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https://www.readbyqxmd.com/read/28934836/pregnancy-in-women-with-hypertrophic-cardiomyopathy-data-from-the-european-society-of-cardiology-initiated-registry-of-pregnancy-and-cardiac-disease-ropac
#1
S Goland, I M van Hagen, G Elbaz-Greener, U Elkayam, A Shotan, W M Merz, S C Enar, I R Gaisin, P G Pieper, M R Johnson, R Hall, A Blatt, J W Roos-Hesselink
Aims: We report the maternal and foetal outcomes at birth and after 6 months in a cohort of pregnant women with hypertrophic cardiomyopathy (HCM). Although most women with HCM tolerate pregnancy well, there is an increased risk of obstetric and cardiovascular complications. Methods and results: All pregnant women with HCM entered into the prospective worldwide Registry of Pregnancy and Cardiac disease (ROPAC) were included in this analysis. The primary endpoint was a major adverse cardiovascular event (MACE), which included death, heart failure (HF), thrombo-embolic event, and arrhythmia...
September 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28934822/stent-placement-for-benign-esophageal-leaks-perforations-and-fistulae-a-clinical-prediction-rule-for-successful-leakage-control
#2
Emo E van Halsema, Wouter F W Kappelle, Bas L A M Weusten, Robert Lindeboom, Mark I van Berge Henegouwen, Paul Fockens, Frank P Vleggaar, Manon C W Spaander, Jeanin E van Hooft
Background and study aims Sealing esophageal leaks by stent placement allows healing in 44 % - 94 % of patients. We aimed to develop a prediction rule to predict the chance of successful stent therapy. Patients and methods In this multicenter retrospective cohort study, patients with benign upper gastrointestinal leakage treated with stent placement were included. We used logistic regression analysis including four known clinical predictors of stent therapy outcome. The model performance to predict successful stent therapy was evaluated in an independent validation sample...
September 21, 2017: Endoscopy
https://www.readbyqxmd.com/read/28934808/competency-based-teaching-in-radiology-implementation-and-evaluation-of-interactive-workstation-based-learning-to-apply-nklm-based-content
#3
Wolfgang Koestner, Wiebke Otten, Till Kaireit, Frank K Wacker, Sabine Dettmer
Purpose New teaching formats are required to implement competency-based teaching in radiology teaching. Therefore, we have established and evaluated two practical competency-based radiological courses. Materials and Methods The courses were held in a multimedia room with 25 computers and a professional DICOM viewer. Students were taught basic image analysis and presented clinical cases with a DICOM viewer under supervision of an instructor using desktop monitoring software. Two courses (elective course and obligatory course) were evaluated by the students (n = 160 and n = 100) and instructors (n = 9) using an anonymized online survey...
September 21, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28934806/radiation-exposure-during-uterine-fibroid-embolization-ufe-a-confounder-controlled-comparison-between-a-state-of-the-art-angiography-unit-and-a-conventional-angiography-unit
#4
Christof-Matthias Sommer, Wieland Voigt, Michel Klapp Oliger, Christopher L Schlett, Stefan Erpenbach, Katrina Thomas, Andreas Hatopp, Patrick Kurz, Goetz M Richter
Purpose To compare radiation exposure of a state-of-the-art and a conventional angiography unit in patients undergoing uterine fibroid embolization (UFE). Materials and Methods Between January 2009 and December 2016, 286 patients underwent UFE in our Interdisciplinary Fibroid Center. The inclusion criteria for this retrospective analysis were first-time transarterial embolization for symptomatic fibroids, bilateral embolization, procedures applying a state-of-the-art (Group 1) or a conventional angiography unit (Group 2), and bilateral technical success with an adequate embolization endpoint after the injection of microspheres...
