keyword
MENU ▼
Read by QxMD icon Read
search

Oral Motor

keyword
https://www.readbyqxmd.com/read/29129487/-evaluation-of-dysphagia-results-after-one-year-of-incorporating-videofluoroscopy-into-its-study-introduction
#1
Ruth García Romero, Ignacio Ros Arnal, María José Romea Montañés, José Antonio López Calahorra, Cristina Gutiérrez Alonso, Beatriz Izquierdo Hernández, Carlos Martín de Vicente
INTRODUCTION: Dysphagia is very common in children with neurological disabilities. These patients usually suffer from respiratory and nutritional problems. The videofluoroscopic swallowing study (VFSS) is the most recommended test to evaluate dysphagia, as it shows the real situation during swallowing. OBJECTIVES: To analyse the results obtained in our centre after one year of the implementation of VFSS, the clinical improvement after confirmation, and the prescription of an individualised treatment for the patients affected...
November 9, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29115586/characterization-of-kif11-as-a-novel-prognostic-biomarker-and-therapeutic-target-for-oral-cancer
#2
Kayo Daigo, Atsushi Takano, Phung Manh Thang, Yoshihiro Yoshitake, Masanori Shinohara, Iwau Tohnai, Yoshinori Murakami, Jiro Maegawa, Yataro Daigo
Oral cancer has a high mortality rate, and its incidence is increasing gradually worldwide. As the effectiveness of standard treatments is still limited, the development of new therapeutic strategies is eagerly awaited. Kinesin family member 11 (KIF11) is a motor protein required for establishing a bipolar spindle in cell division. The role of KIF11 in oral cancer is unclear. Therefore, the present study aimed to assess the role of KIF11 in oral cancer and evaluate its role as a prognostic biomarker and therapeutic target for treating oral cancer...
October 31, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/29114767/age-related-variability-in-tongue-pressure-patterns-for-maximum-isometric-and-saliva-swallowing-tasks
#3
Melanie Peladeau-Pigeon, Catriona M Steele
Purpose: The ability to generate tongue pressure plays a major role in bolus transport in swallowing. In studies of motor control, stability or variability of movement is a feature that changes with age, disease, task complexity, and perturbation. In this study, we explored whether age and tongue strength influence the stability of the tongue pressure generation pattern during isometric and swallowing tasks in healthy volunteers. Method: Tongue pressure data, collected using the Iowa Oral Performance Instrument, were analyzed from 84 participants in sex-balanced and decade age-group strata...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29106869/check-list-for-the-assessment-of-functional-impairment-in-children-with-congenital-aural-atresia
#4
Silvia Montino, Anna Agostinelli, Patrizia Trevisi, Alessandro Martini, Sara Ghiselli
OBJECTIVES: Congenital Aural Atresia (CAA) is a deformity of the external ear and it is commonly associated with malformations of middle and inner ear and, in some cases, with other facial deformities. Very few assessment measures exist for evaluating the functional impairment in children with CAA. Purpose of this study is to introduce and describe an assessment Checklist, (nominated FOS Checklist) that covers feeding abilities (F), oralmotor skills (O), communication/language development (S) in children with CAA...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29105865/oral-medication-prescription-practices-of-tertiary-based-specialists-for-dystonia-in-children-with-cerebral-palsy
#5
Adrienne Harvey, Dinah Reddihough, Adam Scheinberg, Katrina Williams
AIM: To examine current clinical practice for prescribing medications for children with dystonic cerebral palsy (CP) by medical doctors working at a tertiary care centre. METHODS: Rehabilitation and developmental paediatric specialists completed: (i) a custom-designed online cross-sectional survey capturing their usual prescribing patterns; and (ii) one-page questionnaires detailing medication prescription for each child with CP who they started on a new medication for dystonia over a 12-month period...
November 6, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29101668/gut-microbiota-are-disease-modifying-factors-after-traumatic-spinal-cord-injury
#6
REVIEW
Kristina A Kigerl, Klauss Mostacada, Phillip G Popovich
Spinal cord injury (SCI) disrupts the autonomic nervous system (ANS), impairing its ability to coordinate organ function throughout the body. Emerging data indicate that the systemic pathology that manifests from ANS dysfunction exacerbates intraspinal pathology and neurological impairment. Precisely how this happens is unknown, although new data, in both humans and in rodent models, implicate changes in the composition of bacteria in the gut (i.e., the gut microbiota) as disease-modifying factors that are capable of affecting systemic physiology and pathophysiology...
