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https://www.readbyqxmd.com/read/28060245/the-hook-and-release-technique-during-enucleation-surgery
#1
David R Jordan, Bazil Stoica, Jonathan J Dutton
PURPOSE: To describe the results and potential benefit of direct muscle release from the globe during enucleation surgery without identifying sutures in the rectus muscle insertion sites, a technique referred to as the hook and release technique. METHODS: Single center, retrospective chart review of patients who underwent enucleation with direct removal of the rectus muscles without identifying sutures in their insertion sites between January 2011 and September 2015 was carried out...
January 5, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28057455/comparison-of-botulinum-toxin-with-surgery-for-the-treatment-of-acute-onset-comitant-esotropia-in-children
#2
Michael J Wan, Iason S Mantagos, Ankoor S Shah, Melanie Kazlas, David G Hunter
PURPOSE: To determine whether botulinum toxin is as effective as strabismus surgery in the treatment of acute-onset, comitant esotropia in children. DESIGN: Retrospective, non-randomized, comparative clinical study. METHODS: Setting: Tertiary care pediatric hospital. STUDY POPULATION: 49 children with acute-onset, comitant esotropia. INTERVENTION: Treatment with either botulinum toxin ("chemodenervation group") or standard incisional strabismus surgery ("surgery group")...
January 2, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28050460/profile-of-amblyopia-in-school-going-5-15-years-children-at-state-level-referral-hospital-in-uttarakhand
#3
Manisha Gupta, Sudhir Kumar Rana, Sanjiv Kumar Mittal, R N P Sinha
INTRODUCTION: Amblyopia is one of the common causes of childhood visual impairment. The prevalence of amblyopia usually varies according to the age group of the studied population and the factors prevailing in that region. The upper limit of the critical time when amblyopia can develop is around eight years of age and it can be permanent if corrective measures are not taken in time. AIM: The purpose of study was to know the profile and pattern of amblyopia in children aged 5-15 years with refractive error in Uttarakhand and to compare it with national and regional (South Asian) studies...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050326/use-of-botulinum-neurotoxin-in-ophthalmology
#4
REVIEW
Emel Başar, Ceyhun Arıcı
Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines, or crow's feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28045721/case-report-red-urine-after-day-care-strabismus-surgery
#5
Pregardien Caroline, Nassogne Marie-Cécile, Yuksel Demet, Veyckemans Francis
In the absence of surgery on the urinary tract, the emission of red urine after anesthesia should be considered as a diagnostic emergency because it can be a sign of hematuria, hemoglobinuria, blood transfusion reaction, significant myoglobinuria, or porphyria.This case describes the management of a 12-year-old boy who presented red urine at the day care unit after strabismus surgery.
December 30, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/28040132/molecular-cytogenetic-characterization-of-mosaicism-for-a-small-supernumerary-marker-chromosome-derived-from-chromosome-8-or-r-8-p12%C3%A2-q13-1-associated-with-phenotypic-abnormalities
#6
Chih-Ping Chen, Shuan-Pei Lin, Yi-Hui Lin, Schu-Rern Chern, Peih-Shan Wu, Yen-Ni Chen, Shin-Wen Chen, Chien-Wen Yang, Wen-Lin Chen, Wayseen Wang
OBJECTIVE: We present molecular cytogenetic characterization of mosaicism for a small supernumerary marker chromosome (sSMC) derived from chromosome 8. MATERIALS AND METHODS: A 35-year-old woman underwent amniocentesis at 16 weeks of gestation because of advanced maternal age. Amniocentesis revealed a karyotype of 47,XY,+mar[20]/46,XY[39]. However, array comparative genomic hybridization analysis on the subcultured amniocytes revealed no genomic imbalance. Prenatal ultrasound showed bilateral ventriculomegaly, intrauterine growth restriction, and an enlarged right atrium...
December 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28033651/axons-get-ahead-insights-into-axon-guidance-and-congenital-cranial-dysinnervation-disorders
#7
REVIEW
John K Chilton, Sarah Guthrie
Cranial nerves innervate head muscles in a well-characterised and highly conserved pattern. Identification of genes responsible for human congenital disorders of these nerves, combined with the analysis of their role in axonal development in animal models has advanced understanding of how neuromuscular connectivity is established. Here we focus on the ocular motor system, as an instructive example of the success of this approach in unravelling the aetiology of human strabismus. The discovery that ocular motility disorders can arise from mutations in transcription factors, including HoxA1, HoxB1, MafB, Phox2A and Sall4, has revealed gene regulatory networks that pattern the brainstem and/or govern the differentiation of cranial motor neurons...
