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https://www.readbyqxmd.com/read/29771752/radiotherapy-for-active-thyroid-eye-disease
#1
Kyle J Godfrey, Michael Kazim
PURPOSE: To critically review the published literature on orbital radiotherapy as a treatment modality for thyroid eye disease (TED). METHODS: A systematic review and analysis of the relevant published literature was performed. RESULTS: Thyroid eye disease is an autoimmune condition that is amenable to treatments that modulate the immune response, including orbital radiotherapy (ORT). Ideal candidates for ORT are patients in the early, active phase of TED with moderate to severe, or rapidly progressive, disease, including patients with significant motility deficits and compressive optic neuropathy...
May 2, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29770635/clinical-course-and-prognostic-factors-of-acquired-third-fourth-and-sixth-cranial-nerve-palsy-in-korean-patients
#2
Kiyoung Kim, Sung Rae Noh, Min Seok Kang, Kyung Hyun Jin
PURPOSE: This study aimed to evaluate the clinical course and prognostic factors of acquired third, fourth, and sixth cranial nerve (CN) palsy grouped according to etiology. METHODS: This study involved a retrospective review of the medical records of 153 patients who were diagnosed with acquired paralytic strabismus from January 2004 to July 2015. Outcomes, recovery rates, and time to recovery were investigated according to the affected CN: CN3, CN4, and CN6 palsies...
March 20, 2018: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29766557/risk-factors-for-ocular-complications-in-periocular-infantile-hemangiomas
#3
Liat Samuelov, Michael Kinori, Karen Rychlik, Meghana Konanur, Sarah L Chamlin, Bahram Rahmani, Anthony J Mancini
BACKGROUND/OBJECTIVES: Infantile hemangiomas are the most common benign tumors of childhood. Although some children with periocular infantile hemangiomas do not require treatment, these lesions may result in amblyopia and visual impairment if not properly treated. We have attempted to characterize clinical features of periocular infantile hemangiomas that predict negative ocular outcomes and thus require prompt referral to an ophthalmologist and initiation of therapy. METHODS: This study included children with periocular infantile hemangiomas consecutively seen at Ann & Robert H...
May 15, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29756712/traumatic-cataract-surgery-in-pediatric-patients-experience-in-a-site
#4
Verónica Y Burgos-Elías, Ma José Marroquín-Sarti, Martin A Zimmermann-Paiz, Ana Marissa Ordoñez Rivas, Nancy C Quezada-Del Cid
of this study was to determine the characteristics of patients younger than 14 years who underwent traumatic cataract surgery at the Unit of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology "Dra. Ana María Illescas Putzeys" of Hospital de Ojos y Oídos "Dr. Rodolfo Robles V." A retrospective, descriptive, and observational study was carried out to review the medical records of patients who underwent cataract surgery between 2010 and 2015. A total of 54 children underwent traumatic cataract surgery; 75% were boys; 68% were in the 6-11-year-old age range...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29752995/a-novel-surgical-technique-employing-donor-sclera-in-strabismus-surgery
#5
Rannveig Linda Thorisdottir, Rafi Sheikh, Jonas Blohmé, Göran Stigmar, Malin Malmsjö
No abstract text is available yet for this article.
May 9, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29747370/-the-influence-of-igf-%C3%A2-on-the-expression-of-myf5-and-tgf-%C3%AE-1-in-medial-rectus-muscle-of-cat-model-with-strabismus
#6
G W Li, G X Liu, Y N Yin, T Liu
Objective: To observe the influence of exogenous insulin-like growth factor-Ⅰ(IGF-Ⅰ) on the expression of myocyte differentiation factor 5 (Myf5) and transforming growth factor β1(TGF-β1) in medial rectus muscle of cat model with strabismus. Methods: Experiment research. Twenty-seven kittens which were in sensitive period of visual development (4-6 weeks old), were randomly divided into experimental, control and blank control groups by random numbers table method. Each experimental group was further divided into 3 sub-groups (4 weeks, 8 weeks and 12 weeks) based on drug intervention time, hence 3 kittens in each sub-group...
May 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29747358/-the-causative-diseases-common-comorbidities-and-surgical-procedures-of-948-cases-of-horizontal-sensory-strabismus
#7
L Yin, X Chen
Objective: To investigate the common causes, onset age of vision impairment and complications of sensory strabismus, and to explore the effective surgical methods for sensory strabismus and associated complications. Methods: In this retrospective study, there were 948 cases of surgical treatment for sensory strabismus from 2005 to 2015 in Tianjin Eye Hospital, including 822 cases of sensory exotropia and 126 cases of sensory esotropia. Causative disease, onset age of vision impairment, eye movement, horizontal and vertical deviation and surgical methods were evaluated...
