keyword
MENU ▼
Read by QxMD icon Read
search

Carms

keyword
https://www.readbyqxmd.com/read/28427527/venous-thromboembolism-in-radiation-therapy-cancer-patients-findings-from-the-riete-registry
#1
REVIEW
Jean-Baptiste Guy, Laurent Bertoletti, Nicolas Magné, Chloé Rancoule, Isabelle Mahé, Carme Font, Oscar Sanz, José Manuel Martín-Antorán, Federica Pace, Jerónimo Ramón Vela, Manuel Monreal
BACKGROUND: Cancer patients are at high risk of venous thromboembolism, particularly during cancer treatment. Conversely to chemotherapy, data on the epidemiology and clinical features of venous thromboembolism during radiation therapy are scarce. There is lack of evidence on the influence of radiation therapy (RT) on outcome in cancer patients with acute venous thromboembolism (VTE). METHODS: We used the RIETE (Registro Informatizado de Enfermedad ThromboEmbolica) database to assess the clinical characteristics and outcome of prospectively-collected consecutive patients with cancer-associated thrombosis occurred during the course of radiation therapy for cancer...
May 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28423537/limitations-in-predicting-pam50-intrinsic-subtype-and-risk-of-relapse-score-with-ki67-in-estrogen-receptor-positive-her2-negative-breast-cancer
#2
Aranzazu Fernandez-Martinez, Tomás Pascual, Giuseppe Perrone, Serafin Morales, Juan de la Haba, Milagros González-Rivera, Patricia Galván, Francesca Zalfa, Michela Amato, Lucia Gonzalez, Miquel Prats, Federico Rojo, Luis Manso, Laia Paré, Immaculada Alonso, Joan Albanell, Ana Vivancos, Antonio González, Judit Matito, Sonia González, Pedro Fernandez, Barbara Adamo, Montserrat Muñoz, Margarita Viladot, Carme Font, Francisco Aya, Maria Vidal, Rosalía Caballero, Eva Carrasco, Vittorio Altomare, Giuseppe Tonini, Aleix Prat, Miguel Martin
PAM50/Prosigna gene expression-based assay identifies three categorical risk of relapse groups (ROR-low, ROR-intermediate and ROR-high) in post-menopausal patients with estrogen receptor estrogen receptor-positive (ER+)/ HER2-negative (HER2-) early breast cancer. Low risk patients might not need adjuvant chemotherapy since their risk of distant relapse at 10-years is below 10% with endocrine therapy only. In this study, 517 consecutive patients with ER+/HER2- and node-negative disease were evaluated for Ki67 and Prosigna...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28420394/influence-maternal-background-has-on-children-s-mental-health
#3
Elena Arroyo-Borrell, Gemma Renart, Carme Saurina, Marc Saez
BACKGROUND: In this paper, we aim to discern how a mother's health and her socioeconomic determinants may influence her children's mental health. In addition to this, we also evaluate the influence of other household characteristics and whether or not the economic downturn has heightened the effect a parent's social gradient has on their children's mental health. METHODS: We use samples comprised of 4-14-year-old minors from the 2006 Spanish National Health Survey (SNHS), undertaken prior to the crisis, and the 2011 SNHS, carried out during the crisis...
April 18, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28419282/autologous-hematopoietic-stem-cell-transplantation-for-refractory-crohn-s-disease-efficacy-in-a-single-centre-cohort
#4
Alicia López-García, Montserrat Rovira, Aranzazu Jauregui-Amezaga, Pedro Marín, Rebeca Barastegui, Azucena Salas, Vicent Ribas, Faust Feu, J Ignasi Elizalde, Francesc Fernández-Avilés, Carmen Martínez, Gonzalo Gutiérrez, Laura Rosiñol, Enric Carreras, Alvaro Urbano, Miguel Lozano, Joan Cid, Maria Suárez-Lledó, Maria Carme Masamunt, Dolors Comas, Angel Giner, Marta Gallego, Ignacio Alfaro, Ingrid Ordás, Julian Panés, Elena Ricart
Background: Hematopoietic stem cell transplantation (HSCT) is considered a therapeutic option for patients with severe Crohn's disease (CD) unresponsive to currently available therapies. Methods: Autologous HSCT was considered for CD patients with active disease, unresponsive or intolerant to approved medications and unsuitable for surgery. After HSCT, patients were closely followed-up every 6 weeks during the first 2 years and every 6 months thereafter up to 5 years...