November 3, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29100951/distinct-cerebellar-regions-related-to-motor-and-cognitive-performance-in-sca6-patients
#7
Zubir Rentiya, Noore-Sabah Khan, Ezgi Ergun, Sarah H Ying, John E Desmond
OBJECTIVE: To demonstrate a correlation between anatomic regional changes in Spinocerebellar Ataxia type 6 (SCA6) patients and measures of cognitive performance on neuropsychological tests. METHODS: Neurocognitive testing was conducted on 24 SCA6 and 28 control subjects. For each cognitive test, SCA6 patients were compared against the controls using Student's t-test. For the cerebellar patients, using voxel based morphometry, correlations between cerebellar gray matter volume at each voxel and performance on the neuropsychological exams were calculated using the Pearson correlation coefficient implemented in SPM8...
October 31, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29099404/differential-effects-of-dopaminergic-drugs-on-spontaneous-motor-activity-in-the-common-marmoset-following-pretreatment-with-a-bilateral-brain-infusion-of-6-hydroxydopamine
#8
Kiyoshi Ando, Chiyoko Nishime, Ryo Inoue, Eiko Nishinaka, Kenji Kawai, Koji Urano, Hideki Tsutsumi
The differential effects of dopaminergic drugs with different pharmacological profiles were investigated with respect to spontaneous motor activity in the common marmoset following pretreatment with a bilateral brain infusion of 6-hydroxydopamine (6-OHDA). Three marmosets received infusions of 6-OHDA (either 30 or 40 μg/side) into the bilateral dopamine-rich area running from the substantia nigra to the striatum. The motor activity of the 6-OHDA marmosets was compared with that of three intact marmosets...
December 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/29094055/effect-of-menstrual-cycle-on-acute-intermittent-porphyria
#9
V R Souza Júnior, V M V Lemos, I M L Feitosa, R Florencio, C W B Correia, L B Correia Fontes, M F Hazin Costa, M C B Correia
A 16-year-old female who was attended as an outpatient reported localized, acute abdominal pain with vomiting, symmetrical motor weakness, and burning sensation in both arms and legs. Her medical history showed irrational behavior, repeated admissions at the emergency units of many other reference hospitals, where she had been investigated for celiac disease and treated with analgesics for pain events. Her clinical condition remained unchanged despite the use of many oral analgesics. In those admissions, she showed dysautonomia, vomiting, and abdominal pain...
January 2017: Child neurology open
https://www.readbyqxmd.com/read/29091783/neurodevelopmental-outcome-in-prenatally-diagnosed-isolated-agenesis-of-the-corpus-callosum
#10
Lise Folliot-Le Doussal, Alexandra Chadie, Marie Brasseur-Daudruy, Eric Verspyck, Pascale Saugier-Veber, Stéphane Marret
Neurodevelopmental outcome in children with agenesis of the corpus callosum (ACC) is correlated with the presence or absence of associated brain abnormalities. Indeed, neurodevelopmental outcome shows severe disabilities when the ACC is not isolated whereas in isolated forms, the neurologic development is mainly normal. Contrary to data in several published studies, the prognosis remains uncertain even in isolated forms, which may lead in France to medical termination of pregnancy. OBJECTIVE: To evaluate long-term neurodevelopmental outcome in children with prenatally diagnosed isolated ACC...
October 29, 2017: Early Human Development
https://www.readbyqxmd.com/read/29091740/comparison-between-pre-exercise-casein-peptide-and-intact-casein-supplementation-on-glucose-tolerance-in-high-fat-diet-fed-mice
#11
Yutaka Matsunaga, Yuki Tamura, Yasuyuki Sakata, Yudai Nonaka, Noriko Saito, Hirohiko Nakamura, Takashi Shimizu, Yasuhiro Takeda, Shin Terada, Hideo Hatta
We hypothesized that along with exercise, casein peptide supplementation would have a higher impact on improving glucose tolerance than intact casein. Male six-week-old ICR mice were provided a high-fat diet to induce obesity and glucose intolerance. The mice were randomly divided into four treatment groups: control (Con), endurance training (Tr), endurance training with intact casein supplementation (Cas+Tr), and endurance training with casein peptide supplementation (CP+Tr). The mice in each group were orally administrated water, intact casein, or casein peptide (1...
