keyword
https://read.qxmd.com/read/38497221/evaluation-of-a-training-program-on-gender-mainstreaming-in-health-research-evaluation-at-the-senegalese-national-research-ethics-committee
#1
JOURNAL ARTICLE
Guillermo Z Martínez-Pérez, Carme Campoy Guerrero, Brigitte Bagnol, Samba Cor Sarr, El Hadji Mamadou Mbaye, Ousmane Diouf, El Hadji Ibrahima Touré, Viviane Mbengue, Oumy Ndiaye, Farah Nabil
Health research must be of high ethical and scientific quality and consider the needs and experiences of women, men, and nonbinary individuals. National Research Ethics Committees (RECs) are in a strategic position to impede sex- and gender-blind research. In 2020 and 2021, training programs on gender mainstreaming and sex and gender approaches in research evaluation were launched in Senegal. They were evaluated through a mixture of qualitative and quantitative methods. Knowledge acquisition was 16.67%, 8.54%, and 28...
March 18, 2024: Journal of Empirical Research on Human Research Ethics: JERHRE
https://read.qxmd.com/read/38491341/a-permissible-sin-perceptions-of-smoking-among-haredi-men-in-israel
#2
JOURNAL ARTICLE
Shlomo Guzmen-Carmeli, Rotem Weizman, Tammar Friedman
This essay deals with perceptions of smoking among Haredi men in Israel. Though trends in smoking within the Haredi society have been quantitively examined, no qualitative research has ever focused on the motivations and mindsets stimulating individuals' choices to take health risks despite religious precepts to the contrary. Israeli Haredi men sometimes start smoking in their early childhood and are unmotivated to quit, and such circumstances should be examined. We interviewed 20 Israeli Haredi male smokers and overviewed the Haredi daily press and rabbinical attitudes toward smoking...
March 15, 2024: Journal of Religion and Health
https://read.qxmd.com/read/38490910/it-s-not-all-ingrowing-nail-childhood-retronychia
#3
JOURNAL ARTICLE
Cristina Nogueroles Blanco, Sara Fuentes Carretero, Carme Grande Moreillo, Jaume Margarit Mallol
No abstract text is available yet for this article.
March 14, 2024: Anales de pediatría
https://read.qxmd.com/read/38485101/a-meta-analysis-of-potential-biomarkers-associated-with-microplastic-ingestion-in-marine-fish
#4
REVIEW
Montserrat Compa, Xavier Capó, Carme Alomar, Salud Deudero, Antoni Sureda
Over the past decade, global reports have shown a rise in the harmful effects of microplastics (MPs) on marine fish. This study analysed marine species' biochemical biomarker responses to microplastic exposure, finding that MPs can induce oxidative stress in marine fish through meta-regression results. Overall, exposure to MPs resulted in the activation of antioxidant defence mechanisms, such as superoxide dismutase, catalase and glutathione reductase, detoxification enzymes such as glutathione-S-transferase, the detection of malondialdehyde, and inhibition of acetylcholinesterase...
March 12, 2024: Environmental Toxicology and Pharmacology
https://read.qxmd.com/read/38477635/lived-experiences-of-mental-health-nurses-who-care-for-clients-who-are-parents-an-approximation-of-tronto-s-definition-of-care
#5
JOURNAL ARTICLE
Judit Vives-Espelta, Laura Ortega-Sanz, Carme Ferré-Grau, Maria-Dolors Burjalés-Martí
WHAT IS KNOWN ON THE SUBJECT: Adult psychiatric services typically focus on the mental health needs of the client but they do not support his or her parenting role. Many authors highlight the importance of a non-judgmental approach when providing support and care to clients with mental illness who are parents. Assessments frequently focus on the negative aspects while the strengths of these families were often overlooked. There is a lack of scientific literature exploring nurses' experiences when caring for parents with mental illness and their families...