April 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29737052/retinoblastoma-for-pediatric-ophthalmologists
#8
Alaa AlAli, Stephanie Kletke, Brenda Gallie, Wai-Ching Lam
Retinoblastoma can present in 1 or both eyes and is the most common intraocular malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor suppressor gene, leading to malignant transformation of primitive retinal cells. The most common presentation is leukocoria, followed by strabismus. Heritable retinoblastoma accounts for 45% of all cases, with 80% being bilateral. Treatment and prognosis of retinoblastoma is dictated by the disease stage at initial presentation. The 8th Edition American Joint Committee on Cancer (AJCC) TNMH (tumor, node, metastasis, heritable trait) staging system defines evidence-based clinical and pathological staging for overall prognosis for eye(s) and child...
May 8, 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29733898/intravenous-dexmedetomidine-augments-the-oculocardiac-reflex
#9
Robert W Arnold, Russell Biggs, Brion Beerle
BACKGROUND: We reported that premedication with nasal dexmedetomidine was associated with a more intense oculocardiac reflex (OCR). In this study we performed an intrasubject, intravenous comparison to test our hypothesis that this alpha-adrenergic agonist potentiates the trigemino-vagal reflex. METHODS: OCR (greatest change heart rate/baseline heart rate) was prospectively monitored with 10-second, square-wave 200 g tension on the inferior rectus or other muscles during strabismus surgery...
May 4, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29730798/effects-of-an-infratrochlear-nerve-block-on-reducing-the-oculocardiac-reflex-during-strabismus-surgery-a-randomized-controlled-trial
#10
Seung-Hyun Kim, Hyun Jin Shin
PURPOSE: To determine whether an infratrochlear nerve block (ITB) can reduce the oculocardiac reflex (OCR) during strabismus surgery on the medial rectus muscle (MR). METHODS: This prospective, randomized single-masked study included 60 patients with intermittent exotropia scheduled for unilateral MR resection/lateral rectus recession under general anesthesia. Patients were randomly allocated to receive a regional nerve block of the infratrochlear nerve (ITB group) prior to surgery or standard treatment without a nerve block (control group)...
May 5, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29729448/quality-of-life-and-neuropsychiatric-disorders-in-patients-with-graves-orbitopathy-current-concepts
#11
REVIEW
Alice Bruscolini, Marta Sacchetti, Maurizio La Cava, Marcella Nebbioso, Angela Iannitelli, Adele Quartini, Alessandro Lambiase, Massimo Ralli, Armando de Virgilio, Antonio Greco
Graves' disease (GD) is an autoimmune chronic thyroiditis frequently associated with development of Graves' orbitopathy (GO) characterized by proptosis, strabismus, impairment of visual function, ocular surface inflammation and dry eye. As consequence, patients with GO experience impairment of quality of life and social function and could develop a neurobehavioral syndrome, ranging from anxious to depressive or psychotic disorders. To date, the pathogenic mechanism underlying neuropsychiatric disorders in patients with GD has not been clearly understood...
May 2, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29714107/intermittent-esotropia-in-4-patients-with-allan-herndon-dudley-syndrome
#12
Cole J Swiston, David L Nash
Allan-Herndon-Dudley syndrome is a rare X-linked neurologic condition caused by mutations in monocarboxylate transporter 8 ( MCT8), which leads to deficient thyroid hormone transport. Typical features include severe cognitive impairment, truncal hypotonia, spastic paraplegia, weakness, and speech difficulties. Minimal literature exists describing the ocular findings in patients with Allan-Herndon-Dudley syndrome. We describe 4 male siblings affected with Allan-Herndon-Dudley syndrome with a novel nonsense mutation (Q90X) in the MCT8 protein...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29709045/clinical-research-on-the-efficacy-of-modified-surgery-for-esotropia-fixus-with-high-myopia
#13
Dongmei Qi, Lixia Gao, Jing Xie, Tao Yu
PURPOSE: To investigate the efficacy of a modified surgical procedure for esotropia fixus with high myopia. METHODS: Thirteen patients (15 eyes) with esotropia fixus and high myopia who underwent the Jensen procedure for superior and lateral rectus muscles at Southwest Hospital between February 2014 and December 2015 were retrospectively analyzed. Intraoperatively, the superior rectus and lateral rectus muscles were separated up to 12 to 14 mm posterior to their respective insertion...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29709044/congenital-nasolacrimal-duct-obstruction-and-its-association-with-the-mode-of-birth
#14
Mansha Palo, Shweta Gupta, Milind N Naik, Mohammad Javed Ali
PURPOSE: To assess the association of congenital nasolacrimal duct obstruction (CNLDO) with mode of birth (vaginal or cesarean). METHODS: This study was a prospective interventional case series of 200 consecutive cases of CNLDO presenting at a tertiary care center. Data collected include demographics, mode of delivery, elective or emergency cesarean section, primary or secondary cesarean sections, type of CNLDO (simple or complex), management, and outcomes. Statistical significance was set at a P value of less than ...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29709043/pediatric-eales-disease-an-indian-tertiary-eye-center-experience
