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https://www.readbyqxmd.com/read/28097676/morbihan-disease-complicated-by-dermatosis-neglecta-a-unique-presentation
#1
Ariel E Eber, Stephanie Mlacker, Sebastian Verne, Robert Griffith, Jennifer Ledon, Marina Perper, Keyvan Nouri, Jeong Hee Cho-Vega
Morbihan disease (MD), also referred to as solid facial edema, or rosacea lymphedema, is a rare disorder that involves chronic erythema and solid edema of the cheeks, eyelids, forehead and glabella and may arise as a complication of acne vulgaris or rosacea. Of note, it may be the only initial presenting symptom of these associated diseases.1,2 Few cases have been described in the literature, since its first description by Robert Degos in 1957. The condition is characterized by its chronicity, a typical clinical appearance, and the lack of specific histopathologic or laboratory findings...
January 18, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28095565/successful-treatment-of-rhinophyma-with-fractionated-carbon-dioxide-co2-laser-in-an-african-american-man-case-report-and-review-of-literature-of-fractionated-co2-laser-treatment-of-rhinophyma
#2
Ekaterina Kraeva, Derek Ho, Jared Jagdeo
Rhinophyma, a late complication of rosacea (phymatous subtype), is a chronic, progressive dermatological condition. The classic pre- sentation of rhinophyma is nodular, thickened skin over the distal nose, and is often accompanied by underlying erythema secondary to in ammation. Due to the unpleasant aesthetic and dis guring appearance, rhinophyma may be associated with a signi cant nega- tive psychosocial impact, resulting in decreased patient quality-of-life. Treatment of rhinophyma is challenging as topical and systemic pharmacotherapies have shown limited ef cacy...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28091390/demodex-spp-infestation-associated-with-treatment-resistant-chalazia-and-folliculitis
#3
Ulviye Güvendi Akçınar, Emine Ünal, Metin Akpınar
Demodecidosis is an ectoparasitosis of pilosebaceous unit caused by demodex mites. The disease may be a primary skin disease or a secondary disease to inflammatory dermatoses such as folliculitis and rosacea. Demodex spp. blepharitis is an infectious ocular disease that is common but always neglected. These mites contain lipase enzymes that help carry bacteria on the surface. The infestation of Demodex spp. has increasingly become a public health concern. A 29-year-old male patient was admitted to our dermatology clinic with a complaint of papules and pustules on his face, which started 4 years ago...
December 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28070633/-acne-and-rosacea-in-pregnancy
#4
REVIEW
S K Bechstein, F Ochsendorf
Acne and rosacea are common chronic inflammatory skin diseases. During pregnancy these skin disorders may become aggravated, in rare cases occurring for the first time. There are no data available for rosacea and little data for acne concerning the course of these skin disorders during pregnancy. Up to 42% of the pregnant women suffer from acne. In 90% of these women the disease existed before pregnancy. In 1/3, however, acne relapsed during pregnancy after a prior disease-free period. In 60% acne deteriorated during pregnancy...
January 9, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28056495/novel-rosaceae-plant-elicitor-peptides-as-sustainable-tools-to-control-xanthomonas-arboricola-pv-pruni-in-prunus-spp
#5
Cristina Ruiz, Anna Nadal, Emilio Montesinos, Maria Pla
Fruit crops are regarded as important health promoters and constitute a major part of global agricultural production, and Rosaceae species are of high economic impact. Their culture is threatened by bacterial diseases, which control is only based on preventive treatment with compounds with limited efficacy and a negative environmental impact. One of the most economically relevant examples is the pathogen Xanthomonas arboricola pv. pruni (Xap) affecting Prunus spp. Plant immune response against pathogens can be triggered and amplified by plant elicitor peptides (Peps), perceived by specific receptors (PEPRs)...
January 5, 2017: Molecular Plant Pathology
https://www.readbyqxmd.com/read/28039671/ocular-acne-rosacea-in-tertiary-eye-center-in-saudi-arabia
#6
Mohammad A Al-Amry, Huda A Al-Ghadeer
PURPOSE: To report the most common presenting signs and symptoms of ocular rosacea for timely diagnosis and management. METHODS: A retrospective chart review of 23 patients with a diagnosis of acne rosacea or a non-specific diagnosis was performed at a tertiary eye hospital. Patients with lid changes such as recurrent blepharitis; meibomianitis; recurrent chalazia; facial skin change such as papules, telangiectatic blood vessels, and/or rhinophyma were included...
December 30, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27997728/azathioprine-induced-rosacea
#7
M Richard, J Seneschal, A Taïeb
In a recent study from our department 7/54 adult atopic dermatitis patients treated with systemic immunosuppressants were referred by ophthalmologists because of severe ocular involvement keratoconjunctivitis with or without keratoconus associated with milder skin symptoms (2). We report the case of a woman affected by atopic dermatitis and asthma in childhood who developed at 63 years of age conjunctivitis associated with blepharitis without causative contact allergen identification at skin testing. She received multiple topical and systemic treatments including cyclosporine 2mg/kg/day stopped after 4 days because of digestive adverse effects...
