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Behavioral Therapy

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https://www.readbyqxmd.com/read/28108936/a-group-mediated-physical-activity-intervention-in-older-knee-osteoarthritis-patients-effects-on-social-cognitive-outcomes
#1
Brian C Focht, Matthew J Garver, Alexander R Lucas, Steven T Devor, Charles F Emery, Kevin V Hackshaw, Ciaran M Fairman, Jessica Bowman, W Jack Rejeski
The objective of the present study was to compare a group-mediated cognitive behavioral (GMCB) physical activity intervention with traditional exercise therapy (TRAD) upon select social cognitive outcomes in sedentary knee osteoarthritis (knee OA) patients. A total of 80 patients (mean age = 63.5 years; 84% women) were recruited using clinic and community-based strategies to a 12-month, single-blind, two-arm, randomized controlled trial. Mobility-related self-efficacy, self-regulatory self-efficacy (SRSE), and satisfaction with physical function (SPF) were assessed at baseline, 3, and 12 months...
January 20, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28108386/trajectory-of-improvement-in-children-and-adolescents-with-chronic-migraine-results-from-the-cognitive-behavioral-therapy-and-amitriptyline-trial
#2
John W Kroner, James Peugh, Susmita M Kashikar-Zuck, Susan L LeCates, Janelle R Allen, Shalonda K Slater, Marium Zafar, Marielle A Kabbouche, Hope L O'Brien, Chad E Shenk, Ashley M Kroon Van Diest, Andrew D Hershey, Scott W Powers
: We compared headache frequency trajectories between clinical trial participants who received cognitive behavioral therapy plus amitriptyline (CBT+A) or headache education plus amitriptyline (HE+A) to determine if there was differential time course of treatment response between the groups. 135 patients (age 10-17) diagnosed with chronic migraine participated, attending 8 one-hour one-on-one CBT or HE sessions with a trained psychologist for 8 weekly sessions, 2 sessions at weeks 12 and 16, and a post-treatment visit at week 20...
January 17, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28108274/the-crosstalk-between-wnt-%C3%AE-catenin-signaling-pathway-with-dna-damage-response-and-oxidative-stress-implications-in-cancer-therapy
#3
REVIEW
Ansar Karimaian, Maryam Majidinia, Hossein Bannazadeh Baghi, Bahman Yousefi
DNA repair is essential for maintaining genomic integrity in cells. The dependence of cancer cell survival on proper DNA repair provides an opportunity to treat defective tumors by DNA damaging agents. Not only Wnt signaling has important functions in controlling gene expression, as well as cell polarity, adhesion and behavior, it also highly interacts with DNA damage response (DDR) in different levels. Furthermore, oxidative stress, which is responsible for majority of DNA lesions, affects Wnt signaling in different ways...
January 11, 2017: DNA Repair
https://www.readbyqxmd.com/read/28108155/association-of-health-professional-leadership-behaviors-on-health-promotion-practice-beliefs
#4
Jacqueline D Stone, Harolyn M E Belcher, Prince Attoh, Michelle D'Abundo, Tao Gong
BACKGROUND: Leadership is a process by which an individual influences a group or individual to achieve a common goal, in this case health promotion for individuals with disabilities. OBJECTIVES: (1) To examine the association between the transformational leadership behaviors of the Association of University Centers on Disabilities (AUCD) network professionals and their practice beliefs about health promotion activities, specifically cardiovascular fitness and healthy weight, for people with disabilities...
January 5, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28108059/self-views-in-social-anxiety-disorder-the-impact-of-cbt-versus-mbsr
#5
Matthew D Thurston, Philippe Goldin, Richard Heimberg, James J Gross
This study examines the impact of Cognitive-Behavioral Group Therapy (CBGT) versus Mindfulness-Based Stress Reduction (MBSR) versus Waitlist (WL) on self-views in patients with social anxiety disorder (SAD). One hundred eight unmedicated patients with SAD were randomly assigned to 12 weeks of CBGT, MBSR, or WL, and completed a self-referential encoding task (SRET) that assessed self-endorsement of positive and negative self-views pre- and post-treatment. At baseline, 40 healthy controls (HCs) also completed the SRET...
