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Language Delay

Kyle T Fletcher, Erin M Wolf Horrell, John Ayugi, Catherine Irungu, Maria Muthoka, Liza M Creel, Cathy Lester, Matthew L Bush
OBJECTIVE: The purpose of this study was to examine the literature regarding the natural history and rehabilitative outcomes of sensorineural hearing loss from congenital cytomegalovirus infections. DATA SOURCES AND STUDY ELIGIBILITY CRITERIA: A systematic search was performed in PubMed, PsychINFO, CINAHL, and Web of Science to identify peer-reviewed research. Eligible studies were those containing original peer-reviewed research in English addressing either the natural history or rehabilitative outcomes of sensorineural hearing loss (SNHL) in congenital cytomegalovirus (cCMV)...
June 15, 2018: Otology & Neurotology
Avishek Hazra, M E Khan, Subrato Kumar Mondal
Over 90% of households in rural Uttar Pradesh, the most populous state of India, have at least one mobile phone. However, ownership of mobile phone among women is quite low. Implementation research was conducted in Uttar Pradesh to examine (a) whether providing information on selected maternal and child health (MCH) behaviors to a husband's mobile phone would enhance the man's knowledge and lead to discussions in their family, and (b) whether such discussions would help in the adoption of healthy practices...
June 14, 2018: Journal of Health Communication
B Salamanca-Zarzuela, F Morales-Luego, C Alcalde-Martin, F Centeno-Malfaz
AIM: Retrospective analysis of the neurodevelopment in the first two years of life in patients with severe congenital heart disease. PATIENTS AND METHODS: Out of 89 patients with severe congenital heart disease 19 were excluded due to a history of prematurity and/or chromosomopathy, four due to a history of ischemic stroke and two due to lack of medical history. Denver Test (DT) results at 2, 6, 12, 15 and 18 months, and results in motor, language and social interaction fields were achieved...
June 16, 2018: Revista de Neurologia
Jihang Luo, Di Fang, Wenjuan Qiu, Bing Xiao, Yanjie Fan, Jun Ye, Lianshu Han, Huiwen Zhang, Yongguo Yu, Lili Liang, Xuefan Gu
OBJECTIVE: To determine the genetic etiology and clinical characteristics of 2 boys featuring development delay (DD). METHODS: Routine chromosomal banding was performed to analyze the karyotypes of the patients and their parents. Single nucleotide polymorphism array (SNP array) analysis was employed to identify pathogenic deletion/duplication of chromosomes, and quantitative real-time PCR (qPCR) was performed to confirm the results. RESULTS: Patient 1 showed a global developmental delay, especially impaired language development, seizures, behavioral problems belonging to the autism spectrum and mild facial dysmorphism...
June 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
Shelley L Bredin-Oja, Heather Fielding, Kandace K Fleming, Steven F Warren
Purpose: The purpose of this study was to investigate the reliability of an automated language analysis system, the Language Environment Analysis (LENA), compared with a human transcriber to determine the rate of child vocalizations during recording sessions that were significantly shorter than recommended for the automated device. Method: Participants were 6 nonverbal male children between the ages of 28 and 46 months. Two children had autism diagnoses, 2 had Down syndrome, 1 had a chromosomal deletion, and 1 had developmental delay...
June 11, 2018: American Journal of Speech-language Pathology
Enrico Bertini, Ginevra Zanni, Eugen Boltshauser
The terminology of nonprogressive congenital ataxia (NPCA) refers to a clinically and genetically heterogeneous group of disorders characterized by congenital or early-onset ataxia, but no progression or even improvement on follow-up. Ataxia is preceded by muscular hypotonia and delayed motor (and usually language) milestones. We exclude children with prenatal, perinatal, and postnatal acquired diseases, malformations other than cerebellar hypoplasia, and defined syndromic disorders. Patients with NPCA have a high prevalence of cognitive and language impairments, in addition to increased occurrence of seizures, ocular signs (nystagmus, strabismus), behavior changes, and microcephaly...
