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Catheter related infections

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https://www.readbyqxmd.com/read/29027067/human-heterologous-liver-cells-transiently-improve-hyperammonemia-and-ureagenesis-in-individuals-with-severe-urea-cycle-disorders
#1
Jochen Meyburg, Thomas Opladen, Ute Spiekerkötter, Andrea Schlune, Jens-Peter Schenk, Jan Schmidt, Jürgen Weitz, Jürgen Okun, Friederike Bürger, Tawfeg Ben Omran, Ghassan Abdoh, Hilal Al Rifai, Ahmad Monavari, Vassiliki Konstantopoulou, Stefan Kölker, Marc Yudkoff, Georg F Hoffmann
BACKGROUND: Urea cycle disorders (UCDs) still have a poor prognosis despite several therapeutic advancements. As liver transplantation can provide a cure, liver cell therapy (LCT) might be a new therapeutic option in these patients. METHODS: Twelve patients with severe UCDs were included in this prospective clinical trial. Patients received up to six infusions of cryopreserved human heterologous liver cells via a surgically placed catheter in the portal vein. Portal vein pressure, portal vein flow, and vital signs were monitored continuously...
October 12, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29026535/clinical-and-molecular-characteristics-risk-factors-and-outcomes-of-carbapenem-resistant-klebsiella-pneumoniae-bloodstream-infections-in-the-intensive-care-unit
#2
Xia Zheng, Jian-Feng Wang, Wang-Lan Xu, Jun Xu, Juan Hu
BACKGROUND: To analyze the clinical characteristics and outcomes of carbapenem-resistant Klebsiella pneumoniae (CRKp) and carbapenem-susceptible K. pneumoniae (CSKp) bloodstream infections (BSIs), and to study the risk factors for development of CRKp BSI and K. pneumoniae BSI-related mortality. METHODS: A retrospective case control study of patients with K. pneumoniae BSI was conducted in the intensive care unit of the First Affiliated Hospital, Medical of College, Zhejiang University from January 2013 to December 2014...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29025526/hospital-acquired-urinary-tract-infections-results-of-a-cohort-study-performed-in-an-internal-medicine-department
#3
Maria João Lobão, Paulo Sousa
INTRODUCTION: Urinary tract infections are the most frequent healthcare associated infections, being related to both high costs and morbidity. Our intention was to carry out an epidemiological characterization of hospital acquired urinary tract infections that occurred in an internal medicine department of a Portuguese hospital. MATERIAL AND METHODS: Retrospective cohort study (historic cohort). Data were analysed from a systematic random sample of 388 patients, representative of the 3492 admissions occurred in 2014 in that department...
September 29, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29023196/home-parenteral-nutrition-vascular-access-and-related-complications
#4
Martyn Dibb, Simon Lal
Patients with chronic intestinal failure are dependent on parenteral nutrition (PN) to maintain health and preserve life. Maintaining safe vascular access is vital to prevent life-threatening complications such as catheter-related bloodstream infection or central venous occlusion. Dedicated central venous catheters with rigorous catheter care aseptic protocols are vital in obtaining good long-term outcomes that allow continuation of PN over many years. Good catheter care requires an experienced multidisciplinary team using appropriate vascular devices, trained to identify and aggressively treat catheter-related bloodstream infections, catheter occlusions, and catheter-related thrombosis...
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29020942/peripherally-inserted-central-catheter-related-bloodstream-infection-due-to-tsukamurella-pulmonis-a-case-report-and-literature-review
#5
Jun Suzuki, Teppei Sasahara, Masaki Toshima, Yuji Morisawa
BACKGROUND: Tsukamurella pulmonis is an aerobic gram-positive and rod-shaped organism that causes central catheter-related bloodstream infections in immunocompromised hosts. However, peripherally inserted central catheter (PICC)-related bloodstream infections due to this organism have not been reported. CASE PRESENTATION: We describe a case of a 48-year-old man with acquired immunodeficiency syndrome and diffuse large B cell lymphoma who received five courses of chemotherapy including rituximab , cyclophosphamide , doxorubicin hydrochloride , vincristine , and prednisone via a PICC...
