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https://www.readbyqxmd.com/read/29223975/auras-and-the-risk-of-seizures-with-impaired-consciousness-following-epilepsy-surgery-implications-for-driving
#1
Sam Fairclough, Aidan G O'Keeffe, Jane de Tisi, John S Duncan
OBJECTIVE: To calculate the chance of a seizure in the next year (COSY) for seizures with impaired awareness in those experiencing auras only, those with no seizures and those with continuing seizures. Epilepsy surgery is an effective treatment for refractory focal epilepsy. Driving is an important factor affecting quality of life. In the UK, driving is not permitted if focal seizures with no impairment of awareness (auras, simple partial seizures) continue, if there is a prior history of seizures with impaired awareness, as will invariably be the case in those having epilepsy surgery...
December 9, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29223761/chemsex-risk-behaviours-and-sexually-transmitted-infections-among-men-who-have-sex-with-men-in-dublin-ireland
#2
Ronan W Glynn, Niamh Byrne, Siobhan O'Dea, Adam Shanley, Mary Codd, Eamon Keenan, Mary Ward, Derval Igoe, Susan Clarke
BACKGROUND: Drug use for or during sex ('chemsex') among MSM has caused concern, because of the direct effects of the drugs themselves, and because of an increased risk of transmission of sexually transmitted infections (STIs). This study aimed to assess the prevalence of chemsex, associated behaviours and STIs among attendees at Ireland's only MSM-specific sexual health clinic in Dublin over a six week period in 2016. METHODS: The questionnaire collected demographic data, information on sexuality and sexual practice, self-reported history of treatment for STIs, and chemsex use...
December 7, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29223567/predictive-ability-of-the-evaruci-scale-and-comhon-index-for-pressure-injury-risk-in-critically-ill-patients-a-diagnostic-accuracy-study
#3
M de Los Ángeles Leal-Felipe, M Del Carmen Arroyo-López, M Del Cristo Robayna-Delgado, Ana Gómez-Espejo, Patricia Perera-Díaz, Carmen D Chinea-Rodríguez, Natalia García-Correa, Alejandro Jiménez-Sosa
BACKGROUND: Hospital-acquired pressure injuries are a costly and largely preventable complication occurring in a variety of acute care settings. Patients admitted to the intensive care unit are at greater risk of developing pressure injuries. OBJECTIVE: To determine whether the efficiency of scales to measure pressure injury risk increase when a continuously updated 3-day moving average method is used. METHODS: With a retrospective cohort design we recruited 3085 patients treated between June 2011 and February 2015 in the intensive care unit of a tertiary level university hospital...
December 6, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29222550/tissue-transglutaminase-elevates-intraocular-pressure-in-mice
#4
Urmimala Raychaudhuri, J Cameron Millar, Abbot F Clark
Purpose: Tissue transglutaminase (TGM2) is elevated in glaucomatous trabecular meshwork (TM) tissues. We investigated whether increased expression of TGM2 increases extracellular matrix crosslinking in the TM, thereby increasing aqueous humor outflow resistance and elevating intraocular pressure (IOP) in mouse eyes. Methods: GTM3, primary human GTM 125-05, and cultured mouse TM cells were transduced with adenovirus serotype 5 expressing human transglutaminase 2 (Ad5...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29220702/the-effect-of-subjective-awareness-measures-on-performance-in-artificial-grammar-learning-task
#5
Ivan I Ivanchei, Nadezhda V Moroshkina
Systematic research into implicit learning requires well-developed awareness-measurement techniques. Recently, trial-by-trial measures have been widely used. However, they can increase complexity of a study because they are an additional experimental variable. We tested the effects of these measures on performance in artificial grammar learning study. Four groups of participants were assigned to different awareness measures conditions: confidence ratings, post-decision wagering, decision strategy attribution or none...
December 5, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/29219939/psychometric-evaluation-of-the-chinese-respiratory-distress-observation-scale-on-critically-ill-patients-with-cardiopulmonary-diseases
#6
Ya-Hsiang Chan, Hua-Shan Wu, Chih-Ching Yen, Margaret L Campbell
BACKGROUND: Respiratory distress is a common and distressing experience that strikes most critically ill patients with cardiopulmonary diseases. Now, most dyspnea assessment tools rely on patient's self-report. Only one instrument, the Respiratory Distress Observation Scale (RDOS), is valid for assessing respiratory distress when the patient cannot provide a dyspnea self-report. PURPOSE: The aims of this study were to develop the Chinese version of RDOS through two-way translation and examine its reliability and validity...
