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https://www.readbyqxmd.com/read/29165952/identifying-and-eliminating-the-barriers-to-patient-education-for-patients-in-the-early-stages-of-chronic-kidney-disease
#1
Sherry Rivera
Patients with chronic kidney disease (CKD) often do not have the knowledge they need to adequately manage their disease and prevent progression. Educating patients with the early stages of CKD is warranted and may assist in delaying progression of disease, improving outcomes, and reducing health expenditures. However, evidence is currently lacking regarding the best methods and approach to educating patients in the early stages of CKD. Multiple patient, provider, and system barriers can interfere with the delivery of patient education in the early stages of CKD...
May 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29165558/-she-had-a-smile-on-her-face-as-wide-as-the-great-australian-bite-a-qualitative-examination-of-family-perceptions-of-a-therapeutic-robot-and-a-plush-toy
#2
Wendy Moyle, Marguerite Bramble, Cindy J Jones, Jenny E Murfield, Barbara J Bowers
Background and Objectives: Recent years have seen social robotic pets introduced as a means of treating behavioral and psychological symptoms of dementia, and many show promising potential. In this study, we sought to explore family members' perceptions of the Japanese-developed baby harp seal, Paro (version 9), and a look-alike, nonrobotic Plush Toy, when used by their relative with dementia for 15 min, 3 afternoons per week for 10 weeks. Research Design and Method: The study employed a descriptive qualitative approach, which was nested within a larger cluster randomized controlled trial...
November 19, 2017: Gerontologist
https://www.readbyqxmd.com/read/29162950/intrauterine-insemination-fundamentals-revisited
#3
EDITORIAL
Gautam N Allahbadia
Intrauterine insemination (IUI) is an assisted conception technique that involves the deposition of a processed semen sample in the upper uterine cavity, overcoming natural barriers to sperm ascent in the female reproductive tract. It is a cost-effective, noninvasive first-line therapy for selected patients with functionally normal tubes, and infertility due to a cervical factor, anovulation, moderate male factor, unexplained factors, immunological factor, and ejaculatory disorders with clinical pregnancy rates per cycle ranging from 10 to 20%...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162824/watt-level-10-gigahertz-solid-state-laser-enabled-by-self-defocusing-nonlinearities-in-an-aperiodically-poled-crystal
#4
A S Mayer, C R Phillips, U Keller
Femtosecond modelocked lasers with multi-gigahertz pulse repetition rates are attractive sources for all applications that require individually resolvable frequency comb lines or high sampling rates. However, the modelocked laser architectures demonstrated so far have several issues, including the need for single-mode pump lasers, limited output power, Q-switching instabilities and challenging cavity geometries. Here, we introduce a technique that solves these issues. In a two-dimensionally patterned quasi-phase-matching (QPM) device, we create a large, low-loss self-defocusing nonlinearity, which simultaneously provides SESAM-assisted soliton modelocking in the normal dispersion regime and suppresses Q-switching induced damage...
November 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/29162798/persistence-and-reversal-of-plasmid-mediated-antibiotic-resistance
#5
Allison J Lopatkin, Hannah R Meredith, Jaydeep K Srimani, Connor Pfeiffer, Rick Durrett, Lingchong You
In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace their resistant counterparts if resistance genes are costly. However, many resistance genes persist for long periods in the absence of antibiotics. Horizontal gene transfer (primarily conjugation) could explain this persistence, but it has been suggested that very high conjugation rates would be required. Here, we show that common conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics in Escherichia coli...
November 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/29162150/a-content-analysis-of-dissemination-and-implementation-science-resource-initiatives-what-types-of-resources-do-they-offer-to-advance-the-field
#6
Doyanne Darnell, Caitlin N Dorsey, Abigail Melvin, Jonathan Chi, Aaron R Lyon, Cara C Lewis
BACKGROUND: The recent growth in organized efforts to advance dissemination and implementation (D & I) science suggests a rapidly expanding community focused on the adoption and sustainment of evidence-based practices (EBPs). Although promising for the D & I of EBPs, the proliferation of initiatives is difficult for any one individual to navigate and summarize. Such proliferation may also result in redundant efforts or missed opportunities for participation and advancement. A review of existing D & I science resource initiatives and their unique merits would be a significant step for the field...
November 21, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29162145/reducing-hospital-admissions-in-remote-australia-through-the-establishment-of-a-palliative-and-chronic-disease-respite-facility
#7
Timothy A Carey, Mick Arundell, Kellie Schouten, John S Humphreys, Fred Miegel, Simon Murphy, John Wakerman
BACKGROUND: There are limited respite services for palliative care patients and their families in the Northern Territory (NT). The high prevalence of complex chronic diseases, limited access to primary care services, and the poor living situations of many Aboriginal and Torres Strait Islander Australians result in high hospitalisation rates and pressure on tertiary health services. Palliative Care NT identified a need for a flexible, community based, culturally appropriate respite service in Alice Springs...
