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https://www.readbyqxmd.com/read/27933977/enhanced-ultraviolet-random-lasing-from-au-mgo-zno-heterostructure-by-introducing-p-cu2o-hole-injection-layer
#1
Cen Zhang, Juan Zhang, Weizhen Liu, Haiyang Xu, Shuai Hou, Chunliang Wang, Liu Yang, Zhongqiang Wang, Xinhua Wang, Yichun Liu
Ultraviolet light-emitting devices (LEDs) were fabricated on the basis of Au/MgO/ZnO metal/insulator/semiconductor (MIS) heterostructures. By introducing a thermally oxidized p-type Cu2O hole-injection layer into this MIS structure, enhanced ultraviolet electroluminescence (EL) and random lasing with reduced threshold injection current are achieved. The enhancement mechanism is attributed to effective hole transfer from p-Cu2O to i-MgO under forward bias, which increases the initial carrier concentration of MgO dielectric layer and further promotes "impact-ionization" effect induced carrier generation and injection...
November 23, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27933873/amelioration-of-experimental-autoimmune-encephalomyelitis-by-isogarcinol-extracted-from-garcinia-mangostana-l-mangosteen
#2
Mengqi Wang, Yufei Xie, Youxiu Zhong, Juren Cen, Lei Wang, Yuanyuan Liu, Ying Zhu, Li Tong, Qun Wei
Isogarcinol is a new natural immunosuppressant that was extracted from Garcinia mangostana L. in our laboratory. Knowledge of its effects on treatable diseases and its mechanism of action is still very limited. In this study, we explored the therapeutic effect of isogarcinol in experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). Treatment with oral 100 mg/kg isogarcinol markedly ameliorated clinical scores, alleviated inflammation and demyelination of the spinal cord, and reduced intracranial lesions in EAE mice...
November 30, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27927839/does-medicare-advantage-reduce-racial-disparity-in-30-day-rehospitalization-for-medicare-beneficiaries
#3
Yue Li, Xi Cen, Xueya Cai, Dongliang Wang, Caroline Pinto Thirukumaran, Laurent G Glance
This study determined potential racial and ethnic disparities in risk for all-cause 30-day readmission among traditional Medicare (TM) and Medicare Advantage (MA) beneficiaries initially hospitalized for acute myocardial infarction, congestive heart failure, or pneumonia. Our analyses of New York State hospital administrative data between 2009 and 2012 found that overall 30-day readmission rate declined from 22.0% in 2009 to 20.7% in 2012 for TM beneficiaries, and from 20.2% in 2009 to 17.9% in 2012 for MA beneficiaries...
December 6, 2016: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/27923643/anthraquinone-derivative-exerted-hormetic-effect-on-the-apoptosis-in-oxygen-glucose-deprivation-induced-pc12-cells-via-erk-and-akt-activated-nrf2-ho-1-signaling-pathway
#4
Lu Liu, Weiwei Huang, Jianhong Wang, Huiling Song, Juan Cen, Biansheng Ji
There were accumulated evidences that agents may attenuate neurological disorders through a hormetic effect. This study was designed to investigate hormetic effect of BME on the oxygen-glucose deprivation (OGD)-induced mitochondrial apoptosis in NGF-differentiated PC12 cells. The effect of BME on the intracellular reactive oxygen species (iROS) formation and pro-survival signals mediated by ERK and Akt as well as transcription factor nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) pathways was also determined...
December 3, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27923502/comparison-of-gas-chromatography-mass-spectrometry-and-gas-chromatography-tandem-mass-spectrometry-with-electron-ionization-for-determination-of-n-nitrosamines-in-environmental-water
#5
Wenwen Chen, Xiaoshui Li, Huanfang Huang, Xuetao Zhu, Xiaoyu Jiang, Yuan Zhang, Kuang Cen, Lunshan Zhao, Xiuli Liu, Shihua Qi
N-nitrosamines are trace organic contaminants of environmental concern when present in groundwater and river water due to their potent carcinogenicity. Therefore, N-nitrosamine analysis is increasingly in demand. Gas chromatography-mass spectrometry (GC-MS) and GC-tandem mass spectrometry (GC-MS/MS), both with electron ionization (EI), were compared for analysis of nine N-nitrosamines extracted from environmental water matrices. A total of 20 fishpond water, river water, and groundwater samples from Sihui and Shunde, China were collected for a survey of N-nitrosamine concentrations in real water samples...
