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https://www.readbyqxmd.com/read/28323870/contribution-of-sortase-srta2-to-lactobacillus-casei-bl23-inhibition-of-staphylococcus-aureus-internalization-into-bovine-mammary-epithelial-cells
#1
Renata F S Souza, Julien Jardin, Chantal Cauty, Lucie Rault, Damien S Bouchard, Luis G Bermúdez-Humarán, Philippe Langella, Vicente Monedero, Núbia Seyffert, Vasco Azevedo, Yves Le Loir, Sergine Even
Probiotics have been considered as a promising strategy to prevent various diseases in both humans and animals. This approach has gained interest in recent years as a potential means to control bovine mastitis. In a previous study, we found that several L. casei strains, including BL23, were able to inhibit the internalization of S. aureus, a major etiologic agent of mastitis, into bovine mammary epithelial cells (bMEC). This antagonism required a direct contact between L. casei and bMEC or S. aureus, suggesting the inhibition relied on interactions between L...
2017: PloS One
https://www.readbyqxmd.com/read/28323028/early-behavioural-facilitation-by-temporal-expectations-in-complex-visual-motor-sequences
#2
Simone G Heideman, Freek van Ede, Anna C Nobre
In daily life, temporal expectations may derive from incidental learning of recurring patterns of intervals. We investigated the incidental acquisition and utilisation of combined temporal-ordinal (spatial/effector) structure in complex visual-motor sequences using a modified version of a serial reaction time (SRT) task. In this task, not only the series of targets/responses, but also the series of intervals between subsequent targets was repeated across multiple presentations of the same sequence. Each participant completed three sessions...
March 16, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28322759/validation-and-refinement-of-prediction-models-to-estimate-exercise-capacity-in-cancer-survivors-using-the-steep-ramp-test
#3
Martijn M Stuiver, Caroline S Kampshoff, Saskia Persoon, Wim Groen, Willem van Mechelen, Mai Jm Chinapaw, Johannes Brug, Frans Nollet, Marie-José Kersten, Goof Schep, Laurien M Buffart
OBJECTIVE: To further test the validity and clinical usefulness of the Steep Ramp Test (SRT) for estimating exercise tolerance in cancer survivors, by external validation and extension of previously published prediction models for VO2peak and Wpeak. DESIGN: Cross-sectional study. SETTING: Multicenter. PARTICIPANTS: Cardiopulmonary exercise tests (CPET) and SRT data from cancer survivors (n=283) in two randomized exercise trials...
March 18, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28318935/vector-model-supported-optimization-in-volumetric-modulated-arc-stereotactic-radiotherapy-planning-for-brain-metastasis
#4
Eva Sau Fan Liu, Vincent Wing Cheung Wu, Benjamin Harris, Matthew Foote, Margot Lehman, Lawrence Wing Chi Chan
Long planning time in volumetric-modulated arc stereotactic radiotherapy (VMA-SRT) cases can limit its clinical efficiency and use. A vector model could retrieve previously successful radiotherapy cases that share various common anatomic features with the current case. The prsent study aimed to develop a vector model that could reduce planning time by applying the optimization parameters from those retrieved reference cases. Thirty-six VMA-SRT cases of brain metastasis (gender, male [n = 23], female [n = 13]; age range, 32 to 81 years old) were collected and used as a reference database...
March 17, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28317443/deterioration-of-the-anammox-process-at-decreasing-temperatures-and-long-srts
#5
Maaike Hoekstra, Florence A de Weerd, Robbert Kleerebezem, Mark C M van Loosdrecht
The implementation of autotrophic nitrogen removal in the mainstream of a municipal wastewater treatment plant is currently pursued. Among the crucial unknown factors are the kinetic properties of anaerobic ammonium oxidising (anammox) bacteria at low temperatures, as typically encountered for sewage in winter. In this study we investigated the adaptation of a fast growing anammox culture to a lower temperature. In a membrane bioreactor a highly enriched anammox community was obtained at 30, 25 and 20°C. The culture grew as free cells and small flocs (50 -150µm)...
