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Auditory hallucinations

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https://www.readbyqxmd.com/read/29755393/language-lateralization-and-auditory-attention-impairment-in-young-adults-at-ultra-high-risk-for-psychosis-a-dichotic-listening-study
#1
Ingvild Aase, Kristiina Kompus, Jens Gisselgård, Inge Joa, Jan O Johannessen, Kolbjørn Brønnick
Objectives: Impaired attention and language functions are common in psychosis, but have been less explored in subjects with ultra-high risk for psychosis (UHR). The aim of the study was to investigate differences in language lateralization and auditory attention in UHR subjects compared to healthy controls with a dichotic listening paradigm. In addition, symptoms from The Structural Interview for Prodromal Syndromes (SIPS) were explored in relation to performance on dichotic listening. Methods: The UHR subjects ( n = 46, female = 28, mean age = 17...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29742332/clinical-features-of-auditory-hallucinations-in-patients-with-dementia-with-lewy-bodies-a-soundtrack-of-visual-hallucinations
#2
Naoko Tsunoda, Mamoru Hashimoto, Tomohisa Ishikawa, Ryuji Fukuhara, Seiji Yuki, Hibiki Tanaka, Yutaka Hatada, Yusuke Miyagawa, Manabu Ikeda
OBJECTIVE: Auditory hallucinations are an important symptom for diagnosing dementia with Lewy bodies (DLB), yet they have received less attention than visual hallucinations. We investigated the clinical features of auditory hallucinations and the possible mechanisms by which they arise in patients with DLB. METHODS: We recruited 124 consecutive patients with probable DLB (diagnosis based on the DLB International Workshop 2005 criteria; study period: June 2007-January 2015) from the dementia referral center of Kumamoto University Hospital...
May 8, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29733409/neural-correlates-of-auditory-verbal-hallucinations-in-schizophrenia-and-the-therapeutic-response-to-theta-burst-transcranial-magnetic-stimulation
#3
Xingui Chen, Gong-Jun Ji, Chunyan Zhu, Xiaomeng Bai, Lu Wang, Kongliang He, Yaxiang Gao, Longxiang Tao, Fengqiong Yu, Yanghua Tian, Kai Wang
Auditory verbal hallucinations (AVHs) are a core symptom of schizophrenia, and resistant to antipsychotic medication in a substantial proportion of patients. This study aimed to investigate the neural correlates of AVHs in schizophrenia patients and its response to a modified continuous theta-burst stimulation (cTBS) by transcranial magnetic stimulation. In a cross-sectional experiment, resting-state functional magnetic resonance images were collected from 31 AVH schizophrenia patients, 26 non-AVH schizophrenia patients, and 33 sex-/age-matched healthy controls (HCs)...
May 3, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29719360/neuropsychiatric-symptoms-induced-by-large-doses-of-nitrous-oxide-inhalation-a-case-report
#4
Tianzhen Chen, Na Zhong, Haifeng Jiang, Min Zhao, Zhikang Chen, Haiming Sun
Nitrous Oxide, which is also called laughing gas, now ranks as the 7th most popular drug in the world. Nitrous oxide mainly disturbs B12 metabolism and damages nerves, followed by apparent neuropsychiatric symptoms. It's beneficial to the prognosis of patients if we identify and treat their symptoms early. This case report describes a 19-year-old male who presented with auditory hallucination, persecutory delusions and unstable emotions after abuse of nitrous oxide over the course of half a year. Moreover, neurological signs such as weakness and hyperesthesia also appeared...
