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Consciousness

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https://www.readbyqxmd.com/read/28634728/aroma-oil-therapy-in-palliative-care-a-pilot-study-with-physiological-parameters-in-conscious-as-well-as-unconscious-patients
#1
Melanie Goepfert, Patrick Liebl, Natalie Herth, Giancarlo Ciarlo, Jens Buentzel, Jutta Huebner
OBJECTIVE: The aim of this pilot study is to analyze the reactions of healthy test persons and conscious as well as unconscious palliative patients to aroma stimuli. PATIENTS AND METHODS: In a randomized controlled study, healthy probands, conscious and unconscious palliative patients were exposed to two essential oils (lemon, lavender). Water was used as the control stimulus. Physiological parameters (breathing rate and heart rate, oxygen saturation, systolic, diastolic and mean arterial pressure) were measured...
June 20, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28634315/-a-case-of-metastatic-brain-tumor-complicated-by-multiple-repeated-hemorrhages
#2
Kentaro Hayashi, Yukishige Hayashi, Yoshitaka Matsuo, Kiyoshi Shirakawa, Makio Kaminogo
Metastatic brain tumor occasionally results in multiple cerebral hemorrhages. Here, we report a case of metastatic brain tumor complicated by multiple repeated cerebral hemorrhages. An 80-year-old man with a history of removal of lung cancer was admitted to our hospital because of disturbed consciousness following headache. A brain CT revealed a mass lesion of 40-mm diameter in the left cerebellum and a mass lesion of 2-mm diameter in the right temporal lobe. The cerebellar mass lesion showed homogeneous iso-density, indicating a subacute phase hemorrhage...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28633545/late-recovery-of-awareness-in-prolonged-disorders-of-consciousness-a-cross-sectional-cohort-study
#3
Kudret Yelden, Sophie Duport, Leon M James, Agnieszka Kempny, Simon F Farmer, Alex P Leff, E Diane Playford
PURPOSE: To detect any improvement of awareness in prolonged disorders of consciousness in the long term. METHODS: A total of 34 patients with prolonged disorders of consciousness (27 vegetative state and seven minimally conscious state; 16 males; aged 21-73) were included in the study. All patients were initially diagnosed with vegetative/minimally conscious state on admission to our specialist neurological rehabilitation unit. Re-assessment was performed 2-16 years later using Coma Recovery Scale-Revised...
June 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28633263/structural-valve-deterioration-of-a-subcoronary-implanted-stentless-bioprosthesis-how-to-treat
#4
Eva Karolina Harmel, Lenard Conradi, Ulrich Schäfer, Florian Deuschl, Niklas Schofer, Stefan Blankenberg, Hermann Reichenspurner, Evaldas Girdauskas
We present a case of transcatheter valve-in-valve replacement performed because of structural valve deterioration of a subcoronary implanted stentless aortic bioprosthesis. A 23-mm self-expandable transcatheter heart valve (THV) with supraannular seating was chosen. The procedure was performed with the patient under conscious sedation. After anchoring and partial valve deployment, the patient experienced an acute onset of angina. The angiogram showed left main coronary artery obstruction. Prompt resheathing and retrieval of the THV was performed, and the procedure was aborted...
July 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28632897/delving-within-the-new-science-of-the-unconscious
#5
Steve Paulson, Heather A Berlin, Efrat Ginot, George Makari
What exactly is the relationship between conscious awareness and the unconscious mind? How, for example, does the brain classify and sort its different functions into conscious or unconscious processes? How has the history of human conceptualizations about the unconscious influenced current theories? Steve Paulson, executive producer of To the Best of Our Knowledge, moderated a discussion among neuroscientist Heather Berlin, psychologist Efrat Ginot, and psychiatrist George Makari to shed light on the history of the mind and the latest insights into the still emerging science of the unconscious...
