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https://www.readbyqxmd.com/read/28546668/tale-of-the-tails-the-missing-postpartum-iucd-strings
#1
Sujnanendra Mishra
INTRODUCTION: Using an intrauterine device (IUD) is many times safer than pregnancy and more effective in preventing pregnancy than oral contraceptives, condoms, spermicidal, any barrier method, or natural family planning. Benefits of healthy timing and spacing of pregnancy are many. Postpartum contraception is becoming popular after introduction of PPIUCD services. OBJECTIVE: To study the incidence, management, clinical outcome of missing strings cases in post-placental and intra-cesarean IUCD...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28538285/teenage-pregnancy-prevention-the-role-of-young-men
#2
Gabriela Vargas, Joshua Borus, Brittany M Charlton
PURPOSE OF REVIEW: Although teenage pregnancy is declining in many parts of the world, it remains associated with considerable social, health, and economic outcomes. Pregnancy prevention efforts focus primarily on young women, with minimal attention to young men. This review highlights recent literature pertaining to the role of young men in pregnancy prevention. RECENT FINDINGS: Young men have varying views on contraception as well as which partner(s) should be responsible for its use...
May 22, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28535706/-contraceptive-care-for-adolescents-in-school-based-health-centers-is-essential
#3
Alison Moriarty Daley, E Carol Polifroni
Adolescents often face hurdles that may interfere with accessing contraceptive services. School-based health centers (SBHCs) are available to many teens in the United States; however, only half of SBHCs that serve adolescents are permitted to provide contraception. The aim of this descriptive phenomenological study was to describe the lived experience of nurse practitioners (NPs) providing contraceptive care to teens in SBHCs. Twelve NPs were interviewed and Colaizzi's method of descriptive phenomenological analysis was used to describe the lived experience of NPs providing contraceptive care to adolescents in SBHCs...
January 1, 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/28535045/bet-bromodomain-inhibitors-with-one-step-synthesis-discovered-from-virtual-screen
#4
Alex M Ayoub, Laura M L Hawk, Ryan J Herzig, Jiewei Jiang, Andrea J Wisniewski, Clifford T Gee, Peiliang Zhao, Jin-Yi Zhu, Norbert Berndt, Nana K Offei-Addo, Thomas G Scott, Jun Qi, James E Bradner, Timothy R Ward, Ernst Schönbrunn, Gunda I Georg, William C K Pomerantz
Chemical inhibition of epigenetic regulatory proteins BrdT and Brd4 is emerging as a promising therapeutic strategy in contraception, cancer, and heart disease. We report an easily synthesized dihydropyridopyrmidine pan-BET inhibitor scaffold, which was uncovered via a virtual screen followed by testing in a fluorescence anisotropy assay. Dihydropyridpyimidine 3 was subjected to further characterization and is highly selective for the BET family of bromodomains. Structure-activity relationship data and ligand deconstruction highlight the importance of the substitution of the uracil moiety for potency and selectivity...
May 23, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28524747/health-care-students-at-an-argentinean-school-of-medicine-are-they-well-prepared-to-provide-quality-sexual-and-reproductive-health-services
#5
Belén Provenzano-Castro, Silvia Oizerovich, Babill Stray-Pedersen
OBJECTIVES: The aim of our study was to assess what students of the University of Buenos Aires School of Medicine learn about sexual and reproductive health (SRH) and rights, focusing particularly on their knowledge of accessibility to contraception and abortion legislation. METHODS: In this cross-sectional study, self-administered, anonymous questionnaires were administered to 760 first year students and to 695 final year students from different fields of study (medicine, midwifery, nursing, radiology, nutrition, speech therapy and physiotherapy) between 2011 and 2013...
May 19, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28521061/extracellular-camp-activates-molecular-signalling-pathways-associated-with-sperm-capacitation-in-bovines
#6
Carlos Agustín I Alonso, Claudia E Osycka-Salut, Luciana Castellano, Andreína Cesari, Nicolás Di Siervi, Adrián Mutto, Anders Johannisson, Jane M Morrell, Carlos Davio, Silvina Perez-Martinez
STUDY QUESTION: Is extracellular cAMP involved in the regulation of signalling pathways in bovine sperm capacitation? SUMMARY ANSWER: Extracellular cAMP-induced sperm capacitation through the activation of different signalling pathways that involve phospholipase C (PLC), PKC/ERK1-2 signalling and an increase in sperm Ca2+ levels, as well as soluble AC and cAMP/protein kinase A (PKA) signalling. WHAT IS KNOWN ALREADY: In order to fertilize the oocyte, ejaculated spermatozoa must undergo a series of changes in the female reproductive tract, known as capacitation...
