keyword
MENU ▼
Read by QxMD icon Read
search

Biofilms

keyword
https://www.readbyqxmd.com/read/28437232/epidemiological-physiological-and-molecular-characteristics-of-a-brazilian-collection-of-carbapenem-resistant-acinetobacter-baumannii-and-pseudomonas-aeruginosa
#1
Vanessa Cordeiro Dias, Juliana Alves Resende, André Netto Bastos, Lucas Quinet De Andrade Bastos, Victor Quinet De Andrade Bastos, Ricardo Villela Bastos, Cláudio Galuppo Diniz, Vânia Lúcia Da Silva
Nonfermenting Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii are widespread in the environment and are increasingly associated with nosocomial infections, often associated with multidrug-resistance phenotypes. This study aimed to evaluate epidemiological, physiological, and molecular characteristics of carbapenem resistance in P. aeruginosa and A. baumannii. In total, 63 nonreplicated strains (44 A. baumannii and 19 P. aeruginosa) were isolated from hospitalized patients. Antimicrobial resistance patterns, biocide tolerance, oxidative stress, hemolytic activity, and biofilm formation were assessed...
February 24, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28437231/capsular-polysaccharide-types-and-virulence-related-traits-of-epidemic-kpc-producing-klebsiella-pneumoniae-isolates-in-a-chinese-university-hospital
#2
Yang Liu, Pan-Pan Liu, Lian-Hui Wang, Dan-Dan Wei, La-Gen Wan, Wei Zhang
Klebsiella pneumoniae is an important human pathogen associated with a variety of diseases and the prevalence of blaKPC carrying K. pneumoniae (KPC-Kp) is rapidly increasing. Capsule is an important virulence factor in K. pneumoniae. In this study, we determined to first systematically characterize capsular polysaccharide (CPS) and virulence traits in KPC-Kp strains. A total of 56 KPC-Kp isolates were recovered from clinical samples in a Chinese hospital, which were assigned to clonal lineages by multilocus sequence typing (MLST)...
February 24, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28437227/emergence-of-the-uncommon-clone-st944-st78-carrying-blaoxa-40-like-and-blactx-m-like-genes-among-carbapenem-nonsusceptible-acinetobacter-baumannii-in-moscow-russia
#3
Nikolay Mayanskiy, Igor Chebotar, Natalia Alyabieva, Olga Kryzhanovskaya, Tatiana Savinova, Andrej Turenok, Yulia Bocharova, Anna Lazareva, Svetlana Polikarpova, Olga Karaseva
Carbapenem-nonsusceptible (Carba-NS) Acinetobacter baumannii has emerged as an important cause of nosocomial infections. In the present study, we characterized 91 Carba-NS A. baumannii isolates collected from patients of surgical departments and intensive care units at three hospitals in Moscow in 2012-2015. Multilocus sequence typing (MLST) using the Oxford (Oxf) scheme identified 16 sequence types (STs) of three clonal complexes (CCs), including CC92(Oxf) (67%), CC109(Oxf) (1%), CC944(Oxf) (29%), and the singleton ST1100(Oxf) (3%)...
February 21, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28436830/antimicrobial-activity-of-free-and-liposome-encapsulated-thymol-and-carvacrol-against-salmonella-and-staphylococcus-aureus-adhered-to-stainless-steel
#4
Juliana Both Engel, Caroline Heckler, Eduardo Cesar Tondo, Daniel Joner Daroit, Patrícia da Silva Malheiros
Antimicrobial activity of thymol, carvacrol and thymol/carvacrol liposomes (TCL) was evaluated against two bacterial pools, each one consisting of four strains of Staphylococcus aureus or Salmonella enterica. TCL were prepared using thin-film hydration, showing 270.20nm average diameter (polydispersity index of 0.33) and zeta potential of +39.99mV. Minimum inhibitory concentration (MIC) of thymol, carvacrol and TCL against S. aureus pool was 0.662mg/ml, while MIC for Salmonella pool was 0.331mg/ml for thymol and carvacrol, and for TCL was 0...