December 20, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27976437/monitoring-structural-changes-in-demodex-mites-under-topical-ivermectin-in-rosacea-by-means-of-reflectance-confocal-microscopy-a-case-series
#8
LETTER
C Ruini, E Sattler, D Hartmann, M Reinholz, T Ruzicka, T von Braunmühl
No abstract text is available yet for this article.
December 15, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27955934/quality-of-life-in-adults-with-facial-port-wine-stains
#9
Solveig L Hagen, Katherine R Grey, Dorota Z Korta, Kristen M Kelly
BACKGROUND: Facial port-wine stains (PWS) are considered by some an aesthetic skin problem, yet impact on quality of life (QoL) has not been objectively documented. OBJECTIVE: We sought to (1) characterize the effect of PWS on QoL in adults, (2) to identify the clinical and demographic factors that affect QoL, and (3) to compare our results with QoL studies in other skin conditions. METHODS: In total, 244 adults with facial PWS completed an online QoL survey, which included the Skindex-29 instrument...
December 9, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27943234/immune-related-alopecia-areata-and-universalis-type-in-cancer-patients-receiving-immune-checkpoint-inhibitors
#10
A Zarbo, V R Belum, V Sibaud, S Oudard, M A Postow, J J Hsieh, R J Motzer, K J Busam, M E Lacouture
CTLA-4, PD-1, and PD-L1 monoclonal antibodies, commonly known as immune checkpoint inhibitors, are used for the treatment of various malignancies. The mechanism of action involves the inhibition of negative regulators of immune activation, which results in many patients developing immune-related adverse events (irAEs) including endocrinopathies, pneumonitis, colitis, hepatitis and dermatologic events. Dermatologic irAEs include maculopapular rash, pruritus, vitiligo, blistering disorders, mucocutaneous lichenoid eruptions, rosacea, and exacerbation of psoriasis...
December 11, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27942368/rosacea-a-clinical-review
#11
REVIEW
Carsten Sauer Mikkelsen, Helene Ringe Holmgren, Petra Kjellman, Michael Heidenheim, Ari Kappinnen, Peter Bjerring, Theis Huldt-Nystrøm
Rosacea is a field within dermatology with new insight within immunological research and new treatment-algorithm. Patient education on rosacea and appropriate treatments is an important aspect in helping patients succeed with therapy. Treatment should be tailored to each individual patient, taking into account: symptoms, trigger factors, patients' wishes, most bothersome symptoms, psychological aspect, individual needs. A combination of clinical therapies to treat different symptoms concomitantly may offer the best possible outcomes for the patient...
June 15, 2016: Dermatology Reports
https://www.readbyqxmd.com/read/27937005/sorbus-alnifolia-protects-dopaminergic-neurodegeneration-in-caenorhabditis-elegans
#12
Se-Myeong Cheon, Insoo Jang, Myon-Hee Lee, Dae Keun Kim, Hoon Jeon, Dong Seok Cha
CONTEXT: The twigs of Sorbus alnifolia (Sieb. et Zucc.) K. Koch (Rosaceae) have been used to treat neurological disorders as a traditional medicine in Korea. However, there are limited data describing the efficacy of S. alnifolia in Parkinson's disease (PD). OBJECTIVE: This study was conducted to identify the protective effects of the methanol extracts of S. alnifolia (MESA) on the dopaminergic (DA) neurodegeneration in Caenorhabditis elegans. MATERIALS AND METHODS: To test the neuroprotective action of MESA, viability assay was performed after 48 h exposure to 1-methyl-4-phenylpyridine (MMP(+)) in PC12 cells and C...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27933381/genome-wide-identification-and-functional-analysis-of-s-rnase-involved-in-the-self-incompatibility-of-citrus
#13
Mei Liang, Wei Yang, Shiying Su, Lili Fu, Hualin Yi, Chuanwu Chen, Xiuxin Deng, Lijun Chai
S-RNase-based self-incompatibility is found in Solanaceae, Rosaceae, and Scrophulariaceae, and is the most widespread mechanism that prevents self-fertilization in plants. Although 'Shatian' pummelo (Citrus grandis), a traditional cultivated variety, possesses the self-incompatible trait, the role of S-RNases in the self-incompatibility of 'Shatian' pummelo is poorly understood. To identify genes associated with self-incompatibility in citrus, we identified 16 genes encoding homologs of ribonucleases in the genomes of sweet orange (Citrus sinensis) and clementine mandarin (Citrus clementine)...