#15
Parthopratim Dutta Majumder, Ranju Kharel Sitaula, Jyotirmay Biswas
PURPOSE: To report the clinical profiles, etiologies, treatment modalities, and outcomes for Eales disease in patients younger than age 16 years in India. METHODS: Retrospective review of medical records of patients with Eales disease who had a minimum 5-year follow-up period. RESULT: A total of 25 eyes of 13 patients were included. Of these 13 patients, 12 (94%) had bilateral Eales disease and 11 (84.6%) were men. Mean patient age was 14...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29709042/immediate-postoperative-alignment-measurements-as-a-predictor-of-alignment-stability-in-fixed-suture-strabismus-surgery
#16
Charline S Boente, Griffin J Jardine, Tina G Damarjian, Derek T Sprunger, Gavin J Roberts, Daniel E Neely, Kathryn M Haider, David A Plager
PURPOSE: To evaluate the use of immediate postoperative alignment measurements as a predictor of future alignment stability in fixed suture strabismus surgery. METHODS: Forty-seven patients were prospectively evaluated after undergoing horizontal or vertical rectus muscle surgery using a fixed suture technique. Alignment measurements were taken approximately 1 hour, 1 to 3 weeks, and 2 to 3 months postoperatively. A Spearman correlation coefficient was used to compare measurements from the immediate postoperative period to the 2- to 3-month postoperative period...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29709041/infantile-exotropia-and-developmental-delay
#17
Gregg T Lueder, Marlo Galli
PURPOSE: To evaluate a group of infants with this disorder to determine the long-term outcome of surgery and to assess the need for neurologic evaluations. METHODS: This interventional case series reviewed the records of infants who underwent surgery for the treatment of exotropia with onset during the first year of life. The preoperative ophthalmic and systemic findings, treatment, and developmental and ophthalmic outcomes were reviewed. Surgery was considered successful if the horizontal deviation was less than 10 prism diopters (PD)...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29709040/pediatric-frontalis-suspension-with-braided-polyester-a-comparison-of-two-techniques
#18
Andrea Molinari, Daniel T Weaver, Todd A Goldblum, David Silbert, Sebastian P Lopez, Noelle Matta
PURPOSE: To demonstrate the benefits of using braided polyester in the management of severe or recurrent ptosis in children and young adults and to compare the efficacy of two surgical techniques. METHODS: Retrospective, non-randomized record review of 30 patients (43 eyelid procedures) affected by congenital or acquired severe ptosis who underwent frontalis suspension with braided polyester from 2008 to 2016. Two surgical techniques were compared: the base-down triangle and the Fox pentagon, both of which were performed using a closed technique...
April 27, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29704131/factors-influencing-stereopsis-in-patients-with-both-refractive-accommodative-esotropia-and-amblyopia
#19
Burçin Çakır, Özlem Bursalı, Sedat Özmen, Nilgün Özkan Aksoy, Tural Babashli, Gursoy Alagöz
PURPOSE: Potential factors influencing stereopsis were investigated in patients with both refractive accommodative esotropia (RAE) and amblyopia. MATERIALS AND METHODS: A retrospective chart review was performed to find out all patients with the diagnosis of both RAE and amblyopia. Patients are classified into two groups: group 1 (with stereopsis) and group 2 (without stereopsis). Onset age of RAE, history of strabismus in family members, time of amblyopia treatment, mean spherical equivalent, anisometropia, ocular movement disorders, especially, overaction of inferior oblique (IO) muscle, visual acuity difference (VAD) between eyes, best-corrected visual acuity (BCVA) levels of amblyopic and normal eyes and the presence of alternation of fixation (AOF) were investigated as possible factors...
April 27, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29703020/flumazenil-reduces-respiratory-complications-during-anesthesia-emergence-in-children-with-preoperative-upper-respiratory-tract-infections
#20
Ruiqiang Sun, Guolin Wang, Xuesong Gao, Shuzhen Wang
Despite its benignity, upper respiratory infections (URIs) 1 increase the risk of postoperative respiratory complications during the perioperative and postoperative periods. Flumazenil could improve the symptoms of respiratory obstruction.To evaluate the effect of flumazenil on the occurrence of respiratory complications during anesthesia emergence of children with preoperative URI.This was a prospective study of 164 consecutive pediatric patients who underwent strabismus surgery under general anesthesia at the Tianjin Eye Hospital between August 2016 and April 2017...
April 2018: Medicine (Baltimore)
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