2018: Handbook of Clinical Neurology
Yifan Zheng, Qi Wu, Fengjuan Su, Yingying Fang, Jinsheng Zeng, Zhong Pei
BACKGROUND: Several studies have found that bilingualism can delay the age of onset of Alz-heimer disease (AD). The interpretation of these findings is that switching between two languages can enhance cognitive reserve. However, some studies have provided inconsistent results. Diverse language pairs used by the bilinguals in different studies may contribute to the discrepancies. Cantonese and Mandarin are widely used in southern China, and regarded as bilingualism. The present study aims to determine if Cantonese/Mandarin bilingualism can delay the onset of AD...
June 8, 2018: Dementia and Geriatric Cognitive Disorders
Jeffrey Kay, Muzammil Memon, Ajay Shah, Yi-Meng Yen, Kristian Samuelsson, Devin Peterson, Nicole Simunovic, Helene Flageole, Olufemi R Ayeni
PURPOSE: To evaluate the association between surgical timing and the incidence of secondary meniscal or chondral damage in children and adolescents with anterior cruciate ligament (ACL) ruptures. METHODS: Three electronic databases, PubMed, MEDLINE, and EMBASE, were systematically searched from database inception until October 16, 2017 by two reviewers independently and in duplicate. The inclusion criteria were English language studies that reported the incidence of meniscal and articular cartilage damage in children or adolescent athletes with ACL injuries as well as the timing of their ACL reconstruction (ACLR)...
June 6, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Mohsen Mohandes, Sergio Rojas, Jordi Guarinos, Francisco Fernández, Cristina Moreno, Mauricio Torres, Germán Cediel, Ramón De Castro, Alfredo Bardaji
Introduction: There are inconclusive data about the potential delay of procedure time in emergent percutaneous coronary intervention (PCI) by radial compared with femoral approach in patients with ST-segment elevation myocardial infarction (STEMI). Aims: The purpose of the current study is to conduct a comprehensive meta-analysis of controlled randomized trials (CRTs) comparing the procedure time in STEMI patients undergoing emergent PCI with radial versus femoral access...
January 2018: Heart Views: the Official Journal of the Gulf Heart Association
Stacy D O'Connor, Ramin Khorasani, Stephen M Pochebit, Ronilda Lacson, Katherine P Andriole, Anuj K Dalal
BACKGROUND:  Failure of timely test result follow-up has consequences including delayed diagnosis and treatment, added costs, and potential patient harm. Closed-loop communication is key to ensure clinically significant test results (CSTRs) are acknowledged and acted upon appropriately. A previous implementation of the Alert Notification of Critical Results (ANCR) system to facilitate closed-loop communication of imaging CSTRs yielded improved communication of critical radiology results and enhanced adherence to institutional CSTR policies...
April 2018: Applied Clinical Informatics
Chittaranjan Andrade
Valproate and formulations thereof are approved for the management of seizure disorders, bipolar disorder, and migraine. Valproate is also used for many off-label indications. Unfortunately, data from observational studies indicate that valproate is perhaps the most teratogenic drug in the neuropsychiatric pharmacopeia. It is significantly more teratogenic than many other antiepileptic drugs (AEDs). In observational studies, gestational exposure to valproate is also associated with higher risks of cognitive, language, and psychomotor delay during early childhood and possibly with an increased risk of autism, as well...
May 29, 2018: Journal of Clinical Psychiatry
Kamila Polišenská, Svetlana Kapalková, Monika Novotková
Purpose: The study aims to describe receptive language skills in children with intellectual disability (ID) and to contribute to the debate on deviant versus delayed language development. This is the 1st study of receptive skills in children with ID who speak a Slavic language, providing insight into how language development is affected by disability and also language typology. Method: Twenty-eight Slovak-speaking children participated in the study (14 children with ID and 14 typically developing [TD] children matched on nonverbal reasoning abilities)...
June 5, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
Annika Linke, Elizabeth Roach-Fox, Ellen Vriezen, Asuri Narayan Prasad, Rhodri Cusack
Mirror writing is often produced by healthy children during early acquisition of literacy, and has been observed in adults following neurological disorders or insults. The neural mechanisms responsible for involuntary mirror writing remain debated, but in healthy children, it is typically attributed to the delayed development of a process of overcoming mirror invariance while learning to read and write. We present an unusual case of sudden-onset, persistent mirror writing in a previously typical seven-year-old girl...
