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https://www.readbyqxmd.com/read/28220267/chimpanzee-down-syndrome-a-case-study-of-trisomy-22-in-a-captive-chimpanzee
#1
Satoshi Hirata, Hirohisa Hirai, Etsuko Nogami, Naruki Morimura, Toshifumi Udono
We report a case of chimpanzee trisomy 22 in a captive-born female. Because chromosome 22 in great apes is homologous to human chromosome 21, the present case is analogous to human trisomy 21, also called Down syndrome. The chimpanzee in the present case experienced retarded growth; infantile cataract and vision problems, including nystagmus, strabismus, and keratoconus; congenital atrial septal defect; and hypodontia. All of these symptoms are common in human Down syndrome. This case was the second reported case of trisomy 22 in the chimpanzee...
February 21, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28220248/-prism-adaptation-test-before-strabismus-surgery-results-of-a-survey-and-literature-review
#2
U Pichler, M Rohleder, O Ehrt
BACKGROUND: Variable preoperative deviations and compensatory mechanisms may cause wrong dosage of strabismus surgery and result in over- or undercorrection. A long-lasting prism adaptation test (PAT) before surgery is supposed to reduce those difficulties and to improve the postoperative results. To date, the use of prism adaptation before surgery has not been systematically examined. METHODS: A total of 15 strabismologists and 28 orthoptists in Austria were interviewed about their approach to prism adaptation in 9 types of strabismus...
February 20, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28217058/sub-tenon-s-injection-versus-paracetamol-in-pediatric-strabismus-surgery
#3
A N Ibrahim, T Shabana
BACKGROUND: Emergence agitation, vomiting, and oculocardiac reflex (OCR) in children undergoing strabismus surgery under general anesthesia are common problems. The purpose of this study was to determine whether the effect of analgesia can reduce the incidence of these problems. We compared the effects of sub-Tenon's injection versus intravenous (IV) and rectal paracetamol in this surgery. METHODS: In a prospective, randomized, double-blind study, ninety patients ranging in age from 4 to 8 years scheduled for extraocular muscle surgery for strabismus were included in this study...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28217057/comparison-of-topical-oxybuprocaine-and-intravenous-fentanyl-in-pediatric-strabismus-surgery
#4
Ibrahim Yousafzai, Abdul Zahoor, Butrov Andrey, Nauman Ahmad
PURPOSE: To compare the outcomes such as postoperative nausea/vomiting, analgesic requirements, and hospital stay following the use of topical oxybuprocaine hydrochloride 0.4% or intravenous (IV) fentanyl in children undergoing strabismus surgery. METHODS: This was a prospective cohort study. Children operated under general anesthesia for strabismus were given topical oxybuprocaine hydrochloride 0.4% (Group T) and IV fentanyl (Group F) before surgery. The episodes of nausea/vomiting, pain score, requirement of additional analgesia during postoperative period, and duration of hospital stay were compared in two groups...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28212157/current-approaches-to-myopia-control
#5
Seo Wei Leo
PURPOSE OF REVIEW: Myopia is a global problem, being particularly prevalent in the urban areas of east and southeast Asia. In addition to the direct economic and social burdens, associated ocular complications may lead to substantial vision loss. With prevalence of myopia above 80% and high myopia over 20%, it is crucial to control myopia. The aim of this review to is provide an update on the interventions to slow the onset of myopia and retard its progression. RECENT FINDINGS: The epidemic of myopia is characterized by increasingly early onset, combined with high myopia progression rates...
February 15, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28210544/cataracts-and-strabismus-associated-with-hand-rearing-using-artificial-milk-formulas-in-bengal-tiger-panthera-tigris-spp-tigris-cubs
#6
Rogério Ribas Lange, Leandro Lima, Erika Frühvald, Vera Sônia Nunes da Silva, Aparecida Sônia de Souza, Fabiano Montiani-Ferreira
The aim of this investigation is to describe the potential contributing nutritional factors involved in the development of ophthalmic and dermatologic changes in four Bengal tiger (Panthera tigris spp tigris) cubs fed an artificial milk formula. The affected animals were compared with two other tiger cubs that had been nursed by their dam naturally. After the first clinical signs appeared, the tiger cubs underwent ophthalmic evaluation. Severe symmetric generalized alopecia over the trunk, sparing the head and distal portion of the front and rear limbs, bilateral cataracts and strabismus were noticed...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28196268/three-cases-of-exotropic-moebius-syndrome
#7
Abbas Bagheri, Mohaddese Feizi
Moebius syndrome is characterized by congenital facial palsy and limitation in horizontal gaze. The surgical results of the exotropic pattern are rare and have not been published before. The authors report three cases of exotropic Moebius syndrome. Maximal weakening of the lateral rectus muscles followed by strengthening of the medial recti in exotropic Moebius syndrome can improve exotropia significantly. Most of these cases also need some measures to relieve the often associated severe dry eye. [J Pediatr Ophthalmol Strabismus...