September 21, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28934801/increasing-rates-of-imaging-in-failed-back-surgery-syndrome-patients-implications-for-spinal-cord-stimulation
#5
S Harrison Farber, Jing L Han, Frank W Petraglia Iii, Robert Gramer, Siyun Yang, Promila Pagadala, Beth Parente, Jichun Xie, Jeffrey R Petrella, Shivanand P Lad
BACKGROUND: Failed back surgery syndrome (FBSS) has a high incidence following spinal surgery, is notoriously refractory to treatment, and results in high health care utilization. Spinal cord stimulation (SCS) is a well-accepted modality for pain relief in this population; however, until recently magnetic resonance imaging (MRI) was prohibited due to risk of heat conduction through the device. OBJECTIVES: We examined trends in imaging use over the past decade in patients with FBSS to determine its impact on health care utilization and implications for patients receiving SCS...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934799/factors-influencing-the-application-of-a-biopsychosocial-perspective-in-clinical-judgement-of-chronic-pain-interactive-management-with-medical-students
#6
Christopher P Dwyer, Phoebe E McKenna-Plumley, Hannah Durand, Emer M Gormley, Brian W Slattery, Owen M Harney, Padraig MacNeela, Brian E McGuire
BACKGROUND: Though there is wide support for the application of biopsychosocial perspectives in clinical judgement of chronic pain cases, such perspectives are often overlooked due to either inadequate training or attitudes favoring a biomedical approach. Recent research has indicated that despite such explanations, both established general practitioners (GP) and medical students account for some psychosocial factors when making clinical judgements regarding chronic pain cases, but report not being likely to apply these in real-world, clinical settings due to numerous factors, including available time with patients...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934725/prenatal-exposure-to-mercury-associations-with-global-dna-methylation-and-hydroxymethylation-in-cord-blood-and-in-childhood
#7
Andres Cardenas, Sheryl L Rifas-Shiman, Lode Godderis, Radu-Corneliu Duca, Ana Navas-Acien, Augusto A Litonjua, Dawn L DeMeo, Kasey J Brennan, Chitra J Amarasiriwardena, Marie-France Hivert, Matthew W Gillman, Emily Oken, Andrea A Baccarelli
BACKGROUND: Mercury is a global pollutant, and prenatal exposure is associated with adverse health effects. To date, no studies have evaluated the association between prenatal mercury exposure and DNA hydroxymethylation, an epigenetic modification important for tissue differentiation and embryonic development. OBJECTIVES: We sought to evaluate the association between prenatal mercury exposure and offspring global DNA methylation and hydroxymethylation at birth and test for persistence of the association in childhood...
August 29, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934721/association-of-long-term-exposure-to-transportation-noise-and-traffic-related-air-pollution-with-the-incidence-of-diabetes-a-prospective-cohort-study
#8
Charlotte Clark, Hind Sbihi, Lillian Tamburic, Michael Brauer, Lawrence D Frank, Hugh W Davies
BACKGROUND: Evidence for an association between transportation noise and cardiovascular disease has increased; however, few studies have examined metabolic outcomes such as diabetes or accounted for environmental coexposures such as air pollution, greenness, or walkability. OBJECTIVES: Because diabetes prevalence is increasing and may be on the causal pathway between noise and cardiovascular disease, we examined the influence of long-term residential transportation noise exposure and traffic-related air pollution on the incidence of diabetes using a population-based cohort in British Columbia, Canada...
August 31, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934713/imposex-levels-and-butyltin-compounds-bts-in-hexaplex-trunculus-linnaeus-1758-from-the-northern-adriatic-sea-italy-ecological-risk-assessment-before-and-after-the-ban
#9
Federica Cacciatore, Rossella Boscolo Brusà, Seta Noventa, Camilla Antonini, Vanessa Moschino, Malgorzata Formalewicz, Claudia Gion, Daniela Berto, Massimo Gabellini, Maria Gabriella Marin
The aim of this study was to compare imposex and butyltin compounds (BTs) data, collected before and after the organotin ban in 2008, in order to assess temporal and spatial variation of the phenomenon, the decline of BT contamination, and the effects on Hexaplex trunculus population in the coastal area of the northern Adriatic Sea, close to the Venice Lagoon. Both in marine and in lagoon sites, the results obtained in 2013-2015 showed a significant decline in the incidence of imposex in respect to those from the 2002 survey...
September 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28934711/alterations-of-larval-photo-dependent-swimming-responses-pdr-new-endpoints-for-rapid-and-diagnostic-screening-of-aquatic-contamination
#10
Luis Colón-Cruz, Lauren Kristofco, Jonathan Crooke-Rosado, Agnes Acevedo, Aranza Torrado, Bryan W Brooks, María A Sosa, Martine Behra
Detection and toxicity assessment of waterborne contaminants are crucial for protecting human health and the environment. Development of easy-to-implement, rapid and cost-effective tools to measure anthropogenic effects on watersheds are critical for responsible management, particularly in times of increasing development and urbanization. Traditionally, environmental toxicology has focused on limited endpoints, such as lethality and fertility, which are directly affecting population levels. However, more sensitive readings are needed to assess sub-lethal effects...
