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https://www.readbyqxmd.com/read/28806400/changes-in-the-anterior-segment-after-cycloplegia-with-a-biometer-using-swept-source-optical-coherence-tomography
#1
Tomoaki Higashiyama, Maki Iwasa, Masahito Ohji
The aim of this study was to investigate changes in the anterior segment of the eye after cycloplegia. A biometer combined with swept-source optical coherence tomography (SSOCT) was used for measurements. Patients with strabismus or amblyopia who underwent cycloplegia were included. The axial length, central corneal thickness, anterior chamber depth, and lens thickness were measured with the biometer-SSOCT system before and after cycloplegia. Altogether, 10 eyes of 10 patients (mean age 7.20 ± 3.08 years, range 4-14 years) were evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/28798362/a-large-family-with-inherited-optic-disc-anomalies-a-correlation-between-a-new-genetic-locus-and-complex-ocular-phenotypes
#2
Decai Wang, Xinyuan Pan, Jiangdong Ji, Shun Gu, Xiantao Sun, Chao Jiang, Weiyi Xia, Zhihua Qiu, Xiaoli Kang, Sijia Ding, Qinghuai Liu, Xue Chen, Fang Lu, Chen Zhao
Congenital cavitary optic disc anomalies (CODA) is clinically typified by an enlarged excavation of optic disc in diverse degrees. Here, we report the clinical and genetic findings in a four-generation Chinese family with a complicated form of autosomal dominant CODA. Cardinal manifestations included bilateral excavated optic disc with multiple cilioretinal vessels emerging and bilateral retinoschisis with great variability in the range of extension and severity. Other intra-familial phenotypic diversities were also noted, including severity in retinal atrophy, onset age of visual impairment and presence of congenital nystagmus and strabismus...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28796570/pedigree-analysis-of-familial-primary-concomitant-horizontal-strabismus-in-northern-india
#3
Zia Chaudhuri, Jibin John, Satinder Aneja, B K Thelma
PURPOSE: Familial clustering of common forms of primary strabismus like esotropia (ET) and exotropia (XT) is observed in a proportion of the strabismus cohort. The genetic components of this remain unidentified. Linkage studies have demonstrated susceptibility locus for primary strabismus at the STBMS1 locus on 7p22.1 as well as other loci on 4q28.3 and 7q31.2. Recently next generation sequencing (NGS) technology has emerged as a powerful tool in discovery genomics and a large number of novel disease-causing variants are being reported...
August 10, 2017: Strabismus
https://www.readbyqxmd.com/read/28791063/the-effect-of-sub-tenon-s-bupivacaine-on-oculocardiac-reflex-during-strabismus-surgery-and-postoperative-pain-a-randomized-clinical-trial
#4
Mohammad Reza Talebnejad, Saeed Khademi, Milad Ghani, Mohammad Reza Khalili, Mohammad Hossein Nowroozzadeh
PURPOSE: Oculocardiac reflex (OCR), defined as bradycardia induced by manipulation of extraocular muscles, is a serious complication during strabismus surgery for which prevention and proper management is required. In the present study, we investigated the efficacy of sub-Tenon injection of bupivacaine for prevention of OCR and postoperative pain. METHODS: A prospective randomized controlled clinical trial was conducted. Fifty patients who were candidates for strabismus surgery were randomized into case (sub-Tenon's bupivacaine injection) or control (normal saline injection) groups...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28774524/clinical-profiles-and-surgical-outcomes-of-adult-esotropia
#5
Mikel Mikhail, Michael Flanders
OBJECTIVE: The aim of this study was to describe the clinical features and surgical outcomes of teenage and adult patients with esotropia undergoing strabismus surgery with adjustable sutures. METHODS: Seventy-three patients were included in this retrospective, cohort study. Patients were stratified into group 1 (35 with childhood-onset esotropia [CET]) and group 2 (38 with adult-onset esophoria-tropia [EPT]). Preoperative immediate, 2-week, and 4-6-month postoperative measurements of ocular alignment, as well as fusional testing, were performed...
August 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28771056/ocular-motor-function-in-children-with-spastic-hemiplegia-evaluated-by-the-ocular-motor-score
#6
A Rydberg, J Ygge, M Olsson
PURPOSE: To assess the ocular motor functions in children with spastic hemiplegia by using the Ocular Motor Score (OMS). MATERIAL: This study included 34 children, median age 11 years. The children were divided into 3 groups according to the underlying brain lesion; group 1 malformations, group 2 white matter damage of immaturity (WMDI), and group 3 cortical/subcortical lesions. METHODS: The OMS protocol consists of 15 different subtests evaluating ocular motor functions...
August 3, 2017: Strabismus
https://www.readbyqxmd.com/read/28757706/myopic-strabismus-fixus-with-endophthalmitis
#7
Taoufik Abdellaoui, Yassine Abaloune, Redouane Messaoudi, Fouad Elasri, Karim Reda, Abdelbarre Oubaaz
No abstract text is available yet for this article.