January 10, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28107854/mindfulness-based-group-therapy-for-systemic-lupus-erythematosus-a-first-exploration-of-a-promising-mind-body-intervention
#6
Danny Horesh, Ittai Glick, Renen Taub, Nancy Agmon-Levin, Yehuda Shoenfeld
Psychological effects related to systemic lupus erythematosus (SLE) are tremendous. While a variety of psychological treatments have been applied to assist SLE patients, the effects of mindfulness practice were never documented in SLE. Mindfulness-based psychotherapy includes several techniques, including body-scan, breathing exercises, and full awareness during daily activities. In this case report, we present a first attempt at conducting mindfulness-based group therapy among SLE patients. Six female SLE patients participated in an 8-week program...
February 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28107849/attitudes-to-and-beliefs-about-animal-assisted-therapy-for-children-with-disabilities
#7
Esther Yap, Adam Scheinberg, Katrina Williams
OBJECTIVES: This study assessed the attitudes and beliefs surrounding animal-assisted therapy (AAT) for the rehabilitation of children with disabilities at the Royal Children's Hospital (RCH), focusing specifically on cerebral palsy (CP), autism spectrum disorder (ASD) and acquired brain injury (ABI). This was an initial step to inform future AAT research and to understand the feasibility of interventions. DESIGN/SETTING/OUTCOME MEASURES: An online survey asking participants their opinions about the inclusion of AAT, and potential barriers to its introduction in a tertiary hospital setting was advertised on the RCH Intranet from 3 March 2015 to 3 April 2015...
February 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28107643/does-psychological-well-being-change-following-treatment-an-exploratory-study-on-outpatients-with-eating-disorders
#8
Elena Tomba, Lucia Tecuta, Romana Schumann, Donatella Ballardini
Psychological well-being changes following cognitive-behavioral therapy-based treatment were investigated in outpatients with eating disorders (ED). While it is known that CBT reduces symptomatology in EDs, less is known about how changes in positive functioning may ensue. One-hundred and eighty five ED outpatients were analyzed for pre-treatment and post-treatment changes in psychological well-being (PWB) by last observation carried forward - Wilcoxon signed rank tests. Significant gains in all PWB dimensions were found, with moderate effect size correlations in environmental mastery (r=-...
January 7, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28107430/discontinuation-from-antiretroviral-therapy-a-continuing-challenge-among-adults-in-hiv-care-in-ethiopia-a-systematic-review-and-meta-analysis
#9
Hailay Abrha Gesesew, Paul Ward, Kifle Woldemichael Hajito, Garumma Tolu Feyissa, Leila Mohammadi, Lillian Mwanri
BACKGROUND: Discontinuation of antiretroviral therapy (ART) reduces the immunological benefit of treatment and increases complications related to human immune-deficiency virus (HIV). However, the risk factors for ART discontinuation are poorly understood in developing countries particularly in Ethiopia. This review aimed to assess the best available evidence regarding risk factors for ART discontinuation in Ethiopia. METHODS: Quantitative studies conducted in Ethiopia between 2002 and 2015 that evaluated factors associated with ART discontinuation were sought across six major databases...
2017: PloS One
https://www.readbyqxmd.com/read/28106917/is-there-an-optimal-length-of-psychological-treatment-for-eating-disorder-pathology
#10
Caroline Bell, Glenn Waller, Roz Shafran, Jaime Delgadillo
Treatment guidelines for eating disorders (ED) are unclear about the optimal length of psychological care. We aimed to investigate associations between treatment duration and changes in ED pathology. Data for 164 outpatients accessing psychological interventions for ED were analyzed using MANOVA. We tested associations between number of therapy sessions and pre-post treatment changes in clinical outcomes (EDE-Q global scores, binge eating, purging); adjusting for baseline measures, diagnoses, and treatment type...
