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Frailty

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https://www.readbyqxmd.com/read/28214239/feasibility-and-factor-structure-of-the-frail-scale-in-older-adults
#1
Ivan Aprahamian, Sumika Mori Lin, Claudia Kimie Suemoto, Daniel Apolinario, Natália Oiring de Castro Cezar, Serpui Marie Elmadjian, Wilson Jacob Filho, Mônica Sanches Yassuda
OBJECTIVES: The aim of the present study was to (1) evaluate a geriatric outpatient sample with the FRAIL scale; (2) investigate the psychometric properties of the scale; and (3) characterize different associations of the subdimensions of the scale with demographic and clinical data. DESIGN: Cross-sectional observational study. SETTING: Geriatric outpatient center a university-based hospital in São Paulo, Brazil. PARTICIPANTS: A total of 811 men and women aged 60 years or older evaluated between March 2015 and September 2015...
February 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28213740/predictors-of-institutionalization-among-home-dwelling-older-finnish-people-a-22-year-follow-up-study
#2
Marika Salminen, Jenni Vire, Laura Viikari, Tero Vahlberg, Hannu Isoaho, Aapo Lehtonen, Matti Viitanen, Seija Arve, Sini Eloranta
BACKGROUND: Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS: To examine the effect of predictive factors on institutionalization in home-dwelling 70-year-old people. METHODS: The data were collected in 1991 by the clinical examinations, a postal questionnaire, and an interview from the residents of Turku, Finland, born in 1920 (n = 1032)...
February 17, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28213044/hepatocellular-carcinoma-screening-associated-with-early-tumor-detection-and-improved-survival-among-patients-with-cirrhosis-in-the-united-states
#3
Amit G Singal, Sahil Mittal, Olutola A Yerokun, Chul Ahn, Jorge Marrero, Adam Yopp, Neehar D Parikh, Steve J Scaglione
BACKGROUND: Professional societies recommend hepatocellular carcinoma screening in patients with cirrhosis but high-quality data evaluating its effectiveness to improve early tumor detection and survival in "real world" clinical practice are needed. AIMS: Characterize the association between hepatocellular carcinoma screening and early tumor detection, curative treatment, and overall survival among patients with cirrhosis. METHODS: We performed a retrospective cohort study of patients diagnosed with hepatocellular carcinoma between June 2012 and May 2013 at four health systems in the United States...
February 14, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28210994/factors-related-to-the-quality-of-life-of-older-prisoners
#4
Stefaan De Smet, Liesbeth De Donder, Denis Ryan, Sofie Van Regenmortel, Dorien Brosens, Stijn Vandevelde
PURPOSES: There is evidence of an increasing emphasis on the relevance of the quality of life-paradigm as an outcome measure for clients in geriatric, forensic, as well as correctional care. This paper aims to explore to what extent variables that were categorized according to the main areas of the Good Lives Model ('the self', 'the body' and 'social life') are related to the quality of life domains of older imprisoned offenders. METHODS: Data were collected by means of a structured questionnaire administered in individual interviews with 93 older prisoners aged 60 years and over in 16 prisons of the Dutch-speaking region in Belgium...
February 16, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28210943/faces-of-frailty-in-aging-with-hiv-infection
#5
REVIEW
Marion Thurn, Deborah R Gustafson
PURPOSE OF THE REVIEW: The number of adults who are aging successfully and have HIV infection is increasing. More effective antiretroviral therapy (ART) regimens are preventing individuals infected with HIV from reaching end stages of the HIV infection and developing AIDS (acquired immunodeficiency syndrome). However, even at lower viral loads, chronic HIV infection appears to have consequences on aging processes, including the development of frailty. RECENT FINDINGS: Frailty is a term used to describe vulnerability in aging...
February 16, 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28209749/efficacy-and-safety-of-folfiri-regimen-in-elderly-versus-nonelderly-patients-with-metastatic-colorectal-or-gastric-cancer
#6
Ji-Won Kim, Keun-Wook Lee, Kyu-Pyo Kim, Ju Hyun Lee, Yong Sang Hong, Jeong-Eun Kim, Sun Young Kim, Sook Ryun Park, Byung-Ho Nam, Sang-Hee Cho, Ik-Joo Chung, Young Suk Park, Ho-Suk Oh, Myung-Ah Lee, Hye Jin Kang, Young Iee Park, Eun-Kee Song, Hye Sook Han, Kyu Taeg Lee, Dong Bok Shin, Jung Hun Kang, Dae Young Zang, Jee Hyun Kim, Tae Won Kim
BACKGROUND: Irinotecan-based chemotherapy is a standard backbone of therapy in patients with metastatic colorectal cancer (CRC) or gastric cancer (GC). However, there is still a paucity of information concerning the efficacy and safety of irinotecan-based regimens in elderly patients. PATIENTS AND METHODS: Using the patient cohort (n = 1,545) from the UGT1A1 genotype study, we compared the efficacy and safety between elderly and nonelderly patients with metastatic CRC (n = 934) or GC (n = 611) who received first- or second-line FOLFIRI (irinotecan, leucovorin, and 5-fluorouracil) chemotherapy...
