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https://www.readbyqxmd.com/read/29350188/accurate-identification-of-layer-number-for-few-layer-ws2-and-wse2-via-spectroscopic-study
#1
Yuanzheng Li, Xinshu Li, Tong Yu, Guochun Yang, Heyu Chen, Cen Zhang, Qiushi Feng, Jiangang Ma, Weizhen Liu, Haiyang Xu, Yichun Liu, Xinfeng Liu
Transition metal dichalcogenides (TMDs) with typical layered structure are highly sensitive to their layer number in optical and electronic properties. Seeking a simple and effective method for layer number identification is very important to low-dimensional TMDs samples. Herein, a rapid and accurate layer number identification of few-layer WS2 and WSe2 is proposed via locking their photoluminescence (PL) peak-positions. As the layer number of WS2/WSe2 increases, it is found that indirect transition emission is more thickness-sensitive than direct transition emission, and the PL peak-position differences between the indirect and direct transitions can be regarded as fingerprints to identify their layer number...
January 19, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29347344/experimental-investigation-of-mesoscopic-heterogeneous-motion-of-laser-activated-self-propelling-janus-particles-in-suspension
#2
Chong-Wai Io, Tzu-Yin Chen, Jai-Wei Yeh, Sin-Cen Cai
The mesoscopic collective motion of self-propelling active particle suspension is experimentally investigated. The active particles are silica micro spheres with Au hemisphere coating, and their propelling strength is activated by laser irradiation. The suspension is driven from equilibrium to near equilibrium and far from equilibrium by tuning the excitation laser intensity. By use of the long-term particle tracking technique, the time evolution of a large amount of active particles is resolvable. For low laser intensity, the suspension is driven to near equilibrium state with homogeneous superdiffusion motion...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346625/complete-genomic-and-transcriptional-landscape-analysis-using-third-generation-sequencing-a-case-study-of-saccharomyces-cerevisiae-cen-pk113-7d
#3
Piroon Jenjaroenpun, Thidathip Wongsurawat, Rui Pereira, Preecha Patumcharoenpol, David W Ussery, Jens Nielsen, Intawat Nookaew
Completion of eukaryal genomes can be difficult task with the highly repetitive sequences along the chromosomes and short read lengths of second-generation sequencing. Saccharomyces cerevisiae strain CEN.PK113-7D, widely used as a model organism and a cell factory, was selected for this study to demonstrate the superior capability of very long sequence reads for de novo genome assembly. We generated long reads using two common third-generation sequencing technologies (Oxford Nanopore Technology (ONT) and Pacific Biosciences (PacBio)) and used short reads obtained using Illumina sequencing for error correction...
January 13, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29346094/reweighted-low-rank-matrix-analysis-with-structural-smoothness-for-image-denoising
#4
Hengyou Wang, Yigang Cen, Zhiquan He, Zhihai He, Ruizhen Zhao, Fengzhen Zhang
In this paper, we develop a new low-rank matrix recovery algorithm for image denoising. We incorporate the total variation (TV) norm and the pixel range constraint into the existing reweighted low-rank matrix analysis to achieve structural smoothness and to significantly improve quality in the recovered image. Our proposed mathematical formulation of the low-rank matrix recovery problem combines the nuclear norm, TV norm, and norm, thereby allowing us to exploit the low-rank property of natural images, enhance the structural smoothness, and detect and remove large sparse noise...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29346077/three-dimensional-graphene-biointerface-with-extremely-high-sensitivity-to-single-cancer-cell-monitoring
#5
Xiahua Wang, Aiping Liu, Yun Xing, Hongwei Duan, Weizhong Xu, Qi Zhou, Huaping Wu, Cen Chen, Benyong Chen
We developed a three-dimensional biointerface of graphene-based electrical impedance sensor for metastatic cancer diagnosis at single-cell resolution. Compared with traditional impedance sensor with two-dimensional interface, the graphene biointerface mimiced the topography and somatotype features of cancer cells, achieving more comprehensive and thorough single cell signals in the three-dimensional space. At the nodes of physiological behavior change of single cell, namely cell capture, adhesion, migration and proliferation, the collected electrical signals from graphene biointerface were about two times stronger than those from the two-dimensional gold interface due to the substantial increase in contact area and significant improvement of topographical interaction between cells and graphene electrode...