December 6, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29218766/risk-of-recurrent-severe-hypoglycemia-remains-associated-with-a-past-history-of-severe-hypoglycemia-up-to-4%C3%A2-years-results-from-a-large-prospective-contemporary-pediatric-cohort-of-the-dpv-initiative
#7
D Pacaud, J M Hermann, B Karges, J Rosenbauer, T Danne, R Dürr, A Herbst, S Lindauer, S Müther, S Pötzsch, K Raile, M Witsch, R W Holl
OBJECTIVES: In a contemporary cohort of youth with type 1 diabetes, we examined the interval between episodes of severe hypoglycemia (SH) as a risk factor for recurrent SH or hypoglycemic coma (HC). METHODS: This was a large longitudinal observational study. Using the DPV Diabetes Prospective follow-up data, we analyzed frequency and timing of recurrent SH (defined as requiring assistance from another person) and HC (loss of consciousness or seizures) in 14 177 youths with type 1 diabetes aged <20 years and at least 5 years of follow-up...
December 8, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/29217811/creating-health-consciousness-among-adolescent-students-an-innovative-initiative
#8
Shridhar Dwivedi, O P Yadava
No abstract text is available yet for this article.
November 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29217366/initially-missed-or-delayed-diagnosis-of-subarachnoid-hemorrhage-a-nationwide-survey-of-contributing-factors-and-outcomes-in-japan
#9
Yasushi Takagi, Hiromu Hadeishi, Yohei Mineharu, Kazumichi Yoshida, Kuniaki Ogasawara, Akira Ogawa, Susumu Miyamoto
BACKGROUND: Subarachnoid hemorrhage (SAH) remains a significant cause of mortality in Japan. The Japan Stroke Society set out to conduct a nationwide survey to identify contributing factors and outcomes of SAH misdiagnosis. METHODS: We initially surveyed 737 training institutes and 1259 departments in Japan between April 2012 and March 2014 for the presence of misdiagnosed SAH. Clinical information was then sought from respondents with a positive misdiagnosis. Information on 579 misdiagnosed cases was collected...
December 4, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29216792/quadriceps-muscle-thickness-changes-in-patients-with-aneurysmal-subarachnoid-hemorrhage-during-the-acute-phase
#10
Masafumi Nozoe, Masashi Kanai, Hiroki Kubo, Miki Kobayashi, Miho Yamamoto, Shinichi Shimada, Kyoshi Mase
Background Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition that often leads to severe disability in relatively young and healthy people. This disability is physical in many aSAH survivors, so muscle dysfunction may be an important factor in the functional level of these patients. Thus, measuring muscle thickness represents a suitable method for determining muscle function in patients with acute aSAH, because the disordered consciousness often experienced during the acute phase causes active movement to be difficult for these patients...
December 8, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29216780/using-cost-analyses-to-inform-health-professions-education-the-economic-cost-of-pre-clinical-failure
#11
Jonathan Foo, Dragan Ilic, George Rivers, Darrell J R Evans, Kieran Walsh, Terry P Haines, Sophie Paynter, Prue Morgan, Stephen Maloney
BACKGROUND: Student failure creates additional economic costs. Knowing the cost of failure helps to frame its economic burden relative to other educational issues, providing an evidence-base to guide priority setting and allocation of resources. The Ingredients Method is a cost-analysis approach which has been previously applied to health professions education research. In this study, the Ingredients Method is introduced, and applied to a case study, investigating the cost of pre-clinical student failure...
December 7, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29215757/hypothalamic-paraventricular-nucleus-neuronal-nitric-oxide-synthase-activity-is-a-major-determinant-of-renal-sympathetic-discharge-in-conscious-wistar-rats
#12
F D McBryde, B H Liu, E V Roloff, S Kasparov, J F R Paton
The paraventricular nucleus of the hypothalamus (PVN) plays a crucial role in cardiovascular and neuroendocrine regulation. Application of nitric oxide donors to the PVN stimulates GABAergic transmission, and may suppress sympathetic nerve activity (SNA) to lower arterial pressure. However, the role of endogenous nitric oxide within PVN in regulating renal SNA chronically remains to be established in conscious animals. To address this, we used our previously established lentiviral vectors to selectively knock down neuronal nitric oxide synthase (nNOS) in the PVN of conscious Wistar rats...
December 7, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29215547/hypnosis-as-an-effective-and-inexpensive-option-to-control-pain-in-transcatheter-ablation-of-cardiac-arrhythmias
#13
Umberto Barbero, Federico Ferraris, Milena Muro, Carlo Budano, Matteo Anselmino, Fiorenzo Gaita
: Supportive care for pain relief and back discomfort during electrophysiology interventions is usually needed in the electrophysiology lab, especially in long-lasting procedures like atrial fibrillation ablation. Although this is usually achieved with conventional pharmacologic anesthesia, hypnosis has recently aroused interest as a reliable tool to complement and possibly enhance conscious sedation. We collected five case of percutaneous arrhythmia ablation in which, after informed consent, hypnosis was performed by nurse anesthetists in the cath lab...
January 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29215409/imaging-of-acquired-demyelinating-syndrome-with-18f-fdg-pet-ct
#14
Caroline Malo-Pion, Raymond Lambert, Jean-Claude Décarie, Sophie Turpin
Acquired demyelinating syndromes include acute disseminated encephalomyelitis, transverse myelitis and may progress to multiple sclerosis (MS). Acute disseminated encephalomyelitis is characterized by impairment of level of consciousness and multifocal neurological deficits and transverse myelitis by back pain, weakness and sphincter dysfunction. Only a few cases of acquired demyelinating syndrome have been imaged with F-FDG PET/CT. We present two such cases.
