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https://www.readbyqxmd.com/read/27623692/immunocap%C3%A2-isac-and-microtest-for-multiplex-allergen-testing-in-people-with-difficult-to-manage-allergic-disease-a-systematic-review-and-cost-analysis
#1
Marie Westwood, Bram Ramaekers, Shona Lang, Nigel Armstrong, Caro Noake, Shelley de Kock, Manuela Joore, Johan Severens, Jos Kleijnen
BACKGROUND: Allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. Foreign substances that provoke allergies are called allergens. It has been claimed that multiplex allergen testing may help in diagnosing the cause of symptoms in patients with an unclear cause of allergy or who are allergic to more than one substance. OBJECTIVES: To evaluate multiplex allergen testing [devices that can measure the presence of multiple immunoglobulin E (IgE) antibodies in a patient's blood at the same time], by assessing (1) clinical effectiveness (allergy symptoms, incidence of acute exacerbations, mortality, adverse events of testing and treatment, health-care presentations or admissions, health-related quality of life); (2) effects on treatment (diet, immunotherapy medications, other potential testing); (3) any additional diagnostic information provided by multiplex allergen testing; and (4) cost-effectiveness (cost of different assessment strategies)...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27578263/external-drains-versus-no-drains-after-burr-hole-evacuation-for-the-treatment-of-chronic-subdural-haematoma-in-adults
#2
REVIEW
Deqing Peng, Yongjian Zhu
BACKGROUND: Chronic subdural haematoma (CSDH) is one of the most common types of intracranial haematoma, and often occurs in older people. Burr-hole craniostomy, which is an evacuation through one or two burr holes drilled over the site of the haematoma, has been widely accepted as the most effective way to manage CSDH. Recurrences are a major problem and need reoperation, sometimes repeatedly. OBJECTIVES: To assess the effects and safety of the use of external drains versus no drains after burr-hole evacuation for the treatment of CSDH in adults...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27513591/isolation-as-a-strategy-for-controlling-the-transmission-of-hepatitis-c-virus-hcv-infection-in-haemodialysis-units
#3
REVIEW
Jessica I Bravo Zuñiga, César Loza Munárriz, Jesús López-Alcalde
BACKGROUND: The hepatitis C virus (HCV) infection affects about 2% of the world's population and can cause chronic liver infection and persistent long-term sequelae such as cirrhosis and liver cancer.The prevalence of HCV infection among people on haemodialysis is often higher than the general population. The virus is easily transmitted parenterally, and blood transfusions have previously played a significant role in transmission; however, erythropoietin therapy has reduced the need for transfusions, and coupled with improved screening of donated blood, has significantly decreased transmission by transfusion...
August 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27427192/systematic-review-of-the-magnitude-of-change-in-prevalence-and-quantity-of-salmonella-after-administration-of-pathogen-reduction-treatments-on-pork-carcasses
#4
Sarah C Totton, Julie M Glanville, Rungano S Dzikamunhenga, James S Dickson, Annette M O'Connor
OBJECTIVE: In this systematic review, we summarized change in Salmonella prevalence and/or quantity associated with pathogen reduction treatments (washes, sprays, steam) on pork carcasses or skin-on carcass parts in comparative designs (natural or artificial contamination). METHODS: In January 2015, CAB Abstracts (1910-2015), SCI and CPCI-Science (1900-2015), Medline® and Medline® In-Process (1946-2015) (OVIDSP), Science.gov, and Safe Pork (1996-2012) were searched with no language or publication type restrictions...
June 2016: Animal Health Research Reviews
https://www.readbyqxmd.com/read/27364851/technological-aids-for-the-rehabilitation-of-memory-and-executive-functioning-in-children-and-adolescents-with-acquired-brain-injury
#5
REVIEW
Mark Linden, Carol Hawley, Bronagh Blackwood, Jonathan Evans, Vicki Anderson, Conall O'Rourke
BACKGROUND: The use of technology in healthcare settings is on the increase and may represent a cost-effective means of delivering rehabilitation. Reductions in treatment time, and delivery in the home, are also thought to be benefits of this approach. Children and adolescents with brain injury often experience deficits in memory and executive functioning that can negatively affect their school work, social lives, and future occupations. Effective interventions that can be delivered at home, without the need for high-cost clinical involvement, could provide a means to address a current lack of provision...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27209320/the-magnitude-and-mechanisms-of-the-weekend-effect-in-hospital-admissions-a-protocol-for-a-mixed-methods-review-incorporating-a-systematic-review-and-framework-synthesis
#6
Yen-Fu Chen, Amunpreet Boyal, Elizabeth Sutton, Xavier Armoiry, Samuel Watson, Julian Bion, Carolyn Tarrant
BACKGROUND: Growing literature has demonstrated that patients admitted to hospital during weekends tend to have less favourable outcomes, including increased mortality, compared with similar patients admitted during weekdays. Major policy interventions such as the 7-day services programme in the UK NHS have been initiated to reduce this weekend effect, although the mechanisms behind the effect are unclear. Here, we propose a mixed methods review to systematically examine the literature surrounding the magnitude and mechanisms of the weekend effect...