October 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29020252/short-term-peripheral-venous-catheter-related-bloodstream-infections-a-systematic-review
#6
Leonard A Mermel
Short-term peripheral venous catheters (PVCs) are commonly used in healthcare settings. To determine the magnitude of bloodstream infections (BSIs) related to their use, PubMed, article bibliographies, and the authors' library were searched for pertinent articles. The incidence of PVC-related BSIs was 0.18% among 85063 PVCs. Short-term PVCs accounted for a mean of 6.3% and 23% of nosocomial BSIs and nosocomial catheter-related BSIs, respectively. Prolonged dwell time and catheter insertion under emergent conditions increased risk of PVC-related bloodstream infection (PVCR-BSI)...
August 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29019759/non-catheter-related-venous-thromboembolism-in-children-imaging-review-from-head-to-toe
#7
Mougnyan Cox, Monica Epelman, Tushar Chandra, Arthur B Meyers, Craig M Johnson, Daniel J Podberesky
Non-catheter-related venous thromboembolism (VTE) is less common in children than in adults. Although the presence of a central venous catheter is the most common cause of venous thrombosis in children, infection and inflammation, malignancy, hypercoagulability, dehydration, and certain sites of normal variant and pathologic anatomic narrowing all predispose to VTE in children. The mortality and morbidity of VTE vary according to the underlying cause, including whether malignancy is present. Various modalities including ultrasonography (US), computed tomography, and magnetic resonance imaging can be used to image VTE, with some modalities better suited to particular parts of the body and clinical scenarios than others...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29017700/switching-temporary-hemodialysis-catheters-to-long-term-catheters-exchange-versus-de-novo-placement-any-difference-in-line-infection-%C3%A2
#8
Maen Aboul Hosn, Zeina Nasser, Elias Elias, Walid Medawar, Majida Daouk, Jamal Hoballah, Fady Haddad
BACKGROUND: Shifting from a short-term catheter to a long-term one is done either by removing the old catheter and placing a new long-term one via fresh new puncture site, or by replacing the old catheter with a long-term one over a guidewire. AIM: We aimed to describe our technique in changing a temporary line to a long-term catheter (LTC) over a guidewire and to determine the incidence of line-related infections following this procedure. MATERIALS AND METHODS: A retrospective pilot study was conducted between 2005 and 2010 at the American University of Beirut Hospital...
October 11, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29017005/early-planned-removal-of-umbilical-venous-catheters-to-prevent-infection-in-newborn-infants
#9
REVIEW
Adrienne Gordon, Mark Greenhalgh, William McGuire
BACKGROUND: Lengthy duration of use may be a risk factor for umbilical venous catheter-associated bloodstream infection in newborn infants. Early planned removal of umbilical venous catheters (UVCs) is recommended to reduce the incidence of infection and associated morbidity and mortality. OBJECTIVES: To compare the effectiveness of early planned removal of UVCs (up to two weeks after insertion) versus an expectant approach or a longer fixed duration in preventing bloodstream infection and other complications in newborn infants...
October 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29016235/telemedicine-support-groups-for-home-parenteral-nutrition-users
#10
Eve-Lynn Nelson, Donna Macan Yadrich, Noreen Thompson, Shawna Wright, Kathaleen Stone, Natasia Adams, Marilyn Werkowitch, Carol E Smith
Patients receiving home parenteral nutrition (HPN), a life-sustaining intravenous (IV) infusion that provides nourishment and hydration to patients with short gut or inflammatory bowel diseases, are often isolated and not in visual contact with peers or health providers. One completed clinical trial (Clinical Trials.gov NCT0190028) and 1 ongoing clinical trial (Clinical Trials.gov NCT02987569) are evaluating a mobile videoconferencing-delivered support group intervention for patients on HPN and their caregivers...