March 19, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28315610/sensory-processing-in-huntington-s-disease
#6
Ana Mirallave, Merche Morales, Christopher Cabib, Esteban J Muñoz, Pilar Santacruz, Xavier Gasull, Josep Valls-Sole
OBJECTIVE: An intriguing electrophysiological feature of patients with Huntington's disease (HD) is the delayed latency and decreased amplitude of somatosensory long-latency evoked potentials (LLeps). We investigated whether such dysfunction was associated with delayed conscious perception of the sensory stimulus. METHODS: Sixteen HD patients and 16 control subjects faced a computer screen showing the Libet's clock (Libet et al., 1983). In Rest trials, subjects had to memorize the position of the clock handle at perception of either electrical or thermal stimuli (AW)...
February 14, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28315230/clinical-outcome-and-molecular-characterization-of-brain-metastases-from-esophageal-and-gastric-cancer-a-systematic-review
#7
REVIEW
Michele Ghidini, Fausto Petrelli, Jens Claus Hahne, Annamaria De Giorgi, Laura Toppo, Claudio Pizzo, Margherita Ratti, Sandro Barni, Rodolfo Passalacqua, Gianluca Tomasello
The aim of the study was to collect the available data on central nervous system (CNS) metastases from esophageal and gastric cancer. A PubMed, EMBASE, SCOPUS, Web of Science, LILACS, Ovid and Cochrane Library search was performed. Thirty-seven studies including 779 patients were considered. Among the data extracted, treatment of tumor and brain metastases (BMs), time to BMs development, number and subsite, extracerebral metastases rate, median overall survival (OS) and prognostic factors were included. For esophageal cancer, the median OS from diagnosis of BMs was 4...
April 2017: Medical Oncology
https://www.readbyqxmd.com/read/28302573/stair-walking-is-more-energizing-than-low-dose-caffeine-in-sleep-deprived-young-women
#8
Derek D Randolph, Patrick J O'Connor
INTRODUCTION: The acute energizing effect of exercise and caffeine has never been examined in a single study of adults with chronic sleep deprivation but evidence from a study of this type could help individuals choose between these two common alertness-enhancing options. AIM: The apriori primary aim of this experiment was to compare the influence of 10-min of low-to-moderate intensity stair walking to the consumption of capsules containing 50mg caffeine or flour (placebo) on feelings of energy in physically active, college female caffeine users with chronic insufficient sleep...
March 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28301348/discord-among-radiation-oncologists-and-urologists-in-the-postoperative-management-of-high-risk-prostate-cancer
#9
Amar U Kishan, Gillian Duchesne, Pin-Chieh Wang, Jean-Claude M Rwigema, Arun U Kishan, Christopher Saigal, Matthew Rettig, Michael L Steinberg, Christopher R King
OBJECTIVE: To query specialty-specific differences regarding postoperative radiotherapy (RT) for high-risk prostate cancer. MATERIALS AND METHODS: Electronic mail survey of radiation oncologists (ROs) and urologists. We sought to maximize absolute response number to capture contemporary practice ethos. The outcome of interest was association between response and specialty. Training level/expertise, practice setting, percentage of consultation caseload consisting of high-risk prostate cancer, and nationality were set as effect modifiers for multivariate logistic regression...
