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https://www.readbyqxmd.com/read/28213231/stable-isotope-labeling-assisted-liquid-chromatography-tandem-mass-spectrometry-for-the-analysis-of-perfluorinated-carboxylic-acids-in-serum-samples
#1
Shijuan Zhang, Zhongyin Ji, Zhiwei Sun, Mingshuang Li, Cuncun Sheng, Mingbo Yue, Yanxin Yu, Guang Chen, Jinmao You
A new stable isotope labeling (SIL) reagent pair, 10-methyl-acridone-2-sulfonohydrazide (MASH) and its deuterated counterpart d3-MASH was synthesized and successfully applied to the analysis of perfluorinated carboxylic acids (PFCAs) in serum samples. The limits of detection (LODs) were in the range of 0.07-0.42μg/L, and the limits of quantitation (LOQs) were in the range of 0.25-1.38μg/L. Besides ionization enhancing effect, MASH also showed excellent fluorescence property. Therefore, the mass spectrometer operation cost was greatly lowered by carrying out parameter optimization experiments on HPLC which is easier to operate and maintain...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213057/utilization-of-sentinel-lymph-node-biopsy-for-uterine-cancer
#2
Jason D Wright, Stephanie Cham, Ling Chen, William M Burke, June Y Hou, Ana I Tergas, Vrunda Desai, Jim C Hu, Cande V Ananth, Alfred I Neugut, Dawn L Hershman
BACKGROUND: To limit the potential short and long-term morbidity of lymphadenectomy, sentinel lymph node (SLN) biopsy has been proposed for endometrial cancer. The principle of SLN biopsy relies on removal of a small number of lymph nodes that are the first drainage basins from a tumor and thus the most likely to harbor tumor cells. While the procedure may reduce morbidity, efficacy data is limited and little is known about how commonly the procedure is performed. OBJECTIVE: We examined the patterns and predictors of use of SLN biopsy and outcomes of the procedure in women with endometrial cancer who underwent hysterectomy...
February 14, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28212911/the-effect-of-instructional-supervision-by-an-operating-room-assistant-on-first-case-starts
#3
Xiaohua Pan, Jun Zhang, Chen Dai, Yibing Si
BACKGROUND: Delays in starting first cases of the day are a common topic associated with high economic costs. PURPOSE: This study aimed to determine if an operating room (OR) assistant using an instructional supervision program could reduce the tardiness of first-case starts. DESIGN: A prospective study was conducted. Data from four ORs were used to compare the effectiveness of an instructional intervention to reduce delays in starting first cases of the day...
February 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28212647/an-interpretive-review-of-consensus-statements-on-clinical-guideline-development-and-their-application-in-the-field-of-traditional-and-complementary-medicine
#4
Jennifer Hunter, Matthew Leach, Lesley Braun, Alan Bensoussan
BACKGROUND: Despite ongoing consumer demand and an emerging scientific evidence-base for traditional and complementary medicine (T&CM), there remains a paucity of reliable information in standard clinical guidelines about their use. Often T&CM interventions are not mentioned, or the recommendations arising from these guidelines are unhelpful to end-users (i.e. patients, practitioners and policy makers). Insufficient evidence of efficacy may be a contributing factor; however, often informative recommendations could still be made by drawing on relevant information from other avenues...
February 17, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28212177/neurocognitive-outcomes-for-acute-global-acquired-brain-injury-in-children
#5
Fenella J Kirkham
PURPOSE OF REVIEW: In children, acute global brain injury from traumatic brain injury (TBI) and nontraumatic coma has a substantial cost to the child, the family, and the society. There have historically been relatively few studies looking at long-term cognition and behavioural outcomes. RECENT FINDINGS: Long-term follow-up studies, population-based studies, and meta-analyses are now available for TBI in children as well as adults and suggest that there is a significant cognitive cost, particularly for processing speed, working memory, and intelligence quotient (IQ) in severe TBI...
February 15, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28211634/prediction-of-forearm-bone-shape-based-on-partial-least-squares-regression-from-partial-shape
#6
Keiichiro Oura, Yoshito Otake, Atsuo Shigi, Futoshi Yokota, Tsuyoshi Murase, Yoshinobu Sato
BACKGROUND: Computer-assisted corrective osteotomy using a mirror image of the normal contralateral shape as reference is increasingly used. Instead, we propose to use the shape predicted by statistical learning to deal with cases demonstrating bilateral abnormality, such as bilateral trauma, congenital disease, and metabolic disease. METHODS: Computed tomography (CT) scans of 100 normal forearms were used in this study. The whole bone shape was predicted from its partial shape based on statistical learning of the other 99 bones...
February 17, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28211251/burden-of-rheumatoid-arthritis-from-a-societal-perspective-a-prevalence-based-study-on-cost-of-illness-for-patients-with-rheumatoid-arthritis-in-china
#7
Hao Hu, Luan Luan, Keqin Yang, Shu-Chuen Li
AIM: To provide a comprehensive estimation of the economic burden of rheumatoid arthritis (RA) in China, especially for patients from less developed areas, and to explore the cost transferability between regions to assist healthcare decision-making. METHODS: The study was conducted in south and north China from May 2013 to December 2013. The burden of RA was investigated by interviewing participants with a questionnaire battery containing socio-demographic, cost of illness (COI) and medical treatments...