February 16, 2017: Oncologist
https://www.readbyqxmd.com/read/28209370/-singularity-and-frailty-from-the-prediction-to-the-action
#7
Luis Miguel Gutiérrez Robledo
No abstract text is available yet for this article.
February 13, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28209349/frequency-of-and-significance-of-physical-frailty-in-patients-with-heart-failure
#8
Quin E Denfeld, Kerri Winters-Stone, James O Mudd, Shirin O Hiatt, Christopher V Chien, Christopher S Lee
Physical frailty is an important prognostic indicator in heart failure (HF); however, few studies have examined the relation between physical frailty and invasive hemodynamics among adults with HF. The purpose of this study was to characterize physical frailty in HF in relation to invasive hemodynamics. We enrolled 49 patients with New York Heart Association class II to IV HF when participants were scheduled for a right-sided cardiac heart catheterization procedure. Physical frailty was measured according to the "frailty phenotype": shrinking, weakness, slowness, physical exhaustion, and low physical activity...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28209084/the-effect-of-number-of-siblings-on-adult-mortality-evidence-from-swedish-registers-for-cohorts-born-between-1938-and-1972
#9
Anna Baranowska-Rataj, Kieron Barclay, Martin Kolk
Demographic research has paid much attention to the impact of childhood conditions on adult mortality. We focus on one of the key aspects of early life conditions, sibling group size, and examine the causal effect of growing up in a large family on mortality. While previous studies have focused on low- or middle-income countries, we examine whether growing up in a large family is a disadvantage in Sweden, a context where most parents have adequate resources, which are complemented by a generous welfare state...
March 2017: Population Studies
https://www.readbyqxmd.com/read/28204965/prognostic-value-of-simple-frailty-and-malnutrition-screening-tools-in-patients-with-acute-heart-failure-due-to-left-ventricular-systolic-dysfunction
#10
S Sze, J Zhang, P Pellicori, D Morgan, A Hoye, A L Clark
BACKGROUND: Frailty and malnutrition are common in patients with heart failure (HF), and are associated with adverse outcomes. We studied the prognostic value of three malnutrition and three frailty indices in patients admitted acutely to hospital with HF. METHODS: 265 consecutive patients [62% males, median age 80 (interquartile range (IQR): 72-86) years, median NTproBNP 3633 (IQR: 2025-6407) ng/l] admitted with HF between 2013 and 2014 were enrolled. Patients were screened for frailty using the Derby frailty index (DFI), acute frailty network (AFN) frailty criteria, and clinical frailty scale (CFS) and for malnutrition using the geriatric nutritional risk index (GNRI), controlling nutritional status (CONUT) score and prognostic nutritional index (PNI)...
February 15, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28203694/frailty-and-physical-function-in-older-hiv-infected-adults
#11
Fatima Brañas, Zaida Jiménez, Matilde Sánchez-Conde, Fernando Dronda, Juan Carlos López-Bernaldo De Quirós, María J Pérez-Elías, Pilar Miralles, Margarita Ramírez, Ana Moreno, Juan Berenguer, Santiago Moreno
No abstract text is available yet for this article.
February 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28202426/integrated-platform-for-home-services-using-new-products-and-services-for-senior-citizens-call-cnav-carsat-2015
#12
Michel Noguès, Daniel Laune, Delphine Paccard, Anne-Laure Coupet, Justine Millot-Keurinck, Narjis Bototo, Marine Bertrand, Jean Bousquet
This project is part of: i) the risks of ageing prevention policy of the French retirement and occupational health insurance agency of Languedoc Roussillon (Carsat-LR) and ii) the European innovation partnership on active and healthy ageing (EIP on AHA). It aims to support senior citizens who live independently and have been identified at risk of frailty on a social or health level. The purpose is to increase legibility as well as technical and financial access to innovations for vulnerable seniors who are remote from the digital era, through a multiservice user-friendly platform...
February 15, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28200012/frailty-identification-in-the-emergency-department-a-systematic-review-focussing-on-feasibility
#13
Amy Elliott, Louise Hull, Simon Paul Conroy
No abstract text is available yet for this article.
