Pere Godoy, Iván Martínez-Baz, Ignasi Parron, Manuel García-Cenoz, Joaquim Ferras, Mònica Carol, Nuria Bes, Montserrat Guillaumes, Sofia Godoy, Diana Toledo, Núria Follia, Carme Miret, Jessica Pardos, Miquel Alsedà, Pedro Plans-Rubio, Inma Sanz, Maria-Rosa Sala, Joan A Caylà, Jacobo Mendioroz, Carmen Muñoz-Almagro, Jesús Castilla, Ángela Domínguez, On Behalf Of The Sars-CoV-Transmission To Household Contacts Working Group
The aim of this study was to evaluate the impact of index case vaccination on SARS-CoV-2 transmission to household contacts. In our epidemiological cohort study (May 2022-November 2023), we surveyed registered index case vaccination status and test results for contacts (testing on day 0, and on day 7 for negative contacts) and calculated the secondary attack rate (SAR), i.e., newly infected contacts/susceptible included contacts. The association of the independent variable, index case COVID-19 vaccination (yes/no), with household contact infection was determined using the adjusted odds ratio (aOR) and its 95% confidence interval (CI)...
February 26, 2024: Vaccines