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28990241/clinically-indicated-replacement-versus-routine-replacement-of-peripheral-venous-catheters-in-adults-a-nonblinded-cluster-randomized-trial-in-china
#11
Lichun Xu, Yan Hu, Xiaojin Huang, Jianguo Fu, Jinhui Zhang
AIM: The purpose of this study was to investigate the safety of clinically indicated peripheral intravenous catheters (PIVC) replacement intervals. BACKGROUND: Peripheral intravenous catheters are used internationally, including in China where PIVCs are routinely replaced every 72 to 96 hours. Despite some recent international evidence showing such routine replacement is unnecessary, developing countries such as China have no supporting data. METHOD: This cluster-randomized trial was conducted between December 2 and December 31, 2013, in 10 internal medicine wards and 10 surgery wards at a tertiary referral teaching hospital in Xiamen, China...
October 9, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28989043/cerebrospinal-fluid-leak-at-percutaneous-exit-of-ventricular-catheter-as-crucial-risk-factor-for-external-ventricular-drainage-related-infection-in-adult-neurosurgical-patients
#12
Jaechan Park, Yeon-Ju Choi, Boram Ohk, Hyun-Ha Chang
OBJECTIVE: The placement of a ventricular catheter for temporary cerebrospinal fluid (CSF) diversion is associated with a considerable risk of CSF infection. The authors investigated the effect of a CSF leak on CSF-related infection and the predisposing factors for a CSF leak. METHODS: Fifty-two patients who underwent external ventricular drainage (EVD) for acute hydrocephalus associated with a subarachnoid hemorrhage (SAH) or intraventricular hemorrhage (IVH) were enrolled in this prospective study...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28977087/complications-of-central-venous-catheter-insertion-in-a-teaching-hospital
#13
Pedro Henrique Comerlato, Taiane Francieli Rebelatto, Felipe Augusto Santiago de Almeida, Luiza Birck Klein, Marcio Manozzo Boniatti, Beatriz D Schaan, Dimitris Varvaki Rados
INTRODUCTION: Central venous catheters are fundamental to daily clinical practice. This procedure is mainly performed by residents, often without supervision or structured training. OBJECTIVE: To describe the characteristics of central venous catheterization and the complication rate related to it. METHOD: Retrospective cohort study. Adult patients undergoing central venous catheter insertion out of the intensive care unit (ICU) of a teaching hospital were selected from March 2014 to February 2015...
July 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28971093/antimicrobial-peptides-in-biomedical-device-manufacturing
#14
REVIEW
Martijn Riool, Anna de Breij, Jan W Drijfhout, Peter H Nibbering, Sebastian A J Zaat
Over the past decades the use of medical devices, such as catheters, artificial heart valves, prosthetic joints, and other implants, has grown significantly. Despite continuous improvements in device design, surgical procedures, and wound care, biomaterial-associated infections (BAI) are still a major problem in modern medicine. Conventional antibiotic treatment often fails due to the low levels of antibiotic at the site of infection. The presence of biofilms on the biomaterial and/or the multidrug-resistant phenotype of the bacteria further impair the efficacy of antibiotic treatment...
2017: Frontiers in Chemistry
https://www.readbyqxmd.com/read/28968598/prognostic-factors-of-human-immunodeficiency-virus-infected-patients-on-chronic-hemodialysis
#15
Ivo Laranjinha, Patrícia João Matias, Jorge Dickson, Hermínia Estibeiro, Helena Boquinhas, José Diogo Barata
BACKGROUND/AIMS: The number of human immunodeficiency virus (HIV)-infected patients on hemodialysis (HD) have increased, and their prognostic factors are still poorly clarified. The study aimed to identify factors that can influence the survival of HIV-infected patients on HD. METHODS: We performed a retrospective cohort study of 44 HIV-infected patients on HD. RESULTS: A total of 17 patients (39%) died. Median survival on HD was 30.8 months and the survival rate at 1 and 5 years was 82...