April 13, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28410797/-infobarris-an-interactive-tool-to-monitor-and-disseminate-information-on-health-and-its-determinants-in-the-neighbourhoods-of-barcelona-spain
#5
Pere Llimona, Glòria Pérez, Maica Rodríguez-Sanz, Ana M Novoa, Albert Espelt, Patricia Garcia de Olalla, Carme Borrell
In order to know about the health of the population, it is necessary to perform a systematic and continuous analysis of their health status and social and economic health determinants. The objective of this paper is to describe the development and implementation of the Infobarris tool, which allows to visualize a wide battery of indicators and social determinants of health by neighbourhoods in the city of Barcelona (Spain). For the development of the Infobarris tool, we used an agile methodology that allows the development of a project in iterative and incremental stages, which are the following: selection of indicators, design of the prototype, development of the tool, data loading, and tool review and improvements...
April 11, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28409923/the-catalase-activity-of-catalase-peroxidases-is-modulated-by-changes-in-the-pka-of-the-distal-histidine
#6
Miguel Machuqueiro, Bruno Victor, Jacek Switala, Jacylyn Villanueva, Carme Rovira, Ignacio Fita, Peter C Loewen
The unusual Met-Tyr-Trp adduct composed of cross-linked side chains along with an associated mobile Arg is essential for catalase activity in catalase-peroxidases. In addition, acidic residues in the entrance channel, in particular an Asp and a Glu ∼7 and ∼15 Å, respectively, from the heme, significantly enhance catalase activity. The mechanism by which these channel carboxylates influence catalase activity is the focus of this work. Seventeen new variants with fewer and additional acidic residues have been constructed and characterized structurally and for enzymatic activity, revealing that their effect on activity is roughly inversely proportional to their distance from the heme and adduct, suggesting that the electrostatic potential of the heme cavity may be affected...
April 20, 2017: Biochemistry
https://www.readbyqxmd.com/read/28409152/the-association-between-imaging-parameters-of-the-paraspinal-muscles-spinal-degeneration-and-low-back-pain
#7
REVIEW
Leonid Kalichman, Eli Carmeli, Ella Been
This narrative review investigated imaging parameters of the paraspinal muscles and their association with spinal degenerative features and low back pain (LBP) found in the literature. Three principal signs of muscle degeneration were detected on imaging: decreased muscle size, decreased radiographic density, and increased fat deposits. Men have a higher density of paraspinal muscles than women, younger individuals have a higher density than older ones, and lean individuals have a higher density than those with an increased body mass index...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28401047/neuroimaging-studies-of-cognitive-remediation-in-schizophrenia-a-systematic-and-critical-review
#8
Rafael Penadés, Alexandre González-Rodríguez, Rosa Catalán, Bàrbara Segura, Miquel Bernardo, Carme Junqué
AIM: To examine the effects of cognitive remediation therapies on brain functioning through neuroimaging procedures in patients with schizophrenia. METHODS: A systematic, computerised literature search was conducted in the PubMed/Medline and PsychInfo databases. The search was performed through February 2016 without any restrictions on language or publication date. The search was performed using the following search terms: [("cogniti*" and "remediation" or "training" or "enhancement") and ("fMRI" or "MRI" or "PET" or "SPECT") and (schizophrenia or schiz*)]...
March 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/28392634/a-new-concept-for-measuring-leg-length-discrepancy
#9
Sam Khamis, Eli Carmeli
No abstract text is available yet for this article.
June 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28390183/cytocompatibility-assessment-of-ti-zr-pd-si-nb-alloys-with-low-young-s-modulus-increased-hardness-and-enhanced-osteoblast-differentiation-for-biomedical-applications
#10
Andreu Blanquer, Jana Musilkova, Leonardo Barrios, Elena Ibáñez, Marta Vandrovcova, Eva Pellicer, Jordi Sort, Lucie Bacakova, Carme Nogués
Ti-based alloys have increased importance for biomedical applications due to their excellent properties. In particular, the two recently developed TiZrPdSi(Nb) alloys, with a predominant β-Ti phase microstructure, have good mechanical properties, such as a relatively low Young's modulus and high hardness. In the present work, the cytocompatibility of these alloys was assessed using human osteoblast-like Saos-2 cells. Cells grown on the alloys showed larger spreading areas (more than twice) and higher vinculin content (nearly 40% increment) when compared with cells grown on glass control surfaces, indicating a better cell adhesion...