March 13, 2024: Journal of Psychiatric and Mental Health Nursing
https://read.qxmd.com/read/38476953/-zophobas-morio-larvae-as-a-novel-model-for-the-study-of-acinetobacter-virulence-and-antimicrobial-resistance
#6
JOURNAL ARTICLE
Nadya Rakovitsky, Elizabeth Temkin, Amichay Hameir, Mor Lurie-Weinberger, Alona Keren-Paz, Yehuda Carmeli
The use of mammalian models for in vivo testing of bacterial virulence raises ethical concerns and is expensive and time-consuming. As an alternative, non-mammalian models are sought. Galleria mellonella larvae have been used as a model to study several bacterial pathogens. However, their maintenance is challenging, and commercial supply is low. In this study, we aimed to establish the Zophobas morio larvae as an alternative non-mammalian model for the evaluation of the pathogenicity and antimicrobial susceptibility of Acinetobacter baumannii ...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38475185/sons-al-balc%C3%A3-a-comparative-analysis-of-wasn-based-l-aeq-measured-values-with-perceptual-questionnaires-in-barcelona-during-the-covid-19-lockdown
#7
JOURNAL ARTICLE
Daniel Bonet-Solà, Pau Bergadà, Enric Dorca, Carme Martínez-Suquía, Rosa Ma Alsina-Pagès
The mobility and activity restrictions imposed in Spain due to the COVID-19 pandemic caused a significant improvement in the urban noise pollution that could be objectively measured in those cities with acoustic sensor networks deployed. This significant change in the urban soundscapes was also perceived by citizens who positively appraised this new acoustic scenario. In this work, authors present a comparative analysis between different noise indices provided by 70 sound sensors deployed in Barcelona, both during and before the lockdown, and the results of a perceptual test conducted in the framework of the project Sons al Balcó during the lockdown, which received more than one hundred contributions in Barcelona alone...
March 3, 2024: Sensors
https://read.qxmd.com/read/38457055/correction-reference-values-of-eortc-qlq-c30-eortc-qlq-br23-and-eq-5d-5l-for-women-with-non-metastatic-breast-cancer-at-diagnosis-and-2-years-after
#8
Carme Miret, Miren Orive, Maria Sala, Susana García-Gutiérrez, Cristina Sarasqueta, Maria Jose Legarreta, Maximino Redondo, Amado Rivero, Xavier Castells, José M Quintana, Olatz Garin, Montse Ferrer
No abstract text is available yet for this article.
March 8, 2024: Quality of Life Research
https://read.qxmd.com/read/38456361/cortical-macro-and-microstructural-changes-in-parkinson-s-disease-with-probable-rapid-eye-movement-sleep-behavior-disorder
#9
JOURNAL ARTICLE
Jèssica Pardo, Victor Montal, Anna Campabadal, Javier Oltra, Carme Uribe, Ignacio Roura, Núria Bargalló, Maria J Martí, Yaroslau Compta, Alex Iranzo, Juan Fortea, Carme Junqué, Bàrbara Segura
BACKGROUND: Evidence regarding cortical atrophy patterns in Parkinson's disease (PD) with probable rapid eye movement sleep behavior disorder (RBD) (PD-pRBD) remains scarce. Cortical mean diffusivity (cMD), as a novel imaging biomarker highly sensitive to detecting cortical microstructural changes in different neurodegenerative diseases, has not been investigated in PD-pRBD yet. OBJECTIVES: The aim was to investigate cMD as a sensitive measure to identify subtle cortical microstructural changes in PD-pRBD and its relationship with cortical thickness (CTh)...
March 8, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38452909/being-fit-in-the-covid-19-era-and-future-epidemics-prevention-importance-of-cardiopulmonary-exercise-test-in-fitness-evaluation
#10
REVIEW
Fernando de la Guía-Galipienso, Patricia Palau, Alejandro Berenguel-Senen, Carme Perez-Quilis, Jeffrey W Christle, Jonathan Myers, François Haddad, Aaron Baggish, Flavio D'Ascenzi, Carl J Lavie, Giuseppe Lippi, Fabian Sanchis-Gomar
Endurance and resistance physical activity have been shown to stimulate the production of immunoglobulins and boost the levels of anti-inflammatory cytokines, natural killer cells, and neutrophils in the bloodstream, thereby strengthening the ability of the innate immune system to protect against diseases and infections. Coronavirus disease 19 (COVID-19) greatly impacted people's cardiorespiratory fitness (CRF) and health worldwide. Cardiopulmonary exercise testing (CPET) remains valuable in assessing physical condition, predicting illness severity, and guiding interventions and treatments...
March 5, 2024: Progress in Cardiovascular Diseases
https://read.qxmd.com/read/38450188/targeted-therapy-or-immunotherapy-in-braf-mutated-metastatic-melanoma-a-spanish-center-s-decade-of-experience
#11
JOURNAL ARTICLE
Chen Sun, Sofia España, Nina Richarz, Carme Solé-Blanch, Aram Boada, Anna Martinez-Cardús, Alan Chu, Zongwen Liu, Jose Luis Manzano
BACKGROUND: Targeted therapies and immunotherapy are currently considered the mainstay first-line treatment for advanced BRAF-mutated melanoma. However, the impact of treatment (targeted therapy and immunotherapy) and the prognostic factors are still not clear. MATERIAL AND METHODS: Medical records of 140 patients diagnosed with advanced melanoma between 2011 and 2021 were retrospectively reviewed to extract demographic, BRAF status, treatment, performance status, and survival data...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38449530/evolution-of-phosphorylase-activity-in-an-ancestral-glycosyltransferase
#12
JOURNAL ARTICLE
Jorick Franceus, José Pablo Rivas-Fernández, Jolien Lormans, Carme Rovira, Tom Desmet
The reconstruction of ancestral sequences can offer a glimpse into the fascinating process of molecular evolution by exposing the adaptive pathways that shape the proteins found in nature today. Here, we track the evolution of the carbohydrate-active enzymes responsible for the synthesis and turnover of mannogen, a critical carbohydrate reserve in Leishmania parasites. Biochemical characterization of resurrected enzymes demonstrated that mannoside phosphorylase activity emerged in an ancestral bacterial mannosyltransferase, and later disappeared in the process of horizontal gene transfer and gene duplication in Leishmania ...