December 3, 2016: Chemosphere
https://www.readbyqxmd.com/read/27923438/the-combined-effects-of-teacher-child-and-peer-relationships-on-children-s-social-emotional-adjustment
#6
Cen Wang, Maria Hatzigianni, Ameneh Shahaeian, Elizabeth Murray, Linda J Harrison
Teachers and peers represent two important dimensions of the classroom social ecology that have important implications for children's social-emotional adjustment. This study examined the combined effects of teacher-child relationships (TCR) and peer relationships for 6-7year-old children on their social-emotional adjustment at 8-9years. The sample was comprised of children and their teachers participating in the Longitudinal Study of Australian Children (n=2857). Teachers reported on TCR, peer relationships, and children's emotional well-being, and children provided self-reported self-concept and school liking during a face-to-face interview...
December 2016: Journal of School Psychology
https://www.readbyqxmd.com/read/27921117/mcp1-triggers-monocyte-dysfunctions-during-abnormal-osteogenic-differentiation-of-mesenchymal-stem-cells-in-ankylosing-spondylitis
#7
Zhongyu Xie, Peng Wang, Jinteng Li, Yuxi Li, Shan Wang, Xiaohua Wu, Suhe Sun, Shuizhong Cen, Hongjun Su, Wen Deng, Zhenhua Liu, Yi Ouyang, Yanfeng Wu, Huiyong Shen
: Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by pathological osteogenesis and inflammation. However, the pathogenesis of AS and the pathological relationship between osteogenesis and inflammation in this disease remain largely unknown. Mesenchymal stem cells (MSCs) are multipotent progenitor cells capable of osteogenic differentiation and immunoregulation. Recently, we demonstrated that MSCs from AS patients (ASMSCs) have a greater potential for osteogenic differentiation than MSCs from healthy donors (HDMSCs), which therefore seems to be a component of pathological osteogenesis in AS...
December 5, 2016: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/27920928/-trans-chlorido-2-rp-2-methyl-sulfan-yl-ferro-cen-yl-2-5-6-7-tetra-hydro-pyrrolo-1-2-c-imidazol-3-yl-idene-bis-tri-phenyl-phosphane-%C3%AE%C2%BAp-palladium-ii-hexa-fluorido-phosphate-di-chloro-form-disolvate
#8
Cody Wilson-Konderka, Alan J Lough, Costa Metallinos
The title solvated complex, [FePd(C5H5)(C12H13N2S)Cl(C18H15P)2]PF6·2CHCl3, bearing a chiral ferrocenyl pyrrolo-imidazolyl-idene N-heterocyclic carbene (NHC) ligand, was synthesized by oxidative addition of a chloro-imidazolium salt to Pd(PPh3)4. The Pd(II) ion is coordinated in a slightly distorted square-planar coordination geometry, with the Cl atom trans to the coordinating C atom of the pyrrolo-imidazolyl-idene ligand. The complex features a pendant thio-ether group that is not involved in coordination to Pd...
September 1, 2016: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/27909311/insights-into-the-phosphoryl-transfer-mechanism-of-human-ubiquitous-mitochondrial-creatine-kinase
#9
Quanjie Li, Shuai Fan, Xiaoyu Li, Yuanyuan Jin, Weiqing He, Jinming Zhou, Shan Cen, ZhaoYong Yang
Human ubiquitous mitochondrial creatine kinase (uMtCK) is responsible for the regulation of cellular energy metabolism. To investigate the phosphoryl-transfer mechanism catalyzed by human uMtCK, in this work, molecular dynamic simulations of uMtCK∙ATP-Mg(2+)∙creatine complex and quantum mechanism calculations were performed to make clear the puzzle. The theoretical studies hereof revealed that human uMtCK utilizes a two-step dissociative mechanism, in which the E227 residue of uMtCK acts as the catalytic base to accept the creatine guanidinium proton...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27907882/thorium-229-quantified-in-historical-thorium-228-capsules
#10
Sven Boden, Koen Vints, Simone Cagno, Dominic Maertens, Karen Van Hecke, Thomas Cardinaels
Thorium-229 is a valuable, but scarce, radionuclide for nuclear clock applications or targeted alpha therapy. While it is mostly produced by the decay of (233)U, (229)Th can also be produced by neutron irradiation of (226)Ra. At SCK•CEN, capsules containing mainly (228)Th (by-product of (226)Ra irradiation) were characterized to quantify the present amounts of (229)Th, (228)Th, (227)Ac, (226)Ra with high resolution gamma spectroscopy, after a decay period of 40 years in which (228)Th has decayed. High purity (229)Th was quantified, and after recovery using radiochemical separation processes, it can be used to support ongoing research...