May 18, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28520584/eating-disorders-and-bone-metabolism-in-women
#7
Lauren Robinson, Nadia Micali, Madhusmita Misra
PURPOSE OF REVIEW: Eating Disorders are psychiatric disorders associated with a high risk for low bone mineral density (BMD) and fractures. Low BMD is a consequence of undernutrition, changes in body composition, and hormonal alterations. This review summarizes recent findings regarding novel strategies for assessing bone outcomes in patients with eating disorders, factors contributing to altered bone metabolism, and possible therapeutic strategies. RECENT FINDINGS: Emerging research in this field suggests that not only anorexia nervosa, but also bulimia nervosa results in lower BMD compared to controls...
May 16, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28482329/endometrial-changes-during-ulipristal-acetate-use-a-systematic-review
#8
REVIEW
Inge De Milliano, Dominique Van Hattum, Johannes C F Ket, Judith A F Huirne, Wouter J K Hehenkamp
Ulipristal acetate is increasingly used for several clinical indications, like emergency contraception and pre-treatment of uterine fibroids. It has mixed progesterone agonist and antagonist effects in the myometrium and endometrium. Due to its progesterone antagonistic effect, an unopposed estrogen effect could occur which could cause (pre-)malignant lesions in the endometrium. Several studies have been performed to evaluate this possible increased risk for endometrial malignancies when using ulipristal acetate...
April 28, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28472576/ulipristal-acetate-an-update-for-australian-gps
#9
Danielle Mazza
BACKGROUND: In Australia, use and understanding of emergency contraception among women remains relatively low. This is despite the introduction of levonorgestrel emergency contraceptive pills (ECPs) more than a decade ago. In April 2016, a new ECP with the active ingredient ulipristal acetate became available in Australia. OBJECTIVE: The aims of this article are to increase understanding of the recently introduced ulipristal acetate ECP, including its safety profile, effi-cacy and special considerations; dispel common myths and misconceptions about emergency contraception; and to provide guidance on emergency contraceptive management in general practice, considering the recent advances...
2017: Australian Family Physician
https://www.readbyqxmd.com/read/28442191/barriers-to-single-dose-levonorgestrel-only-emergency-contraception-access-in-retail-pharmacies
#10
Van Mimi Chau, Carol A Stamm, Laura Borgelt, Michelle Gaffaney, Alia Moore, Rachel Z Blumhagen, Leanne Rupp, Daniel Topp, Christine Gilroy
OBJECTIVES: In February 2014, the Food and Drug Administration updated its regulations to make all single-dose levonorgestrel-only emergency contraception (LNG-EC) available over the counter. This study examines the availability and access to LNG-EC shortly after this policy change, and any additional barriers to obtaining LNG-EC in Colorado retail pharmacies. STUDY DESIGN: From June to July 2014, three female interviewers posing as women seeking LNG-EC conducted a telephone survey of all 633 Colorado retail pharmacies listed in The Little Blue Book (2014) phone directory...
April 23, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28419700/pregnancy-ambivalence-and-long-acting-reversible-contraceptive-larc-use-among-young-adult-women-a-qualitative-study
#11
Jenny A Higgins
CONTEXT: Many young adults are unclear about how much they want to have, or prevent having, a baby. However, pregnancy ambivalence is an underexamined factor in the uptake of long-acting reversible contraceptive (LARC) methods-IUDs and implants-the most effective methods available. METHODS: In 2014, investigators conducted six focus groups and 12 interviews with 50 women aged 18-29 in Dane County, Wisconsin; participants were either university students or community residents receiving public assistance...
April 17, 2017: Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28416014/contraceptive-service-provider-imposed-restrictions-to-contraceptive-access-in-urban-nigeria
#12
Hilary M Schwandt, Ilene S Speizer, Meghan Corroon
BACKGROUND: Health service providers can restrict access to contraceptives through their own imposed biases about method appropriateness. In this study, provider biases toward contraceptive service provision among urban Nigerian providers was assessed. METHODS: Health providers working in health facilities, as well as pharmacists and patent medical vendors (PMV), in Abuja, Benin City, Ibadan, Ilorin, Kaduna, and Zaria, were surveyed in 2011 concerning their self-reported biases in service provision based on age, parity, and marital status...
April 17, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28410124/wildlife-population-management-are-contraceptive-vaccines-a-feasible-proposition
#13
Satish Kumar Gupta, Vidisha Minhas
To minimize human-animal conflicts for habitation and burden of zoonotic diseases, it is imperative to develop new strategies for wildlife population management. In this direction, contraceptive vaccines eliciting immune response against hormones/proteins critical for reproduction have emerged as one of the promising options. Contraceptive vaccines based on neutralization of gonadotropin releasing hormone (GnRH) have been used for inhibition of fertility in various species such as wild horses, white-tailed deer, pigs, cats, dogs etc...
