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Aura Ruiz, Daniel Cuestas, Paula Garcıa, Jose Quintero, Yency Forero, Ingrid Galvis, Oscar Velasquez
Burn management options are controversial and a multiple-handled issue. However, platelet-rich plasma is gaining interest in several medical fields. Dermatologist worldwide are already publishing some reports about its benefits and personal experiences in their practices. A 40-year-old female with a second-degree burn by VASER-type liposculpture was treated with platelet-rich plasma and followed up for 10 months. After treatment, she showed rapid improvement with an adequate cicatrization results. Some studies suggest that the use of platelet-rich plasma which contains cytokines and growth factors that participate in cellular repair and cellular differentiation, thus improving healing time and re-epithelization...
April 22, 2018: Journal of Cosmetic Dermatology
Dominik Duscher, Zeshaan N Maan, Anna Luan, Matthias M Aitzetmüller, Elizabeth A Brett, David Atashroo, Alexander J Whittam, Michael S Hu, Graham G Walmsley, Khosrow S Houschyar, Arndt F Schilling, Hans-Guenther Machens, Geoffrey C Gurtner, Michael T Longaker, Derrick C Wan
BACKGROUND AIMS: Regenerative medicine employs human mesenchymal stromal cells (MSCs) for their multi-lineage plasticity and their pro-regenerative cytokine secretome. Adipose-derived mesenchymal stromal cells (ASCs) are concentrated in fat tissue, and the ease of harvest via liposuction makes them a particularly interesting cell source. However, there are various liposuction methods, and few have been assessed regarding their impact on ASC functionality. Here we study the impact of the two most popular ultrasound-assisted liposuction (UAL) devices currently in clinical use, VASER (Solta Medical) and Lysonix 3000 (Mentor) on ASCs...
December 2017: Cytotherapy
Javier Vera Cucchiaro, Horacio Lostia, Patricia Velazquez, Elizabeth Liska
BACKGROUND: Proactively preserving Scarpa's fascia and thus its intrinsic lymphatic drainage and tensile strength for suture placement can eliminate the need for drains after lipoabdominoplasty and therefore reduce the rate of seroma development. In this article, we describe the effectiveness of a modified progressive traction suture (PTS) technique, which enables us to lessen the most common complications and avoid hospital readmission; these sutures take 3-5 minutes of additional surgery time...
June 2017: Plastic and Reconstructive Surgery. Global Open
Yoong Hoon Shim, Ru Hong Zhang
OBJECTIVE: Investigation and evaluation of the current methods and steps of autologous fat transplantation to optimize the viability of fat grafts and procedure outcome in quest of a more standardized protocol. METHODS: A thorough literature search was performed across the CNKI, Wan Fang, PubMed, Ovid and EMBASE databases from the year 1970 to December 2014, collecting and classifying all of the autologous fat transplantation-related reports and articles, and after screening, a critical retrospective analysis was performed on the included data...
August 2017: Aesthetic Plastic Surgery
Robert Vaser, Ivan Sović, Niranjan Nagarajan, Mile Šikić
The assembly of long reads from Pacific Biosciences and Oxford Nanopore Technologies typically requires resource-intensive error-correction and consensus-generation steps to obtain high-quality assemblies. We show that the error-correction step can be omitted and that high-quality consensus sequences can be generated efficiently with a SIMD-accelerated, partial-order alignment-based, stand-alone consensus module called Racon. Based on tests with PacBio and Oxford Nanopore data sets, we show that Racon coupled with miniasm enables consensus genomes with similar or better quality than state-of-the-art methods while being an order of magnitude faster...
May 2017: Genome Research
Alan F Merry, Jacqueline A Hannam, Craig S Webster, Kylie-Ellen Edwards, Jane Torrie, Chris Frampton, Daniel W Wheeler, Arun K Gupta, Ravi P Mahajan, Rachel Evley, Jennifer M Weller
BACKGROUND: Simulation has been used to investigate clinical questions in anesthesia, surgery, and related disciplines, but there are few data demonstrating that results apply to clinical settings. We asked "would results of a simulation-based study justify the same principal conclusions as those of a larger clinical study?" METHODS: We compared results from a randomized controlled trial in a simulated environment involving 80 cases at three centers with those from a randomized controlled trial in a clinical environment involving 1,075 cases...
March 2017: Anesthesiology
Magdalena Gibas-Dorna, Monika Szulińska, Piotr Turkowski, Justyna Kupsz, Anna Sowińska, Kinga Mikrut, Małgorzata Bernatek, Jacek Piatek
The aim of the current study was to examine the liposuction-induced metabolic changes with regard to release of major adipokines and insulin sensitivity in overweight male patients. Seventeen overweight male patients aged 37.15 ± 9.60 years (6 with diabetes type 2, 11 without comorbidities) and 10 age-matched healthy lean controls were enrolled in the study. Using Vibration Amplification of Sound Energy at Resonance System, ultrasound assisted liposuction was applied onto the deep layers of abdominal subcutaneous adipose tissue...
March 2017: American Journal of Men's Health
Robert Vaser, Dario Pavlović, Mile Šikić
MOTIVATION: Protein database search is one of the fundamental problems in bioinformatics. For decades, it has been explored and solved using different exact and heuristic approaches. However, exponential growth of data in recent years has brought significant challenges in improving already existing algorithms. BLAST has been the most successful tool for protein database search, but is also becoming a bottleneck in many applications. Due to that, many different approaches have been developed to complement or replace it...
