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https://www.readbyqxmd.com/read/29107040/longitudinal-recovery-and-reduced-costs-after-120-sessions-of-locomotor-training-for-motor-incomplete-spinal-cord-injury
#1
Sarah A Morrison, Douglas Lorenz, Carol P Eskay, Gail F Forrest, D Michele Basso
OBJECTIVE: To determine the impact of long term, body weight supported locomotor training (BWSLT) after chronic, incomplete spinal cord injury (SCI). Also, health care costs were estimated related to lost recovery potential and preventable secondary complications that may have occurred due to visit limits imposed by insurers. DESIGN: Prospective observational cohort with longitudinal follow up. SETTING: Eight outpatient rehabilitation centers that participate in the Christopher & Dana Reeve Foundation NeuroRecovery Network® (NRN)...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28969949/variability-and-comprehensiveness-of-north-american-online-available-physical-therapy-protocols-following-hip-arthroscopy-for-femoroacetabular-impingement-and-labral-repair
#2
Gregory L Cvetanovich, Vincent Lizzio, Fabien Meta, Derek Chan, Ira Zaltz, Shane J Nho, Eric C Makhni
PURPOSE: To assess comprehensiveness and variability of postoperative physical therapy protocols published online following hip arthroscopy for femoroacetabular impingement (FAI) and/or labral repair. METHODS: Surgeons were identified by the International Society for Hip Arthroscopy "Find a Surgeon" feature in North America (http://www.isha.net/members/, search August 10, 2016). Exclusion criteria included nonsurgeons and protocols for conditions other than hip arthroscopy for FAI and/or labral tear...
November 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28900574/a-four-phase-physical-therapy-regimen-for-returning-athletes-to-sport-following-hip-arthroscopy-for-femoroacetabular-impingement-with-routine-capsular-closure
#3
Benjamin D Kuhns, Alexander E Weber, Brian Batko, Shane J Nho, Catherine Stegemann
Hip preservation surgery has become more common over the past decade and is now a preferred treatment modality for an increasingly diverse array of pathology in the young, active patient with hip pain. In particular, hip arthroscopy has become an increasingly popular treatment choice for active patients diagnosed with femoroacetabular impingement (FAI). Appropriate postoperative rehabilitation is critical for overall patient success and optimal long-term outcome. As surgical techniques continue to evolve, rehabilitation protocols must adapt to accommodate changes in the surgical procedure and ultimately provide the safest and fastest recovery of function for the patient...
August 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28817407/nonoperative-management-of-labral-tears-of-the-hip-in-adolescent-athletes-description-of-sports-participation-interventions-comorbidity-and-outcomes
#4
Andrea Cianci, Dai Sugimoto, Andrea Stracciolini, Yi-Meng Yen, Mininder S Kocher, Pierre A dʼHemecourt
CONTEXT: Hip injury among young athletes is increasing, especially hip labral tears. Some tears may require surgical intervention, especially if they are associated with boney pathology such as femoroacetabular impingement (FAI). A protocol for nonoperative treatment of the hip labral tears is not well established. OBJECTIVE: To identify current nonoperative treatment options, comorbidities, sports participation, and outcomes of adolescent athletes who were diagnosed with hip labral tears...
August 16, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28589314/the-health-related-quality-of-life-of-chinese-patients-on-hemodialysis-and-peritoneal-dialysis
#5
Julie Yun Chen, Eric Yuk Fai Wan, Edmond Pui Hang Choi, Anca Ka Chun Chan, Karina Hiu Yen Chan, Joyce Pui Yan Tsang, Cindy Lo Kuen Lam
AIMS: Our aim was to compare health-related quality of life (HRQOL) between end-stage renal disease (ESRD) patients and the Hong Kong general population to identify how the mode of dialysis and other factors were associated with HRQOL. METHODS: We conducted a cross-sectional study involving 253 hemodialysis (HD) patients and 103 peritoneal dialysis (PD) patients recruited in 2014-2015. Their HRQOL was evaluated using Kidney Disease and Quality of Life-36 (KDQOL-36) sub-scale scores and the Short Form-6 Dimensions (SF-6D) health preference score...