February 14, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28196267/detection-of-minimally-visible-recurrent-retinoblastoma-by-hand-held-spectral-domain-optical-coherence-tomography
#8
Maria E Gonzalez-Montpetit, Wasim A Samara, George N Magrath, Carol L Shields
A 2-month-old male infant with bilateral familial retinoblastoma was treated with intravenous chemotherapy and focal adjuvant therapy. At 5 months of follow-up, fundus examination and ultrasonography disclosed no recurrence; however, hand-held spectral-domain optical coherence tomography (SD-OCT) demonstrated subclinical recurrence within a previous regression scar. Subsequent treatment led to flat scar. Hand-held SD-OCT can be a useful tool for detection of subclinical recurrent retinoblastoma. [J Pediatr Ophthalmol Strabismus...
February 14, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28196266/four-dimensional-microscope-integrated-optical-coherence-tomography-to-visualize-suture-depth-in-strabismus-surgery
#9
Neel D Pasricha, Paramjit K Bhullar, Christine Shieh, Oscar M Carrasco-Zevallos, Brenton Keller, Joseph A Izatt, Cynthia A Toth, Sharon F Freedman, Anthony N Kuo
The authors report the use of swept-source microscope-integrated optical coherence tomography (SS-MIOCT), capable of live four-dimensional (three-dimensional across time) intraoperative imaging, to directly visualize suture depth during lateral rectus resection. Key surgical steps visualized in this report included needle depth during partial and full-thickness muscle passes along with scleral passes. [J Pediatr Ophthalmol Strabismus. 2017;54:e1-e5.].
February 14, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28191347/refractive-changes-induced-by-strabismus-corrective-surgery-in-adults
#10
Daphna Mezad-Koursh, Ari Leshno, Tomer Ziv-Baran, Chaim Stolovitch
Purpose. To investigate refractive changes after strabismus correction procedures among adults. Methods. Retrospective chart review of adult patients who had horizontal recti muscles surgery with preoperative and postoperative cycloplegic refraction measurements. The preoperative refraction was mathematically subtracted from the postoperative refraction, and the induced refractive changes were statistically analyzed. Vector analysis was used to examine the magnitude of the toric change. The proportion of clinically significant refractive change was evaluated as well...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28188939/survey-of-nerve-fiber-layer-thickness-in-anisometropic-and-strabismic-amblyopia
#11
Reza Soltani Moghaddam, Abdolreza Medghalchi, Yousef Alizadeh
. To investigate the effect of anisometropic and strabismic amblyopia on the nerve fiber layer thickness. This cross-sectional study was done on 54 amblyopic subjects, equally in both strabismic and anisometropic groups. The thickness otonerve fiber layer measured in superior, inferior, nasal, temporal quadrants and as a whole in both eyes of both groups. The means of thickness were compared in amblyopic and sound eyes. In strabismus group, the average nerve fiber layer thickness of the sound eye , in superior, inferior, nasal and temporal quadrants and as a whole were 113...
January 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28186599/-diagnosis-of-a-case-with-oculocutaneous-albinism-type-%C3%A2-with-next-generation-exome-capture-sequencing
#12
Yuqiang Lyu, Jing Huang, Kaihui Zhang, Guohua Liu, Min Gao, Zhongtao Gai, Yi Liu
OBJECTIVE: To explore the clinical and genetic features of a Chinese boy with oculocutaneous albinism. METHODS: The clinical features of the patient were analyzed. The DNA of the patient and his parents was extracted and sequenced by next generation exome capture sequencing. The nature and impact of detected mutation were predicted and validated. RESULTS: The child has displayed strabismus, poor vision, nystagmus and brown hair. DNA sequencing showed that the patient has carried compound heterozygous mutations of the TYRP1 gene, namely c...
February 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28182149/anterior-segment-ischemia-after-strabismus-surgery
#13
Emine Seyhan Göçmen, Yonca Atalay, Özlem Evren Kemer, Hikmet Yavuz Sarıkatipoğlu
A 46-year-old male patient was referred to our clinic with complaints of diplopia and esotropia in his right eye that developed after a car accident. The patient had right esotropia in primary position and abduction of the right eye was totally limited. Primary deviation was over 40 prism diopters at near and distance. The patient was diagnosed with sixth nerve palsy and 18 months after trauma, he underwent right medial rectus muscle recession. Ten months after the first operation, full-thickness tendon transposition of the superior and inferior rectus muscles (with Foster suture) was performed...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28166429/comparison-of-rating-scales-in-the-development-of-patient-reported-outcome-measures-for-children-with-eye-disorders
#14
Sarah R Hatt, David A Leske, Suzanne M Wernimont, Eileen E Birch, Jonathan M Holmes
BACKGROUND: A rating scale is a critical component of patient-reported outcome instrument design, but the optimal rating scale format for pediatric use has not been investigated. We compared rating scale performance when administering potential questionnaire items to children with eye disorders and their parents. METHODS: Three commonly used rating scales were evaluated: frequency (never, sometimes, often, always), severity (not at all, a little, some, a lot), and difficulty (not difficult, a little difficult, difficult, very difficult)...