2016: Systematic Reviews
https://www.readbyqxmd.com/read/27163343/lateral-flow-urine-lipoarabinomannan-assay-for-detecting-active-tuberculosis-in-hiv-positive-adults
#7
REVIEW
Maunank Shah, Colleen Hanrahan, Zhuo Yu Wang, Nandini Dendukuri, Stephen D Lawn, Claudia M Denkinger, Karen R Steingart
BACKGROUND: Rapid detection of tuberculosis (TB) among people living with human immunodeficiency virus (HIV) is a global health priority. HIV-associated TB may have different clinical presentations and is challenging to diagnose. Conventional sputum tests have reduced sensitivity in HIV-positive individuals, who have higher rates of extrapulmonary TB compared with HIV-negative individuals. The lateral flow urine lipoarabinomannan assay (LF-LAM) is a new, commercially available point-of-care test that detects lipoarabinomannan (LAM), a lipopolysaccharide present in mycobacterial cell walls, in people with active TB disease...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27056305/safety-and-efficacy-of-new-generation-drug-eluting-stents-in-women-undergoing-complex-percutaneous-coronary-artery-revascularization-from-the-win-des-collaborative-patient-level-pooled-analysis
#8
Gennaro Giustino, Usman Baber, Melissa Aquino, Samantha Sartori, Gregg W Stone, Martin B Leon, Philippe Genereux, George D Dangas, Jaya Chandrasekhar, Takeshi Kimura, Olga Salianski, Giulio G Stefanini, P Gabriel Steg, Stephan Windecker, William Wijns, Patrick W Serruys, Marco Valgimigli, Marie-Claude Morice, Edoardo Camenzind, Giora Weisz, Pieter C Smits, David E Kandzari, Soren Galatius, Clemens Von Birgelen, Robert Saporito, Raban V Jeger, Ghada W Mikhail, Dipti Itchhaporia, Laxmi Mehta, Rebecca Ortega, Hyo-Soo Kim, Adnan Kastrati, Alaide Chieffo, Roxana Mehran
OBJECTIVES: The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI). BACKGROUND: Whether the benefits of new-generation DES are preserved in women undergoing complex percutaneous revascularization is unknown. METHODS: We pooled patient-level data from women enrolled in 26 randomized trials of DES...
April 11, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/26998683/exercise-based-cardiac-rehabilitation-for-adults-after-heart-valve-surgery
#9
REVIEW
Kirstine L Sibilitz, Selina K Berg, Lars H Tang, Signe S Risom, Christian Gluud, Jane Lindschou, Lars Kober, Christian Hassager, Rod S Taylor, Ann-Dorthe Zwisler
BACKGROUND: Exercise-based cardiac rehabilitation may benefit heart valve surgery patients. We conducted a systematic review to assess the evidence for the use of exercise-based intervention programmes following heart valve surgery. OBJECTIVES: To assess the benefits and harms of exercise-based cardiac rehabilitation compared with no exercise training intervention, or treatment as usual, in adults following heart valve surgery. We considered programmes including exercise training with or without another intervention (such as a psycho-educational component)...
March 21, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26880401/persistent-inflammation-and-recovery-after-intensive-care-a-systematic-review
#10
David M Griffith, Matthew E Vale, Christine Campbell, Steff Lewis, Timothy S Walsh
PURPOSE: Physical weakness is common after critical illness; however, it is not clear how best to treat it. Inflammation characterizes critical illness, is associated with loss of muscle mass during critical illness, and potentially modifies post-intensive care unit (ICU) recovery. We sought to identify published reports on the prevalence of systemic inflammation after critical illness and its association with physical recovery. METHODS: This is a systematic review of the literature from MEDLINE, EMBASE, CINAHL, CPCI-SSH, and CPCI-S from January 1982 to December 2011...