November 21, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/29162107/production-of-highly-efficient-cellulase-mixtures-by-genetically-exploiting-the-potentials-of-trichoderma-reesei-endogenous-cellulases-for-hydrolysis-of-corncob-residues
#8
Yuanchao Qian, Lixia Zhong, Jia Gao, Ningning Sun, Yifan Wang, Guoyong Sun, Yinbo Qu, Yaohua Zhong
BACKGROUND: Trichoderma reesei is one of the most important fungi utilized for cellulase production. However, its cellulase system has been proven to be present in suboptimal ratio for deconstruction of lignocellulosic substrates. Although previous enzymatic optimization studies have acquired different types of in vitro synthetic mixtures for efficient lignocellulose hydrolysis, production of in vivo optimized cellulase mixtures by industrial strains remains one of the obstacles to reduce enzyme cost in the biofuels production from lignocellulosic biomass...
November 21, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/29160426/impact-assessment-of-an-automated-drug-dispensing-system-in-a-tertiary-hospital
#9
Débora de-Carvalho, José Luiz Alvim-Borges, Cristiana Maria Toscano
OBJECTIVE: To evaluate the costs and patient safety of a pilot implementation of an automated dispensing cabinet in a critical care unit of a private tertiary hospital in São Paulo/Brazil. METHODS: This study considered pre- (January-August 2013) and post- (October 2013-October 2014) intervention periods. We considered the time and cost of personnel, number of adverse events, audit adjustments to patient bills, and urgent requests and returns of medications to the central pharmacy...
October 2017: Clinics
https://www.readbyqxmd.com/read/29159426/an-initial-cost-effectiveness-analysis-of-intraoperative-magnetic-resonance-imaging-imri-in-pediatric-epilepsy-surgery
#10
Matthew F Sacino, Sean S Huang, Robert F Keating, William D Gaillard, Chima O Oluigbo
PURPOSE: Previous studies have illustrated the clinical utility of the addition of intraoperative magnetic resonance imaging (iMRI) to conventional microsurgical resection. While iMRI requires initial capital cost investment, long-term reduction in costly follow-up management and reoperation costs may prove economically efficacious. The objective of this study is to investigate the cost-effectiveness of the addition of iMRI utilization versus conventional microsurgical techniques in focal cortical dysplasia (FCD) resection in pediatric patients with medically refractory epilepsy...
November 20, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29158566/graphene-quantum-dots-for-cell-proliferation-nucleus-imaging-and-photoluminescent-sensing-applications
#11
Mukesh Kumar Kumawat, Mukeshchand Thakur, Raju B Gurung, Rohit Srivastava
We report a simple one-pot microwave assisted "green synthesis" of Graphene Quantum Dots (GQDs) using grape seed extract as a green therapeutic carbon source. These GQDs readily self-assemble, hereafter referred to as "self-assembled" GQDs (sGQDs) in the aqueous medium. The sGQDs enter via caveolae and clathrin-mediated endocytosis and target themselves into cell nucleus within 6-8 h without additional assistance of external capping/targeting agent. The tendency to self-localize themselves into cell nucleus also remains consistent in different cell lines such as L929, HT-1080, MIA PaCa-2, HeLa, and MG-63 cells, thereby serving as a nucleus labelling agent...
November 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29157376/epidemiological-and-partial-budget-analysis-for-treatment-of-subclinical-staphylococcus-aureus-intramammary-infections-considering-microbiological-and-cytological-scenarios
#12
Inge-Marié Petzer, Eric M C Etter, Edward F Donkin, Edward C Webb, Joanne Karzis
An innovative method was investigated to aid in the elimination of Staphylococcus aureus (S. aureus) intramammary infections (IMI) from dairy herds. A stochastic model explore the economic benefit of three-day or eight-day treatment of subclinical IMI in all S. aureus infected cows or in only those with a somatic cell count (SCC) exceeding 200,000 cells/ml. An epidemiological model was developed to run parallel to the economic model that would predict the S. aureus IMI likely to persist, develop new infections and clinical mastitis...
December 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29156558/indoor-temperatures-in-low-cost-housing-in-johannesburg-south-africa
#13
Nisha Naicker, June Teare, Yusentha Balakrishna, Caradee Yael Wright, Angela Mathee
Ambient and indoor temperature affects thermal comfort and human health. In a changing climate with a predicted change in temperature extremes, understanding indoor temperatures, both hot and cold, of different housing types is important. This study aimed to assess the hourly, daily and monthly variation in indoor temperatures in different housing types, namely formal houses, informal houses, flats, government-built low-cost houses and old, apartheid era low-cost housing, in five impoverished urban communities in Johannesburg, South Africa...
November 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29155782/partial-optic-nerve-transection-in-rats-a-model-established-with-a-new-operative-approach-to-assess-secondary-degeneration-of-retinal-ganglion-cells
#14
Fancheng Yan, Sailiang Guo, Yijie Chai, Lan Zhang, Kegao Liu, Qingjun Lu, Ningli Wang, Shuning Li
Previous studies have shown that the secondary degeneration of retinal ganglion cells (RGCs) occurs commonly in glaucoma. Partial optic nerve transection is considered a useful and reproducible model. Compared with other optic nerve injury models used commonly for assessing secondary degeneration, e.g. complete optic nerve transection and optic nerve crush models, the partial optic nerve transection model is superior as it distinguishes primary from secondary degeneration in situ. Therefore, it serves as an excellent tool for evaluating secondary degeneration...
