Klara Holikova, Iveta Selingerova, Petr Pospisil, Martin Bulik, Ludmila Hynkova, Ivana Kolouskova, Lucie Hnidakova, Petr Burkon, Marek Slavik, Jiri Sana, Tomas Holecek, Jiri Vanicek, Pavel Slampa, Radim Jancalek, Tomas Kazda
BACKGROUND: Changes in the hippocampus after brain metastases radiotherapy can significantly impact neurocognitive functions. Numerous studies document hippocampal atrophy correlating with the radiation dose. This study aims to elucidate volumetric changes in patients undergoing whole-brain radiotherapy (WBRT) or targeted stereotactic radiotherapy (SRT) and to explore volumetric changes in the individual subregions of the hippocampus. METHOD: Ten patients indicated to WBRT and 18 to SRT underwent brain magnetic resonance before radiotherapy and after 4 months...
2024: Neuro-oncology advances