November 1, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29091557/single-dose-gene-replacement-therapy-for-spinal-muscular-atrophy
#12
Jerry R Mendell, Samiah Al-Zaidy, Richard Shell, W Dave Arnold, Louise R Rodino-Klapac, Thomas W Prior, Linda Lowes, Lindsay Alfano, Katherine Berry, Kathleen Church, John T Kissel, Sukumar Nagendran, James L'Italien, Douglas M Sproule, Courtney Wells, Jessica A Cardenas, Marjet D Heitzer, Allan Kaspar, Sarah Corcoran, Lyndsey Braun, Shibi Likhite, Carlos Miranda, Kathrin Meyer, K D Foust, Arthur H M Burghes, Brian K Kaspar
BACKGROUND: Spinal muscular atrophy type 1 (SMA1) is a progressive, monogenic motor neuron disease with an onset during infancy that results in failure to achieve motor milestones and in death or the need for mechanical ventilation by 2 years of age. We studied functional replacement of the mutated gene encoding survival motor neuron 1 (SMN1) in this disease. METHODS: Fifteen patients with SMA1 received a single dose of intravenous adeno-associated virus serotype 9 carrying SMN complementary DNA encoding the missing SMN protein...
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29079454/the-adenosine-a2a-receptor-agonist-t1-11-ameliorates-neurovisceral-symptoms-and-extends-the-lifespan-of-a-mouse-model-of-niemann-pick-type-c-disease
#13
Antonella Ferrante, Antonella Pezzola, Andrea Matteucci, Antonella Di Biase, Lucilla Attorri, Monica Armida, Alberto Martire, Yijuang Chern, Patrizia Popoli
Niemann-Pick C is a fatal neurovisceral disorder caused, in 95% of cases, by mutation of NPC1 gene. Therapeutic options are extremely limited and new "druggable" targets are highly warranted. We previously demonstrated that the stimulation of the adenosine A2A receptor (A2AR) normalized the pathological phenotype of cellular models of NPC1. Since the validation of A2ARs as a therapeutic target for NPC1 can be obtained only conducting studies in in vivo models of the disease, in the present paper, the effects of two agonists of A2ARs were evaluated in the mouse model Balb/c Npc1(nih), hereafter indicated as NPC1-/-...
October 25, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29079079/assessing-cognitive-functioning-in-females-with-rett-syndrome-by-eye-tracking-methodology
#14
Jaana Ahonniska-Assa, Orli Polack, Einat Saraf, Judy Wine, Tamar Silberg, Andreea Nissenkorn, Bruria Ben-Zeev
BACKGROUND: While many individuals with severe developmental impairments learn to communicate with augmentative and alternative communication (AAC) devices, a significant number of individuals show major difficulties in the effective use of AAC. Recent technological innovations, i.e., eye-tracking technology (ETT), aim to improve the transparency of communication and may also enable a more valid cognitive assessment. OBJECTIVES: To investigate whether ETT in forced-choice tasks can enable children with very severe motor and speech impairments to respond consistently, allowing a more reliable evaluation of their language comprehension...
October 10, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29075837/an-open-label-study-to-assess-the-feasibility-and-tolerability-of-rilmenidine-for-the-treatment-of-huntington-s-disease
#15
Benjamin R Underwood, Zeyn W Green-Thompson, Peter J Pugh, Stanley E Lazic, Sarah L Mason, Jules Griffin, P Simon Jones, James B Rowe, David C Rubinsztein, Roger A Barker
Preclinical data have shown that rilmenidine can regulate autophagy in models of Huntington's disease (HD), providing a potential route to alter the disease course in patients. Consequently, a 2-year open-label study examining the tolerability and feasibility of rilmenidine in mild-moderate HD was undertaken. 18 non-demented patients with mild to moderate HD took daily doses of 1 mg Rilmenidine for 6 months and 2 mg for a further 18 months followed by a 3-month washout period. The primary outcome was the number of withdrawals and serious adverse events...
