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Silvia S Kang, Aishe Kurti, Damien A Fair, John D Fryer
Obesity induces a low-grade inflammatory state and has been associated with behavioral and cognitive alterations. Importantly, maternal environmental insults can adversely impact subsequent offspring behavior and have been linked with neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (AHDH). It is unknown if maternal obesity significantly alters offspring sociability, a key ASD feature, and if altering maternal diet will provide an efficacious intervention paradigm for behavioral deficits...
2014: Journal of Neuroinflammation
N Raman, A B Janse van Rensburg
OBJECTIVE: National and international child and adolescent mental healthcare policy and action advocate that the health and well being of children should be increasingly given greater attention. The purpose of this study was to describe the demographic, socio economic and clinical profile of the users at the child and adolescent mental health clinic of the Rahima Moosa Mother and Child Hospital (RMMCH). METHOD: A descriptive, retrospective clinical audit from users' clinical files was performed over a one-year period from January to December 2007...
September 2013: African Journal of Psychiatry
Shaun Goh Kok Yew, Richard O'Kearney
BACKGROUND: Prospective evidence on psychological outcomes for children with specific language impairments (SLI) is accumulating. To date, there has been no attempt to summarise what this evidence says about the strength of link between SLI and later child and adolescent emotional and behavioural (EB) outcomes. METHODS: We undertook a systematic review and meta-analysis (following PRISMA guidelines and involving a literature search to June 2012 of seven databases, including MEDLINE and PsychAPA) of prospective, cohort studies of children with SLI and typical language development (TLD) reporting on the incidence and severity of EB problems later in childhood or adolescence...
May 2013: Journal of Child Psychology and Psychiatry, and Allied Disciplines
Ridha Joober, Natalie Grizenko, Sarojini Sengupta, Leila Ben Amor, Norbert Schmitz, George Schwartz, Sherif Karama, Philippe Lageix, Ferid Fathalli, Adam Torkaman-Zehi, Marina Ter Stepanian
We sought to test the hypothesis that the variable number of tandem repeat (VNTR) polymorphism in the 3'-untranslated region (3'-UTR) of the SLC6A3 gene modulates behavior in children with ADHD and/or behavioral response to methylphenidate (MPH). One hundred and fifty-nine children with AHDH (6-12 years) were assessed with regard to the Conners' Global Index for parents (CGI-Parents) and teachers (CGI-Teachers) and the response of these behaviors to MPH (0.5 mg/kg/day) using a 2-week prospective within-subject (crossover) trial...
June 2007: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
Chung-Yao Chen, Chia-Ling Chen, Ching-Yi Wu, Hsieh-Ching Chen, Fuk-Tan Tang, May-Kuen Wong
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) was characterized by deficit in the attention mechanism. Until now, the visual-spatial attention deficit in children with ADHD remains controversial. We report a study of the visual spatial attention to assess covert shifts of attention and sustained attention theoretically linked to two neuroanatomically defined attentional system in the posterior and anterior parts of the human brain. METHODS: Using the Neuroscan system, the reaction time (RT) was measured according to three different within-subject conditions including cueing (valid, invalid and neutral); delay (800 msec and 100 msec); side [right visual field (RVF) and left visual field (LVF)] as well as one between-subject condition (healthy, ADHD)...
August 2002: Chang Gung Medical Journal
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