February 25, 2018: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29713292/avatar-therapy-for-persistent-auditory-verbal-hallucinations-in-an-ultra-resistant-schizophrenia-patient-a-case-report
#5
Laura Dellazizzo, Stéphane Potvin, Kingsada Phraxayavong, Pierre Lalonde, Alexandre Dumais
Effective treatment strategies for schizophrenia remain very challenging and many treatment-resistant patients will suffer from persistent auditory verbal hallucinations (AVH). While clozapine is the gold-standard medication for this complex population, many will not respond to this molecule. For these ultra-resistant patients, limited options are available. Cognitive-behavioral therapy (CBT) is the most widely used psychological intervention, though it offers modest effects. With the interpersonal dimension of AVH being recognized, Avatar Therapy (AT), a novel experiential treatment enabling patients to create an avatar of their persecutor and allowing them to gain control over their symptoms, was developed and tested...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29703662/dysregulation-of-auditory-neuroplasticity-in-schizophrenia
#6
Patrice Voss, Maryse E Thomas, Gerson D Guercio, Etienne de Villers-Sidani
Schizophrenia is a complex brain syndrome characterized by an array of positive symptoms (delusions, hallucinations, disorganized speech), negative symptoms (alogia, apathy, avolition) and cognitive impairments (memory, executive functions). Although investigations of the cognitive deficits in schizophrenia have primarily concentrated on disturbances affecting higher-order cognitive processes, there is an increasing realization that schizophrenia also affects early sensory processing, which might, in fact, play a significant role in the development of higher-order cognitive impairments...
April 24, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29684224/mismatch-negativity-and-cortical-thickness-in-patients-with-schizophrenia-and-bipolar-disorder
#7
Sungkean Kim, Hyeonjin Jeon, Kuk-In Jang, Yong-Wook Kim, Chang-Hwan Im, Seung-Hwan Lee
Introduction: Mismatch negativity (MMN) is a measure of automatic neurophysiological brain processes for detecting unexpected sensory stimuli. This study investigated MMN reduction in patients with schizophrenia and bipolar disorder and examined whether cortical thickness is associated with MMN, for exploratory purposes. Methods: Electroencephalograms were recorded in 38 patients with schizophrenia, 37 patients with bipolar disorder, and 32 healthy controls (HCs) performing a passive auditory oddball paradigm...
April 19, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29683518/the-function-and-failure-of-sensory-predictions
#8
REVIEW
Sonia Bansal, Judith M Ford, Miriam Spering
Humans and other primates are equipped with neural mechanisms that allow them to automatically make predictions about future events, facilitating processing of expected sensations and actions. Prediction-driven control and monitoring of perceptual and motor acts are vital to normal cognitive functioning. This review provides an overview of corollary discharge mechanisms involved in predictions across sensory modalities and discusses consequences of predictive coding for cognition and behavior. Converging evidence now links impairments in corollary discharge mechanisms to neuropsychiatric symptoms such as hallucinations and delusions...
April 23, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29682608/-hallucinations-following-acute-cannabis-dosing-a-case-report-and-comparison-to-other-hallucinogenic-drugs
#9
Frederick S Barrett, Nicolas J Schlienz, Natalie Lembeck, Muhammad Waqas, Ryan Vandrey
Introduction: Cannabis has been historically classified as a hallucinogen. However, subjective cannabis effects do not typically include hallucinogen-like effects. Empirical reports of hallucinogen-like effects produced by cannabis in controlled settings, particularly among healthy research volunteers, are rare and have mostly occurred after administration of purified Δ-9 tetrahydrocannabinol (THC) rather than whole plant cannabis. Methods: The case of a healthy 30-year-old male who experienced auditory and visual hallucinations in a controlled laboratory study after inhaling vaporized cannabis that contained 25 mg THC (case dose) is presented...
2018: Cannabis and Cannabinoid Research
https://www.readbyqxmd.com/read/29660570/the-tangled-roots-of-inner-speech-voices-and-delusions
#10
Cherise Rosen, Simon McCarthy-Jones, Kayla A Chase, Clara S Humpston, Jennifer K Melbourne, Leah Kling, Rajiv P Sharma
The role of inner speech in the experience of auditory verbal hallucinations (AVH) and delusions remains unclear. This exploratory study tested for differences in inner speech (assessed via self-report questionnaire) between 89 participants with psychosis and 37 non-clinical controls. We also tested for associations of inner speech with, i) state/trait AVH, ii) AVH-severity; iii) patients' relations with their voices, and; iv) delusion-severity. Persons with psychosis had greater levels of dialogic inner speech, other people in inner speech, and evaluative/motivational inner speech than non-clinical controls...