September 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28934684/scientific-evidence-for-the-identification-of-an-aboriginal-massacre-at-the-sturt-creek-sites-on-the-kimberley-frontier-of-north-western-australia
#11
Pamela A Smith, Mark D Raven, Keryn Walshe, Robert W Fitzpatrick, F Donald Pate
Archival research into episodes of frontier violence in the Kimberley region of Western Australia indicate that the bodies of Aboriginal victims of massacres were frequently incinerated following the event. This paper presents the results of a scientific investigation of a reported massacre at Sturt Creek where burnt bone fragments were identified in two adjacent sites and documents the archaeological signatures associated with the sites. The methodology used to undertake the project brought together three systems of knowledge: the oral testimonies of the descent group originating from a sole adult survivor of the massacre; archival, historical and scientific research...
August 31, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28934657/characterisation-of-artisanal-mine-waste-on-buru-island-indonesia-and-toxicity-to-the-brittle-star-amphipholis-squamata
#12
Amanda J Reichelt-Brushett, Bernard Thomas, Pelli L Howe, Yusthinus Male, Malcolm W Clark
Artisanal small-scale gold mining (ASGM) using mercury (Hg) amalgamation commenced on Buru Island, Indonesia, in 2012, but was halted in 2015 due to concerns of widespread Hg contamination. Much of the Hg used in the mining process is lost to trommel waste which is disposed of in settlement ponds that drain into adjacent waterways and into Kayeli Bay. Several thousand unmanaged trommel sites and associated tailing ponds exist on Buru Island. This study shows that waste from the Marloso trommel at the Gogrea site contained 203 mg/kg total Hg (THg), with a negligible proportion present as bioavailable methyl Hg (MeHg) and a low total organic carbon content...
September 12, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934650/influence-of-human-activities-and-organic-matters-on-occurrence-of-polybrominated-diphenyl-ethers-in-marine-sediment-core-a-case-study-in-the-southern-yellow-sea-china
#13
Guoguang Wang, Lijuan Feng, Jingshuai Qi, Xianguo Li
The Southern Yellow Sea (SYS) is an important reservoir of anthropogenic organic contaminants, such as polybrominated diphenyl ethers (PBDEs). To reconstruct the historical records of PBDEs and examine their relationships with the human activities and organic matters, a(210)Pb-dated sediment core was collected from the central mud area in the SYS. The concentrations of tri-to hepta-BDEs (∑7PBDEs) and BDE-209 ranged from 9.8 to 99.8 pg g(-1) d.w. and from 12.1 to 855.4 pg g(-1) d.w., respectively, both displaying the increasing trends from the bottom to the surface...
September 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934649/cooperative-stimulation-of-atherogenesis-by-lipopolysaccharide-and%C3%A2-palmitic-acid-rich-high-fat-diet-in-low-density-lipoprotein-receptor-deficient-mice
#14
Zhongyang Lu, Yanchun Li, Colleen W Brinson, Maria F Lopes-Virella, Yan Huang
BACKGROUND AND AIMS: Either lipopolysaccharide (LPS) or high-fat diet (HFD) enriched with saturated fatty acid (SFA) promotes atherosclerosis. In this study, we investigated the effect of LPS in combination with SFA-rich HFD on atherosclerosis and how LPS and SFA interact to stimulate inflammatory response in vascular endothelial cells. METHODS: Low-density lipoprotein receptor-deficient (LDLR(-/-)) mice were fed a low-fat diet (LFD), HFD with low palmitic acid (PA) (LP-HFD), or HFD with high PA (HP-HFD) for 20 weeks...