September 1, 2016: Bioinformatics
Robert Vaser, Swarnaseetha Adusumalli, Sim Ngak Leng, Mile Sikic, Pauline C Ng
The SIFT (sorting intolerant from tolerant) algorithm helps bridge the gap between mutations and phenotypic variations by predicting whether an amino acid substitution is deleterious. SIFT has been used in disease, mutation and genetic studies, and a protocol for its use has been previously published with Nature Protocols. This updated protocol describes SIFT 4G (SIFT for genomes), which is a faster version of SIFT that enables practical computations on reference genomes. Users can get predictions for single-nucleotide variants from their organism of interest using the SIFT 4G annotator with SIFT 4G's precomputed databases...
January 2016: Nature Protocols
Mark E Schafer, Kevin C Hicok, Daniel C Mills, Steve R Cohen, James J Chao
BACKGROUND: Although clinical evidence of successful autologous fat transfer (AFT) using third-generation ultrasound-assisted liposuction (UAL) is readily available, no study has quantified adipocyte viability using standardized methods. OBJECTIVES: The authors assess acute adipocyte viability following fat aspiration as a first step in determining the overall efficacy of using third-generation UAL for AFT. METHODS: Lipoaspirate samples were collected from patients who underwent elective liposuction procedures at multiple surgery centers...
July 2013: Aesthetic Surgery Journal
Alan Matarasso
No abstract text is available yet for this article.
April 2012: Plastic and Reconstructive Surgery
Michael W Nagy, Paul F Vanek
BACKGROUND: No scientific comparative study has demonstrated any statistically significant clinical improvement attributable to a new lipoplasty technology relative to traditional suction-assisted lipoplasty. This prospective study used a contralateral study design to evaluate postoperative differences between vibration amplification of sound energy at resonance (VASER)-assisted lipoplasty and suction-assisted lipoplasty. METHODS: Twenty female patients between the ages of 20 and 48 years received contralateral treatment with suction-assisted lipoplasty and VASER-assisted lipoplasty in one or more anatomical regions for a total of 33 regions...
April 2012: Plastic and Reconstructive Surgery
Alfredo E Hoyos, John A Millard
BACKGROUND: The introduction of VASER (vibration amplification of sound energy at resonance) technology has enabled the application of lipoplasty techniques to the superficial fat layers. Differential lipoplasty has been used to detail abdominal musculature by "abdominal etching," but was applicable only to limited areas in male patients with low body fat. OBJECTIVE: The authors report on the use of VASER-assisted high-definition liposculpture to not only improve body contour but also to highlight the 3-dimensional muscular anatomy in a wide variety of patients...
November 2007: Aesthetic Surgery Journal
Mark Laurence Jewell, Peter Bela Fodor, Ewaldo Bolivar de Souza Pinto, Mussab Abdulrahman Al Shammari
BACKGROUND: Although lipoplasty is the most frequently performed aesthetic surgical procedure, ultrasound-assisted lipoplasty (UAL) has not been widely adopted because of its increased potential for complications, complex and bulky instrumentation, additional cost, and steep learning curve. OBJECTIVE: We report on the use of the VASER ultrasound device in lipoplasty procedures and compare the clinical outcomes obtained by means of VASER-assisted lipoplasty with those of other UAL devices...
March 2002: Aesthetic Surgery Journal
George W Commons, Angeline F Lim
BACKGROUND: Current methods of treatment for axillary hyperhidrosis and/or bromidrosis are palliative (use of topical aluminum chloride or injections of botulinum toxin type A) or surgically based for more permanence (excisional surgery, endoscopic transthoracic sympathectomy, liposuction/curettage). The surgical approaches have mixed effectiveness and incur the risk of significant side effects and complications. METHODS: Thirteen patients (3 males, 10 females) with significant axillary hyperhidrosis and/or bromidrosis were recruited, treated with the VASER ultrasound, and followed for 6 months...
May 2009: Aesthetic Plastic Surgery
Onelio Garcia, Nirmal Nathan
BACKGROUND: Lipoplasty remains the most common cosmetic surgical procedure performed in the United States. In spite of its well documented clinical advantages, ultrasound-assisted lipoplasty (UAL) accounts for less than 20% of all lipoplasty procedures currently performed. OBJECTIVE: The purpose of this study is to determine the blood content of third-generation internal UAL aspirate and compare it to traditional lipoplasty aspirate. METHODS: The lipoplasty aspirate of 27 consecutive patients who underwent traditional suction-assisted lipoplasty (SAL) of their back and posterior flanks was compared to the aspirate of 30 consecutive patients who underwent third-generation internal UAL of their backs and posterior flanks using the VASER Internal Ultrasound Device (Sound Surgical Technologies; Louisville, CO)...
July 2008: Aesthetic Surgery Journal
Ewaldo Bolivar de Souza Pinto, Priscila Chiarello de Souza Pinto Abdala, Christovam Montecinos Maciel, Fabiana de Paula Turchiari dos Santos, Rodrigo Pessoa Martello de Souza
VASER is a fat pretreatment device based on the emission of pulsed or continuous ultrasound energy to emulsify fat before its aspiration by means of suction-assisted lipoplasty or power-assisted lipoplasty. If compared with previous generation UAL machines, it carries important technologic advances that focus on the safety and efficiency of the process. VASER is the result of improvements in surgical instrumentation and technique, proper use of wetting solutions, and knowledge about the best use of ultrasound for fat fragmentation...
January 2006: Clinics in Plastic Surgery
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