February 17, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28210617/inpatient-treatment-for-the-middle-aged-and-elderly-in-central-china
#8
Yan Jiang, Yu Wang, Yang Li, Yuming Zhang, Yinjun Zhao, Xiaojun Wang, Chi Ma, Shuangge Ma
BACKGROUND: Compared to outpatient treatment and self-treatment, inpatient treatment corresponds to more severe illness and poses more serious health and financial burden to patients. The goal of this study is to provide an updated and comprehensive description of the prevalence, characteristics, and cost of inpatient treatment for the middle-aged and elderly in Central China, which is highly populated, less-developed, and agriculture-dominating. METHODS: A survey was conducted in August 2013 in the Henan province...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28210321/telemedicine-in-chronic-obstructive-pulmonary-disease
#9
Nicolino Ambrosino, Guido Vagheggini, Stefano Mazzoleni, Michele Vitacca
: Telemedicine is a medical application of advanced technology to disease management. This modality may provide benefits also to patients with chronic obstructive pulmonary disease (COPD). Different devices and systems are used. The legal problems associated with telemedicine are still controversial. Economic advantages for healthcare systems, though potentially high, are still poorly investigated. A European Respiratory Society Task Force has defined indications, follow-up, equipment, facilities, legal and economic issues of tele-monitoring of COPD patients including those undergoing home mechanical ventilation...
December 2016: Breathe
https://www.readbyqxmd.com/read/28210100/the-cost-effectiveness-of-a-nsclc-patient-assistance-program-for-pemetrexed-maintenance-therapy-in-people-s-republic-of-china
#10
Qiang Shi, Shanlian Hu, Wesley E Furnback, Gregory F Guzauskas, Jiejing Shen, Bruce Cm Wang
BACKGROUND: Eli Lilly and the China Primary Health Care Foundation are currently implementing a patient assistance program (PAP) in China, which allows first-line nonsquamous non-small-cell lung cancer (NSCLC) patients who complete four cycles of pemetrexed induction therapy to receive free, continuous pemetrexed maintenance therapy. OBJECTIVE: To estimate the cost-effectiveness of pemetrexed maintenance therapy vs basic standard care (BSC) and the economic impacts of providing a PAP for pemetrexed maintenance therapy to NSCLC patients who have completed pemetrexed induction therapy in a Chinese health care setting...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28207724/psychosocial-enhancement-of-the-green-prescription-for-obesity-recovery-a-randomised-controlled-trial
#11
Doug Sellman, Ria Schroder, Daryle Deering, Jane Elmslie, James Foulds, Chris Frampton
AIMS: Kia Ākina is a low-cost obesity recovery network providing ongoing addiction-orientated psychosocial support. This study explored the impact of Kia Ākina when added to the Green Prescription, a key government-funded health promotion programme in New Zealand. METHODS: A randomised controlled trial (ACTRN12613001160729) involving 108 participants recruited from primary care compared Green Prescription plus Kia Ākina (KA/GRx) with Green Prescription alone (GRx) over 12 months...
February 17, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28207400/a-low-cost-adaptive-balance-training-platform-for-stroke-patients-a-usability-study
#12
Sunny Verma, Deepesh Kumar, Animesh Kumawat, Anirban Dutta, Uttama Lahiri
Stroke patients usually suffer from asymmetric posture due to hemi-paresis that can result in reduced postural controllability leading to a balance deficit. This deficit increases the risk of falls, which often makes them dependent on caregivers for community ambulation, thus deteriorating their quality of life. Conventional balance training involves rehabilitation exercises performed under physiotherapist's supervision where the scarcity of trained professionals as well as the cost of clinic-based rehabilitation programs can deter stroke survivors from undergoing regular balance training...
February 9, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28205149/making-implicit-assumptions-explicit-in-the-costing-of-informal-care-the-case-of-head-and-neck-cancer-in-ireland
#13
Paul Hanly, Rebecca Maguire, Myles Balfe, Eleanor O'Sullivan, Linda Sharp
BACKGROUND: From a health service perspective, informal care is often viewed as a potentially cost-effective way of transferring costs out of the formal healthcare sector. However, informal care is not a free resource. OBJECTIVE: Our objective was to assess the impact of alternative valuation methods and key assumptions on the cost of informal care. METHODS: Informal carers who assisted in the care of a head and neck cancer survivor for at least 1 year were sent a postal questionnaire during January-June 2014 requesting information on time spent on caring tasks in the month prior to the survey...
February 15, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28205108/water-assisted-colonoscopy
#14
REVIEW
Sergio Cadoni, Felix W Leung
The current review will attempt to describe the important lessons learned from published randomized controlled trials (RCT) comparing water immersion (WI) or water exchange (WE) techniques with gas insufflation colonoscopy. Air insufflation (AI) to distend the colon to permit visualization and passage through the lumen was developed for diagnostic colonoscopy. When screening colonoscopy was adopted, the same AI method was used. Interval cancers, diagnosed within 3 to 5 years after an index screening colonoscopy, appeared to be linked to low adenoma detection rate (ADR)...
