keyword
MENU ▼
Read by QxMD icon Read
search

Adventitious

keyword
https://www.readbyqxmd.com/read/28439279/metabolic-investigation-of-phelipanche-aegyptiaca-reveals-significant-changes-during-developmental-stages-and-in-its-different-organs
#1
Noam Nativ, Yael Hacham, Joseph Hershenhorn, Evgenia Dor, Rachel Amir
Phelipanche aegyptiaca Pers. is a root holoparasitic plant considered to be among the most destructive agricultural weeds worldwide. In order to gain more knowledge about the metabolic profile of the parasite during its developmental stages, we carried out primary metabolic and lipid profiling using GC-MS analysis. In addition, the levels of amino acids that incorporate into proteins, total protein in the albumin fraction, nitrogen, reduced sugars, and phenols were determined. For the assays, the whole plants from the four developmental stages-tubercle, pre-emergent shoot, post-emergent shoot, and mature flowering plants-were taken...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28436527/electrowetting-on-conductors-anatomy-of-the-phenomenon
#2
Kontad Ounnunkad, Hollie V Patten, Matěj Velický, Anna K Farquhar, Paula A Brooksby, Alison J Downard, Robert A W Dryfe
We have recently reported that reversible electrowetting can be observed on the basal plane of graphite, without the presence of a dielectric layer, in both liquid/air and liquid/liquid configurations. The influence of carbon structure on the wetting phenomenon is investigated in more detail here. Specifically, it is shown that the adsorption of adventitious impurities on the graphite surface markedly suppresses the electrowetting response. Similarly, the use of pyrolysed carbon films, although exhibiting a roughness below the threshold previously identified as the barrier to wetting on basal plane graphite, does not give a noticeable electrowetting response, which leads us to conclude that specific interactions at the water-graphite interface as well as graphite crystallinity are responsible for the reversible response seen in the latter case...
April 24, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28434701/upregulated-interleukins-il-6-il-10-and-il-13-in-immunoglobulin-g4-related-aortic-aneurysm-patients
#3
Satomi Kasashima, Atsuhiro Kawashima, Yoh Zen, Satoru Ozaki, Fuminori Kasashima, Masamitsu Endo, Yasushi Matsumoto, Kengo Kawakami
OBJECTIVE: Immunoglobulin (Ig) G4-related aortic aneurysms (IgG4-AAs) are a special aortic aneurysm among IgG4-related diseases (IgG4-RDs), which are inflammatory and fibrous conditions characterized by tumorous swelling of affected organs and high serum IgG4 concentrations. Recently, IgG4-RD pathogenesis was shown to be associated with T-helper-2 (Th2) and regulatory T (Treg) dominant cytokine production, such as interleukin (IL)-4, IL-10, and IL-13. IL-6 is a key proinflammatory cytokine contributing to lymphocyte and plasmacyte maturation and to atherosclerosis and aneurysm development...
April 20, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28432057/imaging-and-modeling-of-acute-pressure-induced-changes-of-collagen-and-elastin-microarchitectures-in-pig-and-human-resistance-arteries
#4
Maria Bloksgaard, Thomas M Leurgans, Bart Spronck, Maarten Hg Heusinkveld, Bjarne Thorsted, Kristoffer Rosenstand, Inger Nissen, Ulla Melchior Hansen, Jonathan R Brewer, Luis A Bagatolli, Lars M Rasmussen, Akhmadjon Irmukhamedov, Koen D Reesink, Jo G R De Mey
The impact of disease related changes in the extracellular matrix (ECM) on the mechanical properties of human resistance arteries largely remains to be established. Resistance arteries from both pig and human parietal pericardium (PRA) display a different ECM microarchitecture compared to frequently used rodent mesenteric arteries. We hypothesized that the biaxial mechanics of PRA mirror pressure induced changes in the ECM microarchitecture. This was tested using isolated pig PRA as model system, integrating vital imaging, pressure myography and mathematical modeling...
April 21, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28420427/isolation-and-characterization-of-equine-native-msc-populations
#5
Cristina L Esteves, Tara A Sheldrake, Simone P Mesquita, Juan J Pesántez, Timothy Menghini, Lucy Dawson, Bruno Péault, F Xavier Donadeu
BACKGROUND: In contrast to humans in which mesenchymal stem/stromal cell (MSC) therapies are still largely in the clinical trial phase, MSCs have been used therapeutically in horses for over 15 years, thus constituting a valuable preclinical model for humans. In human tissues, MSCs have been shown to originate from perivascular cells, namely pericytes and adventitial cells, which are identified by the presence of the cell surface markers CD146 and CD34, respectively. In contrast, the origin of MSCs in equine tissues has not been established, preventing the isolation and culture of defined cell populations in that species...
