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https://www.readbyqxmd.com/read/28350678/ocular-morbidity-in-the-correction-of-orbital-hypertelorism-and-dystopia-a-15-year-experience
#1
Graeme E Glass, Kate A V Hon, Kemmy Schweibert, Richard Bowman, Barry M Jones, David J Dunaway, Jonathan A Britto
BACKGROUND: Complex surgery for appearance change is controversial. Correction of orbital hypertelorism risks diplopia and loss of stereopsis for aesthetic gain. The risk-to-benefit ratio remains ill-defined. The aim of this study was to define specific ocular morbidity following orbital translocation. METHODS: The authors compared stable preoperative and postoperative orthoptic indices (i.e., angle of strabismus, ocular motility, and acuity) for 23 consecutive patients who underwent orbital translocation between 2000 and 2015 and noted the requirement for corrective surgery...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28346224/mutant-%C3%AE-2-chimaerin-signals-via-bidirectional-ephrin-pathways-in-duane-retraction-syndrome
#2
Alicia A Nugent, Jong G Park, Yan Wei, Alan P Tenney, Nicole M Gilette, Michelle M DeLisle, Wai-Man Chan, Long Cheng, Elizabeth C Engle
Duane retraction syndrome (DRS) is the most common form of congenital paralytic strabismus in humans and can result from α2-chimaerin (CHN1) missense mutations. We report a knockin α2-chimaerin mouse (Chn1KI/KI) that models DRS. Whole embryo imaging of Chn1KI/KI mice revealed stalled abducens nerve growth and selective trochlear and first cervical spinal nerve guidance abnormalities. Stalled abducens nerve bundles did not reach the orbit, resulting in secondary aberrant misinnervation of the lateral rectus muscle by the oculomotor nerve...
March 27, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28345573/clinical-correlation-of-imaging-findings-in-congenital-cranial-dysinnervation-disorders-involving-abducens-nerve
#3
Chanchal Gupta, Pradeep Sharma, Rohit Saxena, Ajay Garg, Sanjay Sharma
PURPOSE: High-resolution magnetic resonance imaging (MRI) of intracranial parts of sixth nerve and seventh nerve and the extraocular muscles (EOMs) in orbit to correlate the clinical characteristics in patients with two special forms of strabismus in congenital cranial dysinnervation disorders which are Duane's retraction syndrome (DRS) and Mobius syndrome. MATERIALS AND METHODS: Morphological analysis by 3T MRI of orbit (using surface coils) and brain (using 32 channel head coil) was performed on 6 patients with clinical DRS (1 bilateral), 2 cases with Mobius syndrome, and 1 case with congenital sixth nerve palsy...
February 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28345241/the-new-swedish-report-on-shaken-baby-syndrome-is-misleading
#4
Kerstin Hellgren, Ann Hellström, Anna-Lena Hård, Lena Jacobson, Ulrika Lidén, Stefan Löfgren, Kristina Teär Fahnehjelm, Jan Ygge
In this issue of Acta Paediatrica, Professor Alex Levin, Director of the Pediatric Ophthalmology and Strabismus Service at Wills Eye Hospital, (PA, USA), expresses relevant concerns (1) about a report produced by the Swedish Agency for Technology Assessment of Health and Social Services (SBU) (2) and summarized in a paper by Lynøe et al (3). He also provides necessary input on the importance of the morphology and distribution of retinal hemorrhages in diagnosing different causes of retinal bleedings. SBU undertakes independent assessments of methods used in health, medical, dental and social services and services provided to persons with certain functional disabilities...
March 27, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28342881/pericardial-patch-graft-repair-of-severe-localized-scleral-thinning-encountered-during-strabismus-surgery
#5
Maan Alkharashi, Alexander F Dagi, Linda R Dagi
This article presents a surgical technique using a pericardial patch for the permanent repair of severe scleral thinning encountered during strabismus surgery. In the present case scleral thinning resulted from buckle removal. Familiarity with this technique may prove important for the strabismus surgeon treating patients with a history of surface ocular hardware or disease-induced scleral thinning.
March 22, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28341389/visual-outcomes-and-complications-of-cataract-surgery-with-primary-implantation-in-infants
#6
L Vera, N Lambert, J Sommet, R Boulkedid, C Alberti, E Bui Quoc
PURPOSE: To describe the visual results and postoperative complications of cataract surgery with primary intraocular lens (IOL) implantation performed in infants and to determine possible predictive factors related to poor visual outcome. METHODS: A retrospective consecutive case series of cataract surgeries with primary IOL implantation in infants was performed. Visual outcome and postoperative complications were recorded. A final visual acuity>0.5 logMAR was considered as a poor visual outcome...
