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Cardiac short term memory

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https://www.readbyqxmd.com/read/28985245/heart-rate-variability-and-cognitive-function-in-middle-age-adults-the-coronary-artery-risk-development-in-young-adults
#1
Adina Zeki Al Hazzouri, Tali Elfassy, Mercedes R Carnethon, Donald M Lloyd-Jones, Kristine Yaffe
BACKGROUND: Low heart rate variability (HRV), a marker of cardiac autonomic dysfunction, has been associated with major risk factors of cognitive impairment. Yet, the direct association of HRV with cognitive function remains relatively unexplored, particularly in midlife. METHODS: In 2005, 2 measures of short-term HRV, the SD of normal-to-normal intervals (SDNN) and the root mean square of successive differences (RMSSD), were calculated for participants of the Coronary Artery Risk Development in Young Adults study, and then categorized into quartiles...
July 25, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28947453/association-of-vascular-access-flow-with-short-term-and-long-term-mortality-in-chronic-haemodialysis-patients-a-retrospective-cohort-study
#2
Chung-Kuan Wu, Chia-Lin Wu, Chia-Hsun Lin, Jyh-Gang Leu, Chew-Teng Kor, Der-Cherng Tarng
OBJECTIVES: To investigate the impact of vascular access flow (Qa) on vascular and all-cause mortality in chronic haemodialysis (HD) patients. DESIGN: Observational cohort study. SETTING: Single centre. PARTICIPANTS: Adult chronic HD patients at the HD unit of Shin Kong Wu Ho-Su Memorial Hospital between 1 January 2003 and 31 December 2003 were recruited. Patients were excluded if they had arteriovenous fistula or arteriovenous graft failure within 3 months before the date of Qa measurement, were aged <18 years and had Qa levels of ≥2000mL/min...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28937981/cognitive-function-in-patients-with-stable-coronary-heart-disease-related-cerebrovascular-and-cardiovascular-responses
#3
Mathieu Gayda, Vincent Gremeaux, Louis Bherer, Martin Juneau, Joffrey Drigny, Olivier Dupuy, Gabriel Lapierre, Véronique Labelle, Annik Fortier, Anil Nigam
Chronic exercise has been shown to prevent or slow age-related decline in cognitive functions in otherwise healthy, asymptomatic individuals. We sought to assess cognitive function in a stable coronary heart disease (CHD) sample and its relationship to cerebral oxygenation-perfusion, cardiac hemodynamic responses, and [Formula: see text] peak compared to age-matched and young healthy control subjects. Twenty-two young healthy controls (YHC), 20 age-matched old healthy controls (OHC) and 25 patients with stable CHD were recruited...
2017: PloS One
https://www.readbyqxmd.com/read/28804462/heat-acclimation-mediated-cross-tolerance-origins-in-within-life-epigenetics
#4
REVIEW
Michal Horowitz
The primary outcome of heat acclimation is increased thermotolerance, which stems from enhancement of innate cytoprotective pathways. These pathways produce "ON CALL" molecules that can combat stressors to which the body has never been exposed, via cross-tolerance mechanisms (heat acclimation-mediated cross-tolerance-HACT). The foundation of HACT lies in the sharing of generic stress signaling, combined with tissue/organ- specific protective responses. HACT becomes apparent when acclimatory homeostasis is achieved, lasts for several weeks, and has a memory...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28647182/preoperative-application-of-combination-of-portal-venous-injection-of-donor-spleen-cells-and-intraperitoneal-injection-of-rapamycin-prolongs-the-survival-of-cardiac-allografts-in-mice
#5
Wen-Lin Gong, Chuang Sha, Gang Du, Zhong-Gui Shan, Zhong-Quan Qi, Su-Fang Zhou, Nuo Yang, Yong-Xiang Zhao
OBJECTIVE: To investigate the effects of preoperative portal venous injection of donor spleen cells (PVIDSC) and intraperitoneal injection of rapamycin in the acute rejection of cardiac allograft in mice and the underlying mechanisms. METHODS: Homogenous female B6 mice and BALB/c mice were used as recipients and donors of heart transplantation. These mice were randomly divided into different groups and received PVIDSC alone, rapamycin alone, or PVIDSC and rapamycin combined therapy...