April 13, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28436748/disruption-of-tetr-type-regulator-aden-by-mobile-genetic-element-confers-elevated-virulence-in-acinetobacter-baumannii
#5
Rajagopalan Saranathan, Sudhakar Pagal, Ajit R Sawant, Archana Tomar, M Madhangi, Suresh Sah, Annapurna Satti, K P Arunkumar, K Prashanth
Acinetobacter baumannii is an important human pathogen and considered as a major threat due to its extreme drug resistance. In this study, the genome of a hyper-virulent MDR strain PKAB07 of A. baumannii isolated from an Indian patient was sequenced and analysed to understand its mechanisms of virulence, resistance and evolution. Comparative genomics analysis of PKAB07 revealed virulence and resistance related genes scattered throughout the genome, instead of being organized as an island, indicating the highly mosaic nature of the genome...
April 24, 2017: Virulence
https://www.readbyqxmd.com/read/28436329/molecular-mechanisms-underlying-the-function-diversity-of-arsr-family-metalloregulator
#6
Sai Ren, Qiming Li, Longxiang Xie, Jianping Xie
The ArsR family of transcriptional regulators are widespread among microorganisms and are involved in various important cellular events, such as metal ion homeostasis, biofilm formation, primary and secondary metabolism, symbiosis, response to adverse condition, and virulence. Its N-terminus contains a winged helix-turn-helix DNA-binding domain that can repress or activate transcription by binding to downstream target promoters. With the increasing number of members in this family identified over the past few decades, the ArsR family members have been intensively explored...
2017: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/28435840/microbial-flora-probiotics-bacillus-subtilis-and-the-search-for-a-long-and-healthy-human-longevity
#7
COMMENT
Facundo Rodriguez Ayala, Carlos Bauman, Sebastián Cogliati, Cecilia Leñini, Marco Bartolini, Roberto Grau
Probiotics are live microorganisms that have beneficial effects on host health, including extended lifespan, when they are administered or present in adequate quantities. However, the mechanisms by which probiotics stimulate host longevity remain unclear and very poorly understood. In a recent study (Nat. Commun. 8, 14332 (2017) doi: 10.1038/ncomms14332), we used the spore-forming probiotic bacterium Bacillus subtilis and the model organism Caenorhabditis elegans to study the mechanism by which a probiotic bacterium affects host longevity...
March 16, 2017: Microbial Cell
https://www.readbyqxmd.com/read/28435567/role-of-antibiotic-cement-coated-nailing-in-infected-nonunion-of-tibia
#8
C Bhatia, A K Tiwari, S B Sharma, S Thalanki, A Rai
INTRODUCTION: Infected nonunion of long bones is a chronic and debilitating disorder. It is more difficult to deal with when the implant used for internal fixation itself becomes a potential media for infection because of bacterial adhesion and biofilm formation. Traditionally, it is managed by two-stage procedure for controlling the infection first and then treating the nonunion. This study has been undertaken to explore antibiotic cement coated nailing as single stage treatment modality for treating infection and achieving stability at the same time...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435269/efficacy-of-silk-fibroin-nano-silver-against-staphylococcus-aureus-biofilms-in-a-rabbit-model-of-sinusitis
#9
Minghui Jia, Zhongchun Chen, Yongwei Guo, Xin Chen, Xia Zhao
BACKGROUND: Staphylococcus aureus biofilms contribute significantly to the recalcitrant nature of chronic rhinosinusitis. In previous studies, it has been shown that silk fibroin-nano silver solution can eliminate S. aureus biofilms in vitro, which suggests a potential role of this novel agent in the treatment of biofilm-associated diseases, such as sinusitis. OBJECTIVE: The aim of this study was to investigate the efficacy of silk fibroin-nano silver solution as a topical anti-biofilm agent in a rabbit model of sinusitis...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28435260/development-of-gold-nanoparticles-coated-with-silica-containing-the-antibiofilm-drug-cinnamaldehyde-and-their-effects-on-pathogenic-bacteria