March 1, 2024: ACS Catalysis
https://read.qxmd.com/read/38449032/male-genitourinary-schistosomiasis-related-symptoms-among-long-term-western-african-migrants-in-spain-a-prospective-population-based-screening-study
#13
JOURNAL ARTICLE
Sílvia Roure, Xavier Vallès, Olga Pérez-Quílez, Israel López-Muñoz, Anna Chamorro, Elena Abad, Lluís Valerio, Laura Soldevila, Sergio España, Alaa H A Hegazy, Gema Fernández-Rivas, Ester Gorriz, Dolores Herena, Mário Oliveira, Maria Carme Miralles, Carmen Conde, Juan José Montero-Alia, Elia Fernández-Pedregal, Jose Miranda-Sánchez, Josep M Llibre, Mar Isnard, Josep Maria Bonet, Oriol Estrada, Núria Prat, Bonaventura Clotet
BACKGROUND: Schistosomiasis is highly endemic in sub-Saharan Africa and frequently imported to Europe. Male urogenital manifestations are often neglected. We aimed to ascertain the prevalence of genitourinary clinical signs and symptoms among long-term African migrants in a non-endemic European country using a serology test. METHODS: We carried out a prospective, community-based cross-sectional study of adult male migrants from sub-Saharan Africa living in Spain...
March 7, 2024: Infectious Diseases of Poverty
https://read.qxmd.com/read/38447961/the-natural-history-of-carbapenemase-producing-enterobacterales-progression-from-carriage-of-various-carbapenemases-to-bloodstream-infection
#14
JOURNAL ARTICLE
Elizabeth Temkin, Ester Solter, Carmela Lugassy, Dafna Chen, Adi Cohen, Mitchell J Schwaber, Yehuda Carmeli
BACKGROUND: Little is known about the risk of progression from carbapenemase-producing Enterobacterales (CPE) carriage to CPE bloodstream infection (BSI) outside of high-risk settings. We aimed to determine the incidence of CPE BSI among CPE carriers and to assess whether the incidence differed by carbapenemase, species, and setting. METHODS: We conducted a nationwide population-based retrospective cohort study using national databases. The cohort consisted of all patients in Israel with CPE detected by screening from 1/1/2020 to 10/10/2022...
March 6, 2024: Clinical Infectious Diseases
https://read.qxmd.com/read/38443238/the-prognostic-role-of-histomorphological-subtyping-in-nonmetastatic-papillary-renal-cell-carcinoma-after-curative-surgery-is-subtype-really-irrelevant-a-propensity-score-matching-analysis-of-a-multi-institutional-real-life-data
#15
JOURNAL ARTICLE
Selcuk Erdem, Riccardo Bertolo, Riccardo Campi, Umberto Capitanio, Daniele Amparore, Umberto Anceschi, Maria Carme Mir, Eduard Roussel, Nicola Pavan, Umberto Carbonara, Onder Kara, Tobias Klatte, Michele Marchioni, Angela Pecoraro, Stijn Muselaers, Laura Marandino, Pietro Diana, Leonardo Borregales, Carlotta Palumbo, Hannah Warren, Zhenjie Wu, Anna Calio, Chiara Ciccarese, Enes Degirmenci, Resat Aydin, Giacomo Rebez, Luigi Schips, Giuseppe Simone, Andrea Minervini, Sergio Serni, Faruk Ozcan
BACKGROUND AND AIM: The role of histomorphological subtyping is an issue of debate in papillary renal cell carcinoma (papRCC). This multi-institutional study investigated the prognostic role of histomorphological subtyping in patients undergoing curative surgery for nonmetastatic papRCC. PATIENTS AND METHODS: A total of 1,086 patients undergoing curative surgery were included from a retrospectively collected multi-institutional nonmetastatic papRCC database. The patients were divided into 2 groups based on histomorphological subtyping (type 1, n = 669 and type 2, n = 417)...
