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https://www.readbyqxmd.com/read/29475204/time-frequency-features-for-impedance-cardiography-signals-during-anesthesia-using-different-distribution-kernels
#1
Jesús Escrivá Muñoz, Pedro Gambús, Erik W Jensen, Montserrat Vallverdú
OBJECTIVE: This works investigates the time-frequency content of impedance cardiography signals during a propofol-remifentanil anesthesia. MATERIALS AND METHODS: In the last years, impedance cardiography (ICG) is a technique which has gained much attention. However, ICG signals need further investigation. Time-Frequency Distributions (TFDs) with 5 different kernels are used in order to analyze impedance cardiography signals (ICG) before the start of the anesthesia and after the loss of consciousness...
January 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29474404/role-of-acid-sensing-ion-channels-in-hypoxia-and-hypercapnia-induced-ventilatory-responses
#2
Neil D Detweiler, Kenneth G Vigil, Thomas C Resta, Benjimen R Walker, Nikki L Jernigan
Previous reports indicate roles for acid-sensing ion channels (ASICs) in both peripheral and central chemoreception, but the contributions of ASICs to ventilatory drive in conscious, unrestrained animals remain largely unknown. We tested the hypotheses that ASICs contribute to hypoxic- and hypercapnic-ventilatory responses. Blood samples taken from conscious, unrestrained mice chronically instrumented with femoral artery catheters were used to assess arterial O2, CO2, and pH levels during exposure to inspired gas mixtures designed to cause isocapnic hypoxemia or hypercapnia...
2018: PloS One
https://www.readbyqxmd.com/read/29473832/motocross-injuries-in-pediatric-and-adolescent-patients
#3
Amy L McIntosh, Christy M Christophersen
Motocross is a popular sport in which participants ride a two-wheeled, motorized vehicle on an uneven 2-km track with natural or human-made obstacles. Participants compete at high rates of speed, and children as young as age 4 years compete in age-appropriate groups. Motocross is recognized as a strenuous sport with a high accident rate. Most injuries are musculoskeletal in nature. The most commonly injured areas are the forearm, clavicle, femur, and tibia. Many injuries require surgical treatment. Some patients sustain head trauma with loss of consciousness...
March 1, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29470144/the-effect-of-mono-and-diglycerides-on-the-digestion-and-aborption-of-lutein-in-lymph-fistula-rats
#4
Patrick Tso, Mustafa Vurma, Chih-Wei Ko, Dana M Lee, Stephen DeMichele
Breastmilk lutein is better absorbed by infants than lutein delivered in infant formula. Therefore, we wish to better understand the possible absorption differences of lutein in breast milk versus infant formula by determining its bioavailability after gastric administration and whether the intestinal absorption of lutein can be improved by using new delivery vehicles. STUDY ONE compared the intestinal uptake, and the lymphatic and portal transport of lutein in conscious lymph fistula rats. Four groups of lymph and portal vein cannulated rats (n = 8-10/group) were randomized to receive via the gastric tube increasing doses (10,20,40,or 80mg/kg) of 20% lutein in safflower oil (SO) suspension to assess whether there was a saturable level of lutein that can be absorbed and transported in lymph...
February 22, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29468900/health-promotion-in-young-people-identifying-the-predisposing-factors-of-self-care-health-habits
#5
Estefanía Ruiz-Palomino, Cristina Giménez-García, Rafael Ballester-Arnal, María Dolores Gil-Llario
Unhealthy behaviors are strongly associated with chronic diseases, disabilities, or mortality. Identifying the predisposing factors that influence on self-care healthy habits will improve an early detection of high-risk groups. Four hundred and sixty-six Spanish young people aged 18-25 years were assessed. Global perceived health self-care was predicted by Value of health and Conscientiousness, both in females ( R2  = 0.185; F = 29.661; p < 0.001) and males ( R2  = 0.154; F = 17.849; p < 0...
February 1, 2018: Journal of Health Psychology
https://www.readbyqxmd.com/read/29468621/fusarium-brain-abscess-in-a-patient-with-diabetes-mellitus-and-liver-cirrhosis
#6
Yu-Ju Chen, Chao-Liang Chou, Kuan-Ju Lai, Ya-Ju Lin Lin
PURPOSE: Invasive mycosis caused by the Aspergillus, Fusarium, and Mucor can be fetal, especially in the immunocompromised patients with central nervous system (CNS) involvement. Here we present a case of CNS Fusarium infection, and this is the first reported case of Fusarium brain abscess in Taiwan. CASE REPORT: A 65-year-old woman presented with fever and conscious disturbance for 3 days. Neurological examination showed stupor consciousness, neck stiffness, multiple cranial nerves palsy, and bilateral Babinski signs...