April 8, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28382607/frailty-and-primary-sarcopenia-a-review
#11
Eli Carmeli
Increasing longevity, coupled with rising frailty and sarcopenia of aging, significantly affects function and quality of life of older adults. This review discusses the definition, assessment, and management of frailty and sarcopenia, and examines the relationship between them. Medline, Scopus and Psychoinfo databases were searched using the keywords frailty, sarcopenia, aging, and functional disability. The findings are that frailty and sarcopenia are often assessed clinically with such methods such as DeXA, CT scan, MRI, bioelectrical impedance, or anthropometry...
April 6, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28380353/interaction-dynamics-determine-signaling-and-output-pathway-responses
#12
Klement Stojanovski, Tony Ferrar, Hannah Benisty, Friedemann Uschner, Javier Delgado, Javier Jimenez, Carme Solé, Eulalia de Nadal, Edda Klipp, Francesc Posas, Luis Serrano, Christina Kiel
The understanding of interaction dynamics in signaling pathways can shed light on pathway architecture and provide insights into targets for intervention. Here, we explored the relevance of kinetic rate constants of a key upstream osmosensor in the yeast high-osmolarity glycerol-mitogen-activated protein kinase (HOG-MAPK) pathway to signaling output responses. We created mutant pairs of the Sln1-Ypd1 complex interface that caused major compensating changes in the association (kon) and dissociation (koff) rate constants (kinetic perturbations) but only moderate changes in the overall complex affinity (Kd)...
April 4, 2017: Cell Reports
https://www.readbyqxmd.com/read/28370234/enumerating-bone-marrow-blasts-from-nonerythroid-cellularity-improves-outcome-prediction-in-myelodysplastic-syndromes-and-permits-a-better-definition-of-the-intermediate-risk-category-of-the-revised-international-prognostic-scoring-system-ipss-r
#13
Xavier Calvo, Leonor Arenillas, Elisa Luño, Leonor Senent, Montserrat Arnan, Fernando Ramos, Carme Pedro, Mar Tormo, Julia Montoro, María Díez-Campelo, María Laura Blanco, Beatriz Arrizabalaga, Blanca Xicoy, Santiago Bonanad, Andrés Jerez, Meritxell Nomdedeu, Ferrer Ana, Guillermo F Sanz, Lourdes Florensa
The Revised International Prognostic Scoring System (IPSS-R) has been recognized as the score with the best outcome prediction capability in MDS, but this brought new concerns about the accurate prognostication of patients classified into the intermediate risk category. The correct enumeration of blasts is essential in prognostication of MDS. Recent data evidenced that considering blasts from nonerythroid cellularity (NECs) improves outcome prediction in the context of IPSS and WHO classification. We assessed the percentage of blasts from total nucleated cells (TNCs) and NECs in 3,924 MDS patients from the GESMD, 498 of whom were MDS with erythroid predominance (MDS-E)...
March 28, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28349948/discriminating-cognitive-status-in-parkinson-s-disease-through-functional-connectomics-and-machine-learning
#14
Alexandra Abós, Hugo C Baggio, Bàrbara Segura, Anna I García-Díaz, Yaroslau Compta, Maria José Martí, Francesc Valldeoriola, Carme Junqué
There is growing interest in the potential of neuroimaging to help develop non-invasive biomarkers in neurodegenerative diseases. In this study, connection-wise patterns of functional connectivity were used to distinguish Parkinson's disease patients according to cognitive status using machine learning. Two independent subject samples were assessed with resting-state fMRI. The first (training) sample comprised 38 healthy controls and 70 Parkinson's disease patients (27 with mild cognitive impairment). The second (validation) sample included 25 patients (8 with mild cognitive impairment)...