December 2017: Patient
https://www.readbyqxmd.com/read/28361441/the-effect-of-a-telephone-based-cognitive-behavioral-therapy-on-quality-of-life-a-randomized-controlled-trial
#6
Fei-Wan Ngai, Paul Wai-Ching Wong, Ka-Fai Chung, Kwok-Yin Leung
Health-related quality of life (HRQoL) has emerged as a major public health concern in perinatal care. The purpose of this study was to examine the effect of telephone-based cognitive behavioral therapy (T-CBT) on HRQoL among Chinese mothers at risk of postnatal depression at 6 weeks and 6 months postpartum. A multi-center randomized controlled trial was conducted at the postnatal units of three regional hospitals. Three hundred and ninety-seven women at risk of postnatal depression were recruited and were randomly assigned to the T-CBT (n = 197) or usual care (n = 200)...
March 30, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28264692/a-three-component-cognitive-behavioural-lifestyle-program-for-preconceptional-weight-loss-in-women-with-polycystic-ovary-syndrome-pcos-a-protocol-for-a-randomized-controlled-trial
#7
RANDOMIZED CONTROLLED TRIAL
G Jiskoot, S H Benneheij, A Beerthuizen, J E de Niet, C de Klerk, R Timman, J J Busschbach, J S E Laven
BACKGROUND: Obesity in women with polycystic ovary syndrome (PCOS) negatively affects all clinical features, and a 5 to 10% weight loss has shown promising results on reproductive, metabolic and psychological level. Incorporating a healthy diet, increasing physical activity and changing dysfunctional thought patterns in women with PCOS are key points in losing weight. The biggest challenge in weight management programs is to achieve a reasonable and sustainable weight loss. The aim of this study is to explore whether Cognitive Behavioural Therapy (CBT) by a mental health professional, working in a multidisciplinary team with a dietician and a physical therapist (a three-component intervention), is more effective for weight loss in the long term, within 12 months...
March 6, 2017: Reproductive Health
https://www.readbyqxmd.com/read/27686411/management-of-a-patient-with-acute-acetabular-labral-tear-and-femoral-acetabular-impingement-with-intra-articular-steroid-injection-and-a-neuromotor-training-program
#8
Joel R Narveson, Matthew D Haberl, Patrick J Grabowski
Study Design Case report. Background Intra-articular hip pathologies can be difficult to diagnose, and evidence to guide physical therapy interventions is lacking. The purpose of this case report is to describe a clinical pathway for conservative management of a patient with an acute acetabular labral tear and femoroacetabular impingement. Case Description The patient was an 18-year-old woman with recent onset of right groin pain who underwent intra-articular corticosteroid injection and therapeutic exercise for the management of an acute acetabular labral tear identified on radiographic imaging...
November 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27629403/the-warwick-agreement-on-femoroacetabular-impingement-syndrome-fai-syndrome-an-international-consensus-statement
#9
D R Griffin, E J Dickenson, J O'Donnell, R Agricola, T Awan, M Beck, J C Clohisy, H P Dijkstra, E Falvey, M Gimpel, R S Hinman, P Hölmich, A Kassarjian, H D Martin, R Martin, R C Mather, M J Philippon, M P Reiman, A Takla, K Thorborg, S Walker, A Weir, K L Bennell
The 2016 Warwick Agreement on femoroacetabular impingement (FAI) syndrome was convened to build an international, multidisciplinary consensus on the diagnosis and management of patients with FAI syndrome. 22 panel members and 1 patient from 9 countries and 5 different specialties participated in a 1-day consensus meeting on 29 June 2016. Prior to the meeting, 6 questions were agreed on, and recent relevant systematic reviews and seminal literature were circulated. Panel members gave presentations on the topics of the agreed questions at Sports Hip 2016, an open meeting held in the UK on 27-29 June...
October 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27594424/ezh2-coupled-with-hotair-to-silence-microrna-34a-by-the-induction-of-heterochromatin-formation-in-human-pancreatic-ductal-adenocarcinoma
#10
Chi-Han Li, Zhangang Xiao, Joanna Hung-Man Tong, Ka-Fai To, Xiangdong Fang, Alfred Sl Cheng, Yangchao Chen
MicroRNA-34a (miR-34a) is frequently downregulated in pancreatic ductal adenocarcinoma (PDAC) cells, however, the silencing mechanism remains unclear. Enhancer of zeste homolog 2 (EZH2) is overexpressed in PDAC, and our previous miRNA profiling showed that inhibition of EZH2 in PDAC cells led to the re-expression of a group of tumor suppressor miRNAs including miR-34a. Here, we studied the effect of ectopic EZH2 expression to the silencing of miR-34a, and identified HOTAIR as an interacting partner to induce heterochromatin formation during miR-34a repression...
