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Neck circumference AND insulin resistance

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https://www.readbyqxmd.com/read/29900162/association-of-insulin-resistance-with-lower-bone-volume-and-strength-index-of-the-proximal-femur-in-nondiabetic-postmenopausal-women
#1
Jaewon Yang, Namki Hong, Jee-Seon Shim, Yumie Rhee, Hyeon Chang Kim
Background: Type 2 diabetes mellitus is associated with an increased risk of osteoporotic fracture despite relatively preserved bone mineral density (BMD). Although this paradox might be attributed to the influence of insulin resistance (IR) on bone structure and material properties, the association of IR with femur bone geometry and strength indices remains unclear. Methods: Using data from the Cardiovascular and Metabolic Disease Etiology Research Center cohort study, we conducted a cross-sectional analysis among nondiabetic postmenopausal women...
May 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29791653/waist-circumference-is-an-effect-modifier-of-the-association-between-bone-mineral-density-and-glucose-metabolism
#2
Lygia N Barroso, Dayana R Farias, Marcia Soares-Mota, Heloisa Bettiol, Marco Antônio Barbieri, Milton Cesar Foss, Antônio Augusto M da Silva, Gilberto Kac
OBJECTIVE: The role of bone markers on insulin resistance (IR) remains controversial. The objective of this study is to evaluate the association between bone mineral density (BMD) and glucose metabolism and investigate if visceral hyperadiposity, evaluated by waist circumference (WC), is an effect modifier of this association. SUBJECTS AND METHODS: Cross-sectional analysis with 468 young adults from the fourth follow-up of the 1978/79 Ribeirão Preto prospective birth cohort, Brazil...
May 17, 2018: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29706998/melatonin-treatment-improves-insulin-resistance-and-pigmentation-in-obese-patients-with-acanthosis-nigricans
#3
Hang Sun, Xingchun Wang, Jiaqi Chen, Aaron M Gusdon, Kexiu Song, Liang Li, Shen Qu
Objective: This study aimed to determine the effects of melatonin on insulin resistance in obese patients with acanthosis nigricans (AN). Methods: A total of 17 obese patients with acanthosis nigricans were recruited in a 12-week pilot open trial. Insulin sensitivity, glucose metabolism, inflammatory factors, and other biochemical parameters before and after the administration of melatonin were measured. Results: After 12 weeks of treatment with melatonin (3 mg/day), homeostasis model assessment insulin resistance index (HOMA-IR) (8...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29561943/neck-circumference-in-adolescents-and-cardiometabolic-risk-a-sistematic-review
#4
REVIEW
Aisha Aguiar Morais, Urjel Aguiar Bouissou Morais, Maria Marta Sarquis Soares, Márcia Christina Caetano Romano, Joel Alves Lamounier
OBJECTIVE: To critically analyze articles on the relation between neck circumference (NC) in adolescents and: body mass index, fat distribution, metabolic syndrome and its individual components, and cardiovascular risk. METHOD: Systematic review undertaken by two independent researchers using the Pubmed/Medline, Lilacs/Medline, Scielo and Cochrane databases in English, Spanish and Portuguese in the period comprising the past 5 years. RESULTS: Eighteen (18) articles were selected...
January 2018: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29468088/neck-circumference-is-independently-associated-with-relative-systemic-hypertension-in-young-adults-with-sickle-cell-anaemia
#5
Lawrence A Olatunji, Olatunde P Olabode, Olawale M Akinlade, Abiola S Babatunde, Victoria A Olatunji, Ayodele O Soladoye
Background: A seemingly interesting observation in patients with sickle cell anaemia (SCA) is that they usually have lower systemic blood pressures (BP) and insulin resistance than persons in the general population in spite of chronic inflammation and vasculopathy. However, relative systemic hypertension (rHTN) has been linked to pulmonary hypertension, increased blood viscosity and renal insufficiency, which could indicate a risk of developing cardiometabolic disorder (CMD) in SCA.We therefore hypothesized that neck circumference (NC) and CMD marker; triglyceride glucose (TyG) index would independently predict rHTN in young adults with SCA in steady state...
