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https://www.readbyqxmd.com/read/28933977/use-of-virtual-reality-intervention-to-improve-reaction-time-in-children-with-cerebral-palsy-a-randomized-controlled-trial
#1
Morteza Pourazar, Fatemeh Mirakhori, Rasool Hemayattalab, Fazlolah Bagherzadeh
PURPOSE: The purpose of this study was to investigate the training effects of Virtual Reality (VR) intervention program on reaction time in children with cerebral palsy. METHODS: Thirty boys ranging from 7 to 12 years (mean = 11.20; SD = .76) were selected by available sampling method and randomly divided into the experimental and control groups. Simple Reaction Time (SRT) and Discriminative Reaction Time (DRT) were measured at baseline and 1 day after completion of VR intervention...
September 21, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28933412/genetic-substrate-reduction-therapy-a-promising-approach-for-lysosomal-storage-disorders
#2
REVIEW
Maria Francisca Coutinho, Juliana Inês Santos, Liliana Matos, Sandra Alves
Lysosomal storage diseases are a group of rare genetic disorders characterized by the accumulation of storage molecules in late endosomes/lysosomes. Most of them result from mutations in genes encoding for the catabolic enzymes that ensure intralysosomal digestion. Conventional therapeutic options include enzyme replacement therapy, an approach targeting the functional loss of the enzyme by injection of a recombinant one. Even though this is successful for some diseases, it is mostly effective for peripheral manifestations and has no impact on neuropathology...
November 9, 2016: Diseases (Basel)
https://www.readbyqxmd.com/read/28928645/auditory-motor-mapping-training-in-a-more-verbal-child-with-autism
#3
Karen V Chenausky, Andrea C Norton, Gottfried Schlaug
We tested the effect of Auditory-Motor Mapping Training (AMMT), a novel, intonation-based treatment for spoken language originally developed for minimally verbal (MV) children with autism, on a more-verbal child with autism. We compared this child's performance after 25 therapy sessions with that of: (1) a child matched on age, autism severity, and expressive language level who received 25 sessions of a non-intonation-based control treatment Speech Repetition Therapy (SRT); and (2) a matched pair of MV children (one of whom received AMMT; the other, SRT)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28925733/comparison-of-the-buschke-selective-reminding-test-and-the-california-verbal-learning-test-second-edition-in-a-heterogeneous-sample-of-people-with-traumatic-brain-injury
#4
Damian Leitner, Harry Miller, Maya Libben
This study examined score and classification differences between the Buschke Selective Reminding Test (SRT) and the California Verbal Learning Test - Second Edition (CVLT-II) in a TBI sample. Seventy-nine participants with traumatic brain injury (TBI) were included and were comprised of 49 mild TBI, 11 moderate TBI, and 14 severe TBI. The majority of participants with mild TBI were involved in litigation. Scores were compared between the CVLT-II and SRT on the total sample and after segregating TBI severity...
September 19, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28924967/postoperative-radiotherapy-for-prostate-cancer-the-sooner-the-better-and-potential-to-reduce-toxicity-even-further
#5
Paolo Borghetti, Luigi Spiazzi, Claudia Cozzaglio, Sara Pedretti, Bruno Caraffini, Luca Triggiani, Diana Greco, Lilia Bardoscia, Fernando Barbera, Michela Buglione, Stefano Maria Magrini
PURPOSE: To evaluate biochemical relapse-free survival (bRFS), overall survival (OS), late rectal and bladder toxicities in a retrospective single institution series, also applying an in-house software for biological dose calculation. METHODS: 258 patients submitted to radiotherapy after prostatectomy were considered. Differences between groups were calculated using the log-rank test and the relevant clinical and therapeutic variables were considered for multivariate analysis...
September 18, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28921756/temporal-alignment-of-anticipatory-motor-cortical-beta-lateralisation-in-hidden-visual-motor-sequences
#6
Simone G Heideman, Freek van Ede, Anna C Nobre
Performance improves when participants respond to events that are structured in repeating sequences, suggesting that learning can lead to proactive anticipatory preparation. Whereas most sequence-learning studies have emphasized spatial structure, most sequences also contain a prominent temporal structure. We used MEG to investigate spatial and temporal anticipatory neural dynamics in a modified serial reaction-time (SRT) task. Performance and brain activity were compared between blocks with learned spatial-temporal sequences and blocks with new sequences...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28915893/dosimetric-comparison-of-different-treatment-modalities-for-stereotactic-radiotherapy
#7
Shih-Ming Hsu, Yuan-Chun Lai, Chien-Chung Jeng, Chia-Ying Tseng
BACKGROUND: The modalities for performing stereotactic radiotherapy (SRT) on the brain include the cone-based linear accelerator (linac), the flattening filter-free (FFF) volumetric modulated arc therapy (VMAT) linac, and tomotherapy. In this study, the cone-based linac, FFF-VMAT linac, and tomotherapy modalities were evaluated by measuring the differences in doses delivered during brain SRT and experimentally assessing the accuracy of the output radiation doses through clinical measurements...
