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https://www.readbyqxmd.com/read/29333779/-decalcified-freeze-dried-bone-allograft-combined-with-rich-platelet-derivatives-for-the-treatment-of-human-periodontal-intrabony-defects-a-meta-analysis
#1
Wei Xue, Zhong Xiaobo, He Bin, Deng Yanhan, Luo Shumei
OBJECTIVE: This review aims to systematically evaluate the effect of decalcified freeze-dried bone allograft (DFDBA) combined with rich platelet derivatives on the treatment of human periodontal intrabony defects. METHODS: A search in PubMed, Web of Science, Embase, Cochrane Library, CNKI, and other electronic databases was conducted to identify randomized controlled trials (RCT) of the use of DFDBA combined with rich platelet derivatives in the treatment of human periodontal intrabony defects, performed before May 2016...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29333517/safety-and-feasibility-of-platelet-rich-fibrin-matrix-injections-for-treatment-of-common-urologic-conditions
#2
Ethan L Matz, Amy M Pearlman, Ryan P Terlecki
Purpose: Autologous platelet rich plasma (PRP) is used increasingly in a variety of settings. PRP injections have been used for decades to improve angiogenesis and wound healing. They have also been offered commercially in urology with little to no data on safety or efficacy. PRP could theoretically improve multiple urologic conditions, such as erectile dysfunction (ED), Peyronie's disease (PD), and stress urinary incontinence (SUI). A concern with PRP, however, is early washout, a situation potentially avoided by conversion to platelet rich fibrin matrix (PRFM)...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29332181/management-of-rotator-cuff-injuries-in-the-elite-athlete
#3
REVIEW
Leigh J Weiss, Dean Wang, Michael Hendel, Philip Buzzerio, Scott A Rodeo
PURPOSE OF REVIEW: Rotator cuff injuries are a common cause of pain and dysfunction for the elite athlete and can result in time loss from participation. This review highlights the current management of these injuries. RECENT FINDINGS: Conservative management of rotator cuff injuries continues to be the "gold standard" in the elite athlete. This includes a comprehensive rehabilitation program, anti-inflammatories, and corticosteroid injections. Newer treatment techniques such as intramuscular dry needling and the use of biologics such as platelet-rich plasma and stem cells demonstrate early promising results; however, these modalities require further investigation to determine their effectiveness...
January 13, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29326521/surgical-management-of-large-radicular-cyst-associated-with-mandibular-deciduous-molar-using-platelet-rich-fibrin-augmentation-a-rare-case-report
#4
Vijaya S Dhote, Nilima R Thosar, Sudhindra M Baliga, Priyanti Dharnadhikari, Poonam Bhatiya, Punit Fulzele
Radicular cysts arising from deciduous teeth are rare and usually cause a large bony defect. Autologous platelet-rich fibrin (PRF) is an easily available healing biomaterial in oral surgical defect with the new perspective of accelerated healing of a large bony defect. The present case is of unusually large radicular associated with neglected carious mandibular deciduous second molar in 10-year-old girl and its surgical management with PRF augmentation as a healing biomaterial in the bony defect. One-year follow-up showed uneventful healing and eruption of succedaneous tooth...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29326502/comparative-evaluation-of-platelet-rich-fibrin-with-connective-tissue-grafts-in-the-treatment-of-miller-s-class-i-gingival-recessions
#5
Sonam Mufti, Sarvagna Mayank Dadawala, Phoram Patel, Monali Shah, Deepak Harish Dave
Background: One of the most common aesthetic problem encountered in the field of periodontology is gingival recession, which is, perceived by the patients as increase in length of teeth. The treatment of buccal gingival recession is a common requirement due to aesthetic concern or root sensitivity. This study was planned to evaluate the efficacy of PRF membrane compared to that of CTG in Miller's class I gingival recessions. Materials and Methods: 32 sites with Miller's Class I gingival recessions, out of which 16 sites received PRF (test) and 16 sites received CTG (control)...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29324848/platelet-rich-plasma-to-treat-experimentally-induced-skin-wounds-in-animals-a-systematic-review-and-meta-analysis
#6
Adolfo Maria Tambella, Anna Rita Attili, Gilles Dupré, Andrea Cantalamessa, Stefano Martin, Vincenzo Cuteri, Sabrina Marcazzan, Massimo Del Fabbro
The objective of the study was to review current literature to determine whether the topical application of platelet-rich plasma (PRP) promotes healing in experimentally-induced full-thickness skin wounds in animals. The hypothesis was that the adjunct of PRP has a positive effect on wound healing. An electronic search was carried out on the following databases: Web of Science, Cochrane Library, PubMed, Research Gate, Cochrane Wounds Group, Veterinary Information Network. No publication date nor language restrictions were applied...