#10
Mohankandhasamy Ramasamy, Jin-Hyung Lee, Jintae Lee
Emerging resistance to antibiotics is a mounting worldwide health concern and increases the need for nonantibiotic strategies to combat infectious diseases caused by bacterial pathogens. In this study, the authors used the antibiofilm activity of the naturally occurring antimicrobial cinnamaldehyde (CNMA) conjugated to the surface of gold nanoparticles (GNPs) to deliver CNMA efficiently and eradicate biofilms of Gram-negative organisms (enterohemorrhagic Escherichia coli O157:H7, and Pseudomonas aeruginosa), Gram positive (methicillin-sensitive Staphylococcus aureus organisms, and methicillin-resistant Staphylococcus aureus) bacteria...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28435253/antimicrobial-photodynamic-activity-and-cytocompatibility-of-au25-capt-18-clusters-photoexcited-by-blue-led-light-irradiation
#11
Saori Miyata, Hirofumi Miyaji, Hideya Kawasaki, Masaki Yamamoto, Erika Nishida, Hiroko Takita, Tsukasa Akasaka, Natsumi Ushijima, Toshihiko Iwanaga, Tsutomu Sugaya
Antimicrobial photodynamic therapy (aPDT) has beneficial effects in dental treatment. We applied captopril-protected gold (Au25(Capt)18) clusters as a novel photosensitizer for aPDT. Photoexcited Au clusters under light irradiation generated singlet oxygen ((1)O2). Accordingly, the antimicrobial and cytotoxic effects of Au25(Capt)18 clusters under dental blue light-emitting diode (LED) irradiation were evaluated. (1)O2 generation of Au25(Capt)18 clusters under blue LED irradiation (420-460 nm) was detected by a methotrexate (MTX) probe...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28435190/prevalence-of-salmonella-in-poultry-processing-environments-in-wet-markets-in-penang-and-perlis-malaysia
#12
Hafiz Nidaullah, Nadarajan Abirami, Ahamed Kamal Shamila-Syuhada, Li-Oon Chuah, Huda Nurul, Teik Pei Tan, Farah Wahida Zainal Abidin, Gulam Rusul
AIM: The aim of this study was to determine the prevalence of various Salmonella serotypes in chickens, carcass contact surfaces as well as environmental samples collected from wet markets and small scale processing plant. MATERIALS AND METHODS: A total of 182 poultry and environmental samples were collected at random on separate occasions from wet markets and small scale processing plant, during the period of October 2014 to July 2015 in Penang and Perlis, Malaysia...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28435161/biofilms-communities-in-sync
#13
Shimona Starling
No abstract text is available yet for this article.
April 24, 2017: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/28434823/influence-of-serum-and-polystyrene-plate-type-on-stability-of-candida-albicans-biofilms
#14
Purity N Kipanga, Walter Luyten
Adhesion is a crucial initial step in microbial biofilm formation. Firm attachment to a target surface subsequently ensures successful colonization and survival despite turbulent conditions. In the laboratory, polystyrene plates are commonly used in biofilm experiments and the 'washing/rinse steps' before staining are critical for assaying biofilm viability. However, these rinse steps risk the removal (partially or entirely) of the formed biofilm, resulting in inconsistent results. The aim of the present study was to optimize conditions for firmer biofilms, less prone to disruption and thus significantly reducing well-to-well variability...
April 20, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28434696/complete-eradication-of-biofilm-from-orthopedic-materials
#15
Jeffrey T Leary, Matthew M Werger, William H Broach, Lindsey N Shaw, Brandon G Santoni, Thomas L Bernasek, Steven T Lyons
BACKGROUND: Interest exists in finding alternatives to current management strategies in periprosthetic joint infections, which typically include a 2-stage revision with placement of an antibiotic spacer and delayed placement of a new implant. We studied the efficacy of autoclaving, ultrasonication, and mechanical scrubbing for sterilization and biofilm eradication on infected cobalt-chrome discs. METHODS: Strains of Staphylococcus aureus MRSA252 or Staphylococcus epidermidis RP62A were grown on the discs...