March 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28346335/apparent-interfacial-tension-effects-in-protein-stabilized-emulsions-prepared-with-microstructured-systems
#15
Carme Güell, Montserrat Ferrando, Alexandre Trentin, Karin Schroën
Proteins are mostly used to stabilize food emulsions; however, production of protein containing emulsions is notoriously difficult to capture in scaling relations due to the complex behavior of proteins in interfaces, in combination with the dynamic nature of the emulsification process. Here, we investigate premix membrane emulsification and use the Ohnesorge number to derive a scaling relation for emulsions prepared with whey protein, bovine serum albumin (BSA), and a standard emulsifier Tween 20, at various concentrations (0...
March 25, 2017: Membranes
https://www.readbyqxmd.com/read/28334623/rapid-on-chip-apoptosis-assay-on-human-carcinoma-cells-based-on-annexin-v-quantum-dot-probes
#16
Helena Montón, Mariana Medina-Sánchez, Joan Antoni Soler, Andrzej Chałupniak, Carme Nogués, Arben Merkoçi
Despite all the efforts made over years to study the cancer expression and the metastasis event, there is not a clear understanding of its origins and effective treatment. Therefore, more specialized and rapid techniques are required for studying cell behaviour under different drug-based treatments. Here we present a quantum dot signalling-based cell assay carried out in a segmental microfluidic device that allows studying the effect of anti-cancer drugs in cultured cell lines by monitoring phosphatidylserine translocation that occurs in early apoptosis...
March 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28328090/bronchiolitis-score-of-sant-joan-de-d%C3%A3-u-brosjod-score-validation-and-usefulness
#17
Mònica Balaguer, Carme Alejandre, David Vila, Elisabeth Esteban, Josep L Carrasco, Francisco José Cambra, Iolanda Jordan
OBJECTIVE: To validate the bronchiolitis score of Sant Joan de Déu (BROSJOD) and to examine the previously defined scoring cutoff. PATIENTS AND METHODS: Prospective, observational study. BROSJOD scoring was done by two independent physicians (at admission, 24 and 48 hr). Internal consistency of the score was assessed using Cronbach's α. To determine inter-rater reliability, the concordance correlation coefficient estimated as an intraclass correlation coefficient (CCC) and limits of agreement estimated as the 90% total deviation index (TDI) were estimated...
April 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28327501/accurate-determination-of-the-frequency-response-function-of-submerged-and-confined-structures-by-using-pzt-patches%C3%A2
#18
Alexandre Presas, David Valentin, Eduard Egusquiza, Carme Valero, Mònica Egusquiza, Matias Bossio
To accurately determine the dynamic response of a structure is of relevant interest in many engineering applications. Particularly, it is of paramount importance to determine the Frequency Response Function (FRF) for structures subjected to dynamic loads in order to avoid resonance and fatigue problems that can drastically reduce their useful life. One challenging case is the experimental determination of the FRF of submerged and confined structures, such as hydraulic turbines, which are greatly affected by dynamic problems as reported in many cases in the past...
March 22, 2017: Sensors
https://www.readbyqxmd.com/read/28325776/noninvasive-respiratory-support-during-pediatric-ground-transport-implementation-of-a-safe-and-feasible-procedure
#19
Nuria Millán, Carme Alejandre, Aina Martinez-Planas, Josep Caritg, Elisabeth Esteban, Martí Pons-Òdena
BACKGROUND: The purpose of this work was to determine the safety and feasibility of noninvasive support in children with acute respiratory failure (ARF) during interhospital ground transport. METHODS: This was a prospective, single-center observational clinical study in the pediatric transport unit of a tertiary-care pediatric hospital. We included all subjects with ARF transported from November 2010 to March 2013. A specific noninvasive support protocol was used for all cases...
March 21, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28314812/improvement-in-arm-and-hand-function-after-a-stroke-with-task-oriented-training
#20
Sharon Israely, Gerry Leisman, Eli Carmeli
A man aged 77 years sustained a left-hemisphere stroke with right hemiparesis. After spending 10 days in the hospital, he was referred to an area rehabilitation centre. There he carried out daily physical, occupational and speech therapy, with an emphasis on task-oriented treatment. The patient's upper-extremity motor performance was evaluated at admission to the rehabilitation centre and before leaving the hospital by 3 different measurement tools: the upper-extremity motor part of the Fugl-Meyer assessment scale, electromyography in hand-reach and grasp and object manipulation and handwriting tasks...
March 17, 2017: BMJ Case Reports
keyword
keyword
20932
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"