2018: Clinical Hypertension
https://www.readbyqxmd.com/read/29412381/obese-with-higher-fndc5-irisin-levels-have-a-better-metabolic-profile-lower-lipopolysaccharide-levels-and-type-2-diabetes-risk
#6
Ivan Luiz Padilha Bonfante, Mara Patricia Traina Chacon-Mikahil, Diego Trevisan Brunelli, Arthur Fernandes Gáspari, Renata Garbellini Duft, Alexandre Gabarra Oliveira, Tiago Gomes Araujo, Mario Jose Abdalla Saad, Cláudia Regina Cavaglieri
OBJECTIVE: Thus, the aim of this study was to compare if higher or smaller fibronectin type 3 domain-containing protein 5 (FNDC5)/irisin levels are associated with inflammatory and metabolic markers, caloric/macronutrient intake, physical fitness and type 2 diabetes mellitus (T2DM) risk in obese middle-aged men, and also to correlate all variables analyzed with FNDC5/irisin. SUBJECTS AND METHODS: On the basis of a cluster study, middle-aged obese men (IMC: 31.01 ± 1...
December 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29157580/obstructive-sleep-apnea-and-diet-controlled-gestational-diabetes
#7
Ekasitt Wanitcharoenkul, Naricha Chirakalwasan, Somvang Amnakkittikul, Suranut Charoensri, Sunee Saetung, Suwannee Chanprasertyothin, La-Or Chailurkit, Panyu Panburana, Sommart Bumrungphuet, Boonsong Ongphiphadhanakul, Sirimon Reutrakul
BACKGROUND: Obstructive sleep apnea (OSA) was shown to be associated with gestational diabetes mellitus (GDM). However, prevalence of OSA in GDM women, its relationship to metabolic control, and predictive factors have not been studied. MATERIAL AND METHODS: Eighty-two obese pregnant women with diet-controlled GDM between 24 and 34 weeks of gestation participated. The Berlin questionnaire was used to assess OSA symptoms. OSA was diagnosed using an overnight monitor...
November 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29051986/the-relationship-between-fatty-liver-index-and-bone-mineral-density-in-koreans-knhanes-2010-2011
#8
S H Ahn, D H Seo, S H Kim, M-S Nam, S Hong
Analyses using a nationally representative cohort have revealed that high fatty liver index (FLI) is associated with low bone mineral density (BMD) regardless of insulin resistance in men, thereby supporting the deteriorated bone metabolism in nonalcoholic fatty liver disease (NAFLD). INTRODUCTION: NAFLD is linked to deteriorated bone health. We investigated the association of FLI, a scoring model for NAFLD, with BMD. METHODS: This was a population-based, cross-sectional study from the Korea National Health and Nutrition Examination Surveys including 4264 Koreans (1908 men and 2356 women)...
January 2018: Osteoporosis International
https://www.readbyqxmd.com/read/28884388/circulating-c3-and-glucose-metabolism-abnormalities-in-patients-with-osahs
#9
Xiaoxia Lu, Xiao Wang, Ting Xu, Yuan Feng, Yufeng Wang, Zechuan Cai, Bing Cao, Taoping Li
PURPOSE: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common breathing disorder during sleep characterized by multiple disease roots, including disorders of complement and glycometabolism. And the main purpose of the present study is to make clear the effect of complement C3 on glucose metabolism abnormalities in patients with OSAHS. METHODS: This was a cross-sectional study. Two hundred six patients, mean age 44.58 ± 11.84 years and 26 female patients (26/206), had been suspected with OSAHS and underwent overnight polysomnography...
May 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28832779/can-neck-circumference-predict-insulin-resistance-in-older-people-a-cross-sectional-study-at-primary-care-in-brazil
#10
Maria Auxiliadora Nogueira Saad, Maria Luiza Garcia Rosa, Giovanna Balarini Lima, Rubens Antunes da Cruz
This study focused on the correlation between neck circumference and other anthropometric measurements and cardiovascular risk factors and insulin resistance in the elderly in Niterói, Rio de Janeiro State, Brazil. This was a cross-sectional study in 411 patients seen in primary care. Anthropometric measurements including neck circumference, body mass index (BMI), waist circumference (WC), and waist-hip ratio (WHR) were recorded. Bioelectrical impedance analysis (BIA) estimated the percentage of total body fat (%TBF)...