2018: PloS One
https://www.readbyqxmd.com/read/29320964/autologous-us-guided-prp-injection-versus-us-guided-focal-extracorporeal-shock-wave-therapy-for-chronic-lateral-epicondylitis-a-minimum-of-2-year-follow-up-retrospective-comparative-study
#7
Mattia Alessio-Mazzola, Ilaria Repetto, Besmir Biti, Roberto Trentini, Matteo Formica, Lamberto Felli
PURPOSE: To compare the efficacy of two independent groups of patients treated with ultrasound (US)-guided extracorporeal shock wave (ESW) therapy and with US-guided injection of platelet-rich plasma (PRP) for chronic lateral epicondylitis (LE) with a minimum of 2-year follow-up. METHODS: We retrospectively evaluated 63 patients treated for chronic LE (31 patients with autologous US-guided PRP injection and 32 patients with US-guided focal ESW therapy) from 2009 to 2014...
January 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29320421/comparative-analysis-of-different-platelet-lysates-and-platelet-rich-preparations-to-stimulate-tendon-cell-biology-an-in-vitro-study
#8
Franka Klatte-Schulz, Tanja Schmidt, Melanie Uckert, Sven Scheffler, Ulrich Kalus, Markus Rojewski, Hubert Schrezenmeier, Axel Pruss, Britt Wildemann
The poor healing potential of tendons is still a clinical problem, and the use of Platelet Rich Plasma (PRP) was hypothesized to stimulate healing. As the efficacy of PRPs remains unproven, platelet lysate (PL) could be an alternative with its main advantages of storage and characterization before use. Five different blood products were prepared from 16 male donors: human serum, two PRPs (Arthrex, (PRP-ACP); RegenLab (PRP-BCT)), platelet concentrate (apheresis, PC), and PL (freezing-thawing destruction of PC)...
January 10, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29316815/effect-of-l-prp-treatment-on-wound-healing-after-surgical-skin-incision-in-an-experimental-animal-model
#9
Agata Cieślik-Bielecka, Marcin Pierchała, Aleksandra Królikowska, Paweł Reichert
AIM OF THE STUDY: The aim of the study was to evaluate the effect of leukocyte- and platelet-rich plasma (L-PRP) treatment on a noncomplicated would healing after surgical skin incision in an experimental animal model. MATERIALS AND METHODS: The blood from 64 male Wistar rats was used to prepare L-PRP before a transverse dorsal incision was made and consecutively closed. At the same time after the surgery was completed, autologous L-PRP in the rats from the L-PRP group (n = 32) and NaCl in the control group (n = 32) were injected subcutaneously into the wound...
January 9, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29316445/does-intra-alveolar-application-of-chlorhexidine-gel-in-combination-with-platelet-rich-fibrin-have-an-advantage-over-application-of-platelet-rich-fibrin-in-decreasing-alveolar-osteitis-after-mandibular-third-molar-surgery-a-double-blinded-randomized-clinical
#10
Majid Eshghpour, Nasrin Danaeifar, Hamed Kermani, Amir Hossein Nejat
PURPOSE: To evaluate the effectiveness of chlorhexidine (CHX) gel and platelet-rich fibrin (PRF) compared with PRF alone in preventing the development of alveolar osteitis (AO). MATERIALS AND METHODS: In a double-blinded trial, patients undergoing surgical management of bilateral impacted mandibular third molars were randomly divided into 2 groups; 1 group received PRF in 1 extraction socket with the other socket as its control and the other group received 0.2% CHX gel plus PRF in 1 socket with the other socket serving as its control...