March 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28434686/effects-of-trimethylsilane-plasma-coating-on-the-hydrophobicity-of-denture-base-resin-and-adhesion-of-candida-albicans-on-resin-surfaces
#16
Tianshuang Liu, Changqi Xu, Liang Hong, Franklin Garcia-Godoy, Timothy Hottel, Jegdish Babu, Qingsong Yu
STATEMENT OF PROBLEM: Candida-associated denture stomatitis is the most common oral mucosal lesion among denture wearers. Trimethylsilane (TMS) plasma coating may inhibit the growth of Candida albicans on denture surfaces. PURPOSE: The purpose of this in vitro study was to investigate whether TMS plasma coatings can effectively reduce C albicans adhesion on denture base acrylic resin surfaces. MATERIAL AND METHODS: Sixty denture base acrylic resin disks with smooth and rough surfaces were prepared and were either left untreated (control group) or coated with TMS monomer (experimental group) by using plasma...
April 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28434261/strategies-to-prevent-infections-associated-with-cardiovascular-implantable-electronic-devices
#17
Bharath Raj Palraj, Saira Farid, M Rizwan Sohail
Infections involving cardiovascular implantable electronic devices (CIED) are associated with high morbidity and mortality and substantial financial cost. In the past two decades, the rate of CIED infections has increased disproportionate to the number of devices implanted, likely due to aging patient population with multiple comorbidities. Microbial contamination of the generator pocket and or leads by skin flora at the time of implantation is a major mechanism for early CIED infections. Due to resistance to host immune cells and antibiotics caused by biofilm formation, complete removal of the device generator and leads is required to achieve cure...
April 24, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28433912/achieving-partial-denitrification-through-control-of-biofilm-structure-during-biofilm-growth-in-denitrifying-biofilter
#18
Bin Cui, Xiuhong Liu, Qing Yang, Jianmin Li, Xueyang Zhou, Yongzhen Peng
Partial denitrification was one of most effective ways to provide nitrite for annamox; whereas very limited research has been done to achieve nitrite accumulation in biofilm system. In this study, partial denitrification was studied in a lab-scale denitrifying biofilter (DNBF). The results showed biofilm structure variations caused the differences between nitrate specific reduction rate (NaSRR) and nitrite specific reduction rate (NiSRR), which led to nitrite accumulation in different degree at different biofilm formation phases...
April 10, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28433834/antimicrobial-and-anticancer-photodynamic-activity-of-a-phthalocyanine-photosensitizer-with-n-methyl-morpholiniumethoxy-substituents-in-non-peripheral-positions
#19
Jolanta Dlugaszewska, Wojciech Szczolko, Tomasz Koczorowski, Paulina Skupin-Mrugalska, Anna Teubert, Krystyna Konopka, Malgorzata Kucinska, Marek Murias, Nejat Düzgüneş, Jadwiga Mielcarek, Tomasz Goslinski
Photodynamic therapy involves the use of a photosensitizer that is irradiated with visible light in the presence of oxygen, resulting in the formation of reactive oxygen species. A novel phthalocyanine derivative, the quaternary iodide salt of magnesium(II) phthalocyanine with N-methyl morpholiniumethoxy substituents, was synthesized, and characterized. The techniques used included mass spectrometry (MALDI TOF), UV-vis, NMR spectroscopy, and photocytotoxicity against bacteria, fungi and cancer cells. The phthalocyanine derivative possessed typical characteristics of compounds of the phthalocyanine family but the effect of quaternization was observed on the optical properties, especially in terms of absorption efficiency...
April 8, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28433610/paraoxonases-and-infectious-diseases
#20
REVIEW
Jordi Camps, Simona Iftimie, Anabel García-Heredia, Antoni Castro, Jorge Joven
The paraoxonases (PON1, PON2 and PON3) are an enzyme family with a high structural homology. All of them have lactonase activity and degrade lipid peroxides in lipoproteins and cells. As such, they play a role in protection against oxidation and inflammation. Infectious diseases are often associated with oxidative stress and an inflammatory response. Infection and inflammation trigger a cascade of reactions in the host, known as the acute-phase response. This response is associated with dramatic changes in serum proteins and lipoproteins, including a decrease in serum PON1 activity...
April 19, 2017: Clinical Biochemistry
keyword
keyword
21121
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"