March 15, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28297354/quantitative-evaluation-of-patient-setup-uncertainty-of-stereotactic-radiotherapy-with-the-frameless-6d-exactrac-system-using-statistical-modeling
#10
Vance Keeling, Sabbir Hossain, Hosang Jin, Ozer Algan, Salahuddin Ahmad, Imad Ali
The purpose of this study is to evaluate patient setup accuracy and quantify individual and cumulative positioning uncertainties associated with different hardware and software components of the stereotactic radiotherapy (SRS/SRT) with the frameless 6D ExacTrac system. A statistical model is used to evaluate positioning uncertainties of the different components of SRS/SRT treatment with the Brainlab 6D ExacTrac system using the positioning shifts of 35 patients having cranial lesions. All these patients are immobilized with rigid head-and-neck masks, simulated with Brainlab localizer and planned with iPlan treatment planning system...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296331/treatment-accuracy-without-rotational-setup-corrections-in-intracranial-srt
#11
Eeva Boman, Mika Kapanen, Marko Laaksomaa, Hanna Mäenpää, Simo Hyödynmaa, Pirkko-Liisa Kellokumpu-Lehtinen
The aim of this study was to evaluate the impact of actual rotational setup errors on dose distributions in intracranial stereotactic radiotherapy (SRT) with different alternatives for treatment position selection. A total of 38 SRT fractions from 18 patients were retrospectively evaluated with rotational setup errors obtained from actual treatments. The planning computed tomography (CT) images were rotated according to online cone-beam CT (CBCT) images and the dose distribution was recalculated to the rotated CT images using three different patient positionings derived from: 1) an automatic 6D match neglecting rotation correction (Auto6D); 2) an automatic 3D match (Auto3D); and 3) a manual 3D match from actual treatment (Treat3D)...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28290709/selection-of-test-setup-parameters-to-target-specific-signal-to-noise-regions-in-speech-on-speech-intelligibility-testing
#12
Filip M Rønne, Søren Laugesen, Niels Søgaard Jensen
OBJECTIVE: To investigate the magnitude of the change in speech-reception threshold (SRT) provided by altering four different test-setup parameters. Furthermore, to determine whether these changes in SRT are of a sufficient magnitude, such that they can be used to design a test-setup in future experiments that target a predefined signal-to-noise ratio (SNR) region. This could be particularly important if the test contrast investigated is confounded with test SNR. DESIGN: The investigated test-setup parameters were: Spatial separation between target (0°) and maskers (±15°, ±30°, ±45°, or ±75°), number of maskers (two, four or six), scoring method (scoring percent-correct words or sentences) and masker gender (same or opposite to target)...
March 14, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28286478/cortical-alpha-oscillations-predict-speech-intelligibility
#13
Andrew Dimitrijevic, Michael L Smith, Darren S Kadis, David R Moore
Understanding speech in noise (SiN) is a complex task involving sensory encoding and cognitive resources including working memory and attention. Previous work has shown that brain oscillations, particularly alpha rhythms (8-12 Hz) play important roles in sensory processes involving working memory and attention. However, no previous study has examined brain oscillations during performance of a continuous speech perception test. The aim of this study was to measure cortical alpha during attentive listening in a commonly used SiN task (digits-in-noise, DiN) to better understand the neural processes associated with "top-down" cognitive processing in adverse listening environments...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28279158/performance-and-reproducibility-on-shuttle-run-test-between-obese-and-non-obese-children-a-cross-sectional-study
#14
Cristiane A Moran, Maria Stella Peccin, Maria Teresa Bombig, Silvana Alves Pereira, Simone Dal Corso
BACKGROUND: Due to the increasing prevalence of obesity among children, Shuttle Run Test (SRT) has been used as primary outcome for assessment of both physical performance and responses to different physical training programs. Thus, this study aimed to compare the performance on SRT between obese and non-obese children and the reproducibility of two SRTs carried out on different days. METHODS: A cross-sectional study in which 40 children, aged from 8 to 10, were recruited from a public school...
March 9, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28274537/reenlargement-of-radiation-necrosis-after-stereotactic-radiotherapy-for-brain-metastasis-from-lung-cancer-during-bevacizumab-treatment
#15
Koji Furuuchi, Akihiro Nishiyama, Hiroshige Yoshioka, Toshihide Yokoyama, Tadashi Ishida
We describe a 55-year-old man who received stereotactic radiotherapy (SRT) for the treatment of brain metastasis from lung adenocarcinoma. Fourteen months after SRT, right-sided hemiparesis developed, and magnetic resonance imaging revealed progression of perifocal edema and an enhanced lesion. Cerebral radiation necrosis was diagnosed, and treatment with bevacizumab was initiated. The lesion clearly responded to bevacizumab therapy, but reenlarged 8 months later and was surgically resected. Histopathological analysis of the resected specimen revealed large areas of necrosis; however, viable tumor cells were detected in the necrotic areas...