April 18, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28415796/macrophage-stimulated-microrna-expression-in-mural-cells-promotes-transplantation-induced-neointima-formation
#6
Xiaotong Guo, Mengyao Sun, Chaochao Dai, Xun Zhang, Qihui Yin, Jiaqi Ling, Xinyue Li, Xiao Wu, Fan Jiang, Jianli Wang
In this study, we tested the possibility that macrophages might contribute to neointima formation by stimulating microRNA expressions in mural cells. Thoracic aortas from F344 rats were transplanted into recipient Lewis rats. Clodronate liposome was used for in vivo macrophage depletion. Using miR-21 as a prototypic example of vascular enriched microRNA, we showed that macrophage depletion reduced the expression level of miR-21, which was upregulated in the allograft. This effect of macrophage depletion was accompanied by attenuations in neointimal hyperplasia and transplantation-induced vascular inflammation...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28412645/a-hidden-structural-vulnerability-in-the-thrombospondin-2-deficient-aorta-increases-the-propensity-to-intramural-delamination
#7
C Bellini, N J Kristofik, M R Bersi, T R Kyriakides, J D Humphrey
Mice lacking thrombospondin-2 (TSP2) represent an animal model of impaired collagen fibrillogenesis. Collagen constitutes ~1/3 of the wall of the normal murine descending thoracic aorta (DTA) and is thought to confer mechanical strength at high pressures. Microstructural analysis of the DTA from TSP2-null mice revealed irregular and disorganized collagen fibrils in the adventitia and at the interface between the media and adventitia. Yet, biaxial mechanical tests performed under physiologic loading conditions showed that most mechanical metrics, including stress and stiffness, were not different between mutant and control DTAs at 20- and 40-weeks of age, thus suggesting that the absence of TSP2 is well compensated under normal conditions...
March 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28411234/phenotype-of-gaba-transaminase-deficiency
#8
Mary Kay Koenig, Ryan Hodgeman, James J Riviello, Wendy Chung, Jennifer Bain, Claudia A Chiriboga, Kazushi Ichikawa, Hitoshi Osaka, Megumi Tsuji, K Michael Gibson, Penelope E Bonnen, Phillip L Pearl
OBJECTIVE: We report a case series of 10 patients with γ-aminobutyric acid (GABA)-transaminase deficiency including a novel therapeutic trial and an expanded phenotype. METHODS: Case ascertainment, literature review, comprehensive evaluations, and long-term treatment with flumazenil. RESULTS: All patients presented with neonatal or early infantile-onset encephalopathy; other features were hypotonia, hypersomnolence, epilepsy, choreoathetosis, and accelerated linear growth...
April 14, 2017: Neurology
https://www.readbyqxmd.com/read/28409324/generation-and-characterization-of-polyclonal-and-monoclonal-antibodies-to-human-ntpdase2-including-a-blocking-antibody
#9
Julie Pelletier, Hervé Agonsanou, Ninotchska Delvalle, Michel Fausther, Mabrouka Salem, Brian Gulbransen, Jean Sévigny
Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) is an ectonucleotidase that modulates P2 receptor activation by hydrolyzing ATP to ADP. In rodents, NTPDase2 is expressed by several specialized cell types such as vascular adventitial cells, neuroglial cells, hepatic portal fibroblasts, gustatory type I cells, and cells within the connective tissues of reproductive and gastrointestinal organs. Much less is known regarding the expression and function of NTPDase2 in humans. Here, we developed specific research tools to study human NTPDase2...
April 13, 2017: Purinergic Signalling
https://www.readbyqxmd.com/read/28402942/mesenchymal-stem-cells-and-their-therapeutic-applications-in-inflammatory-bowel-disease
#10
REVIEW
Fei Mao, Qiang Tu, Li Wang, Fuliang Chu, Xia Li, Haiyan S Li, Wenrong Xu
Mesenchymal stem or stromal cells (MSCs) are non-hematopoietic stem cells that facilitate tissue regeneration through mechanisms involving self-renewal and differentiation, supporting angiogenesis and tissue cell survival, and limiting inflammation. MSCs were originally identified and expanded in long-term cultures of cells from bone marrow and other organs; and their native identity was recently confined into pericytes and adventitial cells in vascularized tissue. The multipotency, as well as the trophic and immunosuppressive effects, of MSCs have prompted the rapid development of clinical applications for many diseases involving tissue inflammation and immune disorders, including inflammatory bowel disease...