June 2, 2018: Neuropsychologia
Deepti Putcha, Scott M McGinnis, Michael Brickhouse, Bonnie Wong, Janet C Sherman, Bradford C Dickerson
Posterior Cortical Atrophy (PCA) is a neurodegenerative syndrome that typically presents with predominant visual and spatial impairments. The early diagnostic criteria specify a relative sparing of functioning in other cognitive domains, including executive functions, language, and episodic memory, yet little is known of the cognitive profile of PCA as the disease progresses. Studies of healthy adults and other posterior cortical lesion patients implicate posterior parietal and temporal regions in executive functions of working memory and verbal fluency, both of which may impact episodic memory...
May 10, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Jill de Villiers, Chunyan Ning, Xueman Lucy Liu, Yi Wen Zhang, Fan Jiang
The comprehension of paired wh-questions is examined in child Mandarin, to compare the age of acquisition with that of children speaking European languages like English and German. In Study 1, participants were 734 Mandarin speakers aged 2;6-7;11, drawn from four regions of China. Results reveal a striking parallel between the acquisition of exhaustive answers in Mandarin and that in languages with wh-movement. The significant correlation with children's exhaustive interpretations of the universal quantifier every (dou) also parallels findings in English...
June 1, 2018: Journal of Psycholinguistic Research
Caterina Neri, Carmen De Luca, Luisa D'oria, Angelo Licameli, Marta Nucci, Marcella Pellegrino, Alessandro Caruso, Marco De Santis
BACKGROUND: The objective of the present study is to review the literature regarding the management of fertile patients under lithium treatment for bipolar disorder and to report the experience of our Teratology Information Service over the past thirteen years in managing women treated with lithium during preconception, pregnancy and breastfeeding. METHODS: This research focuses on a selective review of the literature and a retrospective survey has been carried out on fertile women under lithium treatment who called our service at A...
June 2018: Minerva Ginecologica
A Kielar, T Deschamps, R Jokel, J A Meltzer
Patients with Primary Progressive Aphasia (PPA) may react to linguistic stimuli differently than healthy controls, reflecting degeneration of language networks and engagement of compensatory mechanisms. We used magnetoencephalography (MEG) to evaluate oscillatory neural responses in sentence comprehension, in patients with PPA and age-matched controls. Participants viewed sentences containing semantically and syntactically anomalous words that evoke distinct oscillatory responses. For age-matched controls, semantic anomalies elicited left-lateralized 8-30 Hz power decreases distributed along ventral brain regions, whereas syntactic anomalies elicited bilateral power decreases in both ventral and dorsal regions...
2018: NeuroImage: Clinical
R A Brown, H Dakkak, J A Seabrook
Maternal drug use during lactation may have adverse effects on the health of their children. Two common drugs used during this period are alcohol and cannabis. A literature search was conducted using PubMed, CINAHL, Nursing and Allied Health, and Google Scholar with the following search terms: marijuana, cannabis, THC, alcohol, ethanol, breastfeeding, lactation, and breastmilk. The search strategy was restricted to papers since the year 2000, and limited to English language journals. Reference lists were also used to capture any articles that were missed from the database searches...
May 23, 2018: Journal of Neonatal-perinatal Medicine
Karen Meneses, Silvia Gisiger-Camata, Rachel Benz, Dheeraj Raju, Jennifer R Bail, Tanya J Benitez, Dorothy Pekmezi, Patrick McNees
AIM: This study was a pilot test of the Latina Breast Cancer Survivorship Intervention, a survivorship self-management intervention delivered via telephone. MATERIALS AND METHODS: This study used a wait-list control design with random assignment to either (1) support and early education or (2) support and delayed education. Latina breast cancer survivors were recruited through the Florida Cancer Data System Registry. Latinas with stage I-III breast cancer who completed primary cancer treatment 3 years prior to study enrollment were eligible...
January 2018: Women's Health
L X Yang, X Tang, N Zhou, M Zhang, J Yan
Objective: To evaluate the cognitive function of adult OSAHS patients by MoCA-BJ, and to evaluate the reliability and efficacy of MoCA-BJ. Method: A study was conducted on the cognitive function of 94 patients with mild, moderate and severe OSAHS and 28 healthy controls using the MoCA-BJ and the simple mental state examination scale (MMSE). After 14 days, 10 subjects in the healthy control group were tested for MoCA-BJ again. The internal consistency of MoCA-BJ and the Pearson correlation coefficient were used to test the retest reliability...
January 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
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