March 4, 2024: Urologic Oncology
https://read.qxmd.com/read/38430998/biophysical-evaluation-of-antiparallel-triplexes-for-biosensing-and-biomedical-applications
#16
JOURNAL ARTICLE
Arnau Domínguez, Raimundo Gargallo, Carlos Cuestas-Ayllón, Valeria Grazu, Carme Fàbrega, Simonas Valiuska, Véronique Noé, Carlos J Ciudad, Enrique J Calderon, Jesús Martínez de la Fuente, Ramon Eritja, Anna Aviñó
Polypyrimidine sequences can be targeted by antiparallel clamps forming triplex structures either for biosensing or therapeutic purposes. Despite its successful implementation, their biophysical properties remain to be elusive. In this work, PAGE, circular dichroism and multivariate analysis were used to evaluate the properties of PPRHs directed to SARS-CoV-2 genome. Several PPRHs designed to target various polypyrimidine sites within the viral genome were synthesized. These PPRHs displayed varying binding affinities, influenced by factors such as the length of the PPRH and its GC content...
February 29, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38426764/carbapenem-resistant-acinetobacter-baumannii-carrier-detection-a-simple-and-efficient-protocol
#17
JOURNAL ARTICLE
Jonathan Lellouche, Alona Keren-Paz, Reut Rov, Reut Efrati Epchtien, Sammy Frenk, Amichay Hameir, Elizabeth Temkin, David Schwartz, Yehuda Carmeli
UNLABELLED: Timely detection of carbapenem-resistant Acinetobacter baumannii (CRAB) carriers is essential to direct infection control measures. In this work, we aimed to develop a practical protocol to detect CRAB from screening samples. To choose a selective medium that detects CRAB with high sensitivity and specificity, 111 A . baumannii clinical isolates were inoculated on three types of agar: mSuperCARBA (SC), CHROMagar Acinetobacter (CaA), and modified CHROMagar Acinetobacter (mCaA) containing 4...
March 1, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38423314/screening-of-organic-chemicals-associated-to-virgin-low-density-polyethylene-microplastic-pellets-exposed-to-the-mediterranean-sea-environment-by-combining-gas-chromatography-and-liquid-chromatography-coupled-to-quadrupole-time-of-flight-mass-spectrometry
#18
JOURNAL ARTICLE
Javier López-Vázquez, Rosario Rodil, Elvira Álvarez, Carme Alomar, Rafael Cela, Manuel Miró, Salud Deudero, José Benito Quintana
In this work, organic chemicals associated with microplastics (MPs) exposed to a coastal anthropogenized environment for up to eight weeks have been screened for, in order to discern the (de)sorption dynamics of chemicals in the marine ecosystem. Low-density polyethylene (LDPE) pellets were studied since they represent primary MPs used by the plastic industry and a relevant input of MPs into the oceans. To maximize the coverage of chemicals that could be detected, both liquid and gas chromatography coupled to quadrupole-time-of-flight (GC-QTOF and LC-QTOF, respectively) were used...
February 27, 2024: Science of the Total Environment
https://read.qxmd.com/read/38417201/-initial-assessment-of-immigrant-patients-in-primary-care
#19
JOURNAL ARTICLE
María Ángeles González Martínez, María Jesús Castaño Suero, Marta Guerrero Muñoz, Agustín Francisco Rossetti, Ethel Sequeira Aymar, Carme Roca Saumell
The clinical interview of immigrant patients requires cultural competence to ensure good understanding and correct communication, in addition to collecting specific information that differs from that of native patients, such as origin and migratory route or cultural identity. Screening for latent tuberculosis infection is recommended in certain cases and screening for other infections, both cosmopolitan with a higher prevalence in migrants (HIV, syphilis, hepatitis B and C) and imported (Chagas, intestinal parasites, strongyloidiasis, schistosomiasis), depending on origin...
February 27, 2024: Atencion Primaria
https://read.qxmd.com/read/38415804/mechanical-stability-of-posterior-implant-supported-monolithic-zirconia-cantilever-on-titanium-base-abutments-an-in%C3%A2-vitro-study
#20
JOURNAL ARTICLE
Carme Riera, Duygu Karasan, Irena Sailer, Phillipe Mojon, Vincent Fehmer, João Pitta
PURPOSE: Investigate survival and technical complications of two-unit posterior implant-supported cantilever made of monolithic zirconia on titanium-base abutments (Zr-TiB) vs. porcelain-fused-to-metal on castable gold abutments (PFM-GA) using two different implant connections, internal butt-joint (IBJ) and internal conical (IC). MATERIALS AND METHODS: Forty-eight implants (4.3 mm diameter) were divided into four groups (n = 12) to support 2-unit mandibular premolar cantilevers with two different materials (Zr-TiB vs...
February 28, 2024: Clinical Oral Implants Research
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