September 9, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28934549/selective-electrodeposition-of-tantalum-v-oxide-electrodes
#15
Hamed Hajibabaei, Thomas W Hamann
Thin films of TaOxHy were cathodically electrodeposited from an aqueous solution containing Ta-IPA precursor and KNO3 as a sacrificial agent. It was shown that the deposition resulted from a precipitation reaction triggered by the local change of pH at the surface of working electrode. Combined structural and compositional analysis revealed that during the electrodeposition the oxidation state of tantalum remained constant, Ta(V). The as-deposited films are mesoporous amorphous tantalum oxide hydrate films, which can be converted to either pure Ta2O5 or Ta3N5 by high-temperature annealing in either air (or Ar) or ammonia, respectively...
September 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28934540/safe-positioning-for-sexual-intercourse-after-proximal-femoral-replacement
#16
Cory G Couch, Richard W Nicholas, Corey O Montgomery
Hip arthroplasty is a common procedure used for the treatment of fractures and degenerative processes affecting the hip. Proximal femoral replacement is an uncommon type of hip arthroplasty used for reconstruction after extensive bone loss. Proximal femoral replacement is used most commonly after the resection of the proximal femur for malignancies and for extensive bone loss encountered in revision hip arthroplasty and occasionally for extensive bone loss after fractures. The authors present a case of a female patient who sustained a prosthetic dislocation of her proximal femoral replacement during sexual intercourse...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28934531/feasibility-and-emotional-impact-of-experimentally-extending-sleep-in-short-sleeping-adolescents
#17
Tori R Van Dyk, Nanhua Zhang, Perry A Catlin, Kaylin Cornist, Shealan McAlister, Catharine Whitacre, Dean W Beebe
Study Objectives: Published experimental sleep manipulation protocols for adolescents have been limited to the summer, limiting causal conclusions about how short sleep affects them on school nights, when they are most likely to restrict their sleep. This study assesses the feasibility and emotional impact of a school-night sleep manipulation protocol to test the effects of lengthening sleep in habitually short-sleeping adolescents. Methods: High school students aged 14-18 years who habitually slept 5-7 hours on school nights participated in a 5-week experimental sleep manipulation protocol...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934523/sleep-stage-transition-dynamics-reveal-specific-stage-2-vulnerability-in-insomnia
#18
Yishul Wei, Michele A Colombo, Jennifer R Ramautar, Tessa F Blanken, Ysbrand D van der Werf, Kai Spiegelhalder, Bernd Feige, Dieter Riemann, Eus J W Van Someren
Study Objectives: Objective sleep impairments in insomnia disorder (ID) are insufficiently understood. The present study evaluated whether whole-night sleep stage dynamics derived from polysomnography (PSG) differ between people with ID and matched controls and whether sleep stage dynamic features discriminate them better than conventional sleep parameters. Methods: Eighty-eight participants aged 21-70 years, including 46 with ID and 42 age- and sex-matched controls without sleep complaints, were recruited through www...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934522/effects-of-cannabinoid-agonists-and-antagonists-on-sleep-and-breathing-in-sprague-dawley-rats
#19
Michael W Calik, David W Carley
Study Objectives: There are no pharmacological treatments for obstructive sleep apnea syndrome, but dronabinol showed promise in a small pilot study. In anesthetized rats, dronabinol attenuates reflex apnea via activation of cannabinoid (CB) receptors located on vagal afferents; an effect blocked by cannabinoid type 1 (CB1) and/or type 2 (CB2) receptor antagonists. Here, using a natural model of central sleep apnea, we examine the effects of dronabinol, alone and in combination with selective antagonists in conscious rats chronically instrumented to stage sleep and measure cessation of breathing...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934512/increased-patient-satisfaction-and-a-reduction-in-pre-analytical-errors-following-implementation-of-an-electronic-specimen-collection-module-in-outpatient-phlebotomy
#20
Michalis Kantartjis, Stacy E F Melanson, Athena K Petrides, Adam B Landman, David W Bates, Bernard A Rosner, Ellen Goonan, Ida Bixho, Milenko J Tanasijevic
Background: Patient satisfaction in outpatient phlebotomy settings typically depends on wait time and venipuncture experience, and many patients equate their experiences with their overall satisfaction with the hospital. Methods: We compared patient service times and preanalytical errors pre- and postimplementation of an integrated electronic health record (EHR)-laboratory information system (LIS) and electronic specimen collection module. We also measured patient wait time and assessed patient satisfaction using a 5-question survey...
August 1, 2017: Laboratory Medicine
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