June 20, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28632752/learning-to-exploit-a-hidden-predictor-in-skill-acquisition-tight-linkage-to-conscious-awareness
#6
Randy Tran, Harold Pashler
It is often assumed that implicit learning of skills based on predictive relationships proceeds independently of awareness. To test this idea, four groups of subjects played a game in which a fast-moving "demon" made a brief appearance at the bottom of the computer screen, then disappeared behind a V-shaped occluder, and finally re-appeared briefly on either the upper-left or upper-right quadrant of the screen. Points were scored by clicking on the demon during the final reappearance phase. Demons differed in several visible characteristics including color, horn height and eye size...
2017: PloS One
https://www.readbyqxmd.com/read/28632750/renal-sodium-handling-and-blood-pressure-changes-in-gestational-protein-restricted-offspring-role-of-renal-nerves-and-ganglia-neurokinin-expression
#7
Augusto H Custódio, Marcelo C de Lima, Bárbara Vaccari, Patrícia A Boer, José A R Gontijo
BACKGROUND: Considering long-term changes in renal sodium handling and blood pressure in maternal protein-restricted (LP) offspring, we assumed that the development of LP hypertension results from abnormal dorsal root ganglia (DRG) neurokinin expression associated with impaired responsiveness of renal sensory receptors, promoting a reduced urinary excretion of sodium. The present study investigates whether increased blood pressure in protein-restricted offspring would be associated with changes in the DRG cells and in renal pelvic wall expression of NK1R, SP and CGRP when compared to NP offspring...
2017: PloS One
https://www.readbyqxmd.com/read/28632522/relationship-of-reaction-time-to-perception-of-a-stimulus-and-volitionally-delayed-response
#8
Kimford J Meador, Alan Boyd, David W Loring
BACKGROUND AND OBJECTIVE: Initiation of response in a simple reaction time (RT) task may precede conscious perception of the stimulus. Since volitionally delayed responses may require conscious perception of the stimulus before response initiation, it has been hypothesized that volitionally delayed responses will markedly delay RT. METHODS: We conducted two experiments with separate groups of healthy volunteers (n=16; n=13) who performed computerized simple and choice RT tasks...
June 2017: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/28632157/development-of-a-novel-transparent-flexible-capacitive-micromachined-ultrasonic-transducer
#9
Da-Chen Pang, Cheng-Min Chang
This paper presents the world's first transparent flexible capacitive micromachined ultrasonic transducer (CMUT) that was fabricated through a roll-lamination technique. This polymer-based CMUT has advantages of transparency, flexibility, and non-contacting detection which provide unique functions in display panel applications. Comprising an indium tin oxide-polyethylene terephthalate (ITO-PET) substrate, SU-8 sidewall and vibrating membranes, and silver nanowire transparent electrode, the transducer has visible-light transmittance exceeding 80% and can operate on curved surfaces with a 40 mm radius of curvature...
June 20, 2017: Sensors
https://www.readbyqxmd.com/read/28631453/propofol-dexmedetomidine-versus-propofol-remifentanil-conscious-sedation-for-awake-craniotomy-during-epilepsy-surgery
#10
Abd-Elazeem Elbakry, Ezzeldin Ibrahim
BACKGROUND: Conscious sedation during awake craniotomy requires balanced anaesthesia technique to achieve optimum sedation and analgesia. This technique should be done without causing respiratory depression or loss of consciousness. The present study aims at evaluating the effect of propofol-dexmedetomidine versus propofol-remifentanil conscious sedation during awake craniotomy for epilepsy surgery. METHODS: Sixty patients undergoing awake craniotomy for epilepsy surgery were randomly divided into two groups, PD group and PR group...