January 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27173983/physical-therapy-protocol-after-hip-arthroscopy-clinical-guidelines-supported-by-2-year-outcomes
#11
REVIEW
Benjamin G Domb, Terrance A Sgroi, Jeremy C VanDevender
CONTEXT: Femoroacetabular impingement (FAI) was first described by Ganz in 2003 and is a significant cause of decreased function and mobility. Femoroacetabular impingement must be treated in an individualized, goal-oriented, stepwise fashion. This protocol was developed with biomechanical considerations of soft tissue and bony structures surrounding the hip joint. EVIDENCE ACQUISITION: The PubMed database was searched for scientific and review articles from the years 2000 to 2015 utilizing the search terms: hip rehabilitation, femoroacetabular impingement, and arthroscopy...
July 2016: Sports Health
https://www.readbyqxmd.com/read/27161070/clinical-and-surgical-correlation-of-hip-mr-arthrographic-findings-in-adolescents
#12
Anugayathri Jawahar, Aruna Vade, Laurie Lomasney, Gokcan Okur, Douglas Evans, Perla Subbaiah
OBJECTIVE: The purpose of this study was to analyze the utility of MRA-H in adolescents by comparing the results of imaging with surgical findings and/or clinical outcome. MATERIAL AND METHODS: After obtaining appropriate IRB approval, the Radiologic Information System database was queried for all patients 13-18 years of age who underwent MRA-H from 2004 through 2013. The electronic medical record was reviewed for clinical history, clinical examination findings, and operative notes...
June 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/26978483/evidence-based-clinical-use-of-nanoscale-extracellular-vesicles-in-nanomedicine
#13
Stefano Fais, Lorraine O'Driscoll, Francesc E Borras, Edit Buzas, Giovanni Camussi, Francesco Cappello, Joana Carvalho, Anabela Cordeiro da Silva, Hernando Del Portillo, Samir El Andaloussi, Tanja Ficko Trček, Roberto Furlan, An Hendrix, Ihsan Gursel, Veronika Kralj-Iglic, Bertrand Kaeffer, Maja Kosanovic, Marilena E Lekka, Georg Lipps, Mariantonia Logozzi, Antonio Marcilla, Marei Sammar, Alicia Llorente, Irina Nazarenko, Carla Oliveira, Gabriella Pocsfalvi, Lawrence Rajendran, Graça Raposo, Eva Rohde, Pia Siljander, Guillaume van Niel, M Helena Vasconcelos, María Yáñez-Mó, Marjo L Yliperttula, Natasa Zarovni, Apolonija Bedina Zavec, Bernd Giebel
Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid membranes containing different membrane microdomains such as lipid rafts and caveolae. The most prominent representatives of these so-called extracellular vesicles (EVs) are nanosized exosomes (70-150 nm), which are derivatives of the endosomal system, and microvesicles (100-1000 nm), which are produced by outward budding of the plasma membrane...
April 26, 2016: ACS Nano
https://www.readbyqxmd.com/read/26846934/two-year-outcomes-after-arthroscopic-surgery-compared-to-physical-therapy-for-femoracetabular-impingement-a-protocol-for-a-randomized-clinical-trial
#14
RANDOMIZED CONTROLLED TRIAL
Nancy S Mansell, Daniel I Rhon, Bryant G Marchant, John M Slevin, John L Meyer
BACKGROUND: As the prevalence of hip pathology in the younger athletic population rises, the medical community continues to investigate effective intervention options. Femoracetabular impingement is the morphologically abnormal articulation of the femoral head against the acetabulum, and often implicated in pre-arthritic hip conditions of musculoskeletal nature. Arthroscopic surgical decompression and non-surgical rehabilitation programs focused on strengthening and stability are common interventions...
February 4, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/26816416/conservative-management-of-an-elite-ice-hockey-goaltender-with-femoroacetabular-impingement-fai-a-case-report
#15
Kyle MacIntyre, Brendan Gomes, Steven MacKenzie, Kevin D'Angelo
OBJECTIVE: To detail the presentation of an elite male ice hockey goaltender with cam-type femoroacetabular impingement (FAI) and acetabular labral tears. This case will outline the prevalence, clinical presentation, imaging criteria, pathomechanics, and management of FAI, with specific emphasis on the ice hockey goaltender. CLINICAL FEATURES: A 22-year old retired ice hockey goaltender presented to a chiropractor after being diagnosed by an orthopaedic surgeon with MRI confirmed left longitudinal and chondral flap acetabular labral tears and cam-type femoroacetabular impingement (FAI)...