June 1, 2017: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/28403923/high-abortion-rate-in-martinique-f-w-i-in-spite-of-a-large-contraceptive-availability-what-are-the-determinants
#14
L Vergnaud, J-L Volumenie, C Bonnier
INTRODUCTION: Despite a similar health insurance coverage and access to contraception, Martinique F.W.I. has a higher rate of abortion than continental France (25.6 versus 15.3 per thousand respectively). The reasons are still largely unknown. A different contraceptive pattern, a lower use of emergency contraception in Martinique may be involved. We sought to explore the contraceptive pattern, to evaluate the use of emergency contraception and the reasons leading to an unwanted pregnancy among women seeking for an abortion...
March 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28403858/contraceptive-service-provider-imposed-restrictions-to-contraceptive-access-in-urban-nigeria
#15
Hilary M Schwandt, Ilene S Speizer, Meghan Corroon
BACKGROUND: Health service providers can restrict access to contraceptives through their own imposed biases about method appropriateness. In this study, provider biases toward contraceptive service provision among urban Nigerian providers was assessed. METHODS: Health providers working in health facilities, as well as pharmacists and patent medical vendors (PMV), in Abuja, Benin City, Ibadan, Ilorin, Kaduna, and Zaria, were surveyed in 2011 concerning their self-reported biases in service provision based on age, parity, and marital status...
April 12, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28397132/modifiable-environmental-factors-in-inflammatory-bowel-disease
#16
REVIEW
Kristin E Burke, Christine Boumitri, Ashwin N Ananthakrishnan
PURPOSE OF REVIEW: Environmental factors may influence predisposition to develop inflammatory bowel diseases (Crohn's disease, ulcerative colitis) or alter its natural history by modification of both the host immune response and intestinal microbial composition. The purpose of this review is to translate such evidence into clinical practice by a focus on interventional studies that have modified such environmental influences to improve disease outcomes. RECENT FINDINGS: Several environmental influences have been identified in the recent literature including tobacco use, diet, antibiotics, vitamin D deficiency, stress, appendectomy, and oral contraceptive use...
May 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28395681/contraception-coverage-and-methods-used-among-women-in-south-africa-a-national-household-survey
#17
M F Chersich, N Wabiri, K Risher, O Shisana, D Celentano, T Rehle, M Evans, H Rees
BACKGROUND: Globally, family planning services are being strengthened and the range of contraceptive choices expanded. Data on contraceptive coverage and service gaps could help to shape these initiatives. OBJECTIVE: To assess contraception coverage in South Africa (SA) and identify underserved populations and aspects of programming that require strengthening. METHODS: Data from a 2012 SA household survey assessed contraception coverage among 6 296 women aged 15 - 49 years and identified underserved populations...
March 29, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28388997/barriers-to-health-care-providers-provision-of-long-acting-reversible-contraception-to-adolescent-and-nulliparous-young-women
#18
Brooke Hopkins
Despite recommendations for long-acting reversible contraception (LARC) as a first-line contraceptive method for adolescents and young women, its use in the United States remains low. This integrative review highlights previously unidentified barriers to health care providers' provision of LARC to adolescent and nulliparous young women. Four themes emerged: Appropriateness of Candidates and Contraceptive Safety, Provider Training and Work Setting, Appropriate Resources, and Opportunity. Raising awareness of barriers to LARC use may galvanize providers to find solutions...
April 2017: Nursing for Women's Health
https://www.readbyqxmd.com/read/28385554/a-survey-regarding-acceptability-of-oral-emergency-contraception-according-to-the-posited-mechanism-of-action
#19
S J Willetts, M MacDougall, S T Cameron
OBJECTIVE: The objective was to determine the acceptability to women of oral emergency contraception (EC) that works by inhibiting ovulation, preventing implantation or disrupting implantation, and also to determine the characteristics of women associated with the acceptability of each posited mechanism of action. STUDY DESIGN: Women completed a self-administered, anonymous questionnaire asking whether they would consider using an EC pill based on each of three hypothetical mechanisms of action: inhibiting ovulation, preventing implantation or disrupting implantation...
April 3, 2017: Contraception
https://www.readbyqxmd.com/read/28383622/the-conscientious-objection-debate-on-emergency-contraception
#20
G Montanari Vergallo, S Zaami, N M Di Luca, E Marinelli
The authors discuss the emergency contraception (EC) topic, assessing scientific and ethical aspects. The almost totality of the studies carried out tends to report on the use of drugs as an emergency measure to prevent pregnancy. However, it is not yet completely excluded that emergency contraceptives can induce medical abortion. The debate on side effects of EC continues to be a highly emotional and controversial issue both for advocates who believe they will lower considerably the number of unintended pregnancies and abortions, and for opponents who believe that using emergency contraception amounts to an abortion...
March 2017: La Clinica Terapeutica
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