August 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28728486/relationship-between-neck-circumference-insulin-resistance-and-arterial-stiffness-in-overweight-and-obese-subjects
#11
Francesco Fantin, Gabriele Comellato, Andrea P Rossi, Elisa Grison, Elena Zoico, Gloria Mazzali, Mauro Zamboni
Background Only a few studies have investigated the relationship between neck circumference and cardiometabolic risk. The aim of this study was to assess the relationships between neck circumference, waist circumference, metabolic variables and arterial stiffness in a group of overweight and obese subjects evaluating a possible independent role of neck circumference in determining arterial stiffness. Methods and results We studied 95 subjects (53 women) with an age range of 20-77 years and body mass index range from 25...
September 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28416405/development-validation-and-assessment-of-an-ischemic-stroke-or-transient-ischemic-attack-specific-prediction-tool-for-obstructive-sleep-apnea
#12
RANDOMIZED CONTROLLED TRIAL
Jason J Sico, H Klar Yaggi, Susan Ofner, John Concato, Charles Austin, Jared Ferguson, Li Qin, Lauren Tobias, Stanley Taylor, Carlos A Vaz Fragoso, Vincent McLain, Linda S Williams, Dawn M Bravata
BACKGROUND: Screening instruments for obstructive sleep apnea (OSA), as used routinely to guide clinicians regarding patient referral for polysomnography (PSG), rely heavily on symptomatology. We sought to develop and validate a cerebrovascular disease-specific OSA prediction model less reliant on symptomatology, and to compare its performance with commonly used screening instruments within a population with ischemic stroke or transient ischemic attack (TIA). METHODS: Using data on demographic factors, anthropometric measurements, medical history, stroke severity, sleep questionnaires, and PSG from 2 independently derived, multisite, randomized trials that enrolled patients with stroke or TIA, we developed and validated a model to predict the presence of OSA (i...
August 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28376939/investigation-of-vitamin-d-status-and-its-correlation-with-insulin-resistance-in-a-chinese-population
#13
Bing Han, Xiaojin Wang, Ningjian Wang, Qin Li, Yi Chen, Chunfang Zhu, Yingchao Chen, Fangzhen Xia, Xiaoqi Pu, Zhen Cang, Chaoxia Zhu, Meng Lu, Ying Meng, Hui Guo, Chi Chen, Weiping Tu, Bin Li, Ling Hu, Bingshun Wang, Yingli Lu
OBJECTIVE: Although many studies worldwide have focused on the relationship between vitamin D and insulin resistance, results remain controversial. Furthermore, concentrations of serum 25-hydroxyvitamin D (25(OH)D) in the Chinese population are unclear. We aimed to investigate vitamin D status and its correlation with insulin resistance among a Chinese adult population. DESIGN: Serum 25(OH)D, fasting blood glucose, fasting insulin, glycated Hb (HbA1c) and other metabolic parameters were assessed...
June 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/27990384/a-descriptive-study-of-facial-acanthosis-nigricans-and-its-association-with-body-mass-index-waist-circumference-and-insulin-resistance-using-homa2-ir
#14
Shyam Verma, Resham Vasani, Rajiv Joshi, Meghana Phiske, Pritesh Punjabi, Tushar Toprani
INTRODUCTION: The term facial acanthosis nigricans (FAN) lacks definition of precise clinical and histopathological features. We present a descriptive study of patients with FAN to define pigmentary patterns and estimate the prevalence of obesity and insulin resistance in these cases. MATERIALS AND METHODS: It is a prospective study that included all patients with classical AN of the neck and/or other areas with facial acanthosis nigricans described as brown-to-black macular pigmentation with blurred ill-defined margins, found on the zygomatic and malar areas...
November 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27930697/early-antenatal-prediction-of-gestational-diabetes-in-obese-women-development-of-prediction-tools-for-targeted-intervention
#15
RANDOMIZED CONTROLLED TRIAL
Sara L White, Debbie A Lawlor, Annette L Briley, Keith M Godfrey, Scott M Nelson, Eugene Oteng-Ntim, Stephen C Robson, Naveed Sattar, Paul T Seed, Matias C Vieira, Paul Welsh, Melissa Whitworth, Lucilla Poston, Dharmintra Pasupathy
All obese women are categorised as being of equally high risk of gestational diabetes (GDM) whereas the majority do not develop the disorder. Lifestyle and pharmacological interventions in unselected obese pregnant women have been unsuccessful in preventing GDM. Our aim was to develop a prediction tool for early identification of obese women at high risk of GDM to facilitate targeted interventions in those most likely to benefit. Clinical and anthropometric data and non-fasting blood samples were obtained at 15+0-18+6 weeks' gestation in 1303 obese pregnant women from UPBEAT, a randomised controlled trial of a behavioural intervention...