March 21, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28338183/psychogenic-convergence-spasm-mimicking-ocular-myasthenia
#7
C Scoppetta, G Di Gennaro
A 14-year-old girl presented with a two-years history of fluctuating convergent strabismus, diplopia, and reading difficulty. She has been previously diagnosed by experienced neurologists as having ocular myasthenia and she had been treated for two years with anticholinesterase inhibitors and immunomodulatory drugs. After a thorough medical interview and neurological examination, a diagnosis of psychogenic convergence spasm was made. The patient was then reassured and the symptoms immediately disappeared. She also had psychotherapy and maintained a condition of sustained freedom from symptoms...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28336401/performance-of-the-spot-vision-screener-in-children-younger-than-three-years-of-age
#8
Blake D Forcina, M Millicent Peterseim, M Edward Wilson, Edward W Cheeseman, Samuel Feldman, Amanda L Marzolf, Bethany J Wolf, Rupal H Trivedi
PURPOSE: To evaluate the use of the Spot Vision Screener (Spot; Welch Allyn, Skaneateles Falls, NY) for detection of amblyopia risk factors in children aged 6 months to 3 years, as defined by the 2013 guidelines of the American Association for Pediatric Ophthalmology and Strabismus. DESIGN: Reliability analysis METHODS: In this study, children seen from 01 June 2012 to 30 April 2016 were tested with the Spot during a routine visit. Enrolled children underwent a comprehensive eye examination including cycloplegic refraction and sensorimotor testing within six months of the testing date by a pediatric ophthalmologist masked to the Spot results...
March 20, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28329891/treatment-of-extreme-strabismus-in-tao-thyroid-associated-orbitopathy-medial-rectus-and-inferior-rectus-tendon-elongation-as-an-alternative-to-conventional-strabismus-surgery-a-case-report
#9
M Wipf, A Palmowski-Wolfe
No abstract text is available yet for this article.
March 22, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28320694/rectus-muscle-excyclorotation-and-v-pattern-strabismus-a-quantitative-appraisal-of-clinical-relevance-in-syndromic-craniosynostosis
#10
Linda R Dagi, Sarah MacKinnon, David Zurakowski, Sanjay P Prabhu
PURPOSE: V-pattern strabismus observed with syndromic craniosynostosis has been attributed to disparate causes. We compared severity of V pattern with degree of excyclorotation of rectus muscles to appraise significance of this proposed aetiology. METHODS: 43 patients with Apert, Crouzon or Pfeiffer syndrome referred to Boston Children's Hospital Department of Ophthalmology were identified. 28 met inclusion criteria for retrospective cohort study, specifically: (1) sensorimotor measurements in minimum of seven cardinal gazes, (2) quantified fundus torsion and (3) orbital CT imaging sufficient to measure rectus muscle cyclorotation in coronal and quasicoronal planes, posteriorly (near orbital apex) and anteriorly (near pulleys)...
March 20, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28315737/botulinum-toxin-as-an-adjunct-to-monocular-recession-resect%C3%A4-on-surgery-for-large-angle-sensory-strabismus
#11
Betül Tuğcu, Eda Sönmezay, Fadime Nuhoğlu, Hakan Özdemir, Seyhan Bahar Özkan
PURPOSE: To evaluate the result of using intraoperative botulinum toxin A (BTA) as an adjunct to monocular recession-resection surgery in the management of large-angle sensory strabismus. METHODS: The medical records of patients diagnosed with sensory strabismus with constant large-angle strabismus were reviewed retrospectively to identify those who underwent monocular recession-resection surgery combined with 5 units of BTA injection into the recessed muscle of the nonfixating eye...
March 15, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28302533/strabismus-measurements-in-adults-before-and-after-pupil-dilation
#12
Sean S Rivera, Michael S Lee, Scott Lunos, Jill S Anderson, Erick D Bothun
PURPOSE: To determine the effect of dilating drops on strabismus measurements in adults. DESIGN: Prospective cohort study METHODS: Patients age 18 and older with strabismus underwent a standard evaluation of ocular motility, stereopsis, and ocular alignment with alternate prism cover test by a certified orthoptist. After pupil dilation with 2.5% phenylephrine and 1% tropicamide, ocular alignment was re-measured in primary gaze at 6 meters, at 1/3 meter and at 1/3 meter with a +3...
March 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28301497/long-term-outcomes-of-ciliary-sulcus-versus-capsular-bag-fixation-of-intraocular-lenses-in-children-an-ultrasound-biomicroscopy-study
#13
Yun-E Zhao, Xian-Hui Gong, Xue-Ning Zhu, He-Ming Li, Meng-Jun Tu, Terry G Coursey, Stephen C Pflugfelder, Feng Gu, Ding Chen
PURPOSE: To evaluate the long-term outcomes of ciliary sulcus versus capsular bag fixation of intraocular lenses (IOLs) in children after pediatric cataract surgery. METHODS: IOL was implanted in the ciliary sulcus in 21 eyes of 14 children, and in the capsular bag in 19 eyes of 12 children for the treatment of pediatric cataract in an institutional setting. Ultrasound biomicroscopy (UBM) was performed. Main outcome measures included IOL decentration, IOL tilt, anterior chamber depth (ACD), angle-opening distance at 500 μm (AOD500), trabecular-iris angle (TIA), best-corrected visual acuity (BCVA), intraocular pressure (IOP), and incidence of postoperative complications...