March 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28398563/studying-microstructure-and-microstructural-changes-in-plant-tissues-by-advanced-diffusion-magnetic-resonance-imaging-techniques
#11
Darya Morozov, Iris Tal, Odelia Pisanty, Eilon Shani, Yoram Cohen
As sessile organisms, plants must respond to the environment by adjusting their growth and development. Most of the plant body is formed post-embryonically by continuous activity of apical and lateral meristems. The development of lateral adventitious roots is a complex process, and therefore the development of methods that can visualize, non-invasively, the plant microstructure and organ initiation that occur during growth and development is of paramount importance. In this study, relaxation-based and advanced diffusion magnetic resonance imaging (MRI) methods including diffusion tensor (DTI), q-space diffusion imaging (QSI), and double-pulsed-field-gradient (d-PFG) MRI, at 14...
April 8, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28386609/a-family-of-rhodium-and-iridium-complexes-with-semirigid-benzylsilyl-phosphines-from-bidentate-to-tetradentate-coordination-modes
#12
María Vicky Corona-González, Julio Zamora-Moreno, Cynthia A Cuevas-Chávez, Ernesto Rufino-Felipe, Emmanuelle Mothes-Martin, Yannick Coppel, Miguel A Muñoz-Hernández, Laure Vendier, Marcos Flores-Alamo, Mary Grellier, Sylviane Sabo-Etienne, Virginia Montiel-Palma
The synthesis of a new trisbenzylsilanephosphine P{(o-C6H4CH2)SiMe2H}3 (1) is shown to proceed with high yields from P(o-tolyl)3. Compound 1 coordinates to the Rh and Ir dimers [MCl(COD)]2 (M = Rh, Ir) in a tetradentate or tridentate fashion, depending on the strict exclusion of water. The dimeric compounds [ClM(SiMe2CH2-o-C6H4)2P(o-C6H4-CH2SiMe2H)]2, 2Rh and 2Ir, feature a tetradentate coordination of the starting ligand with P and two Si atoms as well as a non-classical agostic Si-H group. The presence of adventitious water in the solvents leads to the formation of two new complexes [(μ(2)-Cl)2M2(SiMe2CH2-o-C6H4)2P(o-C6H4-CH2SiMe2OSiMe2CH2-o-C6H4-)P(SiMe2CH2-o-C6H4)2], 3Rh and 3Ir, which feature a siloxane bridge through Si-H bond breaking in 2...
April 7, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28381278/reciprocal-transplants-support-a-plasticity-first-scenario-during-colonisation-of-a-large-hyposaline-basin-by-a-marine-macro-alga
#13
Daniel Johansson, Ricardo T Pereyra, Marina Rafajlović, Kerstin Johannesson
BACKGROUND: Establishing populations in ecologically marginal habitats may require substantial phenotypic changes that come about through phenotypic plasticity, local adaptation, or both. West-Eberhard's "plasticity-first" model suggests that plasticity allows for rapid colonisation of a new environment, followed by directional selection that develops local adaptation. Two predictions from this model are that (i) individuals of the original population have high enough plasticity to survive and reproduce in the marginal environment, and (ii) individuals of the marginal population show evidence of local adaptation...
April 5, 2017: BMC Ecology
https://www.readbyqxmd.com/read/28378165/correlation-of-wall-microstructure-and-heterogeneous-distributions-of-strain-in-evolving-murine-abdominal-aortic-aneurysms
#14
John S Wilson, Matthew R Bersi, Guangxin Li, Jay D Humphrey
A primary deficiency in predicting the progression and rupture-risk of abdominal aortic aneurysms (AAAs) is an inability to assign patient-specific, heterogeneous biomechanical properties to the remodelling aortic wall. Toward this end, we investigated possible correlations between three quantities having the potential for non-invasive measurement (diameter, wall thickness, and strain) and local wall microstructure within evolving experimental AAAs. AAAs were initiated in male C57BL/6J mice via in situ adventitial application of elastase and allowed to progress for 1-4 weeks...