April 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29660081/data-driven-analysis-of-functional-connectivity-reveals-a-potential-auditory-verbal-hallucination-network
#11
Dustin Scheinost, Fuyuze Tokoglu, Michelle Hampson, Ralph Hoffman, R Todd Constable
Schizophrenia is a severe global health problem, with over half of such patients experiencing auditory verbal hallucinations (AVHs). A better understanding of the neural correlates differentiating patients experiencing AVHs from patients not experiencing AVHs and healthy controls may identify targets that lead to better treatment strategies for AVHs. Employing 2 data-driven, voxel-based measure of functional connectivity, we studied 46 patients with schizophrenia or schizoaffective disorder (28 experiencing AVHs and 18 not experiencing AVHs)...
April 5, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29623839/identifying-patterns-in-signs-and-symptoms-preceding-the-clinical-diagnosis-of-alzheimer-s-disease-retrospective-medical-record-review-study-and-a-nested-case-control-design
#12
Fidelia Bature, Dong Pang, Anthea Robinson, Norma Polson, Yannis Pappas, Barbara Guinn
OBJECTIVE: Evidence suggests that individuals with Alzheimer's disease (AD) are often diagnosed in the later stages of their disease with a poor prognosis. This study aimed to identify patterns in signs and symptoms preceding the clinical diagnosis of AD to suggest a predictive model for earlier diagnosis of the disease in the primary care. DESIGN: A retrospective medical record review; nested case control design. PARTICIPANTS: Participants included one hundred and nine patients from three general practice (GP) surgeries in Milton Keynes and Luton Clinical Commissioning groups (CCG) (37 cases with AD and 72 controls without AD)...
April 4, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29593589/comorbid-diagnosis-of-psychotic-disorders-in-borderline-personality-disorder-prevalence-and-influence-on-outcome
#13
C W Slotema, Jan D Blom, Marieke B A Niemantsverdriet, Mathijs Deen, Iris E C Sommer
Background: A diagnosis of psychotic disorder is traditionally considered incompatible with borderline personality disorder (BPD), even though patients sometimes fulfill the diagnostic criteria for both disorders. How often this happens is barely known, as is the influence of comorbid psychotic disorders on the outcome of BPD. Since studies on isolated auditory verbal hallucinations in patients with BPD indicate that these perceptual symptoms have severe consequences and are associated with suicidal behavior and hospitalization, patients with comorbid psychotic disorders are unlikely to fare better...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29581420/aberrant-salience-network-functional-connectivity-in-auditory-verbal-hallucinations-a-first-episode-psychosis-sample
#14
Pavan Kumar Mallikarjun, Paris Alexandros Lalousis, Thomas Frederick Dunne, Kareen Heinze, Renate Lep Reniers, Matthew R Broome, Baldeep Farmah, Femi Oyebode, Stephen J Wood, Rachel Upthegrove
Auditory verbal hallucinations (AVH) often lead to distress and functional disability, and are frequently associated with psychotic illness. Previously both state and trait magnetic resonance imaging (MRI) studies of AVH have identified activity in brain regions involving auditory processing, language, memory and areas of default mode network (DMN) and salience network (SN). Current evidence is clouded by research mainly in participants on long-term medication, with chronic illness and by choice of seed regions made 'a priori'...
March 27, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29580740/negative-voice-content-as-a-full-mediator-of-a-relation-between-childhood-adversity-and-distress-ensuing-from-hearing-voices
#15
Cherise Rosen, Simon McCarthy-Jones, Nev Jones, Kayla A Chase, Rajiv P Sharma
A key predictor of whether or not an individual who hears voices (auditory verbal hallucinations; AVH) meets criteria for a psychiatric diagnosis is the level of negative content of the voices (e.g., threats, criticism, abuse). Yet the factors that contribute to negative voice-content are still not well understood. This study aimed to test the hypotheses that levels of childhood adversity would predict levels of negative voice-content, and that negative voice-content would partially mediate a relation between childhood adversity and voice-related distress...