February 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28198967/fall-and-its-association-with-the-frailty-syndrome-in-the-elderly-systematic-review-with-meta-analysis
#14
Jack Roberto Silva Fhon, Rosalina Aparecida Partezani Rodrigues, Wilmer Fuentes Neira, Violeta Magdalena Rojas Huayta, Maria Lucia do Carmo Cruz Robazzi
OBJECTIVE: To analyze the prevalence of falls and frailty syndrome and the association between these two syndromes in the elderly population. METHOD: Systematic review, without restriction of dates, in English, Portuguese and Spanish languages, in the databases PubMed, CINAHL, LILACS and in the SciElo virtual library. The association between both variables was extracted from the studies (Odds Ratio and 95% Confidence Intervals). RESULTS: The review included 19 studies published between 2001 and 2015...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28198946/chronic-pain-in-elderly-caregivers-at-different-levels-of-frailty
#15
Daiene de Morais, Mariélli Terassi, Keika Inouye, Bruna Moretti Luchesi, Sofia Cristina Iost Pavarini
Objective: To determine whether there are differences in the intensity of chronic pain of elderly caregivers who are frail, pre-frail and non-frail. Methods: Quantitative, descriptive and cross-sectional study. The subjects were 187 elderly caregivers evaluated with a Multidimensional Pain Assessment Scale and the Fried Frailty Phenotype Assessment Components. Descriptive and comparative analyzes, Pearson's chi-square test and Kruskal-Wallis test were used. Results: 24...
February 9, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28198733/clinical-relevance-of-sarcopenia-in-chronic-kidney-disease
#16
Ranjani N Moorthi, Keith G Avin
PURPOSE OF REVIEW: In this article, we review sarcopenia in chronic kidney disease (CKD). We aim to present how definitions of sarcopenia from the general population may pertain to those with CKD, its assessment by clinicians and emerging therapies for sarcopenia in CKD. For this review, we limit our description and recommendations to patients with CKD who are not on dialysis. RECENT FINDINGS: Poorer parameters of lean mass, strength and physical function are associated with worsening patient-centered outcomes such as limiting mobility, falls and mortality in CKD; however, the magnitude of these associations are different in those with and without CKD...
February 13, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28196791/use-of-information-and-communication-technologies-among-older-people-with-and-without-frailty-a-population-based-survey
#17
Niina Susanna Keränen, Maarit Kangas, Milla Immonen, Heidi Similä, Heidi Enwald, Raija Korpelainen, Timo Jämsä
BACKGROUND: Use of information and communication technologies (ICT) among seniors is increasing; however, studies on the use of ICT by seniors at the highest risk of health impairment are lacking. Frail and prefrail seniors are a group that would likely benefit from preventive nutrition and exercise interventions, both of which can take advantage of ICT. OBJECTIVE: The objective of the study was to quantify the differences in ICT use, attitudes, and reasons for nonuse among physically frail, prefrail, and nonfrail home-dwelling seniors...
February 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28195361/frailty-and-incident-depression-in-community-dwelling-older-people-results-from-the-elsa-study
#18
Nicola Veronese, Marco Solmi, Stefania Maggi, Marianna Noale, Giuseppe Sergi, Enzo Manzato, A Matthew Prina, Michele Fornaro, André F Carvalho, Brendon Stubbs
OBJECTIVE: Frailty and pre-frailty are two common conditions in the older people, but whether these conditions could predict depression is still limited to a few longitudinal studies. In this paper, we aimed to investigate whether frailty and pre-frailty are associated with an increased risk of depression in a prospective cohort of community-dwelling older people. METHODS: Four thousand seventy-seven community-dwelling men and women over 60 years without depression at baseline were included from the English Longitudinal Study of Ageing...
February 14, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28193571/outcomes-and-utilization-of-postmastectomy-radiotherapy-for-t3n0-breast-cancers
#19
Samual R Francis, Jonathan Frandsen, Kristine E Kokeny, David K Gaffney, Matthew M Poppe
BACKGROUND: The role of postmastectomy radiotherapy (PMRT) for women with pT3N0M0 breast cancer is controversial. We sought to determine the benefit of PMRT in this cohort using the National Cancer Database (NCDB). METHODS: We analyzed women with pT3N0M0 breast cancer who received mastectomy with or without PMRT between 2004 and 2012. We excluded men, women ≤18 years, neoadjuvant or unknown radiation or chemotherapy status, unknown estrogen or progesterone receptor status, unknown surgical margin status, histology other than invasive ductal or lobular carcinoma, and if death occurred <3 months after diagnosis...
February 9, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28190748/modified-frailty-index-associated-with-clavien-dindo-iv-complications-in-robot-assisted-radical-prostatectomies-a-retrospective-study
#20
Isaiah Levy, Mark Finkelstein, Khawaja Hassan Bilal, Michael Palese
OBJECTIVE: To determine the effect of frailty on patient outcomes including any complication, Clavien-Dindo IV (CDIV) (intensive care unit-level) complications, and 30-day mortality for robotic-assisted radical prostatectomies (RARP) patients in comparison to other predictive indices using the modified frailty index (mFI). MATERIAL AND METHODS: Patients undergoing RARP from 2008 to 2014 for a prostate cancer-related diagnosis were queried using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database...
February 9, 2017: Urologic Oncology
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