January 9, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29334300/the-impact-of-early-molecular-response-in-children-and-adolescents-with-chronic-myeloid-leukemia-treated-with-imatinib-a-single-center-study-from-china
#6
Haigang Shao, Zhao Zeng, Jiannong Cen, Jun Zhang, Shuxiao Bai, Chunxiao Wu, Yanlei Gong, Yong Wang, Huiying Qiu, Suning Chen, Jinlan Pan
Chronic myeloid leukemia (CML) is rare among children and adolescents. The early molecular response (EMR) is an important prognostic significance for adult CML patients. This study explored the impact of EMR on the prognosis in 40 children and adolescents with CML-CP treated with imatinib (IM). Our results showed that a high proportion of patients failed to achieve the BCR-ABL1/ABL1 International Scale (IS) ≤ 10% at 3 months. Children with a BCR-ABL1/ABL1 ≤ 10% at 3 months and <1% at 6 months increased the rate of achieving complete cytogenetic response (CCyR) and/or major molecular response (MMR) at 12 months compared to those with BCR-ABL1/ABL1 > 10%...
January 15, 2018: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/29332810/sensitive-fluorescence-sensing-of-t4-polynucleotide-kinase-activity-and-inhibition-based-on-dna-polydopamine-nanospheres-platform
#7
Yao Cen, Wen-Jing Deng, Ru-Qin Yu, Xia Chu
5'-Polynucleotide kinase (PNK) is a crucial enzyme that catalyzes the phosphorylation of nucleic acid with 5'-OH termini and this phosphorylation reaction has been involved in many important cellular activities. The evaluation of PNK activity has received an increasing attention due to the significance of PNK. Here, the polydopamine nanospheres (PDANS) could adsorb single-stranded DNA (ssDNA) through π-π stacking or hydrogen bonding between nucleobases and aromatic groups of PDANS, while the interaction between double-stranded DNA (dsDNA) with PDANS was weakened due to the changed conformation...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29328531/thalamic-atrophy-in-ms-an-mri-marker-of-neurodegeneration-throughout-disease
#8
Christina J Azevedo, Steven Y Cen, Sankalpa Khadka, Shuang Liu, John Kornak, Yonggang Shi, Ling Zheng, Stephen L Hauser, Daniel Pelletier
OBJECTIVE: Thalamic volume is a candidate MRI-based marker associated with neurodegeneration to hasten development of neuroprotective treatments. Our objective is to describe the longitudinal evolution of thalamic atrophy in MS and normal aging, and to estimate sample sizes for study design. METHODS: 601 subjects (2632 MRI scans) were analyzed. 520 subjects with relapse-onset MS [CIS(90); RR(392); SP(38)] underwent annual standardized 3T MRI scans for an average of 4...
January 12, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29325993/serum-haptoglobin-in-chinese-patients-with-alzheimer-s-disease-and-mild-cognitive-impairment-a-case-control-study
#9
Cen-Jing Zhu, Guo-Xin Jiang, Jin-Mei Chen, Zhi-Ming Zhou, Qi Cheng
BACKGROUND: Serum level of Haptoglobin (Hp) maybe associated with Alzheimer's disease (AD) and mild cognitive impairment (MCI). OBJECTIVE: To investigate associations between serum Hp and AD, as well as between Hp and MCI. METHODS: Serum levels of Hp were measured and analyzed for 51 patients with AD, 139 patients with MCI and their healthy controls matched with sex and age. All study subjects were from a survey among residents aged 60 years and over in a community located in the southwest suburb of Shanghai...