May 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28194440/transient-antibody-targeting-of-cd45rc-induces-transplant-tolerance-and-potent-antigen-specific-regulatory-t-cells
#6
Elodie Picarda, Séverine Bézie, Laetitia Boucault, Elodie Autrusseau, Stéphanie Kilens, Dimitri Meistermann, Bernard Martinet, Véronique Daguin, Audrey Donnart, Eric Charpentier, Laurent David, Ignacio Anegon, Carole Guillonneau
Rat and human CD4(+) and CD8(+) Tregs expressing low levels of CD45RC have strong immunoregulatory properties. We describe here that human CD45 isoforms are nonredundant and identify distinct subsets of cells. We show that CD45RC is not expressed by CD4(+) and CD8(+) Foxp3(+) Tregs, while CD45RA/RB/RO are. Transient administration of a monoclonal antibody (mAb) targeting CD45RC in a rat cardiac allotransplantation model induced transplant tolerance associated with inhibition of allogeneic humoral responses but maintained primary and memory responses against cognate antigens...
February 9, 2017: JCI Insight
https://www.readbyqxmd.com/read/28131874/implicit-activation-of-the-aging-stereotype-influences-effort-related-cardiovascular-response-the-role-of-incentive
#7
Athina Zafeiriou, Guido H E Gendolla
Based on previous research on implicit effects on effort-related cardiovascular response and evidence that aging is associated with cognitive difficulties, we tested whether the mere activation of the aging stereotype can systematically influence young individuals' effort-mobilization during cognitive performance. Young participants performed an objectively difficult short-term memory task during which they processed elderly vs. youth primes and expected low vs. high incentive for success. When participants processed elderly primes during the task, we expected cardiovascular response to be weak in the low-incentive condition and strong in the high-incentive condition...
January 26, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28096845/cognitive-impairment-after-sudden-cardiac-arrest
#8
Magdalena Jaszke-Psonka, Magdalena Piegza, Piotr Ścisło, Robert Pudlo, Jacek Piegza, Karina Badura-Brzoza, Aleksandra Leksowska, Robert T Hese, Piotr W Gorczyca
AIM: To evaluate the incidence and severity of the impairment of selected cognitive functions in patients after sudden cardiac arrest (SCA) in comparison to patients after myocardial infarction without SCA and healthy subjects and to analyze the influence of sociodemographic and clinical parameters and the duration of cardiac arrest on the presence and severity of the described disorders. MATERIAL AND METHODS: The study group comprised 30 cardiac arrest survivors, the reference group comprised 31 survivors of myocardial infarction without cardiac arrest, and the control group comprised 30 healthy subjects...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27595136/glucocorticoids-mediate-short-term-high-fat-diet-induction-of-neuroinflammatory-priming-the-nlrp3-inflammasome-and-the-danger-signal-hmgb1
#9
Julia L Sobesky, Heather M D'Angelo, Michael D Weber, Nathan D Anderson, Matthew G Frank, Linda R Watkins, Steven F Maier, Ruth M Barrientos
The impact of the foods we eat on metabolism and cardiac physiology has been studied for decades, yet less is known about the effects of foods on the CNS, or the behavioral manifestations that may result from these effects. Previous studies have shown that long-term consumption of high-fat foods leading to diet-induced obesity sensitizes the inflammatory response of the brain to subsequent challenging stimuli, causing deficits in the formation of long-term memories. The new findings reported here demonstrate that short-term consumption of a high-fat diet (HFD) produces the same outcomes, thus allowing the examination of mechanisms involved in this process long before obesity and associated comorbidities occur...
July 2016: ENeuro
https://www.readbyqxmd.com/read/27320556/short-term-total-hepatic-vascular-exclusion-in-difficult-caudate-lobe-dissection-in-living-donor-liver-transplantation-recipients
#10
W-F Li, T-L Lin, T-J Tan, R B Alikhanov, C-C Yong, S-H Wang, C-C Lin, Y-W Liu, C-C Wang, C-L Chen
BACKGROUND: Recipient hepatectomy can be complicated by severe bleeding during caudate lobe dissection in living-donor liver transplantation (LDLT), especially when the inferior vena cava is encased or with dense adhesions from prior interventions. Total hepatic vascular exclusion (TVE) including total hepatic inflow (Pringle maneuver) and occlusion of supra- and infra-hepatic inferior vena cava during the partial hepatectomy has been studied well, but it has not been mentioned regarding recipient hepatectomy in LDLT...