December 16, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29316152/clinical-and-immunohistochemical-comparative-study-of-the-efficacy-of-carboxytherapy-vs-platelet-rich-plasma-in-treatment-of-stretch-marks
#11
Abeer A Hodeib, Ghada F R Hassan, Marwa N M Ragab, Eiman A Hasby
BACKGROUND: Striae distensae are dermal scars with a linear atrophic depression. The exact origin of striae distensae remains unrevealed, but low expression of collagen and fibronectin genes in the affected tissue was found. Several treatment modalities have been proposed, yet no consistent modality is available. AIM OF THE WORK: To evaluate and compare the efficacy and safety of carboxytherapy vs platelet-rich plasma (PRP) in treatment of stretch marks. PATIENTS AND METHODS: This study included 20 patients with striae alba...
January 7, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29316139/stem-cell-therapy-in-refractory-perineal-crohn-s-disease-long-term-follow-up
#12
Claudio Wainstein, Rodrigo Quera, Daniela Fluxá, Udo Kronberg, Alejandro Conejero, Francisco López-Köstner, Claudio Jofre, Alejandro J Zarate
AIM: To describe the long-term outcomes of adipose-mesenchymal stem cells, platelet-rich plasma, and endorectal advancement flaps in patients with Perineal Crohn's Disease. METHOD: This was a single-center, prospective, observational pilot study performed between March 2013 and December 2016. The study included adult patients diagnosed with Perianal Crohn's Disease (with complex perianal fistulas) refractory to previous surgical and/or biological treatment. Patients underwent surgical treatment in two stages...
January 6, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29315284/should-autologous-platelet-rich-plasma-be-used-in-patients-with-hematologic-disease
#13
Arturo J Martí-Carvajal
No abstract text is available yet for this article.
December 2017: Clinical Advances in Hematology & Oncology: H&O
https://www.readbyqxmd.com/read/29314633/leucocyte-and-platelet-rich-fibrin-a-carrier-of-autologous-multipotent-cells-for-regenerative-medicine
#14
Rosa Di Liddo, Thomas Bertalot, Alessio Borean, Ivan Pirola, Alberto Argentoni, Sandra Schrenk, Carola Cenzi, Stefano Capelli, Maria Teresa Conconi, Pier Paolo Parnigotto
The wound healing is a complex process wherein inflammation, proliferation and regeneration evolve according to a spatio-temporal pattern from the activation of coagulation cascade to the formation of a plug clot including fibrin matrix, blood-borne cells and cytokines/growth factors. Creating environments conducive to tissue repair, the haemoderivatives are commonly proposed for the treatment of hard-to-heal wounds. Here, we explored in vitro the intrinsic regenerative potentialities of a leucocyte- and platelet-rich fibrin product, known as CPL-MB, defining the stemness grade of cells sprouting from the haemoderivative...
January 5, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29314065/platelet-rich-fibrin-combined-with-a-porous-hydroxyapatite-graft-for-the-treatment-of-3-wall-intrabony-defects-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#15
A R Pradeep, Pavan Bajaj, Nishanth S Rao, Esha Agarwal, Savitha B Naik
BACKGROUND: Porous hydroxyapatite (HA) bone grafting material has been used to fill periodontal intrabony defects (IBDs), resulting in clinically acceptable responses. Platelet-rich fibrin (PRF) is a leukocyte and platelet preparation that concentrates various polypeptide growth factors and, therefore, has the potential for use as regenerative treatment for periodontal defects. The present study aims to explore the clinical and radiographic effectiveness of autologous PRF versus PRF + HA in treatment of IBDs in patients with chronic periodontitis...