January 20, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28106670/reward-motivation-and-emotion-of-pain-and-its-relief
#11
Frank Porreca, Edita Navratilova
The experience of pain depends on interpretation of context and past experience that guide the choice of an immediate behavioral response and influence future decisions of actions to avoid harm. The aversive qualities of pain underlie its physiological role in learning and motivation. In this review, we highlight findings from human and animal investigations that suggest that both pain, and the relief of pain, are complex emotions that are comprised of feelings and their motivational consequences. Relief of aversive states, including pain, is rewarding...
January 12, 2017: Pain
https://www.readbyqxmd.com/read/28106666/a-tailored-guided-internet-based-cognitive-behavioral-intervention-for-patients-with-rheumatoid-arthritis-as-an-adjunct-to-standard-rheumatological-care-results-of-a-randomized-controlled-trial
#12
M Ferwerda, S van Beugen, H van Middendorp, S Spillekom-van Koulil, A R T Donders, H Visser, E Taal, M C W Creemers, P C L M van Riel, A W M Evers
For patients with chronic pain conditions such as rheumatoid arthritis (RA), who experience elevated levels of distress, tailored guided internet-based cognitive behavioral treatment may be effective in improving psychological and physical functioning, and reducing impact the impact of RA on daily life. A multicenter randomized controlled trial was conducted for RA patients with elevated levels of distress asassessed by a disease-specific measure. The control group (n=71) received standard care and the intervention group (n= 62) additionally received an internet-based tailored cognitive-behavioral intervention...
January 12, 2017: Pain
https://www.readbyqxmd.com/read/28106652/prospective-outcomes-of-a-pelvic-floor-rehabilitation-program-including-vaginal-electrogalvanic-stimulation-for-urinary-defecatory-and-pelvic-pain-symptoms
#13
Jennifer J Schmitt, Ruchira Singh, Amy L Weaver, Kristin C Mara, Randina R Harvey-Springer, Felecia R Fick, John A Occhino
OBJECTIVES: This study evaluated our experience after implementing a pelvic floor rehabilitation program including behavioral modification, biofeedback, and vaginal electrogalvanic stimulation (EGS). METHODS: This prospective cohort study evaluated outcomes of patients with pelvic floor dysfunction (urinary or defecatory dysfunction, pelvic pain/dyspareunia) who underwent pelvic floor rehabilitation. Patients received 4 to 7 sessions (1 every 2 weeks) including biofeedback and concluded with 30 minutes of vaginal EGS...
January 18, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28106296/pten-plays-dual-roles-as-a-tumor-suppressor-in-osteosarcoma-cells
#14
Yongming Xi, Yan Chen
Osteosarcoma (OS) is the most common primary bone cancer, which occurs primarily in children and adolescents. Functional loss of the tumor suppressor PTEN has been demonstrated in bone malignancies including OS. We have recently reported that Pten expression inversely correlates with OS aggressiveness in mouse models. However, the mechanism whereby PTEN exerts its anti-tumor effect remains unknown. In this study, we first examined the expression of PTEN in human OS cell lines including U2OS, MG63 and Saos-2, and found that PTEN expression is reduced as compared to normal human osteoblasts...
January 20, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28105576/effects-of-cognitive-behavioral-therapy-for-insomnia-and-armodafinil-on-quality-of-life-in-cancer-survivors-a-randomized-placebo-controlled-trial
#15
Anita R Peoples, Sheila N Garland, Michael L Perlis, Josée Savard, Charles E Heckler, Charles S Kamen, Julie L Ryan, Karen M Mustian, Michelle C Janelsins, Luke J Peppone, Gary R Morrow, Joseph A Roscoe
PURPOSE: Cancer-related insomnia is associated with diminished quality of life (QOL), suggesting that improvement in insomnia may improve QOL in cancer survivors. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve insomnia, but less is known regarding its effect on QOL and whether improvement in insomnia corresponds to improved QOL. The present analysis examines the effects of CBT-I, with and without armodafinil, on QOL both directly and indirectly through improvements of insomnia...
