Read by QxMD icon Read

Peritoneal cycler

Tabo Sikaneta, George Wu, Mohamed Abdolell, Anita Ng, Sara Mahdavi, Anton Svendrovski, Tony Tu, Trish Mercer, Matthew Tong, Dimitrios Oreopoulos, Paul Tam
UNLABELLED:BACKGROUND AND OBJECTIVE: Residual renal function (RRF) correlates with mortality and morbidity rates in patients receiving peritoneal dialysis (PD). We examined the effect of a biocompatible PD solution (Gambrosol Trio; Gambro Lundia AB, Lund, Sweden) with lower concentrations of glucose degradation products on rates of decline in RRF. ♦ DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS: Incident patients at 2 centers in Canada and 1 in Hong Kong were randomized (by minimization) in an open-label parallel group trial to receive Gambrosol Trio or standard PD solution (Dianeal; Baxter Healthcare, Mississauga, Canada) for 2 years...
September 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Lynn Redahan, Andrew Davenport
INTRODUCTION: CA125 in peritoneal dialysis (PD) effluent dialysate has been used as a surrogate biomarker for the health of the peritoneum in PD patients. However CA125 is synthesised by epithelial cells and as such is not specific for the peritoneum, and most studies have only measured peritoneal CA125, without serum CA125 values. As such we wished to determine the factors which influenced PD effluent CA125 in a large contemporaneous cohort. METHODS: We measured dialysate effluent CA125 in PD patients attending for routine assessment of peritoneal membrane function with a peritoneal equilibration test (PET), with corresponding serum CA125...
June 2016: Journal of Nephrology
Nicanor Vega-Diaz, Fayna Gonzalez-Cabrera, Silvia Marrero-Robayna, Raquel Santana-Estupiñan, Roberto Gallego-Samper, Fernando Henriquez-Palop, Patricia Perez-Borges, José Carlos Rodriguez-Perez
BACKGROUND: In order to reduce the cardiovascular risk, morbidity and mortality of peritoneal dialysis (PD), a minimal level of small-solute clearances as well as a sodium and water balance are needed. The peritoneal dialysis solutions used in combination have reduced the complications and allow for a long-time function of the peritoneal membrane, and the preservation of residual renal function (RRF) in patients on peritoneal dialysis (PD) is crucial for the maintenance of life quality and long-term survival...
2015: Journal of Clinical Medicine
Cecile Courivaud, Andrew Davenport
UNLABELLED:BACKGROUND: Interventional trials failed to demonstrate that increasing urea clearance improved peritoneal dialysis (PD) patient survival. Hyperphosphatemia is a well-recognized predictor of cardiovascular and all-cause mortality in PD patients. Simplification of PD small solute clearance targets focuses away from larger solutes, including phosphate. In the US and UK, increasing use of automated peritoneal dialysis (APD) cyclers with shorter dwell times could also potentially reduce peritoneal phosphate removal compared to continuous ambulatory peritoneal dialysis (CAPD)...
January 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Thyago Proença de Moraes, Maria Cláudia Cruz Andreoli, Maria Eugênia Canziani, Dirceu Reis da Silva, Jacqueline Costa Teixeira Caramori, Daniela Ponce, Hélio Vida Cassi, Kleyton de Andrade Bastos, Danyelle Romana Alves Rio, Sergio Wyton Pinto, Sebastião Rodrigues Ferreira Filho, Ludimila Guedim de Campos, Marcia Olandoski, José Carolino Divino-Filho, Roberto Pecoits-Filho
BACKGROUND: Insulin resistance is a common risk factor in chronic kidney disease patients contributing to the high cardiovascular burden, even in the absence of diabetes. Glucose-based peritoneal dialysis (PD) solutions are thought to intensify insulin resistance due to the continuous glucose absorption from the peritoneal cavity. The aim of our study was to analyse the effect of the substitution of glucose for icodextrin on insulin resistance in non-diabetic PD patients in a multicentric randomized clinical trial...
November 2015: Nephrology, Dialysis, Transplantation
Rafia I Chaudhry, Thomas A Golper
Peritoneal dialysis (PD) is a widely accepted and increasingly popular form of dialysis. The invention and technological advancement of the PD cycler further makes PD a convenient option. Prescription-specific parameters are entered into the cycler, which then automatically carries out the steps involved in continuous cycling PD. We review the basics, technical aspects, challenges, and advancements of the cycler.