September 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29468594/an-ovine-model-for-studying-the-pathophysiology-of-septic-acute-kidney-injury
#7
Yugeesh R Lankadeva, Junko Kosaka, Roger G Evans, Clive N May
The development of acute kidney injury (AKI) is both a significant and independent prognostic factor of mortality in patients with sepsis, but its pathophysiology remains unclear. Herein, we describe an ovine model of sepsis evoked by the administration of live Escherichia coli in which there is hypotension, peripheral vasodilatation with a large increase in cardiac output; a similar hyperdynamic state to that commonly reported in humans. Interestingly, in this sheep model of sepsis, despite an increase in global kidney blood flow, there is a progressive reduction in renal function...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29468588/a-complete-guide-to-using-the-endothelin-1-model-of-stroke-in-conscious-rats-for-acute-and-long-term-recovery-studies
#8
Hima C S Abeysinghe, Carli L Roulston
Multiple methods exist to model permanent and transient ischemia under anesthesia in animals, however most human strokes occur while conscious. The use of endothelin-1 as a vasoconstrictor applied to the perivascular surface of the middle cerebral artery is one of the only methods for inducing stroke in conscious animals. Here, we describe standard operating procedures for stereotaxic placement of an ET-1 guide probe above the middle cerebral artery, induction of stroke in conscious rats, predictive outcome scoring during stroke, and neurological behavioral tests that we use to monitor transient and continuing deficits...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29468584/assessment-of-cardiovascular-function-and-microvascular-permeability-in-a-conscious-rat-model-of-alcohol-intoxication-combined-with-hemorrhagic-shock-and-resuscitation
#9
Travis M Doggett, Jared J Tur, Natascha G Alves, Sarah Y Yuan, Srinivas M Tipparaju, Jerome W Breslin
Hypotension, cardiac depression, and elevated microvascular permeability are known problems that complicate resuscitation of patients following traumatic injury, particularly those who are also intoxicated from alcohol consumption. A conscious rat model of combined alcohol intoxication and hemorrhagic shock has been used to study the hemodynamic mechanisms involved. Here, we describe using this model to study microvascular leakage and cardiac electrical activity.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29467961/the-outcomes-and-prognostic-factors-of-acute-respiratory-failure-in-the-patients-90-years-old-and-over
#10
Wan-Ling Chen, Chin-Ming Chen, Shu-Chen Kung, Ching-Min Wang, Chih-Cheng Lai, Chien-Ming Chao
This retrospective cohort study investigated the outcomes and prognostic factors in nonagenarians (patients 90 years old or older) with acute respiratory failure. Between 2006 and 2016, all nonagenarians with acute respiratory failure requiring invasive mechanical ventilation (MV) were enrolled. Outcomes including in-hospital mortality and ventilator dependency were measured. A total of 173 nonagenarians with acute respiratory failure were admitted to the intensive care unit (ICU). A total of 56 patients died during the hospital stay and the rate of in-hospital mortality was 32...
January 23, 2018: Oncotarget
https://www.readbyqxmd.com/read/29467707/commentary-from-the-phenomenology-to-the-mechanisms-of-consciousness-integrated-information-theory-3-0
#11
COMMENT
Marek Pokropski
No abstract text is available yet for this article.
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29467686/the-role-of-personality-in-daily-food-allergy-experiences
#12
Tamlin S Conner, Miranda Mirosa, Phil Bremer, Rana Peniamina
Food allergies present numerous challenges to coping in everyday life. Even simple things like planning a lunch with a friend can be stressful for people with food allergies. But are some people more adversely impacted by having a food allergy than other people? This paper addressed this question by investigating whether individual differences in the Big Five personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness) are related to food allergy-related problems in everyday life among adults with food allergies...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29467589/cabergoline-induced-pneumocephalus-following-treatment-for-giant-invasive-macroprolactinoma-presenting-with-spontaneous-cerebrospinal-fluid-rhinorrhea
#13
Souha S Elabd, Maswood M Ahmad, Sameer Q Qetab, Mussa Hussain Almalki
Cerebrospinal fluid (CSF) rhinorrhea is rarely reported as the first presenting feature of giant invasive macroprolactinomas. Cerebrospinal fluid rhinorrhea is usually reported as a complication of trauma, neurosurgical, and skull-based procedures (such as pituitary surgery or radiations), and less frequently after medical treatment with dopamine agonists (DAs) for macroprolactinomas. This phenomenon results from fistula creation that communicates between the subarachnoid space and the nasal cavity. Meanwhile, pneumocephalus is another well-recognized complication after transsphenoidal surgery for pituitary macroadenomas...
2018: Clinical Medicine Insights. Endocrinology and Diabetes
https://www.readbyqxmd.com/read/29467036/the-living-dead-perception-of-persons-in-the-unresponsive-wakefulness-syndrome-in-germany-compared-to-the-usa
#14
Inga Steppacher, Johanna Kissler
BACKGROUND: The extent to which people ascribe mind to others has been shown to predict the extent to which human rights are conferred. Therefore, in the context of disorders of consciousness (DOC), mind ascription can influence end of life decisions. A previous US-American study indicated that participants ascribed even less mind to patients with unresponsive-wakefulness-syndrome (UWS) than to the dead. Results were explained in terms of implicit dualism and religious beliefs, as highly religious people ascribed least mind to UWS...