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28757690/prognostic-preoperative-factors-for-successful-outcome-of-surgery-in-horizontal-strabismus
#8
Namita Kumari, Abadan Khan Amitava, Mohammad Ashraf, Shivani Grover, Ashiya Khan, Prabha Sonwani
CONTEXT: Surgery for horizontal strabismus reportedly has a success rate of 60%-80%. However, which preoperative factors are predictive of this success is not clear. AIMS: To identify prognostic factors those are predictive of successful outcome in horizontal strabismus surgery. SETTINGS AND DESIGN: Observational analytical study using multiple logistic regression (MLR). SUBJECTS AND METHODS: We assessed the medical records of patients who had undergone first-time horizontal muscle strabismus surgery between 2002 and 2013, where complete follow-up data were available for ≥6 weeks, and also, we collected data prospectively on patients operated between January 2014 and September 2015...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28756763/the-effect-of-omitting-an-early-population-based-vision-screen-in-the-netherlands-a-micro-simulation-model-approach
#9
F Sloot, Eam Heijnsdijk, J H Groenewoud, F Goudsmit, E W Steyerberg, H J de Koning, H J Simonsz
Objective To estimate the effect of omitting an individual screen from a child vision screening programme on the detection of amblyopia in the Netherlands. A previous study (Rotterdam Amblyopia Screening Effectiveness Study) suggested that the three screens carried out between 6 and 24 months contributed little. Methods We developed a micro-simulation model that approximated the birth-cohort data from the previous study, in which 2964 children had completed follow-up at age 7, and 100 amblyopia cases were detected...
September 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28753217/retrospective-study-of-visual-outcomes-and-complications-after-sutureless-flapless-and-glueless-intrascleral-fixation-of-posterior-chamber-intraocular-lens-in-children-and-young-adults
#10
V Rajesh Prabu, Smita Kapoor, Swarna Udayakumar, Priyanka Gupta
PURPOSE: To evaluate the visual outcomes and complications after sutureless, flapless, and glueless intrascleral fixation of a posterior chamber intraocular lens (IOL) in patients between the ages of 5 and 20 years. METHODS: Children with gross subluxated lenses and aphakia following intracapsular cataract extraction with inadequate posterior capsular support underwent intrascleral fixation of a standard three-piece posterior chamber IOL without sutures, flaps, or glue...
July 28, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28753216/strabismus-after-ocular-surgery
#11
Ethan K Sobol, Jamie B Rosenberg
Many types of ocular surgery can cause diplopia, including eyelid, conjunctival, cataract, refractive, glaucoma, retinal, and orbital surgery. Mechanisms include direct injury to the extraocular muscles from surgery or anesthesia, scarring of the muscle complex and/or conjunctiva, alteration of the muscle pulley system, mass effects from implants, and muscle displacement. Diplopia can also result from a loss of fusion secondary to long-standing poor vision in one eye or from a decompensation of preexisting strabismus that was not recognized preoperatively...
July 28, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28749958/the-impact-of-facial-abnormalities-and-their-spatial-position-on-perception-of-cuteness-and-attractiveness-of-infant-faces
#12
Jennifer Lewis, Debi Roberson, Tom Foulsham
Research has demonstrated that how "cute" an infant is perceived to be has consequences for caregiving. Infants with facial abnormalities receive lower ratings of cuteness, but relatively little is known about how different abnormalities and their location affect these aesthetic judgements. The objective of the current study was to compare the impact of different abnormalities on the perception of infant faces, while controlling for infant identity. In two experiments, adult participants gave ratings of cuteness and attractiveness in response to face images that had been edited to introduce common facial abnormalities...
2017: PloS One
https://www.readbyqxmd.com/read/28744253/novel-eye-movement-disorders-in-whipple-s-disease-staircase-horizontal-saccades-gaze-evoked-nystagmus-and-esotropia
#13
Aasef G Shaikh, Fatema F Ghasia
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation. We describe a unique patient with the central nervous system Whipple's disease who had typical features, including parkinsonism, cognitive impairment, and up-gaze limitation; but also had diplopia, esotropia with mild horizontal (abduction more than adduction) limitation, and vertigo...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28743725/altered-balance-of-receptive-field-excitation-and-suppression-in-visual-cortex-of-amblyopic-macaque-monkeys
#14
Luke E Hallum, Christopher Shooner, Romesh D Kumbhani, Jenna G Kelly, Virginia García-Marín, Najib J Majaj, J Anthony Movshon, Lynne Kiorpes
In amblyopia, a visual disorder caused by abnormal visual experience during development, the amblyopic eye loses visual sensitivity while the other (fellow) eye is largely unaffected. Binocular vision in amblyopes is often disrupted by interocular suppression. We used 96-electrode arrays to record neurons and neuronal groups in areas V1 and V2 of 6 female monkeys (Macaca nemestrina) made amblyopic by artificial strabismus or anisometropia in early life, as well as 2 visually normal female monkeys (Macaca nemestrina)...