June 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/26568111/surgical-versus-non-surgical-management-of-abdominal-injury
#11
REVIEW
Angela Oyo-Ita, Paul Chinnock, Ikpeme A Ikpeme
BACKGROUND: Injury to the abdomen can be blunt or penetrating. Abdominal injury can damage internal organs such as the liver, spleen, kidneys, intestine, and large blood vessels. There are controversies about the best approach to manage abdominal injuries. OBJECTIVES: To assess the effects of surgical and non-surgical interventions in the management of abdominal trauma in a haemodynamically stable and non-peritonitic abdomen. SEARCH METHODS: We searched the Cochrane Injuries Group's Specialised Register, The Cochrane Library, Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R), EMBASE Classic+EMBASE (Ovid), ISI WOS (SCI-EXPANDED, SSCI, CPCI-S & CPSI-SSH), CINAHL Plus (EBSCO), and clinical trials registers, and screened reference lists...
November 13, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26522651/routine-intracranial-pressure-monitoring-in-acute-coma
#12
REVIEW
Rob J Forsyth, Joseph Raper, Emma Todhunter
BACKGROUND: We know that the brain damage resulting from traumatic and other insults is not due solely to the direct consequences of the primary injury. A significant and potentially preventable contribution to the overall morbidity arises from secondary hypoxic-ischaemic damage. Brain swelling accompanied by raised intracranial pressure (ICP) prevents adequate cerebral perfusion with well-oxygenated blood.Detection of raised ICP could be useful in alerting clinicians to the need to improve cerebral perfusion, with consequent reductions in brain injury...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26445202/implantable-defibrillators-versus-medical-therapy-for-cardiac-channelopathies
#13
REVIEW
David A McNamara, Jeffrey J Goldberger, Mark A Berendsen, Mark D Huffman
BACKGROUND: Sudden cardiac death is a significant cause of mortality in both the US and globally. However, 5% to 15% of people with sudden cardiac death have no structural abnormalities, and most of these events are attributed to underlying cardiac ion channelopathies. Rates of cardiac ion channelopathy diagnosis are increasing. However, the optimal treatment for such people is poorly understood and current guidelines rely primarily on expert opinion. OBJECTIVES: To compare the effect of implantable cardioverter defibrillators (ICD) with antiarrhythmic drugs or usual care in reducing the risk of all-cause mortality, fatal and non-fatal cardiovascular events, and adverse events in people with cardiac ion channelopathies...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26389791/vitamin-k-for-the-primary-prevention-of-cardiovascular-disease
#14
REVIEW
Louise Hartley, Christine Clar, Obadah Ghannam, Nadine Flowers, Saverio Stranges, Karen Rees
BACKGROUND: A deficiency in vitamin K has been associated with increased calcium deposition and coronary artery calcification, which may lead to cardiovascular disease. OBJECTIVES: To determine the effectiveness of vitamin K supplementation as a single nutrient supplement for the primary prevention of cardiovascular disease. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL, Issue 8 of 12, 2014); MEDLINE (Ovid, 1946 to September week 2 2014); EMBASE Classic + EMBASE (Ovid, 1947 to September 18 2014); Science Citation Index Expanded (SCI-EXPANDED) and Conference Proceedings Citation Index, Science (CPCI-S) (both 1990 to 17 September 2014) on Web of Science (Thomson Reuters); Database of Abstracts of Reviews of Effects (DARE); Health Technology Assessment Database and Health Economics Evaluations Database (Issue 3 of 4, 2014)...
September 21, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26368505/emergency-ultrasound-based-algorithms-for-diagnosing-blunt-abdominal-trauma
#15
REVIEW
Dirk Stengel, Grit Rademacher, Axel Ekkernkamp, Claas Güthoff, Sven Mutze
BACKGROUND: Ultrasonography (performed by means of a four-quadrant, focused assessment of sonography for trauma (FAST)) is regarded as a key instrument for the initial assessment of patients with suspected blunt abdominal and thoraco-abdominal trauma in the emergency department setting. FAST has a high specificity but low sensitivity in detecting and excluding visceral injuries. Proponents of FAST argue that ultrasound-based clinical pathways enhance the speed of primary trauma assessment, reduce the number of unnecessary multi-detector computed tomography (MDCT) scans, and enable quicker triage to surgical and non-surgical care...