February 15, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28203556/complete-mesocolic-excision-in-right-hemicolectomy-comparison-between-hand-assisted-laparoscopic-and-open-approaches
#15
Qin-Song Sheng, Zhe Pan, Jin Chai, Xiao-Bin Cheng, Fan-Long Liu, Jin-Hai Wang, Wen-Bin Chen, Jian-Jiang Lin
PURPOSE: To demonstrate the feasibility, safety, and technical strategies of hand-assisted laparoscopic complete mesocolic excision (HAL-CME) and to compare oncological outcomes between HAL-CME and the open approach (O-CME) for right colon cancers. METHODS: Patients who were scheduled to undergo a right hemicolectomy were divided into HAL-CME and O-CME groups. Measured outcomes included demographic variables, perioperative parameters, and follow-up data. Demographic variables included age, sex distribution, body mass index (BMI), American Society of Anesthesiologists (ASA) physical status classification, previous abdominal surgery, tumor localization, and potential comorbidities...
February 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28202796/evaluation-of-genotypic-and-phenotypic-protease-virulence-tests-for-dichelobacter-nodosus-infection-in-sheep
#16
Andrew S McPherson, Om P Dhungyel, Richard J Whittington
Dichelobacter nodosus is a fastidious, strictly anaerobic bacterium, an obligate parasite of the ruminant hoof and the essential causative agent of virulent ovine footrot. The clinical disease results from a complex interplay between pathogen, environment and host. Sheep flocks diagnosed with virulent but not benign footrot in Australia may be quarantined and required to undergo a compulsory eradication program, with costs met by the farmer. Virulence of D. nodosus is at least partially dependent on elaboration of a protease coded by aprV2 and manifest as elastase activity...
February 15, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28202100/low-income-adults-perceptions-of-farmers-markets-and-community-supported-agriculture-programmes
#17
Elizabeth W Cotter, Carla Teixeira, Annessa Bontrager, Kasharena Horton, Deyanira Soriano
OBJECTIVE: To better understand low-income adults' attitudes towards participating in farmers' markets, community-supported agriculture (CSA) and nutrition education programming. DESIGN: Focus groups were held with a diverse sample of adults. Interviews were transcribed verbatim and analysed using thematic analysis. SETTING: Three affordable housing communities in Washington, DC, USA. SUBJECTS: Participants included twenty-eight residents of the three affordable housing communities...
February 16, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28199267/organizational-and-community-factors-associated-with-magnet-status-of-u-s-hospitals
#18
Teresa Wai Chi Tai, Sherry I Bame
The Magnet Recognition Program for healthcare organizations promotes excellence in nursing services and professional practices. However, organizational and community characteristics that contribute to the adoption of Magnet status remain unexplained. Investigating organizational and community factors will help determine systematic structural and contextual dimensions of Magnet hospitals previously shown to be more cost-effective in comparison with non-Magnet hospitals. Using the baseline 2005 database of all Magnet hospitals in the United States, the authors selected a matched sample to determine key organizational and community characteristics associated with Magnet adoption while controlling for regional and local factors...
January 2017: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28198565/training-nonnursing-staff-to-assist-with-nutritional-care-delivery-in-nursing-homes-a-cost-effectiveness-analysis
#19
Sandra F Simmons, Emily K Hollingsworth, Emily A Long, Xulei Liu, Matthew S Shotwell, Emmett Keeler, Ruopeng An, Heidi J Silver
OBJECTIVES: To determine the effect and cost-effectiveness of training nonnursing staff to provide feeding assistance for nutritionally at-risk nursing home (NH) residents. DESIGN: Randomized, controlled trial. SETTING: Five community NHs. PARTICIPANTS: Long-stay NH residents with an order for caloric supplementation (N = 122). INTERVENTION: Research staff provided an 8-hour training curriculum to nonnursing staff...
February 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28197153/genetic-dissection-of-novel-qtls-for-resistance-to-leaf-spots-and-tomato-spotted-wilt-virus-in-peanut-arachis-hypogaea-l
#20
Manish K Pandey, Hui Wang, Pawan Khera, Manish K Vishwakarma, Sandip M Kale, Albert K Culbreath, C Corley Holbrook, Xingjun Wang, Rajeev K Varshney, Baozhu Guo
Peanut is an important crop, economically and nutritiously, but high production cost is a serious challenge to peanut farmers as exemplified by chemical spray to control foliar diseases such as leaf spots and thrips, the vectors of tomato spotted wilt virus (TSWV). The objective of this research was to map the quantitative trait loci (QTLs) for resistance to leaf spots and TSWV in one recombinant inbred line (RIL) mapping population of "Tifrunner × GT-C20" for identification of linked markers for marker-assisted breeding...
2017: Frontiers in Plant Science
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