December 5, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29215136/spontaneous-intracerebral-hemorrhage-as-presentation-of-atypical-central-neurocytoma-the-role-of-angiogenesis-through-the-characterization-of-tumor-endothelial-cells
#15
Giovanni Marfia, Elena Pirola, Stefania Elena Navone, Matteo Beretta, Laura Guarnaccia, Elena Trombetta, Andrea Franzini, Paolo Rampini, Rolando Campanella
A 36-year-old white man presented with sudden-onset headache and rapid deterioration of consciousness. Computer tomography revealed a right capsular intra-parenchimal hemorrhage with an intraventricular component; therefore, emergency surgery was performed. Once the hematoma was evacuated, the cause of the hemorrhage was identified as a tumor mass and it was resected. Histopathological and immunohistochemical examinations of the surgical specimen disclosed a diagnosis of atypical central neurocytoma. By using a protocol recently set up in our laboratory, we succeeded in isolating and propagating, for the first time, human endothelial cells from central neurocytoma (CN-ECs)...
December 7, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/29214825/effects-of-pride-and-regret-on-geriatric-depression-a-cross-cultural-study-with-mixed-methods-approaches
#16
Othelia E Lee, Seungah Ryu
Pride and regret are self-conscious emotions that develop later in life and become a source of emotional struggle. This cross-cultural study examined the effect of the content and intensity of self-conscious emotions on Geriatric Depression Scale (GDS) scores. Among a convenience sample of 234 older adults (130 in the United States and 104 in South Korea), the contents and intensities of both life regrets and pride were examined. Although a greater variety of regrets was cited by Americans, overall Korean respondents reported higher intensity of regret...
January 1, 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/29214021/a-pilot-study-with-early-adolescents-dealing-with-diet-tobacco-and-air-pollution-using-practical-experiences-and-biological-markers
#17
Chiara Marabelli, Elena Munarini, Micaela Lina, Roberto Mazza, Roberto Boffi, Cinzia De Marco, Ario Ruprecht, Giorgia Angellotti, Chiara Veronese, Paolo Pozzi, Eleonora Bruno, Giuliana Gargano, Adalberto Cavalleri, Giulia Garrone, Franco Berrino
Background: Tobacco use and the Western diet are two of the most important and investigated topics in relation to adolescents' health. In addition, air pollution is a crucial subject for future generations. School is a key social environment that should promote healthy behaviors in children and adolescents. In this field many different programs have been conducted, with mixed results and effectiveness. Research data suggest that comprehensive and multicomponent approaches may have a greater effect on tobacco use and diet, especially when integrated into a community-wide approach...
2017: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29213515/rehabilitation-in-severe-memory-deficit-a-case-study
#18
Nariana Mattos Figueiredo Sousa
The term amnesia refers to a pathological state of mind in which memory and learning are affected to a greater extent than other cognitive functions in a patient without altered level of consciousness. The aim of the current study was to describe a case of severe amnesia in a patient during neurological rehabilitation and to report the importance of preserved cognitive functions to compensate for the mnemonic deficit. VJA presented a clinical condition suggestive of encephalopathy due to caloric-protein malnutrition following several abdominal surgical procedures for complicated choledocholithiasis...
April 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213249/skewed-sociolinguistic-awareness-of-a-native-non-standard-dialect-evidence-from-the-cypriot-greek-writing-of-greek-cypriot-students
#19
Ioli Ayiomamitou, Androula Yiakoumetti
Over the last 50 years, sociolinguistic research in settings in which a regional, social, or ethnic non-standard linguistic variety is used alongside the standard variety of the same language has steadily increased. The educational implications of the concomitant use of such varieties have also received a great deal of research attention. This study deals with regional linguistic variation and its implications for education by focusing on the Greek Cypriot educational context. This context is ideal for investigating the linguistic profiles of speakers of proximal varieties as the majority of Greek Cypriots are primarily educated in just one of their varieties: the standard educational variety...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29212999/-a-case-of-hyperammonemia-resulting-from-urinary-tract-infection-caused-by-urease-producing-bacteria-in-a-parkinson-s-disease-patient-with-drug-induced-urinary-retention
#20
Masahiro Yasunishi, Akihiro Koumura, Yuichi Hayashi, Shohei Nishida, Takashi Inuzuka
A 71-year-old woman with a 9-year history of Parkinson's disease was admitted to our hospital emergently because of consciousness disturbance. Her consciousness level was 200 on the Japan coma scale (JCS), and she presented with tenderness and distension of the lower abdomen. Brain computed tomography showed normal findings. Blood tests showed an increased ammonia level (209 μg/dl) with normal AST and ALT levels. We catheterized the bladder for urinary retention. Five hours after admission, the blood ammonia level decreased to 38 μg/dl, and her consciousness level improved dramatically...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
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