December 29, 2016: Developmental Neurobiology
https://www.readbyqxmd.com/read/28031397/electrical-stimulation-of-superior-colliculus-affects-strabismus-angle-in-monkey-models-for-strabismus
#8
Suraj Upadhyaya, Hui Meng, Vallabh E Das
Disruption of binocular vision during the critical period for development leads to eye misalignment in humans and in monkey models. We have previously suggested that disruption within a vergence circuit could be the neural basis for strabismus. Electrical stimulation in the rostral superior colliculus (rSC) leads to vergence eye movements in normal monkeys. Therefore the purpose of this study was to investigate the effect of SC stimulation on eye misalignment in strabismic monkeys. Electrical stimulation was delivered to 51 sites in the intermediate and deep layers of the SC (400Hz, 0...
December 28, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28027694/awareness-and-perception-of-strabismus-among-the-youths-and-women-of-child-bearing-age-in-a-local-government-in-south-western-nigeria
#9
Olubunmi Bodunde, Tamramat Runsewe-Abiodun, Adekunle Alabi, Janet Adetunji, Michael Olowonyo, Bolanle Adefuye
Purpose To determine the awareness and perception of strabismus among the youths and women of child-bearing age in Ikenne Local Government Area (LGA) of Ogun State, South Western Nigeria. Methodology Fifteen focus group discussions (FGDs) were carried out in the LGA on the perceptions and attitudes of people to strabismus. Their responses were tape-recorded and later transcribed. A thematic phenomenological approach was used for the analysis. Result A total of 139 people participated in the FGDs, with a male:female ratio of 1:∼4...
January 1, 2016: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/28018672/acute-acquired-comitant-esotropia-in-adults-is-it-neurologic-or-not
#10
Kadriye Erkan Turan, Tulay Kansu
Objectives. Acute acquired comitant esotropia (AACE) can be a diagnostic challenge for ophthalmologists and neurologists because of its association with neurological pathologies. Our study describes a series of adult patients with AACE of undetermined etiology. Methods. Data on the clinical findings of patients presented with AACE of undetermined etiology with a minimum follow-up of 1 year were retrieved from the medical records and the results analyzed. Results. A series of 9 esotropia cases (age range: 20-43 years) was reviewed...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28017370/de-novo-mutations-in-ebf3-cause-a-neurodevelopmental-syndrome
#11
Hannah Sleven, Seth J Welsh, Jing Yu, Mair E A Churchill, Caroline F Wright, Alex Henderson, Rita Horvath, Julia Rankin, Julie Vogt, Alex Magee, Vivienne McConnell, Andrew Green, Mary D King, Helen Cox, Linlea Armstrong, Anna Lehman, Tanya N Nelson, Jonathan Williams, Penny Clouston, James Hagman, Andrea H Németh
Early B cell factor 3 (EBF3) is an atypical transcription factor that is thought to influence the laminar formation of the cerebral cortex. Here, we report that de novo mutations in EBF3 cause a complex neurodevelopmental syndrome. The mutations were identified in two large-scale sequencing projects: the UK Deciphering Developmental Disorders (DDD) study and the Canadian Clinical Assessment of the Utility of Sequencing and Evaluation as a Service (CAUSES) study. The core phenotype includes moderate to severe intellectual disability, and many individuals exhibit cerebellar ataxia, subtle facial dysmorphism, strabismus, and vesicoureteric reflux, suggesting that EBF3 has a widespread developmental role...
January 5, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28009406/the-frequency-and-causes-of-abnormal-head-position-based-on-an-ophthalmology-clinic-s-findings-is-it-overlooked
#12
Kadriye Erkan Turan, Hande Taylan Sekeroglu, Irem Koc, Meltem Kilic, Ali S Sanac
PURPOSE: To determine the frequency of abnormal head position (AHP) and identify the underlying causes in patients who presented to an ophthalmology clinic due to any ophthalmologic complaint. METHODS: The medical records of patients who presented with any ophthalmologic symptoms during a 6-month period were prospectively evaluated. In all, 2,710 patients (1,492 female and 1,218 male) aged 6 months-91 years were included in the study. Each patient underwent complete ophthalmologic evaluation...
December 2, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28006074/openeyesim-a-biomechanical-model-for-simulation-of-closed-loop-visual-perception
#13
Alexander Priamikov, Maria Fronius, Bertram Shi, Jochen Triesch
We introduce OpenEyeSim, a detailed three-dimensional biomechanical model of the human extraocular eye muscles including a visualization of a virtual environment. The main purpose of OpenEyeSim is to serve as a platform for developing models of the joint learning of visual representations and eye-movement control in the perception-action cycle. The architecture and dynamic muscle properties are based on measurements of the human oculomotor system. We show that our model can reproduce different types of eye movements...