April 4, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28377589/the-arabidopsis-cop9-signalosome-subunit-4-cns4-is-involved-in-adventitious-root-formation
#15
Daniel Ioan Pacurar, Monica Lacramioara Pacurar, Abdellah Lakehal, Andrea Mariana Pacurar, Alok Ranjan, Catherine Bellini
The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins involved in many developmental and physiological processes, including light and hormone signaling and cell division. As a consequence of CSN pleiotropic function, complete loss of CSN activity results in seedling lethality...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28377273/biotechnological-production-of-hyperforin-for-pharmaceutical-formulation
#16
REVIEW
Mariam Gaid, Eline Biedermann, Jendrik Füller, Paul Haas, Sönke Behrends, Rainer Krull, Stephan Scholl, Ute Wittstock, Christel Müller-Goymann, Ludger Beerhues
Hyperforin is a major active constituent of Hypericum perforatum (St. John's wort). It has amazing pharmacological activities, such as antidepressant properties, but it is labile and difficult to synthesize. Its sensitivity and lipophilicity are challenges for processing and formulation. Its chemical complexity provokes approaches of biotechnological production and modification. Dedifferentiated H. perforatum cell cultures lack appropriate storage sites and hence appreciable hyperforin levels. Shoot cultures are capable of forming hyperforin but less suitable for biomass up-scaling in bioreactors...
April 2, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28366627/metagenomic-assessment-of-adventitious-viruses-in-commercial-bovine-sera
#17
Kathy Toohey-Kurth, Samuel D Sibley, Tony L Goldberg
Animal serum is an essential supplement for cell culture media. Contamination of animal serum with adventitious viruses has led to major regulatory action and product recalls. We used metagenomic methods to detect and characterize viral contaminants in 26 bovine serum samples from 12 manufacturers. Across samples, we detected sequences with homology to 20 viruses at depths of up to 50,000 viral reads per million. The viruses detected represented nine viral families plus four taxonomically unassigned viruses and had both RNA genomes and DNA genomes...
March 30, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28365837/comparison-of-phytohormone-levels-and-transcript-profiles-during-seasonal-dormancy-transitions-in-underground-adventitious-buds-of-leafy-spurge
#18
Wun S Chao, Münevver Doğramacı, David P Horvath, James V Anderson, Michael E Foley
Leafy spurge (Euphorbia esula L.) is an herbaceous perennial weed that maintains its perennial growth habit through generation of underground adventitious buds (UABs) on the crown and lateral roots. These UABs undergo seasonal phases of dormancy under natural conditions, namely para-, endo-, and ecodormancy in summer, fall, and winter, respectively. These dormancy phases can also be induced in growth chambers by manipulating photoperiod and temperature. In this study, UABs induced into the three phases of dormancy under controlled conditions were used to compare changes in phytohormone and transcriptome profiles...
April 1, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28362874/plasma-complement-and-vascular-complement-deposition-in-patients-with-coronary-artery-disease-with-and-without-inflammatory-rheumatic-diseases
#19
Kelly J Shields, Tom Eirik Mollnes, Jon Roger Eidet, Knut Mikkelsen, Sven M Almdahl, Barbara Bottazzi, Torstein Lyberg, Susan Manzi, Joseph M Ahearn, Ivana Hollan
PURPOSE: Inflammatory rheumatic diseases (IRD) are associated with accelerated coronary artery disease (CAD), which may result from both systemic and vascular wall inflammation. There are indications that complement may be involved in the pathogenesis of CAD in Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). This study aimed to evaluate the associations between circulating complement and complement activation products with mononuclear cell infiltrates (MCI, surrogate marker of vascular inflammation) in the aortic media and adventitia in IRDCAD and non-IRDCAD patients undergoing coronary artery bypass grafting (CABG)...
2017: PloS One
https://www.readbyqxmd.com/read/28362495/mechanistic-studies-on-a-cu-catalyzed-asymmetric-allylic-alkylation-with-cyclic-racemic-starting-materials
#20
Emeline Rideau, Hengzhi You, Mireia Sidera, Timothy D W Claridge, Stephen P Fletcher
Mechanistic studies on Cu-catalyzed asymmetric additions of alkylzirconocene nucleophiles to racemic allylic halide electrophiles were conducted using a combination of isotopic labeling, NMR spectroscopy, kinetic modeling, structure-activity relationships, and new reaction development. Kinetic and dynamic NMR spectroscopic studies provided insight into the oligomeric Cu-ligand complexes, which evolve during the course of the reaction to become faster and more highly enantioselective. The Cu-counterions play a role in both selecting different pathways and in racemizing the starting material via formation of an allyl iodide intermediate...
April 10, 2017: Journal of the American Chemical Society
keyword
keyword
20938
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"