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HCV, HBV, infection , fever

Sheila Makiala-Mandanda, Frédéric Le Gal, Nadine Ngwaka-Matsung, Steve Ahuka-Mundeke, Richard Onanga, Berthold Bivigou-Mboumba, Elisabeth Pukuta-Simbu, Athenaïs Gerber, Jessica L Abbate, Dieudonné Mwamba, Nicolas Berthet, Eric Maurice Leroy, Jean-Jacques Muyembe-Tamfum, Pierre Becquart
The majority of patients with acute febrile jaundice (>95%) identified through a yellow fever surveillance program in the Democratic Republic of Congo (DRC) test negative for antibodies against yellow fever virus. However, no etiological investigation has ever been carried out on these patients. Here, we tested for hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D (HDV), and hepatitis E (HEV) viruses, all of which can cause acute febrile jaundice, in patients included in the yellow fever surveillance program in the DRC...
May 2017: Journal of Clinical Microbiology
Zohair Ahmed, Saurabh K Bansal, Sonu Dhillon
A 21-year-old male with no significant past medical history, presented with right upper quadrant (RUQ) abdominal pain along with fevers and chills. Lab work revealed leukocytosis, anemia, and slightly elevated alkaline phosphatase. Viral serology for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus were negative and he was immunocompetent. Computed tomography imaging revealed hepatic abscesses, the largest measuring 9.5 cm. Empiric antibiotics were started and percutaneous drains were placed in the abscesses...
March 28, 2015: World Journal of Gastroenterology: WJG
Giada Melis, Giorgio Pia, Ilenia Piras, Massimo Tusconi
The management of patients with HIV infection who have comorbidity with psychiatric disorders, is a problem that is encountered relatively frequently in Emergency Departments. This retrospective study aims to evaluate the characteristics of HIV-infected patients who have been admitted for mental disorders and other conditions to an Emergency Department (ED) of Sardinia, Italy, in 2013. Regarding the associated psychiatric condition (25.5% of total sample) 46.3% had mood disorders, 38.9% psychotic disorders and 14...
June 2015: Internal and Emergency Medicine
R Kishk, H Aboul Atta, M Ragheb, M Kamel, L Metwally, N Nemr
Chronic hepatitis C virus (HCV) infection combined with occult hepatitis B virus (HBV) infection has been associated with increased risk of hepatitis, cirrhosis and hepatocellular carcinoma. This study aimed to determine the prevalence of occult HBV infection among Egyptian chronic HCV patients, the genotype and occurrence of surface gene mutations of HBV and the impact of co-infection on early response to treatment. The study enrolled 162 chronic HCV patients from Ismailia Fever Hospital, Egypt, who were HBV surface antigen-negative...
March 13, 2014: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
Xianguo Wang, Quanfu Zhang, Fen Hao, Xunian Gao, Wei Wu, Minyao Liang, Zhihua Liao, Shuhong Luo, Weiwen Xu, Dexin Li, Shiwen Wang
It is critical to develop a cost-effective detection kit for rapid diagnosis and on-site detection of severe fever with thrombocytopenia syndrome virus (SFTSV) infection. Here, an immunochromatographic assay (ICA) to detect SFTSV infection is described. The ICA uses gold nanoparticles coated with recombinant SFTSV for the simultaneous detection of IgG and IgM antibodies to SFTSV. The ICA was developed and evaluated by using positive sera samples of SFTSV infection (n = 245) collected from the CDC of China. The reference laboratory diagnosis of SFTSV infection was based on the "gold standard"...
2014: BioMed Research International
Zhaojing Cheng, Baotong Zhou, Xiaochun Shi, Yao Zhang, Lifan Zhang, Limeng Chen, Xiaoqing Liu
BACKGROUND: Chronic hepatitis C virus (HCV) infection can affect multiple organ systems and cause a variety of extrahepatic manifestations (EMs). We sought to assess the constituent ratio of EMs in Chinese patients with chronic HCV infection and identify the clinical and biological factors associated with EM. METHODS: The medical records of 297 patients with chronic HCV infection were analyzed and demographic and epidemiological information was collected. The diagnosis of chronic HCV infection was based on positive anti-HCV combined with a positive HCV-RNA or at least two times of elevated aminotransferases attributable to HCV infection...
2014: Chinese Medical Journal
Xiaolei Zhang, Huaping Dai, Yan Liu
SESSION TITLE: Infectious Disease Case Reports Posters IIISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: The Hyper IgE Syndrome (HIES) is a rare, complex primary immunodeficiency. Here we report a case of HIES combined with natural killer cell deficiency, which has not been documented in the literature before. CASE PRESENTATION: A 20-year-old male patient was admitted to hospital with cough, dyspnea and low-grade fever...