January 8, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29325381/-longterm-surgery-outcome-of-m%C3%A3-bius-syndrome
#10
J Cen, X L Kang, J Yu, L Y Dong, Y Wei, K X Zhao
Objective: To investigate clinical features and the long-term surgery results of Möbius syndrome patients. Methods: This investigation presents a retrospective study of Möbius syndrome in 7 children we found since 2009. All 7 patients had MRI scan, ocular alignment in primary position, the limitation of versions and ductions and forced duction under general anesthesia. Early surgery is done to the 7 esotropia children. The pre-operative and post-operative outcomes, including the ocular alignment, deviation measurements and ocular rotations, were evaluated and compared...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29321958/diagnostic-value-of-strand-specific-mirna-101-3p-and-mirna-101-5p-for-hepatocellular-carcinoma-and-a-bioinformatic-analysis-of-their-possible-mechanism-of-action
#11
Xia Yang, Yu-Yan Pang, Rong-Quan He, Peng Lin, Jie-Mei Cen, Hong Yang, Jie Ma, Gang Chen
There is accumulating evidence that miRNA might serve as potential diagnostic and prognostic markers for various types of cancer. Hepatocellular carcinoma (HCC) is the most common type of malignant lesion but the significance of miRNAs in HCC remains largely unknown. The present study aimed to establish the diagnostic value of miR-101-3p/5p in HCC and then further investigate the prospective molecular mechanism via a bioinformatic analysis. First, the miR-101 expression profiles and parallel clinical parameters from 362 HCC patients and 50 adjacent non-HCC tissue samples were downloaded from The Cancer Genome Atlas (TCGA)...
January 2018: FEBS Open Bio
https://www.readbyqxmd.com/read/29321799/independent-and-combined-effects-of-environmental-factors-and-mir-126-mir-143-and-mir-145-on-the-risk-of-coronary-heart-disease
#12
Da-Cen Lin, Jia-Bing Lin, Zhou Chen, Rong Chen, Chun-Yu Wan, Shao-Wei Lin, Qi-Shuang Ruan, Huang-Yuan Li, Si-Ying Wu
Objective: To evaluate the effects of environmental factors and microRNAs (miRNAs) (miR-126, miR-143, and miR-145) on the risk of coronary heart disease (CHD). Methods: A frequency-matched case-control study (450 patients, 450 controls) was conducted from April 2014 to December 2016 in Fuzhou City, China. Environmental factors were investigated using a self-administered questionnaire, and the expression levels of miR-126, miR-143, and miR-145 were determined by quantitative real-time Polymerase Chain Reaction (PCR) in peripheral blood mononuclear cells...
November 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29316854/highly-stretchable-ha-sa-hydrogels-for-tissue-engineering
#13
Chengcheng Zhu, Rui Yang, Xiaobin Hua, Hong Chen, Jumei Xu, Rile Wu, Lian Cen
A highly stretchable hyaluronic acid (HA)/sodium alginate (SA) hydrogel was developed in this study based on an interpenetrating polymer network. HA/SA hydrogels were prepared by mixing two polysaccharides followed by covalent crosslinking via epoxy groups on HA molecules and ionic crosslinking via divalent ions on SA chains sequentially. The effect of HA/SA ratio on the pore size and distribution, swelling ratio, elongation and rheological properties as well as protein loading and release properties of HA/SA hydrogels was explored...
January 10, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29314496/a-highly-stable-cu-based-catalyst-for-clarifying-the-catalytic-roles-of-cu0-and-cu-species-in-methanol-dehydrogenation
#14
Huanhuan Yang, Yanyan Chen, Xiaojing Cui, Guofu Wang, Youliang Cen, Tiansheng Deng, Wenjun Yan, Jie Gao, Shanhui Zhu, Unni Olsbye, Jianguo Wang, Weibin Fan
Identification of active copper species, and further illustration of catalytic mechanism of Cu-based catalysts is still a challenge because of the mobility and evolution of Cu0 and Cu+ species in the reaction process. Thus, an unprecedentedly stable Cu-based catalyst was fabricated by uniformly embedding Cu nanoparticles in mesoporous silica shell for clarifying the catalytic roles of Cu0 and Cu+ with dehydrogenation of methanol to methyl formate by combining isotope-labeling experiment, in situ spectroscopy and DFT calculations...