November 24, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/27903117/risk-factors-associated-with-the-surgical-management-of-craniopharyngiomas-in-pediatric-patients-analysis-of-1961-patients-from-a-national-registry-database
#11
Joshua Bakhsheshian, Diana L Jin, Ki-Eun Chang, Ben A Strickland, Dan A Donoho, Steven Cen, William J Mack, Frank Attenello, Eisha A Christian, Gabriel Zada
OBJECTIVE Patient demographic characteristics, hospital volume, and admission status have been shown to impact surgical outcomes of sellar region tumors in adults; however, the data available following the resection of craniopharyngiomas in the pediatric population remain limited. The authors sought to identify potential risk factors associated with outcomes following surgical management of pediatric craniopharyngiomas. METHODS The Nationwide Inpatient Sample database and Kids' Inpatient Database were analyzed to include admissions for pediatric patients (≤ 18 years) who underwent a transcranial or transsphenoidal craniotomy for resection of a craniopharyngioma...
December 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27901073/thd-module-extractor-an-application-for-cen-module-extraction-and-interesting-gene-identification-for-alzheimer-s-disease
#12
Tulika Kakati, Hirak Kashyap, Dhruba K Bhattacharyya
There exist many tools and methods for construction of co-expression network from gene expression data and for extraction of densely connected gene modules. In this paper, a method is introduced to construct co-expression network and to extract co-expressed modules having high biological significance. The proposed method has been validated on several well known microarray datasets extracted from a diverse set of species, using statistical measures, such as p and q values. The modules obtained in these studies are found to be biologically significant based on Gene Ontology enrichment analysis, pathway analysis, and KEGG enrichment analysis...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27894386/-study-of-the-correlation-between-the-expression-of-angiotensin-%C3%A2-and-its-receptors-and-collagen-deposition-in-human-keloid
#13
J J Chen, X J Wu, Z Y Zhang, Z X Chen, Y Cen
Objective: To study the correlation between the expression of angiotensin Ⅱ, angiotensin Ⅱ type 1 receptor (AT1R), angiotensin Ⅱ type 2 receptor (AT2R) and collagen deposition in human keloid. Methods: The keloid from 19 keloid patients and normal skin from 13 patients performed with free skin transplantation hospitalized in our unit from May 2014 to January 2015 were obtained. The expressions of angiotensin Ⅱ, AT1R, and AT2R were detected by immunohistochemical staining, and the results were semi-quantitatively analyzed by immunohistochemical scoring...
November 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/27894383/-integrated-diagnosis-and-treatment-of-scar
#14
Y Cen, J J Chen
Scar is the common disease in the field of burn and plastic surgery, and its diagnosis and treatment should be involved in overwhelming majority hospitals. There are many substandard methods and medical hidden dangers in diagnosis and treatment of scar, due to the unevenness of doctors' clinical experience. According to the classification of integral scar and diabrotic scar, the problems related to diagnosis and treatment of scar are systemically summarized and normalized in this article for decrease in the incidence of adverse events and medical hidden dangers...
November 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/27889660/the-ph-dependent-leaching-behavior-of-slags-from-various-stages-of-a-copper-smelting-process-environmental-implications
#15
Alice Jarošíková, Vojtěch Ettler, Martin Mihaljevič, Bohdan Kříbek, Ben Mapani
The leaching behaviors of primary copper (Cu) slags originating from Ausmelt, reverbatory, and converter furnaces operating under a single technological process were compared to a residual slag tailing obtained by slag re-processing via flotation and metal recovery. The EN 12457-2 leaching test, used for assessment of the hazardous properties, was followed by the CEN/TS 14997 pH-static leaching test (pH range 3-12). Both leaching experiments were coupled with a mineralogical investigation of the primary and secondary phases as well as geochemical modeling...