March 1, 2014: Chest
Qian Zhao, Hai-ping Liu, Yi-jin Gu, Wen-ming Cong
OBJECTIVE: To evaluate the clinicopathological features and prognosis of primary hepatic lymphoma (PHL). METHODS: Thirty-five patients with PHL who underwent surgical resection and were confirmed by pathology in our hospital from 1982 to 2012 were re-evaluated for clinicopathological data, including their symptoms, radiological features, recurrence interval, histopathological properties and prognosis. RESULTS: Of the 35 patients, 25 were men (71...
September 2013: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Joseph Humphrey Kofi Bonney, Mubarak Osei-Kwasi, Theophilus Korku Adiku, Jacob Samson Barnor, Robert Amesiya, Chrysantus Kubio, Lawson Ahadzie, Stephan Olschläger, Michaela Lelke, Beate Becker-Ziaja, Meike Pahlmann, Stephan Günther
BACKGROUND: Viral hemorrhagic fevers (VHF) are acute diseases associated with bleeding, organ failure, and shock. VHF may hardly be distinguished clinically from other diseases in the African hospital, including viral hepatitis. This study was conducted to determine if VHF and viral hepatitis contribute to hospital morbidity in the Central and Northern parts of Ghana. METHODOLOGY/PRINCIPAL FINDINGS: From 2009 to 2011, blood samples of 258 patients with VHF symptoms were collected at 18 hospitals in Ashanti, Brong-Ahafo, Northern, Upper West, and Upper East regions...
2013: PLoS Neglected Tropical Diseases
Erik De Clercq
Vaccination is possible to prevent infections with some viruses: hepatitis B virus (HBV), varicella-zoster virus (VZV), influenza A and B viruses, Yellow fever virus and poliovirus; but not for others: human immunodeficiency virus (HIV), hepatitis C virus (HCV), herpes simplex virus (HSV), cytomegalovirus (CMV), and most hemorrhagic fever viruses (HFV) (except for Yellow fever virus). Antiviral therapy is obviously needed to control those infections that are not amenable to prophylaxis by vaccination, but is also highly desirable for those infections where vaccination has not been implemented or did not fulfill its premises for complete protection...
March 15, 2013: Biochemical Pharmacology
Abdel Motaal Mohamed Ahmed, Mohamed B Galib
BACKGROUND: Aside from acute viral hepatitides intracellular cholestasis is seen less often with the use of certain drugs, contrast media, leptospirosis and congenital hyperbilirubinaemias. Types of liver injuries complicating malaria usually take the form of acute hepatitis or haemolytic anaemias rather than cholestasis. We report here a rare presentation where a typical intracellular cholestatic picture complicated malaria falciparum in a patient residing in an endemic area. PATIENT AND METHODS: A 55 year old bank manager presented with malaria fever and deep jaundice for investigations...
March 2012: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
Yu-Ting Liou, Jing-Long Huang, Liang-Shiou Ou, Yu-Hsuan Lin, Kuang-Hui Yu, Shue-Fen Luo, Huei-Huang Ho, Lieh-Bang Liou, Kuo-Wei Yeh
BACKGROUND/PURPOSE: Cryoglobulinemic vasculitis is a systemic vasculitis resulting from circulating immune complex deposition in the small vessels and is characterized by variable clinical features, including purpura, Raynaud's syndrome, ulcerations, arthralgia, glomerulonephritis, and peripheral neuropathy. Cryoglobulinemia can also result from hepatitis C virus (HCV) infection. The clinical spectrum and associated or underlying diseases of cryoglobulinemia in different age groups is not well understood...
February 2013: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Jacek Dutkiewicz, Ewa Cisak, Jacek Sroka, Angelina Wójcik-Fatla, Violetta Zając
There are two main groups of biological agents regarded as occupational hazards: allergenic and/or toxic agents forming bioaerosols, and agents causing zoonoses and other infectious diseases. Bioaerosols occurring in the agricultural work environments comprise: bacteria, fungi, high molecular polymers produced by bacteria (endotoxin) or by fungi (β-glucans), low molecular secondary metabolites of fungi (mycotoxins, volatile organic compounds) and various particles of plant and animal origin. All these agents could be a cause of allergic and/or immunotoxic occupational diseases of respiratory organ (airways inflammation, rhinitis, toxic pneumonitis, hypersensitivity pneumonitis and asthma), conjunctivitis and dermatitis in exposed workers...