2017: PloS One
https://www.readbyqxmd.com/read/28292276/effect-of-modified-graded-recession-and-anteriorization-on-unilateral-superior-oblique-palsy-a-retrospective-study
#14
Dong Cheol Lee, Se Youp Lee
BACKGROUND: Several inferior oblique (IO) weakening methods exist for correction of superior oblique palsy (SOP). A previously reported method involved recession and anteriorization according to IO overaction (IOOA) grade, which might be subjective and cause upgaze limitation and opposite vertical strabismus. Therefore, this study attempted to examine the efficacy of modified graded recession and anteriorization of the IO muscle in correction of unilateral SOP without resulting in upgaze limitation or opposite vertical strabismus...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28291193/-surgical-rehabilitation-of-patients-with-thyroid-eye-disease-systematic-approach
#15
S E Avetisov, Ya O Grusha, D S Ismailova, P A Kochetkov, S S Danilov, N Yu Sviridenko
AIM: to analyze the results of surgical treatment of patients with thyroid eye disease (TED), including the type of surgery, indications, and outcomes. MATERIAL AND METHODS: Hundred thirty-nine patients with TED (112 females, 27 males) aged 45.8±13.6 years. RESULTS: Bony orbital decompression was performed in 91 patients (128 orbits). After the surgery, visual acuity increased from 0.84±0.47 up to 0.94±0.32 (р<0.05), exophthalmos got reduced by the average of 3...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28288914/a-double-masked-randomized-trial-of-postoperative-local-anesthetic-for-pain-control-in-pediatric-strabismus-surgery
#16
Laura B Enyedi, David K Wallace, Guy de L Dear
PURPOSE: To determine to what extent local anesthetic reduces postoperative pain after pediatric strabismus surgery. METHODS: In this double-masked, randomized clinical trial of 50 children 13-91 months of age undergoing strabismus surgery, subjects were randomly assigned to one of three treatments given at the conclusion of surgery: topical lidocaine gel and sub-Tenon's (balanced salt solution) placebo (n = 16), topical placebo (hypromellose) and sub-Tenon's bupivacaine 0...
March 10, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28286307/strabismus-surgery-outcomes-in-eyes-with-glaucoma-drainage-devices
#17
Carla J Osigian, Kara M Cavuoto, Julia D Rossetto, Mohamed Sayed, Sara Grace, Ta C Chang, Hilda Capo
PURPOSE: To report strabismus surgery outcomes in eyes with prior implantation of glaucoma drainage devices (GDD). METHODS: The medical records of patients who underwent strabismus surgery for ocular misalignment that developed after implantation of a GDD over a 13-year period at a single institution were examined retrospectively. Patient characteristics, deviation types, preoperative measurements, surgical procedures, and postoperative measurements were analyzed...
March 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28286306/a-controlled-study-of-the-role-of-cryopreserved-amniotic-membrane-transplant-during-strabismus-reoperations
#18
Rehab Rashad Kassem, Ahmed Mostafa Kamal, Randa Mohamed Abdel-Moneim El-Mofty, Hala Mostafa Elhilali
PURPOSE: To evaluate the effects of using cryopreserved human amniotic membrane (AM) transplant during strabismus reoperations. METHODS: A total of 30 patients with persistent strabismus were included in this controlled, prospective study. Patients were divided into two groups of 15 patients each. The AM group underwent strabismus reoperation with wrapping of the muscles with cryopreserved amniotic membrane. Controls underwent strabismus reoperation without an AM wrap...
March 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28278511/mechanism-of-microrna-146a-notch2-signaling-regulating-il-6-in-graves-ophthalmopathy
#19
Ning Wang, Feng-E Chen, Zi-Wen Long
BACKGROUND/AIMS: We intended to investigate the significance of microRNA-146a, Notch2 and IL-6 on Graves ophthalmopathy (GO) and the relationships among them. METHODS: About 27 GO patients were incorporated in this study, including 13 patients with inactive GO and14 patients with active GO. Another 15 patients who had previously received strabismus orthopedics or ophthalmectomy due to trauma were selected as the control population. QRT-PCR assay was used to detect microRNA-146a and Notch2 expression levels in plasma...
March 8, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28270191/isolation-and-molecular-characterisation-of-halicephalobus-gingivalis-in-the-brain-of-a-horse-in-piedmont-italy
#20
Maria Domenica Pintore, Francesco Cerutti, Antonio D'Angelo, Cristiano Corona, Paola Gazzuola, Loretta Masoero, Corrado Colombo, Roberto Bona, Carlo Cantile, Simone Peletto, Cristina Casalone, Barbara Iulini
BACKGROUND: A fatal case of meningoencephalitis was reported in a 13-year-old Koninklijk Warmbloed Paard Nederland stallion, suspected of West Nile virus (WNV) infection, in the Piedmont region of Italy. Clinical signs included right head tilt and circling, depression alternated with excitability, fever and lateral strabismus. Combined treatment consisting of dimethylsulfoxide, dexamethasone, sulphonamides and sedative was administered, but because of the poor conditions the horse was euthanatized and submitted for necropsy...
March 7, 2017: Parasites & Vectors
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