February 6, 2017: Strabismus
https://www.readbyqxmd.com/read/28166317/effects-of-reduced-acuity-and-stereo-acuity-on-saccades-and-reaching-movements-in-adults-with-amblyopia-and-strabismus
#15
Ewa Niechwiej-Szwedo, Herbert C Goltz, Linda Colpa, Manokaraananthan Chandrakumar, Agnes M F Wong
Purpose: Our previous work has shown that amblyopia disrupts the planning and execution of visually-guided saccadic and reaching movements. We investigated the association between the clinical features of amblyopia and aspects of visuomotor behavior that are disrupted by amblyopia. Methods: A total of 55 adults with amblyopia (22 anisometropic, 18 strabismic, 15 mixed mechanism), 14 adults with strabismus without amblyopia, and 22 visually-normal control participants completed a visuomotor task while their eye and hand movements were recorded...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28163119/accuracy-of-optical-coherence-tomography-measurements-of-rectus-muscle-insertions-in-adult-patients-undergoing-strabismus-surgery
#16
Julia D Rossetto, Kara M Cavuoto, Norma Allemann, Craig A McKeown, Hilda Capo
PURPOSE: To assess the accuracy of anterior segment optical coherence tomography (AS-OCT) in measuring the distance of extraocular muscle (EOM) insertion to the limbus to improve preoperative assessment of adult patients undergoing strabismus surgery. DESIGN: Reliability analysis. SETTING: An institutional practice. PATIENT POPULATION: 74 adult patients scheduled for strabismus surgery on rectus muscles. OBSERVATION PROCEDURE: The distance between the EOM insertion and the limbus was measured preoperatively with AS-OCT...
February 2, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28161340/evaluating-the-impact-of-strabismus-surgery-on-the-association-of-musculoskeletal-injuries-fractures-and-falls-with-disorders-of-binocular-vision-in-medicare-beneficiaries
#17
Stacy L Pineles, Michael X Repka, Fei Yu, Flora Lum, Anne L Coleman
Disorders of binocular vision that are increasingly prevalent among aged, fee-for-service Medicare beneficiaries are associated with fractures, falls, and musculoskeletal injuries. We evaluate whether strabismus surgery influences the association of injuries in elderly patients with disorders of binocular vision in a 5% random sample of Medicare fee-for-service claims data from 2010 to 2013. There were 22,237 Medicare beneficiaries with a claim that included a diagnosis of a disorder of binocular vision. Of these, the majority had strabismus (49...
February 1, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28159584/botulinum-toxin-in-the-management-of-head-and-neck-disorders
#18
REVIEW
Ravleen Nagi, Deepa Jatti Patil, Shashikant Sahu, Supreet Jain, Giridhar S Naidu
Botulinum toxin is a polypeptide protoxin synthesized by Clostridium botulinum that results in localized reduction of muscle activity by inhibiting acetylcholine release at the neuromuscular junction. In 2004, the US Food and Drug Administration approved its application in the treatment of various medical conditions, such as facial wrinkles, strabismus, cervical dystonia, blepharospasm, and hyperhidrosis. Later, its application extended to improving dental esthetics and gummy smile. It was found to be a safe and effective alternative to medical therapy to treat various head and neck disorders that have a neurologic component...
December 7, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28157223/novel-variants-in-pax6-gene-caused-congenital-aniridia-in-two-chinese-families
#19
R Zhang, S Linpeng, X Wei, H Li, Y Huang, J Guo, Q Wu, D Liang, L Wu
PurposeTo reveal the underlying genetic defect in two four-generation Chinese families with aniridia and explore the pathologic mechanism.MethodsFull ophthalmic examinations were performed in two families with aniridia. The PAX6 gene was directly sequenced in patients of two families, and the detected variants were screened in unaffected family members and two hundred unrelated healthy controls. Real-time quantitative PCR was used to explore pathologic mechanisms of the two variants.ResultsAniridia, cataract, and oscillatory nystagmus were observed in patients of the two families...
February 3, 2017: Eye
https://www.readbyqxmd.com/read/28149143/comparison-of-the-safety-and-efficacy-of-loteprednol-etabonate-0-5-tobramycin-0-3-with-dexamethasone-0-1-tobramycin-0-3-following-strabismus-surgery
#20
İlknur Akyol Salman
OBJECTIVE: To compare the anti-inflammatory efficacy and safety of 0.5% loteprednol etabonate/0.3% tobramycin (LE/T) and 0.1% dexamethasone/0.3% tobramycin (DM/T) ophthalmic suspensions following strabismus surgery. MATERIALS AND METHODS: The records of 40 patients who were treated with either LE/T or DM/T following strabismus surgery were retrospectively reviewed. The recorded signs and symptoms of inflammation and intraocular pressure of the patients at 1 day, 1 week, and 3 weeks after the surgery were evaluated and compared between the groups...
October 2016: Eurasian Journal of Medicine
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