September 14, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26301722/non-operative-management-versus-operative-management-in-high-grade-blunt-hepatic-injury
#16
REVIEW
Roberto Cirocchi, Stefano Trastulli, Eleonora Pressi, Eriberto Farinella, Stefano Avenia, Carlos Hernando Morales Uribe, Ana Maria Botero, Luis M Barrera
BACKGROUND: Surgery used to be the treatment of choice in cases of blunt hepatic injury, but this approach gradually changed over the last two decades as increasing non-operative management (NOM) of splenic injury led to its use for hepatic injury. The improvement in critical care monitoring and computed tomographic scanning, as well as the more frequent use of interventional radiology techniques, has helped to bring about this change to non-operative management. Liver trauma ranges from a small capsular tear, without parenchymal laceration, to massive parenchymal injury with major hepatic vein/retrohepatic vena cava lesions...
August 24, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26222250/surgical-versus-nonsurgical-interventions-for-flail-chest
#17
REVIEW
Antonio José Maria Cataneo, Daniele C Cataneo, Frederico H S de Oliveira, Karine A Arruda, Regina El Dib, Paulo Eduardo de Oliveira Carvalho
BACKGROUND: Thoracic trauma (TT) is common among people with multiple traumatic injuries. One of the injuries caused by TT is the loss of thoracic stability resulting from multiple fractures of the rib cage, otherwise known as flail chest (FC). A person with FC can be treated conservatively with orotracheal intubation and mechanical ventilation (internal pneumatic stabilization) but may also undergo surgery to fix the costal fractures. OBJECTIVES: To evaluate the effectiveness and safety of surgical stabilization compared with clinical management for people with FC...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26215747/viscoelastic-point-of-care-testing-to-assist-with-the-diagnosis-management-and-monitoring-of-haemostasis-a-systematic-review-and-cost-effectiveness-analysis
#18
REVIEW
Penny Whiting, Maiwenn Al, Marie Westwood, Isaac Corro Ramos, Steve Ryder, Nigel Armstrong, Kate Misso, Janine Ross, Johan Severens, Jos Kleijnen
BACKGROUND: Patients with substantive bleeding usually require transfusion and/or (re-)operation. Red blood cell (RBC) transfusion is independently associated with a greater risk of infection, morbidity, increased hospital stay and mortality. ROTEM (ROTEM® Delta, TEM International GmbH, Munich, Germany; www.rotem.de), TEG (TEG® 5000 analyser, Haemonetics Corporation, Niles, IL, USA; www.haemonetics.com) and Sonoclot (Sonoclot® coagulation and platelet function analyser, Sienco Inc...
July 2015: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/26193704/buflomedil-for-acute-ischaemic-stroke
#19
REVIEW
Simiao Wu, Quantao Zeng, Ming Liu, Jie Yang, Sha He, Sen Lin, Bo Wu
BACKGROUND: Few strategies are effective for the treatment of acute ischaemic stroke. Buflomedil is a vasoactive agent that has been used for peripheral arterial diseases. Research studies have suggested that buflomedil may have beneficial effects in people with cerebral vascular diseases, including acute ischaemic stroke, however it has not been approved for treating stroke in clinical practice. OBJECTIVES: To assess the efficacy and safety of buflomedil for the treatment of acute ischaemic stroke...
July 20, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26064249/longitudinal-analysis-of-meta-analysis-literatures-in-the-database-of-isi-web-of-science
#20
Changtai Zhu, Ting Jiang, Hao Cao, Wenguang Sun, Zhong Chen, Jinming Liu
The meta-analysis is regarded as an important evidence for making scientific decision. The database of ISI Web of Science collected a great number of high quality literatures including meta-analysis literatures. However, it is significant to understand the general characteristics of meta-analysis literatures to outline the perspective of meta-analysis. In this present study, we summarized and clarified some features on these literatures in the database of ISI Web of Science. We retrieved the meta-analysis literatures in the database of ISI Web of Science including SCI-E, SSCI, A&HCI, CPCI-S, CPCI-SSH, CCR-E, and IC...
2015: International Journal of Clinical and Experimental Medicine
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