2011: Annals of Agricultural and Environmental Medicine: AAEM
Charlotte H B S van den Berg, Bart P X Grady, Janke Schinkel, Thijs van de Laar, Richard Molenkamp, Robin van Houdt, Roel A Coutinho, Debbie van Baarle, Maria Prins
BACKGROUND & AIMS: Since acute hepatitis C virus (HCV) infection is often asymptomatic, it is difficult to examine the rate and determinants of spontaneous clearance. Consequently, these studies are subject to bias, which can potentially lead to biased rates of viral clearance and risk estimates. We evaluated determinants of spontaneous HCV clearance among HCV seroconverters identified in a unique community-based cohort. METHODS: Subjects were 106 drug users with documented dates of HCV seroconversion from the Amsterdam Cohort Study...
2011: PloS One
Andrzej Denys
It is 50 years since the first antiviral drug--JUDR for the local herpes keratitis was introduced and over 25 years since HIV/AIDS was isolated and the Noble Prize in Medicine and Physiology was given to its discovers. Now, there are 50 antiviral drugs, in which 25 are for HIV, the others are for herpes virus, shingles, cytomegalovirus, hepatitis virus and influenza A virus. Drugs for hemorrhagic fever Ebola and Marbourg as well as Denga fever are under way In the paper the current knowledge on chemotherapy and prophylaxis is presented in the following viral infections: HIV, HBV, HCV, CMV, HSV, shingles and other...
May 2011: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Xin-Xing Wang, Jing-Xiao Li, Wen-Guang Wang, Xiao-Mei Sun, Chun-Yan He, Jie-Jie Dai
Virological testing and monitoring is a fundamental part of quality control of experimental animals. However, there are few papers regarding the spectrum and status of natural infection in wild tree shrews with human and animal pathogenic viruses. Using enzyme-linked immunosorbent adsorption assay (ELISA), we tested sixty wild tree shrews captured from Qinglong, an outskirt region of Kunming, Yunnan Province, China for eleven viruses, including herpes simplex virus, coxsackie virus, influenza virus, HAV, HBV, HCV, HDV, dengue virus, hemorrhagic fever virus and measles virus...
February 2011: Dong Wu Xue Yan Jiu, Zoological Research
P D Christopoulos, S Katsoudas, A Androulaki, L Nakopoulou, T Economopoulos, D V Vlahakos
A 65-year-old white female patient with normal baseline renal function was referred to our hospital with nonoliguric renal failure requiring hemodialysis after progressive deterioration over the previous 6 months. Her past medical history was remarkable for easy fatigability, weight loss, low-grade fever, hypogammaglobulinemia and mild hepatosplenomegaly manifested over the past 6 years. Several liver and bone marrow biopsies during that period had shown a nonspecific polyclonal T-cell infiltration, and she was administered low-dose steroids for symptomatic relief...
February 2009: Clinical Nephrology
V Gaspari, A D'Antuono, C Misciali
As it is well-known, during secondary syphilis, it is possible to observe a systemic involvement of the treponemal infection. The visceral localizations are rarely observed, and they usually present themselves as asymptomatic or with aspecific symptoms. This report concerns a case of a homosexual patient who referred to us in order to perform blood tests for the main sexually transmitted diseases (HIV, HBV, HCV, TPEIA). Moreover, he reported a history of palmo-plantar erythematous desquamative lesions, spontaneously resolved...
February 2008: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Immaculada Pons, Isabel Sanfeliu, María Mercedes Nogueras, Montserrat Sala, Manuel Cervantes, M José Amengual, Ferran Segura
BACKGROUND: Although the first clinical descriptions of Bartonella infection were associated with immunocompromised patient with bacillary angiomatosis, we currently know that this organism is directly involved in diseases affecting a large number of patients, regardless of their immune status. Cat scratch disease, hepatic peliosis, and some cases of bacteraemia and endocarditis, are directly caused by some species of the genus Bartonella. The purpose of this study was to determinate the prevalence of IgG antibodies against Bartonella henselae and B...
2008: BMC Infectious Diseases
Isa K Mushahwar
In the last 30 years, tremendous progress in identifying transfusion-transmitted viruses such as HBV, HCV, and HIV in industrialized countries has been achieved. Currently, the residual risk of transmitting these viruses through transfusion is very low especially after the introduction of "minipool" nucleic acid-amplification tests. Despite these major technical advances, there remains a legitimate concern as to the transmission of other blood-borne infectious agents through blood transfusion. Among these agents are HBV mutants, occult HBV, and HCV infections, malaria, Chagas, West Nile, dengue, and vesiviruses, bacterial infections such as Yersinia enterocolitica, and tick borne diseases such as human monocytic ehrlichiosis, human granulocytic ehrlichiosis, Rocky Mountain spotted fever, and Lyme and prion diseases such as Creutzfeldt and variant Creutzfeldt...
August 2007: Journal of Medical Virology
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