June 14, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28630882/review-how-do-spontaneous-and-sensory-evoked-activities-interact
#11
REVIEW
Isabelle Ferezou, Thomas Deneux
Twenty years ago, the seminal work of Grinvald et al. revolutionized the view cast on spontaneous cortical activity by showing how, instead of being a mere measure of noise, it profoundly impacts cortical responses to a sensory input and therefore could play a role in sensory processing. This paved the way for a number of studies on the interactions between spontaneous and sensory-evoked activities. Spontaneous activity has subsequently been found to be highly structured and to participate in high cognitive functions, such as influencing conscious perception in humans...
July 2017: Neurophotonics
https://www.readbyqxmd.com/read/28630871/a-systematic-review-and-meta-analysis-on-the-treatment-of-cerebral-hemorrhage-with-naoxueshu-oral-liquid
#12
REVIEW
Lijun Wu, Yanda Li, Xiaofeng Wang, Xiaomeng Ren, Haiyan Zhu, Yikun Sun, Yanwei Xing, Lingqun Zhu, Yonghong Gao, Hongcai Shang
NaoXueShu oral liquid invigorates Qi and promotes blood circulation, which is mainly used for treating the acute stage of the meridian of hemorrhagic apoplexy and acute blood stasis syndrome during early convalescence. Its main clinical manifestations include hemiplegia, mouth askew, hemianesthesia, and inarticulateness. It is used mainly in patients with lobar hemorrhage, basal ganglia, and thalamus of the small amount of bleeding without disturbing consciousness of hypertensive cerebral. The purpose of this study was to evaluate the efficacy and adverse effects of NaoXueShu oral liquid on the treatment of cerebral hemorrhage...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28630413/bayesian-inference-of-physiologically-meaningful-parameters-from-body-sway-measurements
#13
A Tietäväinen, M U Gutmann, E Keski-Vakkuri, J Corander, E Hæggström
The control of the human body sway by the central nervous system, muscles, and conscious brain is of interest since body sway carries information about the physiological status of a person. Several models have been proposed to describe body sway in an upright standing position, however, due to the statistical intractability of the more realistic models, no formal parameter inference has previously been conducted and the expressive power of such models for real human subjects remains unknown. Using the latest advances in Bayesian statistical inference for intractable models, we fitted a nonlinear control model to posturographic measurements, and we showed that it can accurately predict the sway characteristics of both simulated and real subjects...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28630376/functional-connectivity-disturbances-of-the-ascending-reticular-activating-system-in-temporal-lobe-epilepsy
#14
Dario J Englot, Pierre-Francois D'Haese, Peter E Konrad, Monica L Jacobs, John C Gore, Bassel W Abou-Khalil, Victoria L Morgan
OBJECTIVE: Seizures in temporal lobe epilepsy (TLE) disturb brain networks and lead to connectivity disturbances. We previously hypothesised that recurrent seizures in TLE may lead to abnormal connections involving subcortical activating structures including the ascending reticular activating system (ARAS), contributing to neocortical dysfunction and neurocognitive impairments. However, no studies of ARAS connectivity have been previously reported in patients with epilepsy. METHODS: We used resting-state functional MRI recordings in 27 patients with TLE (67% right sided) and 27 matched controls to examine functional connectivity (partial correlation) between eight brainstem ARAS structures and 105 cortical/subcortical regions...
June 19, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28630253/cold-induced-thermogenesis-and-inflammation-associated-cold-seeking-behavior-are-represented-by-different-dorsomedial-hypothalamic-sites-a-three-dimensional-functional-topography-study-in-conscious-rats
#15
Samuel P Wanner, M Camila Almeida, Yury P Shimansky, Daniela L Oliveira, Justin R Eales, Cândido C Coimbra, Andrej A Romanovsky
In the past, we showed that large electrolytic lesions of the dorsomedial hypothalamus (DMH) promoted hypothermia in cold-exposed restrained rats, but attenuated hypothermia in rats challenged with a high dose of bacterial lipopolysaccharide (LPS) in a thermogradient apparatus. The goal of this study was to identify the thermoeffector mechanisms and DMH representation of the two phenomena and, hence, understand how the same lesion could produce two opposite effects on body temperature. We found that the permissive effect of large electrolytic DMH lesions on cold-induced hypothermia was due to suppressed thermogenesis...