May 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27048933/neurologic-and-cognitive-outcomes-after-aortic-arch-operation-with-hypothermic-circulatory-arrest
#11
Paolo Centofanti, Cristina Barbero, Federico D'Agata, Marcella M Caglio, Paola Caroppo, Alessandro Cicerale, Matteo Attisani, Michele La Torre, Alberto Milan, Maria Luisa Contristano, Elena Carlini, Gennaro Izzo, Paolo Mortara, Franco Veglio, Mauro Rinaldi
BACKGROUND: Neurologic injury is still a frequent cause of mortality, morbidity, and long-lasting disability in patients undergoing an aortic arch operation with hypothermic circulatory arrest. The aim of this analysis was to evaluate short- and long-term outcomes in neurologic and cognitive functions in this group of high-risk patients. METHODS: A total of 333 patients undergoing an aortic arch operation between February 2004 and June 2010 were retrospectively reviewed...
September 2016: Surgery
https://www.readbyqxmd.com/read/27032570/monetary-incentive-moderates-the-effect-of-implicit-fear-on-effort-related-cardiovascular-response
#12
RANDOMIZED CONTROLLED TRIAL
Mathieu Chatelain, Guido H E Gendolla
Integrating the implicit-affect-primes-effort model (Gendolla, 2012, 2015) with the principles of motivational intensity theory (Brehm & Self, 1989) we investigated if the effort mobilization deficit observed in people exposed to fear primes (vs. anger primes) in a difficult short-term memory task could be compensated by high monetary incentive. Effort was operationalized as cardiac response. We expected that fear primes should lead to the strongest cardiac pre-ejection period (PEP) reactivity when incentive was high (high subjective demand and high justified effort) and to the weakest response when incentive was low (high subjective demand but only low justified effort)...
May 2016: Biological Psychology
https://www.readbyqxmd.com/read/26857066/durable-benefits-of-cellular-postconditioning-long-term-effects-of-allogeneic-cardiosphere-derived-cells-infused-after-reperfusion-in-pigs-with-acute-myocardial-infarction
#13
Hideaki Kanazawa, Eleni Tseliou, James F Dawkins, Geoffrey De Couto, Romain Gallet, Konstantinos Malliaras, Kristine Yee, Michelle Kreke, Ileana Valle, Rachel R Smith, Ryan C Middleton, Chak-Sum Ho, Rohan Dharmakumar, Debiao Li, Raj R Makkar, Keiichi Fukuda, Linda Marbán, Eduardo Marbán
BACKGROUND: Infusion of allogeneic cardiosphere-derived cells (allo-CDCs) postreperfusion elicits cardioprotective cellular postconditioning in pigs with acute myocardial infarction. However, the long-term effects of allo-CDCs have not been assessed. We performed a placebo-controlled pivotal study for long-term evaluation, as well as shorter-term mechanistic studies. METHODS AND RESULTS: Minipigs underwent 1.5-hour mid-left anterior descending balloon occlusion followed by reperfusion and were randomized to receive intracoronary allo-CDCs or vehicle 30 minutes postreperfusion...
February 8, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/26818636/non-invasive-programmed-stimulation-to-identify-high-risk-patients-with-implanted-cardioverter-defibrillator-the-nips-icd-study-study-protocol-for-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Piotr Futyma, Marian Futyma, Piotr Kułakowski
BACKGROUND: The use of an implantable cardioverter defibrillator (ICD) is a widely used and effective therapy, which reduces the risk of cardiac death in many cardiac diseases, both implanted for secondary and primary prevention. However, recurrent arrhythmias and ICD discharges have adverse prognostic significance. Additional parameters that would identify patients who are at increased risk of arrhythmias and appropriate ICD interventions would be of clinical value. Modern ICDs are relatively complex devices with a number of functions, including the possibility to perform noninvasive programmed stimulation (NIPS) with an implanted electrode located in the right ventricle...
January 27, 2016: Trials
https://www.readbyqxmd.com/read/26607046/the-consequences-of-fetal-growth-restriction-on-brain-structure-and-neurodevelopmental-outcome
#15
REVIEW
Suzanne L Miller, Petra S Huppi, Carina Mallard
Fetal growth restriction (FGR) is a significant complication of pregnancy describing a fetus that does not grow to full potential due to pathological compromise. FGR affects 3-9% of pregnancies in high-income countries, and is a leading cause of perinatal mortality and morbidity. Placental insufficiency is the principal cause of FGR, resulting in chronic fetal hypoxia. This hypoxia induces a fetal adaptive response of cardiac output redistribution to favour vital organs, including the brain, and is in consequence called brain sparing...