December 2015: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/26556072/adult-neurogenic-and-antidepressant-effects-of-adiponectin-a-potential-replacement-for-exercise
#16
REVIEW
Ang Li, Suk-Yu Yau, Sergio Machado, Ti-Fei Yuan, Kwok-Fai So
Physical exercise has long been recognized to benefit locomotor and cardiovascular systems. Although an increasing body of evidence also suggests it to be an effective non-medicinal remedy for mental disorders such as depression, the underlying mechanisms remain elusive. A recent study has demonstrated that increases of the adipocyte-secreted hormone adiponectin in the central nervous system following exercise may be responsible for these neuropsychological changes, including enhanced generation of neurons in the adult hippocampus, as well as mitigation of depressive severity...
2015: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/26536659/phosphorylation-of-nucleophosmin-at-threonine-234-237-is-associated-with-hcc-metastasis
#17
Rachel Hiu Ha Ching, Eunice Yuen Ting Lau, Patrick Ming Tat Ling, Joyce Man Fong Lee, Mark Kin Fai Ma, Bowie Yik Ling Cheng, Regina Cheuk Lam Lo, Irene Oi Lin Ng, Terence Kin Wah Lee
Hepatocellular carcinoma (HCC) is frequently complicated by the occurrence of intrahepatic and extrahepatic metastases, leading to poor prognosis. To improve the prognosis for HCC patients, there is an urgent need to understand the molecular mechanisms of metastasis in HCC. Since protein Serine/Threonine phosphorylation emerges to be an important posttranslational modification critical in signaling process associated with cell proliferation, survival and metastasis, we employed a pair of primary tumor-derived and corresponding lung-metastatic counterparts (PLC/PRF/5-PT and PLC/PRF/5-LM) and aimed to identify these changes using CelluSpot Serine/Threonine kinase peptide array...
December 22, 2015: Oncotarget
https://www.readbyqxmd.com/read/26219994/sex-differences-in-patients-with-cam-deformities-with-femoroacetabular-impingement-3-dimensional-computed-tomographic-quantification
#18
Adam B Yanke, M Michael Khair, Robert Stanley, David Walton, Simon Lee, Charles A Bush-Joseph, Alejandro Espinoza Orías, Alejandro A Espinosa Orias, Nozomu Inoue, Shane J Nho
PURPOSE: To determine if significant differences exist between male and female CAM deformities using quantitative 3-dimensional (3D) volume and location analysis. METHODS: Retrospective analysis of preoperative computed tomographic (CT) scans for 138 femurs (69 from male patients and 69 from female patients) diagnosed with impingement from November 2009 to November 2011 was completed. Those patients who presented with hip complaints and had a history, physical examination (limited range of motion, positive impingement signs), plain radiographs (anteroposterior pelvis, 90° Dunn view, false profile view), and magnetic resonance images consistent with femoroacetabular impingement (FAI) and in whom a minimum of 6 months of conservative therapy (oral anti-inflammatory agents, physical therapy, and activity modification) had failed were indicated for arthroscopic surgery and had a preoperative CT scan...
December 2015: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/26004988/androgen-deprivation-therapy-diabetes-and-poor-physical-performance-status-increase-fracture-risk-in-chinese-men-treated-for-prostate-cancer
#19
Jeremy Yuen Chun Teoh, Peter Ka Fung Chiu, Samson Yun Sang Chan, Darren Ming Chun Poon, Ho-Yuen Cheung, Simon See Ming Hou, Chi-Fai Ng
We investigated the fracture risk after androgen deprivation therapy (ADT) for prostate cancer in the Chinese population. All Chinese prostate cancer patients who were treated primarily by radical prostatectomy or radiotherapy, with or without further ADT, from year 2000 to 2009 were reviewed. We compared the fracture risk in patients who were given ADT (ADT group) with those who were not given any ADT (non-ADT group). Potential risk factors including age, diabetes mellitus, hypertension, hyperlipidemia, ischemic heart disease and performance status were reviewed...
2015: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/25853634/vulvodynia-and-concomitant-femoro-acetabular-impingement-long-term-follow-up-after-hip-arthroscopy
#20
Deborah Coady, Stacey Futterman, Dena Harris, Struan H Coleman
OBJECTIVE: We hypothesized that in patients with vulvodynia and femoro-acetabular impingement (FAI), vulvar pain may be generated by the effect of FAI on pelvic floor structures, and treatment with arthroscopy may improve vulvodynia. We also sought to identify characteristics of patients whose vulvodynia improved after arthroscopy. MATERIALS AND METHODS: A case series of patients with vulvodynia and FAI underwent physical therapy, and, if hip symptoms did not improve, arthroscopy...
July 2015: Journal of Lower Genital Tract Disease
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