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Lower limb by pass

Gianina Ravenscroft, Nataliya Di Donato, Gabriele Hahn, Mark R Davis, Paul D Craven, Gemma Poke, Katherine R Neas, Teresa M Neuhann, William B Dobyns, Nigel G Laing
Autosomal dominantly inherited mutations of BICD2 are associated with congenital-onset spinal muscular atrophy characterised by lower limb predominance. A few cases have also showed upper motor neuron pathology, including presenting with features resembling hereditary spastic paraplegia. The age-of-onset for the published families is usually at birth but also included cases with childhood- and adult-onset disease. In this report we described two isolated probands that presented in utero with features associated with reduced fetal movements...
September 19, 2016: Neuromuscular Disorders: NMD
Petr Tůma, Martin Jaček, Vladimíra Fejfarová, Jan Polák
An electrophoretic stacking method has been developed for monitoring the therapeutic level of the antibiotic ceftazidime in blood plasma and microdialysates taken from peripheral soft tissues of the lower limbs of patients with diabetic foot syndrome. The biological samples are treated by addition of acetonitrile in an amount of 75% v/v and injected into a capillary in a large volume; after turning on the separation voltage, the residual acetonitrile is forced out of the capillary by the application of hydrodynamic pressure...
October 26, 2016: Analytica Chimica Acta
Mikolaj Walensi, Christian Berg, Michael Piotrowski, Franz-Eduard Brock, Johannes N Hoffmann
The adductor canal compression syndrome is one of the several rare nontraumatic causes of arterial occlusions, which may lead to critical ischemia of the lower limb. We report the case of a 46-year-old athletic woman, who suffered from activity-related paresthesia and sharp pain in the left upper and lower leg for 2 years. Imaging and neurological investigations of the spine remained without pathological findings that would explain the patient's complaints. Actually, the patient presented with symptoms of critical lower limb ischemia...
August 20, 2016: Annals of Vascular Surgery
Fatemeh Pashaei Sabet, Kian Norouzi Tabrizi, Hamid Reza Khankeh, Soheil Saadat, Heidar Ali Abedi, Alireza Bastami
BACKGROUND: Road traffic accident (RTA) victims also suffer from different types of injuries and disabilities, which can affect their quality of life. They usually face with various physical, mental, and social problems. Most traffic accident victims had difficulty to return to normal life. OBJECTIVES: This study aimed to understand the experiences of return to normal life in RTA victims. PATIENTS AND METHODS: This qualitative study with content analysis approach was conducted on 18 Iranian patients with disability in the upper or lower limbs caused by traffic accidents, who had passed a time between 3 months till 2 years...
April 2016: Iranian Red Crescent Medical Journal
Pei-Chen Tsao, Yu-Shih Shiau, Szu-Hui Chiang, Hui-Chen Ho, Yu-Ling Liu, Yuan-Fang Chung, Li-Ju Lin, Ming-Ren Chen, Jia-Kan Chang, Wen-Jue Soong, Hsiu-Lian Lin, Betau Hwang, Kwang-Jen Hsiao
BACKGROUND: Early detection of critical congenital heart disease (CCHD) can significantly reduce morbidity and mortality among newborns. We investigate the feasibility of implementing a community-based newborn CCHD screening program in Taipei. METHODS: Twelve birthing facilities in Taipei participated in a trial screening program between October 1, 2013, and March 31, 2014. Newborns underwent pulse oximetry at 24-36 h old, with probes attached to the right hand and one lower limb...
2016: PloS One
Li Wu, Xian Zhao, He Bo, Zegu Chen, Lin Lu, Hanxiao Wei, Chenglei Zhang, Liu Liu
OBJECTIVE: To investigate the ability of autologous peripheral blood endothelial progenitor cells (EPCs) in promoting neovascularization of tissue engineered bone and osteogenesis of bone marrow mesenchymal stem cells (BMSCs). METHODS: The peripheral blood EPCs and BMSCs from No. 1-9 New Zealand rabbits were isolated, cultured, and identified. According to the cell types, the third generation of cells were divided into 3 groups: EPCs (group A), BMSCs (group B), and co-cultured cells of EPCs and BMSCs (group C, EPCs : BMSCs = 1 : 2)...