December 1, 2016: Journal of Vision
https://www.readbyqxmd.com/read/27987368/postnatal-systemic-inflammation-and-neuro-ophthalmologic-dysfunctions-in-extremely-low-gestational-age-children
#14
Mari Holm, Dordi Austeng, Raina N Fichorova, Elizabeth N Allred, Karl C K Kuban, T Michael O'Shea, Olaf Dammann, Alan Leviton
AIM: Compared to infants born at term, children born very preterm are at increased risk of visual dysfunctions, and neonatal systemic inflammation. Here we explore if these two propensities are related. METHODS: As part of the ELGAN study, the concentrations of 16 mediators of inflammation were measured in blood obtained on postnatal days 1, 7, 14, 21 and 28 from 1062 children born before the 28(th) week of gestation. Presence of visual field deficit, strabismus, and/or impaired visual fixation was recorded at age two...
December 17, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27981923/tumor-regression-patterns-in-retinoblastoma
#15
Saemah Nuzhat Zafar, Sorath Noorani Siddiqui, Naima Zaheer
OBJECTIVE: To observe the types of tumor regression after treatment, and identify the common pattern of regression in our patients. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Department of Pediatric Ophthalmology and Strabismus, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from October 2011 to October 2014. METHODOLOGY: Children with unilateral and bilateral retinoblastoma were included in the study...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27980359/difference-of-self-identity-levels-between-strabismus-patients-and-normal-controls
#16
Youngjun Kim, Cheron Kim, Seongjae Kim, Yongseop Han, Inyoung Chung, Seongwook Seo, Jongmoon Park, Jimyong Yoo
PURPOSE: To evaluate differences in self-identity in patients diagnosed with strabismus, patients who underwent strabismus surgery, and healthy control individuals. METHODS: Self-identity testing was done during a military service physical examination. There were three subject groups: subjects with strabismus (group 1), subjects who had undergone corrective strabismus surgery (group 2), and subjects free of strabismus (group 3). The self-identity test was comprised of six sub-sections (subjectivity, self-acceptance, future confidence, goal orientation, initiative, and familiarity)...
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27977038/clinical-presentation-and-outcomes-of-stage-iii-or-stage-iv-retinoblastoma-in-80-asian-indian-patients
#17
Swathi Kaliki, Anamika Patel, Sadiya Iram, Vijay Anand Reddy Palkonda
PURPOSE: To describe the clinical features and outcomes of patients with stage III or IV retinoblastoma. METHODS: This was a retrospective study of 80 patients. RESULTS: Based on the International Retinoblastoma Staging System (IRSS), the tumors (n = 81) belonged to stage IIIa (n = 38, 47%), IIIb (n = 1, 1%), IVa2 (n = 10, 12%), IVb1 (n = 14, 17%), and IVb3 (n = 18, 22%). Of 80 patients, 42 (53%) were compliant to treatment and 38 (47%) were non-compliant...
December 8, 2016: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27977037/a-high-prevalence-of-exotropia-in-patients-with-duane-retraction-syndrome-in-a-tertiary-eye-care-center-in-south-india
#18
Manjushree Bhate, Virender Sachdeva, Ramesh Kekunnaya
PURPOSE: To determine the prevalence and clinical characteristics of patients with Duane retraction syndrome presenting with exotropia in a tertiary eye care center. METHODS: Medical records of 140 patients with Duane retraction syndrome and exotropia (of the total 441 patients with Duane retraction syndrome) seen from 2000 to 2009 were reviewed. Characteristics studied included age at presentation, gender, laterality, manifest primary position, abnormal head posture, ocular motility, and overshoots...
December 8, 2016: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27977036/changing-strabismus-surgery-distribution-at-shanxi-province-eye-hospital-in-central-china
#19
Jun Hong Li, Wen Fang Xie, Jiao Ni Tian, Li Jun Zhang, Miao Miao Cao, Li Wang
PURPOSE: To investigate whether there has been a changing trend of strabismus surgery in a provincial eye hospital in the central part of China over the past decade. METHODS: This was a retrospective analysis of data on all strabismus surgery performed in Shanxi Province Eye Hospital in China during the past 10 years. Recorded characteristics included patient demographics, type of strabismus, age, and gender. RESULTS: A total of 12,327 patients received strabismus surgery in the eye hospital from 2005 to 2014...
December 8, 2016: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27977035/detecting-high-hyperopia-the-plus-lens-test-and-the-spot-vision-screener
#20
Samuel Feldman, Mae Millicent W Peterseim, Rupal H Trivedi, M Edward Wilson, Edward W Cheeseman, Carrie E Papa
PURPOSE: To evaluate the usefulness of the Plus Lens (Goodlite Company, Elgin, IL) test and the Spot Vision Screener (Welch Allyn, Skaneateles Falls, NY) in detecting high hyperopia in a pediatric population. METHODS: Between June and August 2015, patients were screened with the Spot Vision Screener and the Plus Lens test prior to a scheduled pediatric ophthalmology visit. The following data were analyzed: demographic data, Plus Lens result, Spot Vision Screener result, cycloplegic refraction, and examination findings...
December 8, 2016: Journal of Pediatric Ophthalmology and Strabismus
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