February 21, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29467022/recovery-of-muscle-function-after-deep-neuromuscular-block-by-means-of-diaphragm-ultrasonography-and-adductor-of-pollicis-acceleromyography-with-comparison-of-neostigmine-vs-sugammadex-as-reversal-drugs-study-protocol-for-a-randomized-controlled-trial
#15
Iacopo Cappellini, Fabio Picciafuochi, Daniele Ostento, Ginevra Danti, Angelo Raffaele De Gaudio, Chiara Adembri
BACKGROUND: The extensive use of neuromuscular blocking agents (NMBAs) during surgical procedures still leads to potential residual paralyzing effects in the postoperative period. Indeed, neuromuscular monitoring in an intra-operative setting is strongly advocated. Acetylcholinesterase inhibitors can reverse muscle block, but their short half-life may lead to residual curarization in the ward, especially when intermediate or long-acting NMBAs have been administered. Sugammadex is the first selective reversal drug for steroidal NMBAs; it has been shown to give full and rapid recovery of muscle strength, thus minimizing the occurrence of residual curarization...
February 21, 2018: Trials
https://www.readbyqxmd.com/read/29466713/daily-maternal-separations-during-stress-hyporesponsive-period-decrease-the-thresholds-of-panic-like-behaviors-to-electrical-stimulation-of-the-dorsal-periaqueductal-gray-of-the-adult-rat
#16
Ana Cristina Borges-Aguiar, Luana Zanoni Schauffer, Edo Ronald de Kloet, Luiz Carlos Schenberg
The present study examined whether early life maternal separation (MS), a model of childhood separation anxiety, predisposes to panic at adulthood. For this purpose, male pups were submitted to 3-h daily maternal separations along postnatal (PN) days of either the 'stress hyporesponsive period' (SHRP) from PN4 to PN14 (MS11) or throughout lactation from PN2 to PN21 (MS20). Pups were further reunited to conscious (CM) or anesthetized (AM) mothers to assess the effect of mother-pup interaction upon reunion. Controls were subjected to brief handling (15 s) once a day throughout lactation (BH20)...
February 18, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29466427/endothelial-mineralocorticoid-receptor-ablation-does-not-alter-blood-pressure-kidney-function-or-renal-vessel-contractility
#17
Sidsel B Laursen, Stine Finsen, Niels Marcussen, Susan E Quaggin, Pernille B L Hansen, Henrik Dimke
Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated. We hypothesized that lack of MR in EC may be protective in renal vasculature and examined this by ablating the Nr3c2 gene in endothelial cells (EC-MR) in mice. Blood pressure, heart rate and PAH clearance were measured using indwelling catheters in conscious mice. The role of the MR in EC on contraction and relaxation was investigated in the renal artery and in perfused afferent arterioles...
2018: PloS One
https://www.readbyqxmd.com/read/29465211/-case-report-pneumocephalia-after-epidural-anesthesia-for-hip-replacement-surgery
#18
S A Pervukhin, A M Ageenko, M N Lebedeva, R I Golikov
Lumbar epidural anesthesia is a commonly used anaesthetic technique for trauma and orthopedic surgery of the lower extremities. One of the rare complications of epidural anesthesia is pneumocephalia. The article describes a case of pneumocephalia after epidural anesthesia performed for anesthetic management of the hip replacement surgery. Eight hours after the epidural anesthesia the patient had depression of consciousness progressing to coma. Computed tomog- raphy of the brain detected pneumocephalia. Symptomatic treatment provided a regression of neurological deficit...
September 2017: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/29465200/-the-choice-of-tracheal-intubation-method-in-reconstructive-maxillo-facial-surgery-with-difficult-airways
#19
A Yu Zaytcev, K V Dubrovin, V A Svetlov
BACKGROUND: The development of modern video - and endoscopic equipment allows for revision and adjust to modern protocols for maintaining patency of the difficult airway, especially in maxillofacial or ENT -surgery. THE PURPOSE OF THE STUDY: Comparison the efficacy ofvarious methods of maintaining the airway patency in the practice of reconstructive maxillofacial surgery. MATERIALS AND METHODS: 89 patients, who were divided into 4 groups, were examined...
September 2017: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/29464762/kpr-2579-a-novel-trpm8-antagonist-inhibits-acetic-acid-induced-bladder-afferent-hyperactivity-in-rats
#20
Naoki Aizawa, Yoshikazu Fujimori, Jun-Ichi Kobayashi, Osamu Nakanishi, Hideaki Hirasawa, Haruki Kume, Yukio Homma, Yasuhiko Igawa
AIMS: Transient receptor potential melastatin 8 (TRPM8) is proposed to be a promising therapeutic target for hypersensitive bladder disorders. We examined the effects of KPR-2579, a novel selective TRPM8 antagonist, on body temperature and on mechanosensitive bladder single-unit afferent activities (SAAs) provoked by intravesical acetic acid (AA) instillation in rats. METHODS: Female Sprague-Dawley rats were used. Effects of cumulative intravenous (i.v.) administrations of KPR-2579 (0...
February 21, 2018: Neurourology and Urodynamics
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