October 15, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155771/endotracheal-intubation-of-rabbits-using-a-polypropylene-guide-catheter
#15
Krista L Thompson, Thomas R Meier, Jodi A Scholz
Endotracheal intubation in rabbits can be challenging due to their unusual anatomy. Achieving a patent airway during anesthesia is critical for the avoidance of airway obstruction, prevention of gastric tympany, and to allow ventilatory support. Due to the difficulty of intubation, alternative methods such as the use of laryngeal mask airways or laryngeal tubes have been explored. However, these methods do not result in direct access to the trachea and thus may present a risk for development of complications...
November 13, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155666/cdc-activities-for-improving-implementation-of-human-papillomavirus-vaccination-cervical-cancer-screening-and-surveillance-worldwide
#16
Virginia Senkomago, Denise Duran, Anagha Loharikar, Terri B Hyde, Lauri E Markowitz, Elizabeth R Unger, Mona Saraiya
Cervical cancer incidence and mortality rates are high, particularly in developing countries. Most cervical cancers can be prevented by human papillomavirus (HPV) vaccination, screening, and timely treatment. The US Centers for Disease Control and Prevention (CDC) provides global technical assistance for implementation and evaluation of HPV vaccination pilot projects and programs and laboratory-related HPV activities to assess HPV vaccines. CDC collaborates with global partners to develop global cervical cancer screening recommendations and manuals, implement screening, create standardized evaluation tools, and provide expertise to monitor outcomes...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29152968/natural-carbonized-sugar-as-a-low-temperature-ammonia-sensor-material-experimental-theoretical-and-computational-studies
#17
Balaji Ghule, Shoyebmohamad F Shaikh, Satish Ekar, Umesh Tukaram Nakate, Krishna Chaitanya Gunturu, Nanasaheb Shinde, Mu Naushad, Kwang Ho Kim, Colm O'Dwyer, Rajaram Mane
Bearing in mind the advantages of useful, cost-effective and eco-friendly synthesis, carbonized sugar (CS) has been synthesized via microwave-assisted carbonization of market quality table-top sugar. The as-prepared CS has been characterized for its morphology, phase purity, type of porosity and pore-size distribution. The gas sensing properties of CS for various oxidizing and reducing gases are demonstrated at ambient temperature where we observe good selectivity towards liquid ammonia amongst other gases...
November 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29151042/patient-centered-assessment-on-disease-burden-quality-of-life-and-treatment-satisfaction-associated-with-acromegaly
#18
Shuqian Liu, Daphne T Adelman, Yaping Xu, Jillone Sisco, Susan M Begelman, Susan M Webb, Xavier Badia, Tina K Thethi, Vivian Fonseca, Lizheng Shi
The study aimed to assess the economic burden, health-related quality of life (HRQoL), and acromegaly treatment satisfaction in the USA. A web-based, cross-sectional survey was distributed to members of Acromegaly Community. Data related to comorbidities, treatment patterns, and treatment satisfaction were collected. The costs over the past 3 months included out-of-pocket cost, sick leave, leave of absence, direct loss of job due to acromegaly, unemployment, assistance to perform household chores, and family member loss of income...
November 18, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/29149993/label-free-determination-of-prostate-specific-membrane-antigen-in-human-whole-blood-at-nanomolar-levels-by-magnetically-assisted-surface-enhanced-raman-spectroscopy
#19
Zuzana Chaloupková, Anna Balzerová, Jitka Bařinková, Zdenka Medříková, Pavel Šácha, Petr Beneš, Václav Ranc, Jan Konvalinka, Radek Zbořil
Prostate cancer is one of the most common cancers among men and can in its later stages cause serious medical problems. Due to the limited suitability of current diagnostic biochemical markers, new biomarkers for the detection of prostate cancer are highly sought after. An ideal biomarker should serve as a reliable prognostic marker, be applicable for early diagnosis, and be applicable for monitoring of therapeutic response. One potential candidate is glutamate carboxypeptidase II (GCPII), also known as prostate specific membrane antigen (PSMA), which has a promising role for direct imaging...
January 2, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29149991/a-fast-and-low-cost-microfabrication-approach-for-six-types-of-thermoplastic-substrates-with-reduced-feature-size-and-minimized-bulges-using-sacrificial-layer-assisted-laser-engraving
#20
Longjun Gu, Guodong Yu, Cheuk-Wing Li
Since polydimethylsiloxane (PDMS) is notorious for its severe sorption to biological compounds and even nanoparticles, thermoplastics become a promising substrate for microdevices. Although CO2 laser engraving is an efficient method for thermoplastic device fabrication, it accompanies with poor bonding issues due to severe bulging and large feature size determined by the diameter of laser beam. In this study, a low-cost microfabrication method is proposed by reversibly sealing a 1 mm thick polymethylmethacrylate (PMMA) over an engraving substrate to reduce channel feature size and minimize bulges of laser engraved channels...
January 2, 2018: Analytica Chimica Acta
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