcomes-of-heart-failure-patients-with-reduced-and-preserved-ejection-fraction-after-acute-decompensation-according-to-the-final-destination-after-emergency-department-care
#12
Òscar Miró, V Íctor Gil, Francisco Javier Martín-Sánchez, Javier Jacob, Pablo Herrero, Aitor Alquézar, Lluís Llauger, Sira Aguiló, Gemma Martínez, José Ríos, Alberto Domínguez-Rodríguez, Veli-Pekka Harjola, Christian Müller, John Parissis, W Frank Peacock, Pere Llorens
AIMS: To compare short-term outcomes after an episode of acute heart failure (AHF) in patients with reduced and preserved ejection fractions (HFrEF, < 40%; and HFpEF, > 49%; respectively) according to their destinations after emergency department (ED) care. METHODS AND RESULTS: This secondary analysis of the EAHFE Registry (consecutive AHF patients diagnosed in 41 Spanish EDs) investigated 30-day all-cause mortality, in-hospital all-cause mortality, prolonged hospitalisation (> 7 days), and 30-day post-discharge ED revisit due to AHF, all-cause death, and combined endpoint (ED revisit/death) in 5829 patients with echocardiographically documented HFrEF and HfpEF (HFrEF/HFpEF: 1,442/4,387)...
March 28, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29580916/influences-on-intentions-to-place-long-acting-reversible-contraceptives-a-pilot-study-comparing-by-provider-specialty-in-ohio
#13
Charee Thompson, Jane Broecker, Maggie Dade, Kelly Nottingham
STUDY OBJECTIVE: According to the American Academy of Pediatrics (AAP), pediatricians are to counsel and provide LARCs as first-line-of-defense contraceptives because they are the most effective. We wanted to explore positive influences on LARC placement for pediatricians, particularly when compared to providers in other specialties who care for women. DESIGN: Survey methods with data analyzed using analyses of variance and general linear models in statistical software SPSS 24...
March 23, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29579807/council-of-europe-black-sea-area-project-international-cooperation-for-the-development-of-activities-related-to-donation-and-transplantation-of-organs-in-the-region
#14
E Arredondo, M López-Fraga, E Chatzixiros, B Senemaud, P Brezovsky, C Carella, C Ballesté, A Aydin Mehmet, G Tomadze, I Codreanu, A A Sarkissian, M Simeonova, A Nikonenko, V Zota, M P Gómez, M Manyalich, C Bolotinha, A Franca, A N Costa, M-O Ott, K-H Buchheit
BACKGROUND: In 2011, the European Directorate for the Quality of Medicines & Healthcare of the Council of Europe launched a 3-year collaborative project to address the organ shortage and improve access to transplant health services in Council of Europe member states in the Black Sea area (Armenia, Azerbaijan, Bulgaria, Georgia, Moldova, Romania, Turkey, Ukraine, and the Russian Federation) through the development of safe and ethical donation and transplantation programs. OBJECTIVE: Support the development of donation and transplantation programs through close interstate cooperation between national health organizations and relevant stakeholders...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29576403/a-survey-of-wilderness-medicine-analgesia-practice-patterns
#15
Steven G Schauer, Jason F Naylor, Derek J Brown, Robert V Gibbons, Ian Syndergaard, Tracy Cushing
INTRODUCTION: In 2014, the Wilderness Medical Society (WMS) published guidelines for the treatment of acute pain in remote settings. We surveyed wilderness medicine providers on self-reported analgesia prescribing practices. METHODS: We conducted a prospective, anonymous survey. Respondents were recruited from the WMS annual symposium in 2016. All willing attendees were included. RESULTS: During the symposium, we collected a total of 124 surveys (68% response rate)...
March 22, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29575585/clinical-genetic-counselors-an-asset-in-the-era-of-precision-medicine
#16
Catherine A L Wicklund, Debra A Duquette, Amy L Swanson
Trying to predict what genetic counseling will look like in the era of precision medicine is a continuous challenge. According to the National Institutes of Health, precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle. In order to explore the future of genetic counseling practice in this era, this article examines the current genetic counseling practice, internal and external forces that most likely will continue to shape the genetic counseling profession, and discusses the most important aspects of what genetic counselors have to offer in the era of precision medicine...
March 25, 2018: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/29573274/listen-to-the-public-and-fulfil-their-information-interests-translating-vaccine-communication-research-findings-into-guidance-for-regulators
#17
REVIEW
Priya Bahri, Mireia Castillon Melero
Regulatory authorities have a crucial role in communicating about vaccines they license. In terms of content and timing, their communication to the public is usually driven by data on quality, safety and efficacy. However, concerns over safety and vaccine hesitancy have emerged in some communities of various countries, and this demands a new approach to communication, starting with listening to the public debate. Reviewing communication research findings, coming in particular from the cognitive, decision-making and media sciences, constitutes one mechanism of listening and has led the European Union regulatory network to developing guidance about which common concerns and information needs of the public to address through proactive and prepared communication...
March 24, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29564661/the-learning-curve-of-sonographic-inferior-vena-cava-evaluation-by-novice-medical-students-the-pavia-experience
#18
Santi Di Pietro, Francesco Falaschi, Alice Bruno, Tiziano Perrone, Valeria Musella, Stefano Perlini
PURPOSE: The sonographic evaluation of inferior vena cava diameters and its collapsibility-that is also defined as the caval index-has become a popular way to easily obtain a noninvasive estimate of central venous pressure. This is generally considered an easy sonographic task to perform, and according to the American College of Emergency Physicians (ACEP) Guidelines 25 repetitions of this procedure should be sufficient to reach proficiency. However, little is known about the learning process for this sonographic technique...
March 21, 2018: Journal of Ultrasound
https://www.readbyqxmd.com/read/29564546/sports-psychiatry-mental-health-and-mental-disorders-in-athletes-and-exercise-treatment-of-mental-disorders
#19
REVIEW
Andreas Ströhle
Sports psychiatry has developed for the past 3 decades as an emerging field within psychiatry and sports medicine. An International society has been established in 1994 and also national interest groups were implemented, mostly within the national organizations for psychiatry, some also containing the topic of exercise treatment of mental disorders. Where are we now 30 years later? We systematically but also selectively review the medical literature on exercise, sport, psychiatry, mental health and mental disorders and related topics...
March 21, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29562377/ethical-aspects-in-medical-publishing-in-belgium
#20
Tom G Moreels
Medical publishing has become a pivotal aspect of all stages of career development in medicine in Belgium. Publication pressure is therefore present from the stage of the medical student to the level of the head of an academic medical service. This pressure represents a real danger to commit scientific misconduct, ranging from minor missteps to severe fraud. Recent surveys have shown that scientific misconduct and publication fraud represent an important problem in medical publishing, more than in other scientific fields, also in Belgium...
January 2018: Acta Gastro-enterologica Belgica
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