March 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28269707/effects-of-lower-limb-electrical-stimulation-on-trunk-stability-in-persons-with-sci-during-walking-a-case-series
#16
Kamyar Momeni, Stephen Canton, Arvind Ramanujam, Erica Garbarini, Gail F Forrest
The purpose of the present case series was to investigate whether three lower limb rehabilitation training approaches have any effects on trunk stability of persons with motor complete SCI during a 10-minute assisted walk. These trainings included electrical stimulation (ES), standing retraining (SRT), and a novel multi-modality approach that combined ES with SRT. We observed that multi-muscle ES directed at the lower limbs had a prominent, indirect effect on the upper and lower muscles of the trunk. More specifically, trunk muscle activations of the ES+SRT subject increased after training for the more distal muscles of the trunk...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269324/a-simulation-analysis-of-the-variability-of-the-roving-level-hearing-test
#17
Greg D Watkins, Brett A Swanson, Gregg J Suaning
In the study of auditory prostheses, the Speech Recognition Threshold (SRT) is the Signal to Noise Ratio (SNR) at which 50% of words are correctly identified. SRT is typically measured using an adaptive procedure wherein speech is presented at a fixed sound pressure level (SPL) and the noise level is varied according to the subject's responses. A roving level SRT test has been used by researchers with the goal of including the effectiveness of Automatic Gain Control (AGC) systems in SRT measurements. The roving method presents speech at three different SPLs with the level for each sentence chosen pseudo-randomly, while adaptively varying the SNR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268974/neuromotor-response-of-the-leg-muscles-following-a-supine-stand-retraining-with-without-neuromuscular-electrical-stimulation-training-intervention-for-individuals-with-sci-a-case-series
#18
Stephen Canton, Kamyar Momeni, Arvind Ramanujam, Erica Garbarini, Gail F Forrest
The goal of this paper is to study the effects of supine and stand retraining (SRT) interventions with and without multi muscle neuromuscular electrical stimulation (NMES) on the neuromuscular EMG responses of the leg muscles for individuals with motor complete SCI during walking on a body-weight support (BWS) treadmill. The main outcome variables were EMG amplitude, integrated EMG and co-contraction indices (co-excitation and co-activation) collected during a 10-minute walking treadmill trial. Data was analyzed for the first, fifth and tenth minute of walking...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265650/the-effect-of-object-centered-instructions-in-cartesian-and-polar-coordinates-on-saccade-vector
#19
Jay A Edelman, Alexa M Mieses, Kira Konnova, David Shiu
Express saccades (ES) are the most reflexive saccadic eye movements, with very short reaction times of 70-110 ms. It is likely that ES have the shortest saccade reaction times (SRTs) possible given the known physiological and anatomical delays present in sensory and motor systems. Nevertheless, it has been demonstrated that a vector displacement of ES to spatially extended stimuli can be influenced by spatial cognition. Edelman, Kristjansson, and Nakayama (2007) found that when two horizontally separated visual stimuli appear at a random location, the spatial vector, but not the reaction time, of human ES is strongly influenced by an instruction to make a saccade to one side (either left or right) of a visual stimulus array...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28263587/rapid-achievement-of-nitritation-using-aerobic-starvation
#20
Wenlong Liu, Qing Yang, Bin Ma, Jun Li, Linna Ma, Shuying Wang, Yongzhen Peng
Rapid start-up of partial nitrification is of great significance for subsequent denitrification and anammox process, however slow nitritation hinders the application of these processes. The current study presents a novel strategy for achieving the nitritation using aerobic starvation and controlling sludge retention time (SRT). Activated sludge with high level of complete nitrification was introduced into an aerated reactor without feeding to start the aerobic starvation. The results showed that nitritation was rapidly achieved, while the shorter SRT (15 days) guaranteed the stability of nitritation with an average nitrite accumulation ratio (NAR) of more than 95%...
March 6, 2017: Environmental Science & Technology
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