July 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28743414/strabismus-associated-myopia-review
#15
P Hernández Martínez, J M Rodríguez Del Valle
INTRODUCTION: The treatment of strabismus associated with myopia is often a therapeutic challenge for the ophthalmologist. The strabismus associated with myopia has certain peculiarities and there are even certain types of strabismus that occur exclusively in myopia, such as strabismus fixus, requiring treatments with specific surgical techniques. MATERIALS AND METHODS: It is important to make a correct differential diagnosis, because there are many conditions described with this association...
July 23, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28742638/extraocular-muscle-findings-in-myasthenia-gravis-associated-treatment-resistant-ophthalmoplegia-a-case-report
#16
Robyn M Rautenbach, Komala Pillay, Anthony D N Murray, Jeannine M Heckmann
We report the histopathological and ultrastructural tissue analysis of extraocular muscle (EOM) obtained from a patient with seronegative myasthenia gravis (MG) with treatment-resistant ophthalmoplegia for 3.5 years. The EOM demonstrated predominantly myopathic features and ultrastructural evidence of mitochondrial dysfunction, but the most striking features were increased endomysial collagen and adipocyte replacement of muscle fibers. By contrast, control EOM from a patient undergoing strabismus surgery for a sensory exotropia in a nonseeing eye and a similar duration of deviation, showed normal muscle histology...
July 24, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28741406/balanced-endoscopic-medial-and-transcutaneous-lateral-orbital-decompression-in-graves-orbitopathy
#17
Estefanía Hernández-García, J Javier San-Román, Ramón González, Araceli Nogueira, Ignacio Genol, Bazil Stoica, Nicolás Toledano, Guillermo Plaza
BACKGROUND: To determine the clinical outcomes and morbidity of endoscopic medial wall combined with transcutaneous lateral orbital wall decompression in Graves' orbitopathy. METHODOLOGY: A retrospective noncomparative case series of patients who underwent surgical decompression for Graves' orbitopathy at Hospital Universitario de Fuenlabrada between 2004 and 2014 was performed. We reviewed the patients' charts and analyzed before and after the decompression, the visual acuity (Snellen chart), optic nerve compression (fundoscopy and optic coherence tomography), exophthalmometry (Hertel measurement), ocular motility, diplopia, eyelid surgery needed after decompression and its possible complications...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28734813/incidence-and-types-of-pediatric-nystagmus
#18
David L Nash, Nancy N Diehl, Brian G Mohney
PURPOSE: To report the incidence, prevalent subtypes and clinical characteristics of pediatric nystagmus diagnosed over a 30-year period. DESIGN: Retrospective, population-based study METHODS: Using the Rochester Epidemiology Project, the medical records of all children (<19 years) diagnosed as residents in Olmsted County, Minnesota with any form of nystagmus from January 1, 1976, through December 31, 2005, were reviewed. RESULTS: Seventy-one children were diagnosed during the 30-year period, yielding an annual incidence of 6...
July 19, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28733711/a-brief-history-of-neurological-botulinum-toxin-therapy-in-germany
#19
REVIEW
Dirk Dressler, Peter Roggenkaemper
Botulinum toxin (BT) has long been infamous in food safety and biological warfare. In the early 1970s, Alan B Scott of San Francisco invented its therapeutic use originally in extraocular eye muscles to treat strabismus using a therapeutic BT type A preparation provided by Edward J Schantz and Eric A Johnson. Subsequently a large number of medical indications based on motor and glandular hyperactivity and-most recently-chronic migraine are now treated by BT therapy. BT's highly specific and elaborate mechanism of action represents a completely novel therapeutic principle which will have consequences far beyond existing indications...
July 21, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28733687/an-ecologic-study-of-trends-in-the-prevalence-of-myopia-in-chinese-adults-in-singapore-born-from-the-1920s-to-1980s
#20
Sonoko Sensaki, Charumathi Sabanayagam, Pavan K Verkicharla, Adeola Awodele, Kok Hian Tan, Audrey Chia, Seang Mei Saw
INTRODUCTION: This study aimed to investigate secular trends in the prevalence of myopia over 6 decades (from the 1920s to 1980s) in Chinese adults in Singapore. MATERIALS AND METHODS: Parental myopia prevalence was estimated using a parent-completed questionnaire in paediatric cohorts that included: 1) The Singapore Cohort Of Risk factors for Myopia (SCORM), 2) The Strabismus, Amblyopia and Refractive Error in Singaporean Children (STARS), and 3) The Growing Up in Singapore Towards healthy Outcomes (GUSTO)...
June 2017: Annals of the Academy of Medicine, Singapore
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