February 15, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/26413021/successful-use-of-therapeutic-hypothermia-in-a-pregnant-patient
#16
Kevin N Oguayo, Ola O Oyetayo, David Stewart, Steven M Costa, Richard O Jones
Out-of-hospital cardiac arrest is a leading cause of death in the United States. Pregnant women are not immune to cardiac arrest, and the treatment of such patients can be difficult. Pregnancy is a relative contraindication to the use of therapeutic hypothermia after cardiac arrest. A 20-year-old woman who was 18 weeks pregnant had an out-of-hospital cardiac arrest. Upon her arrival at the emergency department, she was resuscitated and her circulation returned spontaneously, but her score on the Glasgow Coma Scale was 3...
August 2015: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/26362634/small-conductance-calcium-activated-potassium-current-is-activated-during-hypokalemia-and-masks-short-term-cardiac-memory-induced-by-ventricular-pacing
#17
Yi-Hsin Chan, Wei-Chung Tsai, Jum-Suk Ko, Dechun Yin, Po-Cheng Chang, Michael Rubart, James N Weiss, Thomas H Everett, Shien-Fong Lin, Peng-Sheng Chen
BACKGROUND: Hypokalemia increases the vulnerability to ventricular fibrillation. We hypothesize that the apamin-sensitive small-conductance calcium-activated potassium current (IKAS) is activated during hypokalemia and that IKAS blockade is proarrhythmic. METHODS AND RESULTS: Optical mapping was performed in 23 Langendorff-perfused rabbit ventricles with atrioventricular block and either right or left ventricular pacing during normokalemia or hypokalemia. Apamin prolonged the action potential duration (APD) measured to 80% repolarization (APD80) by 26 milliseconds (95% confidence interval [CI], 14-37) during normokalemia and by 54 milliseconds (95% CI, 40-68) during hypokalemia (P=0...
October 13, 2015: Circulation
https://www.readbyqxmd.com/read/26216249/variation-in-parasympathetic-dysregulation-moderates-short-term-memory-problems-in-childhood-attention-deficit-hyperactivity-disorder
#18
Anthony R Ward, Gabriela Alarcón, Joel T Nigg, Erica D Musser
Although attention deficit/hyperactivity disorder (ADHD) is associated with impairment in working memory and short-term memory, up to half of individual children with ADHD perform within a normative range. Heterogeneity in other ADHD-related mechanisms, which may compensate for or combine with cognitive weaknesses, is a likely explanation. One candidate is the robustness of parasympathetic regulation (as indexed by respiratory sinus arrhythmia; RSA). Theory and data suggest that a common neural network is likely tied to both heart-rate regulation and certain cognitive functions (including aspects of working and short-term memory)...
November 2015: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/25970000/double-sequential-defibrillation-for-refractory-ventricular-fibrillation-a-case-report
#19
Aurora M Lybeck, Hawnwan Philip Moy, David K Tan
A 40-year-old male struck his chest against a pole during a basketball game and had sudden out-of-hospital cardiac arrest. After bystander cardiopulmonary resuscitation, fire and emergency medical services personnel provided six defibrillation attempts prior to emergency department arrival. A 7th attempt in the emergency department using a different vector was unsuccessful. On the 8th attempt, using a second defibrillator with defibrillator pads placed adjacent to the primary set of defibrillator pads, two shocks were administered in near simultaneous fashion...
2015: Prehospital Emergency Care
https://www.readbyqxmd.com/read/25596374/cognitive-function-and-health-related-quality-of-life-four-years-after-cardiac-arrest
#20
Eirik Alnes Buanes, Arne Gramstad, Karoline Kjellsdotter Søvig, Karl Ove Hufthammer, Hans Flaatten, Thomas Husby, Jørund Langørgen, Jon-Kenneth Heltne
AIM: Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related quality of life four years after cardiac arrest. METHODS: Thirty cardiac arrest survivors over the age of 18 in cerebral performance category 1 or 2 on hospital discharge completed the EQ-5D-5L and HADS questionnaires prior to cognitive testing using the Cambridge Neuropsychological Test Automated Battery...
April 2015: Resuscitation
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