January 2016: Chinese Journal of Reparative and Reconstructive Surgery
Adeel Aqil, Anatole Wiik, Michela Zanotto, Victoria Manning, Milad Masjedi, Justin P Cobb
BACKGROUND: Painful unilateral cox arthrosis results in excessive forces passing through the "good leg." The impact of hip arthroplasty on contralateral leg gait has not been fully explored. We measured patients gait before and after arthroplasty, to answer 3 questions: (1) Are peak forces for the good legs outside the normal range? (2) Does arthroplasty protect contralateral limbs by reducing peak forces? and (3) Does arthroplasty result in a more symmetric and normal gait at fast walking speeds? METHODS: This prospective, controlled study, assessed ground reaction forces before and 13 months (range, 6-21 months) after hip arthroplasty...
October 2016: Journal of Arthroplasty
Jowan G Penn-Barwell, Ian D Sargeant
INTRODUCTION: Surgical treatment of high-energy gun-shot wounds (GSWs) to the extremities is challenging. Recent surgical doctrine states that wound tracts from high-energy GSWs should be laid open, however the experience from previous conflicts suggests that some of these injuries can be managed more conservatively. The aim of this study is to firstly characterise the GSW injuries sustained by UK forces, and secondly test the hypothesis that the likely severity of GSWs can be predicted by features of the wound...
May 2016: Injury
Nicolas Bonin, Laurent Jacquot, Laurent Boulard, Patrick Reynaud, Mo Saffarini, Sébastien Lustig
PURPOSE: Various methods exist for measuring limb length and lateralisation after total hip arthroplasty. Most of them utilise standard anteroposterior (AP) pelvic radiographs, but their results can be affected by patient position during imaging and thus the position of the lower limb on the coronal plane. The aim of this study is to evaluate how commonly used measuring methods of limb lengthening and femoral offset are affected by the position of the lower limb in the coronal plane. METHODS: A standing pelvic AP radiograph post implantation of a right total hip prosthesis was digitised...
March 1, 2016: International Orthopaedics
E E F Scott, D F Hamilton, R J Wallace, A Y Muir, A H R W Simpson
OBJECTIVES: Temperature is known to influence muscle physiology, with the velocity of shortening, relaxation and propagation all increasing with temperature. Scant data are available, however, regarding thermal influences on energy required to induce muscle damage. METHODS: Gastrocnemius and soleus muscles were harvested from 36 male rat limbs and exposed to increasing impact energy in a mechanical test rig. Muscle temperature was varied in 5°C increments, from 17°C to 42°C (to encompass the in vivo range)...
February 2016: Bone & Joint Research
Fabrizio Rinaldi, Andrea Galbiati, Sara Marelli, Luigi Ferini Strambi, Marco Zucconi
Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common condition characterized by an irresistible urge to move the legs, concomitant with an unpleasant sensation in the lower limbs, which is typically relieved by movement. Symptoms occur predominantly at rest and prevail in the afternoon or evening. Treatment of patients with RLS/WED is indicated for those patients who suffer from clinically relevant symptoms. The management of mild forms of RLS/WED is mainly based on dopamine agonists (DA) therapy (including pramipexole and ropinirole) and α-2-δ calcium-channel ligand...
February 2016: Current Treatment Options in Neurology
Francesco Falciglia, Alfredo Schiavone Panni, Marco Giordano, Angelo Gabriele Aulisa, Vincenzo Guzzanti
PURPOSE: Management of anterior cruciate ligament injuries in skeletally immature patients (in Tanner stages 2 and 3) is controversial. Conventional reconstruction used in adults can cause iatrogenic growth disturbance due to physeal damage, and studies that report long-term results using a specific technique are scarce. The aim of this study is to evaluate in a large series the mid- and long-term results of a partial transphyseal technique and define the safe percentage of lesions of the femoral growth plate...
March 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Basso Parente, Beatrice Fiorucci, Gioele Simonte, Deborah Maria Brambilla, Massimo Lenti
Osteochondroma is the most common benign tumor of bones in young patients. It is an unusual cause of nonatherosclerotic peripheral arteriopathy. It is mostly detected in youth and, thus, diagnosis can be delayed since symptoms such as claudication can be confused with muscular cramps. In case of clinical suspicion of peripheral artery disease in the young, the presence of an exostosis should be suspected. We reported our experience of 2 young patients with limb ischemia due to ab extrinseco compression of popliteal artery...
April 2016: Annals of Vascular Surgery
Junya Matsumi, Kazuki Tobita, Shigeru Saito
BACKGROUND: The crosser system is useful to treat chronic total occlusion (CTO) lesions refractory to guidewire recanalization. However, the Inter-Society Consensus for the Management of Peripheral Arterial Disease recommends bypass graft surgery for Trans-Atlantic Inter-Society Consensus (TASC) type D femoropopliteal (FP) lesions. This approach may not be practical in patients with previous graft failure. In these patients, endovascular therapy with the crosser system may be appropriate...