2015: Medical Devices: Evidence and Research
Michel Fischbach, Ariane Zaloszyc, Betti Schaefer, Claus Schmitt
Conventional automated peritoneal dialysis (APD) is prescribed as a repetition of the same dwell time and the same fill volume delivered by the cycler during the dialysis session. Nevertheless, it is well recognized that a cycle with a short dwell time and a small fill volume favors ultrafiltration (UF), while a cycle with a long dwell time and a large fill volume favors uremic toxin removal. The use of varied dwell times and dwell volumes, called adapted APD, allows for an optimized peritoneal dialysis prescription with better volume control--that is, both an increased UF volume at a lower metabolic cost [UF per gram of glucose absorbed (mL/g)] and increased dialytic sodium removal resulting in improved removal of uremic toxins (urea, creatinine, phosphate) during dialysis...
2014: Advances in Peritoneal Dialysis
Kashyap Patel, Craig R Rayner, Mylène Giraudon, Mohamed A Kamal, Peter N Morcos, Richard Robson, Carl M Kirkpatrick
AIMS: Patients with end-stage renal disease (ESRD) are at increased risk of developing complications associated with influenza infection. Oseltamivir is indicated for influenza treatment in ESRD patients, but the disposition is poorly understood in this patient population. This study aimed to characterize the pharmacokinetics and tolerability of oseltamivir in automated peritoneal dialysis (APD) and construct a pharmacokinetic model to assist with optimized dosing. METHODS: Ten adults with ESRD were prescribed an aggressive APD regimen consisting of three continuous cycler-assisted peritoneal dialysis (CCPD) sessions during the day and two continuous ambulatory (CAPD) sessions overnight...
April 2015: British Journal of Clinical Pharmacology
Borut Cižman, Steve Lindo, Brian Bilionis, Ira Davis, Aaron Brown, Jennifer Miller, Gerald Phillips, Alex Kriukov, James A Sloand
UNLABELLED: BACKGROUND, OBJECTIVES AND METHODS: Increased intraperitoneal volume (IIPV) can occur during automated peritoneal dialysis (APD). The contribution of factors such as cycler programming and patient/user actions to IIPV has not been previously explored. The relationship between IIPV and cycler programming, patient/user actions, and ultrafiltration over a two-year period was investigated using US data from Baxter cyclers. Drain/fill volume ratios of > 1.6 to ≤ 2.0 and > 2...
June 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Katie E Cardone, Wen Zhen Chen, Darren W Grabe, Amber Batzold, Harold J Manley, Thomas P Lodise
OBJECTIVES: The intent of this study was to evaluate the appropriateness of commonly used intravenous (iv) vancomycin dosing schemes in patients on automated peritoneal dialysis (APD) using population pharmacokinetic (PK) modelling and Monte Carlo simulation. METHODS: Data from a single-dose PK study of 10 non-infected APD patients ≥18 years old were analysed. Patients received iv vancomycin (15 mg/kg) followed by three cycler-assisted APD dwells over 8 h, followed by two 8 h dwells...
July 2014: Journal of Antimicrobial Chemotherapy
Poyyapakkam Srivaths, Rajesh Krishnamurthy, Lori Brunner, Barbara Logan, Michael Bennett, Qing Ma, Rene VanDeVoorde, Stuart L Goldstein
BACKGROUND: Children receiving maintenance dialysis exhibit high cardiovascular (CV) associated mortality. We and others have shown high prevalence of cardiac calcifications (CC) in children with endstage renal disease (ESRD). However, no pediatric study has examined modality difference in CC prevalence. The current study was conducted to assess for a difference in CC prevalence between hemodialysis (HD) and peritoneal dialysis (PD) in children with ESRD. METHODS: 38 patients (19 female, 19 male; mean age 15...
April 2014: Clinical Nephrology
Ruben Torres, Marcela Gonzalez, Maria Sanhueza, Erico Segovia, Miriam Alvo, Walter Passalacqua, Antonio Saffie, Leticia Elgueta, Maria Diaz, Francisco Silva
No abstract text is available yet for this article.