December 8, 2016: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/27922281/the-effect-of-recurrent-pulsed-dye-laser-treatments-in-rosacea-patients
#14
Mark Strand Do, Gunnar Bergqvist, Shane Griffith, Emma Bergqvist
BACKGROUND: Rosacea is common chronic skin condition and is known to have a negative impact on patient's quality of life. The use of pulsed dye laser treatment to improve quality of life is well documented in the literature. Prior work has emphasized a single series of laser treatments but we investigated the effect of recurrent pulsed dye laser treatment on patient's symptomalology and quality of life. METHODS: We designed an 8 question survey about patient's rosacea symptoms, prior treatments, effectiveness of prior treatments, benefit of the laser treatments, and number of laser treatments...
December 6, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27893539/comparative-efficacy-of-radiofrequency-and-pulsed-dye-laser-in-the-treatment-of-rosacea
#15
Sue-Jeong Kim, Young Lee, Young-Joon Seo, Jeung-Hoon Lee, Myung Im
BACKGROUND: Laser and light-based therapies have been used successfully in the treatment of rosacea; however, evidence is lacking regarding the efficacy of radiofrequency (RF). OBJECTIVE: This study evaluated the efficacy of RF in the treatment of rosacea compared with pulsed dye laser (PDL). METHODS: Thirty patients with rosacea (erythematotelangiectatic rosacea [ETR], n = 20; papulopustular rosacea [PPR], n = 10) were enrolled in a randomized, controlled, split-face study...
November 23, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27891741/combination-treatment-of-propranolol-minocycline-and-tranexamic-acid-for-effective-control-of-rosacea
#16
Hyun Jung Kwon, Joon Hyuk Suh, Eun Jung Ko, Beom Joon Kim
No abstract text is available yet for this article.
November 27, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27879178/-minocycline-induced-hyperpigmentation-not-uncommon-but-nonetheless-important-to-recognise
#17
P J G M Voets, D Blommaert, R R M C Keijsers, H A C Alkemade
BACKGROUND: Minocycline, a broad-spectrum antibiotic from the group of tetracyclins, is frequently prescribed for acne vulgaris and rosacea. Hyperpigmentation is a relatively common side effect of this drug and can lead to multiple unsightly skin lesions, which are not always reversible. It can take a long period, from a few months to several years, before the lesions have completely vanished. CASE DESCRIPTION: A 24-year-old male was seen in our outpatient clinic because of slowly progressive pigmented lesions on his shins...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27878597/the-sweet-cherry-prunus-avium-flowering-locus-t-gene-is-expressed-during-floral-bud-determination-and-can-promote-flowering-in-a-winter-annual-arabidopsis-accession
#18
Antonia Yarur, Esteban Soto, Gabriel León, Andrea Miyasaka Almeida
FT gene is expressed in leaves and buds and is involved in floral meristem determination and bud development in sweet cherry. In woody fruit perennial trees, floral determination, dormancy and bloom, depends on perception of different environmental and endogenous cues which converge to a systemic signaling gene known as FLOWERING LOCUS T (FT). In long-day flowering plants, FT is expressed in the leaves on long days. The protein travels through the phloem to the shoot apical meristem, where it induces flower determination...
December 2016: Plant Reproduction
https://www.readbyqxmd.com/read/27874885/patient-reported-outcomes-of-azelaic-acid-foam-15-for-patients-with-papulopustular-rosacea-secondary-efficacy-results-from-a-randomized-controlled-double-blind-phase-3-trial
#19
Stephen Tyring, James A Solomon, Gerald Staedtler, Jason P Lott, Richard Nkulikiyinka, Kaweh Shakery
Patient-reported treatment outcomes are important for evaluating the impact of drug therapies on patient experience. A randomized, double-blind, vehicle-controlled, parallel-group, multicenter, phase 3 study was conducted in 961 participants to assess patient perception of efficacy, utility, and effect on quality of life (QOL) of an azelaic acid (AzA) 15% foam formulation for the treatment of papulopustular rosacea (PPR). Secondary end points included patient-reported global assessment of treatment response, global assessment of tolerability, and opinion on cosmetic acceptability and practicability of product use...
October 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/27869379/rosacea-management-update-on-general-measures-and-topical-treatment-options
#20
M Schaller, H Schöfer, B Homey, M Hofmann, U Gieler, P Lehmann, T A Luger, T Ruzicka, M Steinhoff
Although there is presently no cure for rosacea, there are several recommended treatment options available to control many of the symptoms and to prevent them from getting worse. In addition to self-help measures like avoidance of trigger factors and proper skin care, rosacea management should include topical medications as one of the first-line choices for patients with erythematous and mild to severe papulopustular rosacea. Since mixed forms of characteristic rosacea symptoms are more common, medical treatment must be symptom-tailored for each individual case and will often involve a combination therapy...
December 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
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