2016: PloS One
https://www.readbyqxmd.com/read/27766968/body-condition-score-morphometric-measurements-and-estimation-of-body-weight-in-mature-icelandic-horses-in-denmark
#16
Rasmus B Jensen, Signe H Danielsen, Anne-Helene Tauson
BACKGROUND: Obesity is related to the development of several diseases like insulin resistance and laminitis in horses. The prevalence of obesity among mature Icelandic horses in Denmark has not been investigated previously. This study aimed to find the prevalence of obesity, to compare body condition score (BCS) based on owner perception with that of an experienced person and to correlate the BCS to body weight (BW) and morphometric measures in a group of mature Icelandic horses in Denmark...
October 20, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27477619/insulin-sensitivity-body-composition-and-adipose-depots-following-12-w-combined-endurance-and-strength-training-in-dysglycemic-and-normoglycemic-sedentary-men
#17
COMPARATIVE STUDY
Torgrim Mikal Langleite, Jørgen Jensen, Frode Norheim, Hanne Løvdal Gulseth, Daniel Steensen Tangen, Kristoffer Jensen Kolnes, Ansgar Heck, Tryggve Storås, Guro Grøthe, Marius Adler Dahl, Anders Kielland, Torgeir Holen, Hans Jørgen Noreng, Hans Kristian Stadheim, Atle Bjørnerud, Egil Ivar Johansen, Birgitte Nellemann, Kåre Inge Birkeland, Christian A Drevon
CONTEXT: Insulin resistance and dysglycemia are associated with physical inactivity and adiposity, and may be improved by exercise. OBJECTIVE: Investigate the effect of exercise on insulin sensitivity, body composition and adipose depots in sedentary men with (n = 11) or without (n = 11) overweight and dysglycemia. MATERIAL AND METHODS: Euglycemic-hyperinsulinemic clamp, ankle-to-neck MRI, MRS, muscle and adipose tissue biopsies before and after 12 weeks combined strength and endurance exercise...
October 2016: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/27457430/relation-of-body-circumferences-to-cardiometabolic-disease-in-overweight-obese-subjects
#18
Ernesto Maddaloni, Ilaria Cavallari, Mariangela De Pascalis, Hillary Keenan, Kyoungmin Park, Silvia Manfrini, Raffaella Buzzetti, Giuseppe Patti, Germano Di Sciascio, Paolo Pozzilli
Body circumferences have been proposed as potential anthropometric measures for the assessment of cardiometabolic risk as they are independently associated with insulin resistance and diabetes. The aim of this study was to validate neck and wrist circumference and waist-to-hip ratio as practical markers of metabolic dysfunction and atherosclerosis; 120 subjects who underwent coronary angiography and carotid Doppler ultrasound were enrolled in this cross-sectional study. Exclusion criteria were history of diabetes, acute myocardial infarction, body mass index (BMI) <18...
September 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27324702/genetic-predisposition-to-obesity-is-associated-with-insulin-secretion-in-chinese-adults-the-cardiometabolic-risk-in-chinese-crc-study
#19
Jun Liang, Yuting Sun, Xuekui Liu, Yan Zhu, Ying Pei, Yu Wang, Qinqin Qiu, Manqing Yang, Lu Qi
AIMS: The etiological role of obesity in determining diabetes risk among Asians may be different from that among Caucasians. The current study aimed to investigate the association between genetic predisposition to obesity and measures of insulin secretion and resistance in a large Chinese cohort. METHODS: Study samples were from a community-based health examination survey in central China. A total of 2058 subjects with available biomarkers levels were included in the present study...
September 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27250602/-the-role-of-epicardial-fat-and-obesity-parameters-in-the-prediction-of-coronary-heart-disease
#20
Dana Prídavková, Daniela Kantárová, Renáta Lišková, Peter Červeň, František Kovář, Marián Mokáň
BACKGROUND: To assess the relationship of parameters of obesity in relationship to coronary angiography findings with correlation of epicardial fat (EF) thickness in uppermentioned context. METHODS: There were 80 patients examined (43 males, 37 postmenopausal females) undergoing elective coronary angiography. We examined the regular obesity parameters - BMI, waist circumference (WC), neck circumference (NC), total body fat (TBF), and visceral fat (VF) using bioimpedance...
April 2016: Vnitr̆ní Lékar̆ství
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