May 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Catherine A Firanek, James A Sloand, Lucy B Todd
In the United States, the majority of patients on peritoneal dialysis (PD) use a cycler or automated peritoneal dialysis (APD). The aim of this study was the identification of common features in nurse-led APD training programs that were likely to contribute to successful home dialysis. This study collected data on nurse-led APD training programs in six high-performing PD centers. A 13-point survey, which focused on training tools, topics covered methods used, and level of support at home, was administered during group face-to-face interviews with the PD training nurses...
November 2013: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
C T Chao, P H Hung, J W Huang, H B Tsai
No abstract text is available yet for this article.
January 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Cassiana Regina Góes, Marina Nogueira Berbel, Andre Luis Balbi, Daniela Ponce
During the 1970s and 1980s, peritoneal dialysis (PD) was widely accepted as the standard treatment for acute kidney injury (AKI). However, advances in the techniques of extracorporeal blood purification gradually reduced its use, making PD an underused modality in this context. Although PD for AKI is an underutilized modality worldwide, it is frequently used in developing countries because of its lower cost and minimal infrastructure requirements. Recent studies have shown that PD administered continuously through a flexible catheter and cycler is an effective treatment in AKI because it ensures adequate fluid status and metabolic control...
July 2015: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Judith Bernardini, Diane J Davis
UNLABELLED:BACKGROUND: Training patients to perform peritoneal dialysis (PD) at home is key to good patient outcomes. Currently, no validated curriculum based on education concepts is available in the public domain, and training is not standardized. Few nurses are prepared to be effective trainers. The present study was designed to evaluate the efficiency and effectiveness of PD training using a new cycler designed with animation, visual images, and voice cues and provided by a qualified PD nurse with a standardized script to guide the trainer...
January 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Nadear Elmahi, Eva Csongrádi, Kenneth Kokko, Jack R Lewin, Jamie Davison, Tibor Fülöp
Immunosuppression (IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function (RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis (PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation...
June 24, 2013: World Journal of Transplantation
Dalia Jacob, Belén Marrón, Jay Ehrlich, Peter A Rutherford
Pharmacovigilance is instrumental in helping to ensure patient safety for both newly released drugs and those that are well established in the market. However, while pharmacovigilance procedures are strictly regulated in the clinical trial setting, post-marketing adverse event reporting is not well implemented or enforced. As such, the underreporting of adverse events, in relation to drugs that are on the market, is estimated to be in the region of 90%. The identification of drug safety issues in patients with complex diseases and extensive comorbidities is therefore particularly challenging...
2013: Drug, Healthcare and Patient Safety
Jamal Al Wakeel, Ahmed H Mitwalli, Abdulkareem Alsuwaida, Mohammad Al Ghonaim, Saira Usama, Ashik Hayat, Iqbal Hamid Shah
INTRODUCTION: The month of Ramadan holds great religious and social significance for Muslims all over the world. The aim of the present study was to provide a modified dialysis schedule for peritoneal dialysis (PD) patients that allows for fasting and that minimizes the effect on the patient's general health and volume status. METHODS: We observed 31 patients under treatment at the PD unit of King Khalid University Hospital, King Saud University, Riyadh. During the 3 - 4 weeks before the start of Ramadan, all patients were counseled individually and in detail about the possibility of fasting...
January 2013: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Sung Ryol Lee, Hyung Ook Kim, Jun Ho Shin, Chang Hak Yoo
BACKGROUND/AIMS: Peritoneal carcinomatosis is the most common recurrence type in gastric cancer. Disseminated tumor cells derived from serosal invasion may be indicators of early peritoneal seeding and subsequent peritoneal dissemination. Reverse-transcriptase polymerase chain reaction (RT-PCR) techniques have been introduced to aid in detection of disseminated tumor cells in peritoneal washes, however, use of a single molecular marker lacks adequate sensitivity. We sought to improve both sensitivity and specificity in detecting disseminated tumor cells in peritoneal washes by using two markers; carcinoembryonic antigen (CEA) and cytokeratin 20 mRNA (CK20 mRNA)...
July 2013: Hepato-gastroenterology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"