October 26, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29072002/-clinical-trials-for-treatment-of-acute-lumbar-sprain-by-acupuncture-stimulation-of-yaotong-and-local-ashi-points-in-combination-with-patients-lumbar-movement
#16
Li-Li Liu, Jing Lu, Hui-Fang Ma
OBJECTIVE: To observe the clinical effect of acupuncture stimulation of "Yaotong"-point (one acupoint of balance acupuncture therapy) and Ashi-points combined with patients' lumbar movement in the treatment of acute lumbar sprain. METHODS: Forty-six acute lumbar sprain patients were randomized into treatment group (26 cases) and control group (20 cases) using a random number table. The patients of the treatment group were treated by acupuncture stimulation of "Yaotong"-point[above Yintang (EX-HN 3)] and local Ashi-points for 20 min, and were asked to move the waist simultaneously during acupuncture stimulation...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29064877/evidence-basis-for-regional-anesthesia-in-ambulatory-arthroscopic-knee-surgery-and-anterior-cruciate-ligament-reconstruction-part-ii-adductor-canal-nerve-block-a-systematic-review-and-meta-analysis
#17
Herman Sehmbi, Richard Brull, Ushma Jitendra Shah, Kariem El-Boghdadly, David Nguyen, Girish P Joshi, Faraj W Abdallah
BACKGROUND: Adductor canal block (ACB) has emerged as an effective analgesic regional technique for major knee surgeries in the last decade. Its motor-sparing properties make it particularly attractive for ambulatory knee surgery, but evidence supporting its use in ambulatory arthroscopic knee surgery is conflicting. This systematic review and meta-analysis evaluates the analgesic effects of ACB for ambulatory arthroscopic knee surgeries. METHODS: We conducted a comprehensive search of electronic databases for randomized controlled trials examining the analgesic effects of ACB compared to control or any other analgesic modality...
October 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29064257/effect-of-coadministered-water-on-the-in-vivo-performance-of-oral-formulations-containing-n-acetylcysteine-an-in-vitro-approach-using-the-dynamic-open-flow-through-test-apparatus
#18
Maximilian Sager, Felix Schneider, Philipp Jedamzik, Markus Wiedmann, Ellen Schremmer, Mirko Koziolek, Werner Weitschies
The drug plasma profile after oral administration of immediate release dosage forms can be affected by the human gastrointestinal physiology, the formulation, and the drug itself. In this work, we investigated the in vivo and in vitro performance of two formulations (granules vs. tablet) containing the highly soluble drug N-Acetylcysteine (BCS class I). Thereby, special attention was paid to the effect of the dosage form and the coadministration of water on drug release. Interestingly, the in vivo results from a pharmacokinetic study with 11 healthy volunteers indicated that the drug plasma concentrations were comparable for the tablet given with water as well as for the granules given with and without water...
November 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29060686/sparse-coding-of-ecog-signals-identifies-interpretable-components-for-speech-control-in-human-sensorimotor-cortex
#19
Kristofer E Bouchard, Alejandro F Bujan, Edward F Chang, Friedrich T Sommer
The concept of sparsity has proven useful to understanding elementary neural computations in sensory systems. However, the role of sparsity in motor regions is poorly understood. Here, we investigated the functional properties of sparse structure in neural activity collected with high-density electrocorticography (ECoG) from speech sensorimotor cortex (vSMC) in neurosurgical patients. Using independent components analysis (ICA), we found individual components corresponding to individual major oral articulators (i...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059133/a-phase-ib-randomized-controlled-study-to-evaluate-the-effectiveness-of-a-single-dose-of-the-nr2b-selective-n-methyl-d-aspartate-antagonist-mk-0657-on-levodopa-induced-dyskinesias-and-motor-symptoms-in-patients-with-parkinson-disease
#20
W Joseph Herring, Christopher Assaid, Kerry Budd, Ryan Vargo, Ralph S Mazenko, Christopher Lines, Aaron Ellenbogen, Leo Verhagen Metman
OBJECTIVES: Blockade of N-methyl-D-aspartate receptors containing the NR2B subunit has been shown to be therapeutic in animal models of Parkinson disease (PD). However, findings with investigational NR2B receptor antagonists in PD patients have been mixed. The objective of this study was to evaluate the effects of the NR2B selective N-methyl-D-aspartate receptor antagonist MK-0657 on levodopa-induced dyskinesias and motor symptoms in PD patients. METHODS: A randomized, double-blind, single-dose, 2-period crossover study was conducted in 22 patients with PD and levodopa-induced peak-dose dyskinesias...
November 2017: Clinical Neuropharmacology
keyword
keyword
20960
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"