April 2016: Annals of Vascular Surgery
Svjetlana Karabuva, Ivana Vrkić, Ivica Brizić, Ivo Ivić, Boris Lukšić
This retrospective study represents observation of 160 children and adolescents aged up to 18 years that experienced venomous snakebites in southern Croatia and were treated in the Clinical Department of Infectious Diseases in the University Hospital Centre Split from 1979 to 2013. The main purpose of this research was to determine the epidemiological characteristics, clinical presentation, local and general complications, and received treatment. Most bites occurred during warm months, from early May to late August (80%), mostly in May and June...
March 15, 2016: Toxicon: Official Journal of the International Society on Toxinology
Kavitha Saravu, Rajagopal Kadavigere, Ananthakrishna Barkur Shastry, Rohit Pai, Chiranjay Mukhopadhyay
UNLABELLED: Two distinct and potentially deceitful cases of neurologic melioidosis are reported. Case 1: A 39-year-old alcoholic and uncontrolled diabetic male presented with cough, fever, and left focal seizures with secondary generalization. An magnetic resonance imaging (MRI) brain scan revealed a small peripherally enhancing subdural collection along the interhemispheric fissure suggestive of minimal subdural empyema. Blood culture grew Burkholderia pseudomallei. Patient was diagnosed with disseminated bacteraemic melioidosis with subdural empyema...
November 2015: Journal of Infection in Developing Countries
Fabio Massimo Francioni, António José Figueiredo, Marco Terribili, Antonio Tessitore
This study aimed to observe the intraseasonal stability of anthropometric, technical and functional test results in academy soccer players of different age categories. In total, 103 participants (age range: 7.7-13.4 years) by 5 age categories of the same academy were recruited for this study. Players were submitted to a field-test battery comprising 3 anthropometric measurements (body mass, stature and body mass index), 6 soccer technical tests (to assess the ability of ball control, ball control with the head, pass accuracy, shooting accuracy, dribbling and dribbling with pass) and 3 functional tests (countermovement jump with the hands on the hip, countermovement jump with free hands and 15-m linear sprint) that was administered in 4 test sessions during the same season...
2016: Journal of Sports Sciences
Jae Ho Chung, Jae Seung Jung, Ho Sung Son, Sung Ho Lee
Percutaneous placement of extracorporeal membrane oxygenation (ECMO) cannulas has many benefits. However, limb ischaemia still remains as an unresolved problem. We experienced an interesting case of limb ischaemia that was caused by external compression of the superficial femoral artery by the venous cannula. A 73-year old woman underwent veno-arterial ECMO due to sudden cardiac arrest with percutaneous femoral cannulations at the right common femoral vein and the left common femoral artery. Three hours after cannulation, the patient's right lower extremity was cool and pale, and the arterial pulses of dorsalis pedis artery and posterior tibial artery were not palpable...
November 2015: Interactive Cardiovascular and Thoracic Surgery
Andrea Maier, Vera Mannartz, Hermann Wasmuth, Christian Trautwein, Ulf-Peter Neumann, Joachim Weis, Joachim Grosse, Matthias Fuest, Max-J Hilz, Joerg B Schulz, Christina Haubrich
Chronic intestinal pseudoobstruction (CIP) can be a severe burden and even a life-threatening disorder. Typically, several years of uncertainty are passing before diagnosis. We are reporting the case of a young woman with a decade of severe, progressive gastrointestinal dysmotility. Unusually, she had also developed an autonomic neuropathy, and a stiff limb syndrome.In addition to achalasia and CIP the young woman also developed neuropathic symptoms: orthostatic intolerance, urinary retention, a Horner syndrome, and lower limb stiffness...
August 2015: Medicine (Baltimore)
Robert Finney, Richard Torbeck, Nazanin Saedi
BACKGROUND AND OBJECTIVES: A 28-year-old female presented with extensive scarring after a traumatic injury to her right lower extremity. She had been hit by a vehicle one year prior to presentation and had several open fractures with extensive overlying cutaneous damage, which required multiple surgeries and skin grafts. She had limited range of motion of the affected limb secondary to scar contracture. STUDY DESIGN/MATERIALS AND METHODS: The patient received 6 treatments with a non-ablative fractional resurfacing (NAFR) device with two wavelengths (Fraxel DUAL, Solta Medical, Hayward, CA) spaced 4-8 weeks apart...
February 2016: Lasers in Surgery and Medicine
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