October 3, 2017: Blood Purification
https://www.readbyqxmd.com/read/28967509/skin-antisepsis-with-0-05-sodium-hypochlorite-before-central-venous-catheter-insertion-in-neonates-a-2-year-single-center-experience
#16
Matilde Ciccia, Roksana Chakrokh, Dario Molinazzi, Angela Zanni, Patrizia Farruggia, Fabrizio Sandri
AIM: The study reports a 2-year single-center experience of the practice of skin antisepsis using a 0.05% sodium hypochlorite solution before central venous catheter placement in neonates. METHODS: Eligible subjects included any hospitalized neonate who needed a central line for at least 48 hours. Infants were excluded if they had a generalized or localized skin disorder. An ad hoc Excel (Microsoft Corp, Redmond, WA) file was used to record the data from each patient...
September 26, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28966069/biotimer-assay-a-reliable-and-rapid-method-for-the-evaluation-of-central-venous-catheter-microbial-colonization
#17
Luigi Rosa, Antimo Cutone, Monica Coletti, Maria Stefania Lepanto, Mellani Scotti, Piera Valenti, Giammarco Raponi, Maria Cristina Ghezzi, Francesca Berlutti
Adherent bacteria and biofilm frequently colonize central venous catheters (CVCs). CVC colonization is correlated to infections and particularly to bloodstream ones. The classical microbiological methods to determine of CVC colonization are not fully reliable and are time-consuming. BioTimer Assay (BTA) is a biological method already used to count bacteria adherent to abiotic surfaces and biofilm without sample manipulation. BTA employs specific reagents whose color changed according to bacterial metabolism...
September 29, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28951848/successful-treatment-of-aureobasidium-pullulans-central-catheter-related-fungemia-and-septic-pulmonary-emboli
#18
Sanjay R Mehta, Scott Johns, Paul Stark, Joshua Fierer
INTRODUCTION: Aureobasidium pullulans is a saprophytic fungus that is widely distributed in the environment, and in the right host can be an opportunistic human pathogen. PRESENTATION OF CASE: A 66-year-old man with Crohn's disease with a single kidney, and requiring total parenteral nutrition via a Hickman catheter, was admitted with a 10-week history of progressive shortness of breath, fevers and weight loss. Chest imaging demonstrated new multifocal lung parenchymal opacities compatible with septic pulmonary emboli...
2017: IDCases
https://www.readbyqxmd.com/read/28951333/complications-during-the-treatment-of-diabetic-foot-osteomyelitis
#19
Suzanne A V van Asten, Moez Mithani, Edgar J G Peters, Javier La Fontaine, Paul J Kim, Lawrence A Lavery
AIM: To identify complications of medical treatment in patients with diabetic foot osteomyelitis (DFO). METHODS: We reviewed 143 records of consecutive patients admitted with DFO, confirmed by bone histopathology or culture. Complications monitored included acute kidney injuries (AKI), development of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), gastrointestinal complications, and venous catheter related complications during a 12 months follow-up period...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28936879/parenteral-therapy-and-complications-in-patients-with-intestinal-failure-in-a-regional-unit
#20
Ruben Lorentsen, Lars Kristian Munck, Signe Wildt
OBJECTIVE: To describe a cohort of patients with intestinal failure (IF) and tunnelled catheters in a regional IF unit, treatment and catheter-related complication rates, and to compare the quality of care with previously published results from specialised IF centres in Denmark. METHODS: A retrospective chart review of an adult IF patient cohort receiving parenteral therapy through tunnelled catheters in a regional IF unit from 2005 to 2014. Demographics, indication, type and frequency of parenteral therapy, dwell time, cause of removal and complications were recorded...
September 22, 2017: Scandinavian Journal of Gastroenterology
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