January 19, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28105557/the-anticancer-drug-sunitinib-promotes-autophagyand-protects-from-neurotoxicity-in-an-hiv-1-tat-model-of-neurodegeneration
#16
Jerel A Fields, Jeff Metcalf, Cassia Overk, Anthony Adame, Brian Spencer, Wolfgang Wrasidlo, Jazmin Florio, Edward Rockenstein, Johnny J He, Eliezer Masliah
Despite the success of antiretroviral therapies to control systemic HIV-1 infection, the prevalence of HIV-associated neurocognitive disorders (HANDs) has not decreased among aging patients with HIV. Autophagy pathway alterations, triggered by HIV-1 proteins including gp120, Tat, and Nef, might contribute to the neurodegenerative process in aging patients with HAND. Although no treatments are currently available to manage HAND, we have previously shown that sunitinib, an anticancer drug that blocks receptor tyrosine-kinase and cyclin kinase pathways, might be of interest...
January 19, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28105501/-diagnostics-and-multimodal-treatment-of-depression-in-old-age-new-developments
#17
Gerhard W Eschweiler
Depressive disorders in elderly persons are frequent and can either first be manifested at a younger age and show a recurrent pattern during later life (ICD 10, F33.*) or have an onset beyond 60 years, which is termed late onset depression (LOD). This LOD has a higher tendency to chronification and implies an increased risk of progression, especially to vascular dementia. The multifactorial genesis of depression in old age includes psychosocial, vascular and metabolic factors and requires multimodal therapy modules at the biological and psychosocial level, which is now increasingly being empirically proven...
January 19, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28105218/involvement-of-cancer-derived-igg-in-the-proliferation-migration-and-invasion-of-bladder-cancer-cells
#18
Zhengzuo Sheng, Yang Liu, Caipeng Qin, Zhenhua Liu, Yeqing Yuan, Huaqi Yin, Xiaoyan Qiu, Tao Xu
It is widely accepted that immunoglobulin (Ig), the classical immune molecule, is extensively expressed in many cell types other than B-cells (non-B-IgG), including some malignant cells. The expression of Ig in malignant cells has been associated with a poor prognosis. In the present study, immunohistochemical analysis detected strong positive staining of IgG in three bladder cancer cell lines, the cancer cells in 77 bladder cancer patient samples and the cells in 3 cystitis glandularis tissue samples, while negative staining was observed in 4 specimens of normal transitional epithelial tissues...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28105095/preliminary-results-of-a-non-invasive-method-to-measure-tumor-size-and-distribution-in-vivo
#19
Shu-Ling Fu, Chien-An Chen, Ling-Chien Hung, Moon-Sing Lee, Wen-Yen Chiou, Hon-Yi Lin, Yu-Chieh Su, Ching-Chih Lee, Shih-Kai Hung
Molecular imaging of reporter gene expression in cancer cells can provide rapid, sensitive and non-invasive monitoring of tumor behavior. The aim of the present study was to establish a non-invasive method to measure tumor size and distribution in vivo. Briefly, H-Ras-transformed cells were stably transfected with a plasmid containing the luciferase gene (Luc), designated as Ras/Luc. Ras/Luc cells were injected into the back or tail vein of nude BALB/cAnN-Foxn1nu/CrlNarl mice (age, 6-8 weeks). Mice were subsequently administered D-luciferin via intra-peritoneal injection, prior to image acquisition...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28105067/current-state-and-future-prospects-for-psychosomatic-medicine-in-japan
#20
REVIEW
Masato Murakami, Yoshihide Nakai
In this article, we describe the history and current state of psychosomatic medicine (PSM) in Japan and propose measures that could be considered based on our view of the future prospects of PSM in Japan. The Japanese Society of PSM (JSPM) was established in 1959, and the first Department of Psychosomatic Internal Medicine in Japan was established at Kyushu University In 1963. PSM in Japan has shown a prominent, unique development, with 3,300 members (as of March 2016), comprised of 71.6% of medical doctors including psychosomatic internal medicine (PIM) specialists, general internists, psychiatrists, pediatricians, obstetricians and gynecologists, dentists, dermatologists, and others...
2017: BioPsychoSocial Medicine
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