November 24, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27889557/identification-of-a-hemolin-protein-from-actias-selene-mediates-immune-response-to-pathogens
#16
Cen Qian, Fang Wang, Baojian Zhu, Lei Wang, Guoqing Wei, Yu Sun, Sheng Li, Chaoliang Liu
Hemolins play an important role in development and innate immunity in insects. In this study, a hemolin cDNA of 1412bp in Actias selene (As-HEM) was isolated and its open reading frames (ORFs) were 420 amino acid residues. Sequence analysis indicated As-HEM was homologous to those hemolins from other insects species. The recombinant protein of As-HEM was expressed in Escherichia coli, and anti-As-HEM antibodies were prepared. Real-time quantitative PCR (RT-qPCR) and western blot results revealed that mRNA and protein levels of As-HEM were mostly detected in hemocytes and hemolymph...
November 24, 2016: International Immunopharmacology
https://www.readbyqxmd.com/read/27886312/standardisation-of-a-european-measurement-method-for-the-determination-of-anions-and-cations-in-pm2-5-results-of-field-trial-campaign-and-determination-of-measurement-uncertainty
#17
Sonya Beccaceci, Richard J C Brown, David M Butterfield, Peter M Harris, René P Otjes, Caroline van Hoek, Ulla Makkonen, Maria Catrambone, Rosalía Fernández Patier, Marc M G Houtzager, Jean-Philippe Putaud
European Committee for Standardisation (CEN) Technical Committee 264 'Air Quality' has recently produced a standard method for the measurements of anions and cations in PM2.5 within its Working Group 34 in response to the requirements of European Directive 2008/50/EC. It is expected that this method will be used in future by all Member States making measurements of the ionic content of PM2.5. This paper details the results of a field measurement campaign and the statistical analysis performed to validate this method, assess its uncertainty and define its working range to provide clarity and confidence in the underpinning science for future users of the method...
November 25, 2016: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/27883979/low-nt-probnp-levels-an-early-sign-for-the-diagnosis-of-ischemic-heart-failure
#18
Ya-Ru Zheng, Li-Fang Ye, Xue-Jiang Cen, Jing-Yang Lin, Jian-Wei Fu, Li-Hong Wang
BACKGROUND: N-terminal pro-brain natriuretic peptide (NT-proBNP) is seen to be mostly elevated in patients with acute heart failure (AHF). However, cases of AHF presenting with low NT-proBNP levels have been reported. In this study designed to investigate the factors associated with low NT-proBNP levels in AHF patients, we discovered that etiology and related factors have an influence on NT-proBNP levels. METHODS: In this study, 154 AHF patients met the study criteria (117 men, median age 74years; left ventricular ejection fraction [LVEF] 46±13%; New York Heart Association [NYHA] classes II-IV)...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27880010/abnormal-baseline-brain-activity-in-parkinson-s-disease-with-and-without-rem-sleep-behavior-disorder-a-resting-state-functional-mri-study
#19
Dan Li, Peiyu Huang, Yufeng Zang, Yuting Lou, Zhidong Cen, Quanquan Gu, Min Xuan, Fei Xie, Zhiyuan Ouyang, Bo Wang, Minming Zhang, Wei Luo
PURPOSE: To investigate the differences in spontaneous brain activity between Parkinson's disease (PD) patients with rapid eye movement sleep behavior disorder (RBD), PD patients without RBD, and normal controls, which may shed new light on the neural mechanism of RBD. MATERIALS AND METHODS: Eighteen PD patients with RBD, 16 patients without RBD, and 19 age- and gender-matched normal controls underwent clinical assessment and functional magnetic resonance imaging (fMRI) with a 3...
November 23, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27875749/systematic-investigation-on-the-turning-point-of-over-inflammation-to-immunosuppression-in-clp-mice-model-and-their-characteristics
#20
Dongmei Deng, Xiaoli Li, Chao Liu, Zhaoxia Zhai, Bin Li, Mei Kuang, Pan Li, Shenglan Shang, Yi Song, Yanyan Cen, Rongxin Qin, Yonglin Lu, Yibo Zhao, Hao Cheng, Jiang Zheng, Hong Zhou
Immunosuppression is involved in refractory innate and adaptive immune responses and is considered to be the predominant driving force for mortality in sepsis. The cecal ligation and puncture (CLP) model is regarded as a golden standard model for sepsis study, but the turning point of over-inflammation to immunosuppression was reported differently. Herein, systematic investigation on the turning point of over-inflammation to immunosuppression in CLP mice model was carried out. The results showed only the mortality of mice challenged with of Pseudomonas aeruginosa on Day 1 not other days after the surgery was higher than that of other mice with Sham surgery, suggesting Day 1 after the CLP surgery might be the turning point...
November 19, 2016: International Immunopharmacology
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