December 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/29313321/the-matrix-synthesis-and-anti-inflammatory-effect-of-autologous-leukocyte-poor-platelet-rich-plasma-in-human-cartilage-explants
#16
Mario Simental-Mendía, Félix Vilchez-Cavazos, Rubén García-Garza, Jorge Lara-Arias, Roberto Montes-de-Oca-Luna, Salvador Said-Fernández, Herminia G Martínez-Rodríguez
OBJECTIVE: To determine the effects of autologous leukocyte-poor platelet-rich plasma (LP-PRP) on the expression of markers involved in cartilage-extracellular matrix production and inflammation in cartilage explants bearing osteoarthritis. MATERIALS AND METHODS: Cartilage explants and LP-PRP were obtained from 10 patients who underwent total knee arthroplasty. The explants were cultured in spinner flasks for 28 days in the presence of interleukin (IL)-1β and/or LP-PRP...
January 9, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29306567/platelet-rich-plasma-derived-scaffolds-increase-the-benefit-of-delayed-mesenchymal-stromal-cell-therapy-after-severe-traumatic-brain-injury
#17
Celia Bonilla Horcajo, Mercedes Zurita Castillo, Jesús Vaquero Crespo
BACKGROUND: Cell therapy using mesenchymal stromal cells (MSCs) offers new perspectives in the treatment of traumatic brain injury (TBI). The aim of the present study was to assess the impact of platelet-rich plasma scaffolds (PRPS) as support of MSCs in a delayed phase after severe TBI in rats. METHODS: TBI was produced by weight-drop impact to the right cerebral hemisphere. Two months after TBI, four experimental groups were established; saline, PRPS, MSCs in saline, or MSCs in PRPS was transplanted into the area of brain lesion through a small hole...
January 3, 2018: Cytotherapy
https://www.readbyqxmd.com/read/29304975/editorial-commentary-don-t-pig-out-when-selecting-a-shoulder-rotator-cuff-augmentation-graft-xenografts-are-not-the-way-to-go
#18
EDITORIAL
F Alan Barber
Porcine xenograft dermal onlay augmentation of rotator cuff repair does not provide improved cuff integrity or provide better clinical outcomes. The retear rate was actually higher in repairs augmented with a porcine xenograft than the control group. Adverse events occurred in 60% of the xenograft patients compared with 40% of the controls. The use of liquid platelet-rich plasma had no discernible impact. A total of 85% of the observed failures with the suture-bridging double-row repair were at the medial cuff (Cho type 2)...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29304969/editorial-commentary-internet-resources-for-platelet-rich-plasma-an-electronic-repository-of-alternative-facts
#19
EDITORIAL
Peter D Fabricant
Information about platelet-rich plasma available on the Internet is of poor quality, low accuracy, and difficult to read. But we can do better. Before consultation or as part of the informed consent process, surgeons can direct patients to prescreened, commercial-free information published in a peer-reviewed manner by authoritative third-party specialty societies. By establishing the baseline level of knowledge before a deeper discussion about the individual patient's condition, surgeons can effectively engage with a better-informed patient and enjoy a more effective physician-patient encounter...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29304524/amino-fucoidan-as-a-vector-for-rtpa-induced-fibrinolysis-in-experimental-thrombotic-events
#20
Radouane Ghebouli, Stephane Loyau, Murielle Maire, Pierre Saboural, Jean-Philippe Collet, Martine Jandrot-Perrus, Didier Letourneur, Frédéric Chaubet, Jean-Baptiste Michel
Acute ischaemic stroke, myocardial infarction and pulmonary embolism are the main causes of mortality and morbidity worldwide. Thrombolysis by intravenous injection of recombinant tissue plasminogen activator (rtPA) remains the most common non-interventional treatment to recanalize occluded vessels. However, this procedure is limited by significant drawbacks, including high doses and bleeding complications. Recent studies showed that fucoidan targets the intraluminal thrombus in vivo. We have developed a chimaera covalently linking fucoidan, able to target platelets within the thrombus, to dilysine, able to non-covalently bind rtPA...
January 2018: Thrombosis and Haemostasis
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