June 19, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28630252/alpha-band-brain-oscillations-shape-the-processing-of-perceptible-as-well-as-imperceptible-somatosensory-stimuli-during-selective-attention
#16
Norman Forschack, Till Nierhaus, Matthias M Müller, Arno Villringer
Attention filters and weights sensory information according to behavioral demands. Stimulus-related neural responses are increased for the attended stimulus. Does alpha-band activity mediate this effect and is it restricted to conscious sensory events (suprathreshold), or does it also extend to unconscious stimuli (subthreshold)? To address these questions, we recorded EEG in healthy male and female volunteers undergoing subthreshold and suprathreshold somatosensory electrical stimulation to the left or right index finger...
June 19, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28629735/chronic-fluoxetine-treatment-enhances-sympathetic-activities-associated-with-abnormality-of-baroreflex-function-in-conscious-normal-rats
#17
Ling-Zong Hong, Keh-Feng Huang, Siu-Wan Hung, Li-Te Kuo
Data regarding the effects of selective serotonin reuptake inhibitors (SSRIs), which are a common type of antidepressants, on cardiovascular autonomic function are inconsistent. The present study was conducted to determine the effects of chronic fluoxetine, an SSRI, on blood pressure, cardiac autonomic nervous activities and baroreflex control of heart rate. Male Sprague-Dawley rats were treated with fluoxetine (10mg/kg·day, p.o.) or saline for 14 weeks. Baroreflex function was determined by the sigmoid logistic method based on the heart rate responses to changes in blood pressure elicited by phenylephrine or sodium nitroprusside infusions...
June 16, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28629485/characterisation-of-vitamin-and-mineral-supplement-users-differentiated-according-to-their-motives-for-using-supplements-results-of-the-german-national-nutrition-monitoring-nemonit
#18
Anne Frey, Ingrid Hoffmann, Thorsten Heuer
OBJECTIVE: To characterise German vitamin and mineral supplement users differentiated by their motives for supplement use. DESIGN: Data were obtained from the German National Nutrition Monitoring (2010/11) via two 24 h dietary recalls and a telephone interview. Motive-based subgroups of supplement users were identified by factor and cluster analysis. Sociodemographic, lifestyle, health and dietary characteristics and supplement use were examined. Differences were analysed using χ 2 tests, logistic and linear regression models...
June 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28628161/-detection-and-management-of-the-vascular-paths-in-the-lateral-sinus-wall-using-cone-beam-computed-tomography
#19
(no author information available yet)
OBJECTIVE: To detect the vascular paths in the lateral wall of maxillary sinus using cone beam computer tomography (CBCT), and to retrospect the surgical managements of avoiding bleeding complication during the lateral approach maxillary sinus elevation. METHODS: The documents of 71 consecutive patients with 81 sides maxillary sinus elevation surgery were collected. The vascular paths in the lateral wall of maxillary sinus were detected by the preoperative CBCT, and the messages about the vascular in surgical records were analyzed...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28627763/suspected-methadone-toxicity-from-hospital-to-autopsy-bed
#20
Jaber Gharehdaghi, Asieh Takalloo-Bakhtiari, Hossein Hassanian-Moghaddam, Nasim Zamani, Mohammad-Javad Hedayatshode
High mortality rates have been reported for methadone in both adults and children. We aimed to determine the pattern of toxicity, possible underlying diseases and treatment challenges in patients referred to our center with early diagnosis of methadone toxicity and who later died. Medical files of all methadone-poisoned patients who had been admitted to a referral center of toxicology between March 2011 and March 2016, died during the hospital stay and sent for autopsy to Legal Medicine Organization were retrospectively evaluated...
June 19, 2017: Basic & Clinical Pharmacology & Toxicology
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