March 23, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29571753/disrupted-network-cross-talk-hippocampal-dysfunction-and-hallucinations-in-schizophrenia
#16
Stephanie M Hare, Alicia S Law, Judith M Ford, Daniel H Mathalon, Aral Ahmadi, Eswar Damaraju, Juan Bustillo, Aysenil Belger, Hyo Jong Lee, Bryon A Mueller, Kelvin O Lim, Gregory G Brown, Adrian Preda, Theo G M van Erp, Steven G Potkin, Vince D Calhoun, Jessica A Turner
Hallucinations characterize schizophrenia, with approximately 59% of patients reporting auditory hallucinations and 27% reporting visual hallucinations. Prior neuroimaging studies suggest that hallucinations are linked to disrupted communication across distributed (sensory, salience-monitoring and subcortical) networks. Yet, our understanding of the neurophysiological mechanisms that underlie auditory and visual hallucinations in schizophrenia remains limited. This study integrates two resting-state functional magnetic resonance imaging (fMRI) analysis methods - amplitudes of low-frequency fluctuations (ALFF) and functional network connectivity (FNC) - to explore the hypotheses that (1) abnormal FNC between salience and sensory (visual/auditory) networks underlies hallucinations in schizophrenia, and (2) disrupted hippocampal oscillations (as measured by hippocampal ALFF) beget changes in FNC linked to hallucinations...
March 20, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29569473/neurofeedback-based-enhancement-of-single-trial-auditory-evoked-potentials-treatment-of-auditory-verbal-hallucinations-in-schizophrenia
#17
Kathryn Rieger, Marie-Helene Rarra, Laura Diaz Hernandez, Daniela Hubl, Thomas Koenig
Auditory verbal hallucinations depend on a broad neurobiological network ranging from the auditory system to language as well as memory-related processes. As part of this, the auditory N100 event-related potential (ERP) component is attenuated in patients with schizophrenia, with stronger attenuation occurring during auditory verbal hallucinations. Changes in the N100 component assumingly reflect disturbed responsiveness of the auditory system toward external stimuli in schizophrenia. With this premise, we investigated the therapeutic utility of neurofeedback training to modulate the auditory-evoked N100 component in patients with schizophrenia and associated auditory verbal hallucinations...
March 1, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29559020/gene-polymorphisms-and-response-to-transcranial-direct-current-stimulation-for-auditory-verbal-hallucinations-in-schizophrenia
#18
Harleen Chhabra, Venkataram Shivakumar, Manjula Subbanna, Sunil V Kalmady, Anushree Bose, Sri Mahavir Agarwal, Vanteemar S Sreeraj, Damodharan Dinakaran, Janardhanan C Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramanian
OBJECTIVE: Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong association with neuroplasticity effect in schizophrenia. METHODS: Schizophrenia patients (n=32) with treatment resistant auditory hallucinations were administered with an add-on tDCS...
March 21, 2018: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/29554989/auditory-hallucinations-in-adults-with-hearing-impairment-a-large-prevalence-study
#19
M M J Linszen, G A van Zanten, R J Teunisse, R M Brouwer, P Scheltens, I E Sommer
BACKGROUND: Similar to visual hallucinations in visually impaired patients, auditory hallucinations are often suggested to occur in adults with hearing impairment. However, research on this association is limited. This observational, cross-sectional study tested whether auditory hallucinations are associated with hearing impairment, by assessing their prevalence in an adult population with various degrees of objectified hearing impairment. METHODS: Hallucination presence was determined in 1007 subjects aged 18-92, who were referred for audiometric testing to the Department of ENT-Audiology, University Medical Center Utrecht, the Netherlands...
March 20, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29533819/randomized-trial-of-transcranial-alternating-current-stimulation-for-treatment-of-auditory-hallucinations-in-schizophrenia
#20
Juliann M Mellin, Sankaraleengam Alagapan, Caroline Lustenberger, Courtney E Lugo, Morgan L Alexander, John H Gilmore, L Fredrik Jarskog, Flavio Fröhlich
BACKGROUND: Approximately 30% of patients with schizophrenia experience auditory hallucinations that are refractory to antipsychotic medications. Here, we evaluated the feasibility and efficacy of transcranial alternating current stimulation (tACS) that we hypothesized would improve auditory hallucination symptoms by enhancing synchronization between the frontal and temporo-parietal areas of the left hemisphere. METHOD: 22 participants were randomized to one of three arms and received twice daily, 20 min sessions of sham, 10 Hz 2 mA peak-to-peak tACS, or 2 mA tDCS over the course of 5 consecutive days...
March 10, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
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