January 4, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29312744/pathway-and-application-value-of-exploration-of-the-pulmonary-artery-by-endobronchial-ultrasound
#15
Peng Li, Cen Wu, Wei Zheng, Li Zhao
Background: The current standard methods for detecting pulmonary artery diseases are pulmonary artery enhanced computed tomography (CT) scan and pulmonary arteriography. However, some patients cannot tolerate these procedures for various reasons. The present study aimed to investigate the feasibility and operation process of endobronchial ultrasound (EBUS) in exploring the pulmonary artery. Methods: Based on normal contrast-enhanced chest CT images, the sites and process for exploring the pulmonary arteries were established...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312640/comparing-the-orbit-and-has-bled-bleeding-risk-scores-in-anticoagulated-atrial-fibrillation-patients-a-systematic-review-and-meta-analysis
#16
Cen Wang, Ye Yu, Wengen Zhu, Jianhua Yu, Gregory Y H Lip, Kui Hong
Background: The HAS-BLED and ORBIT scores have been proposed to assess bleeding risk in anticoagulated atrial fibrillation patients. We performed a systematic review and meta-analysis to compare the predictive ability by using these two scores. Materials and Methods: We searched the Cochrane Library, Elsevier and PubMed databases for related studies. Statistical analysis was performed with Revman 5.3 Manager software. We chose the C-statistic to reflect the diagnostic value...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29310397/massive-rare-desmoplastic-fibroma-of-the-ilium-and-ischium-in-a-young-adult-a-case-report
#17
Xin-Nan Ma, Shuai Qiang, Tian-Yi Liu, Mei-Yu Cao, Song-Cen Lv
RATIONALE: Desmoplastic fibroma (DF) is a rare, locally invasive but benign bone tumor. It represents one of the rarest bone diseases, with an incidence of only 0.11% of all primary bone tumors. PATIENT CONCERNS: Herein, a case of massive and unusual DF, with simultaneous involvement of ilium and ischium, is described. A 29-year-old man suffered minor pain in his right hip for 2 years. It worsened after sudden movements, which prevented him from walking normally...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305732/anatomy-of-the-retro-oesophageal-major-aortopulmonary-collateral-arteries-in-patients-with-pulmonary-atresia-with-ventricular-septal-defect-results-from-preoperative-cta
#18
Qianjun Jia, Jianzheng Cen, Jinglei Li, Jian Zhuang, Hui Liu, Qun Zhang, Xiaoqing Liu, Meiping Huang, Changhong Liang
OBJECTIVES: To assess the frequency and anatomy of retro-oesophageal aortopulmonary collateral arteries (REMs) in patients with pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA-VSD-MAPCAs). METHODS: A total of 130 consecutive PA-VSD-MAPCA patients with preoperative CT angiography (CTA) data who underwent cardiac surgery were included. A detailed analysis of MAPCA anatomy was performed using CTA. RESULTS: A REM was identified in 82/130 included patients (63 %)...
January 5, 2018: European Radiology
https://www.readbyqxmd.com/read/29305199/quantitative-contour-analysis-as-an-image-based-discriminator-between-benign-and-malignant-renal-tumors
#19
Felix Y Yap, Darryl H Hwang, Steven Y Cen, Bino A Varghese, Bhushan Desai, Brian D Quinn, Megha Nayyar Gupta, Nieroshan Rajarubendra, Mihir M Desai, Manju Aron, Gangning Liang, Monish Aron, Inderbir S Gill, Vinay A Duddalwar
OBJECTIVES: To investigate whether morphologic analysis can differentiate benign versus malignant renal tumors on clinically acquired imaging. METHODS: Between 2009 and 2014, 3D tumor volumes were manually segmented from contrast-enhanced computerized tomography (CT) images from 150 patients with predominantly solid, non-macroscopic fat-containing renal tumors: 100 renal cell carcinomas (RCC) and 50 benign lesions (e.g. oncocytoma, lipid-poor angiomyolipoma). Tessellated 3D tumor models were created from segmented voxels using MATLAB code...
January 2, 2018: Urology
https://www.readbyqxmd.com/read/29290538/appropriate-excision-time-of-heterotopic-ossification-in-elbow-caused-by-trauma
#20
Shu-Kun He, Min Yi, Gang Zhong, Shi-Qiang Cen, Jia-Lei Chen, Fu-Guo Huang
OBJECTIVE: The aim of this study was to investigate the optimal timing for the resection of heterotopic ossification (HO) of the elbow. METHODS: We retrospectively reviewed 42 patients who were treated operatively for heterotopic ossification of the elbow from March 2010 to December 2014 at our institution. The patients were divided into early (before 12 months) and late (after 12 months) excision groups. In the early excision group (17 patients), the average time from the initial injury to HO excision was 7...
December 28, 2017: Acta Orthopaedica et Traumatologica Turcica
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