September 16, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28912701/spectral-entropy-can-predict-changes-of-working-memory-performance-reduced-by-short-time-training-in-the-delayed-match-to-sample-task
#8
Yin Tian, Huiling Zhang, Wei Xu, Haiyong Zhang, Li Yang, Shuxing Zheng, Yupan Shi
Spectral entropy, which was generated by applying the Shannon entropy concept to the power distribution of the Fourier-transformed electroencephalograph (EEG), was utilized to measure the uniformity of power spectral density underlying EEG when subjects performed the working memory tasks twice, i.e., before and after training. According to Signed Residual Time (SRT) scores based on response speed and accuracy trade-off, 20 subjects were divided into two groups, namely high-performance and low-performance groups, to undertake working memory (WM) tasks...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28910575/behaviour-of-biopolymeric-substances-in-the-activated-sludge-of-an-mbr-system-working-with-high-hydraulic-retention-time
#9
Eugenio Marín, Jorge I Pérez, Miguel A Gómez
This study was undertaken to analyse the activated sludge of a membrane bioreactor (MBR), the behaviour of extracellular polymeric substances (EPS) and soluble microbial products (SMP) as well as their biopolymers composition, in the activated sludge of a membrane bioreactor (MBR) and their influence on membrane fouling were analysed. For the experiment an experimental fullscale MBR working with real urban wastewater at high hydraulic retention time with a variable sludge-retention time (SRT) was used. The MBR system worked in denitrification/nitrification conformation at a constant flow rate (Q = 0...
September 14, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28910331/reproducibility-of-frequency-dependent-low-frequency-fluctuations-in-reaction-time-over-time-and-across-tasks
#10
Zan-Zan Liu, Hui-Jie Qu, Zhuo-Ling Tian, Meng-Jian Han, Yi Fan, Lie-Zhong Ge, Yu-Feng Zang, Hang Zhang
OBJECTIVE: Increased levels of reaction time variability (RTV) are characteristics of sustained attention deficits. The clinical significance of RTV has been widely recognized. However, the reliability of RTV measurements has not been widely studied. The present study aimed to assess the test-retest reliability of RTV conventional measurements, e.g., the standard deviation (SD), the coefficient of variation (CV), and a new measurement called the amplitude of low frequency fluctuation (ALFF) of RT...
2017: PloS One
https://www.readbyqxmd.com/read/28893524/-hippocampus-brainstem-and-brain-dose-volume-constraints-for-fractionated-3-d-radiotherapy-and-for-stereotactic-radiation-therapy-limits-and-perspectives
#11
M Gérard, R Jumeau, B Pichon, J Biau, E Blais, J Horion, G Noël
Cerebral radiation-induced toxicities after radiotherapy (RT) of brain tumors are frequent. The protection of organs at risk (OAR) is crucial, especially for brain tumors, to preserve cognition in cancer survivors. Dose constraints of cerebral OAR used in conventional RT, radiosurgery (SRS) and stereotactic radiotherapy (SRT) are debated. In fact, they are based on historical cohorts or calculated with old mathematical models. Values of α/β ratio of cerebral OAR are also controversial leading to misestimate the equivalent dose in 2Gy fractions or the biological equivalent dose, especially during hypofractionated RT...
September 8, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28889832/intra-individual-cognitive-variability-an-examination-of-anam4-tbi-mil-simple-reaction-time-data-from-service-members-with-and-without-mild-traumatic-brain-injury
#12
Wesley R Cole, Emma Gregory, Jacques P Arrieux, F Jay Haran
OBJECTIVES: The Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM4) is a computerized cognitive test often used in post-concussion assessments with U.S. service members (SMs). Existing evidence, however, remains mixed regarding ANAM4's ability to identify cognitive issues following mild traumatic brain injury (mTBI). Studies typically examine ANAM4 by comparing mean scores to baseline or normative scores. A more fine-grained approach involves examining inconsistency within an individual's performance...
September 11, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28882693/different-effects-of-running-wheel-exercise-and-skilled-reaching-training-on-corticofugal-tract-plasticity-in-hypertensive-rats-with-cortical-infarctions
#13
ChanJuan Zhang, Yan Zou, Kui Li, Chao Li, YingPing Jiang, Ju Sun, Ruifang Sun, HongMei Wen
The approaches that facilitate white matter plasticity may prompt functional recovery after a stroke. The effects of different exercise methods on motor recovery in stroke rats have been investigated. However, it is not clear whether their effects on axonal plasticity different. The aim of this study was to compare the effects of the forced running wheel exercise (RWE) and skilled reaching training (SRT) on axonal plasticity and motor recovery. Cortical infarctions were generated in stroke-prone renovascular hypertensive rats...
September 4, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28878452/the-effects-of-spinal-support-device-on-pain-and-extensibility-of-the-hamstrings-in-patients-with-non-specific-low-back-pain
#14
Eun Tae Jeon, Jin-Hwa Jung, Jong Hoon Moon, Kyoung-Sim Jung, Young Sik Won, Sung-Jin Kim, Suk-Chan Hahm, Hwi-Young Cho
[Purpose] The objective of this study was to investigate the effects of spinal support device (SSD) on pain and hamstring extensibility in patients with non-specific low back pain (NSLBP). [Subjects and Methods] 20 patients with NSLBP were recruited and randomly assigned to either the SSD group or the control group. In the SSD group, SSD was applied; in the control group, bed rest in supine position was performed. Both groups underwent treatment 20 min/day, 3 times a week, for a duration of 4 weeks. To assess the hamstring extensibility, sit and reach test (SRT) was performed...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28869841/effects-of-attention-on-the-speech-reception-threshold-and-pupil-response-of-people-with-impaired-and-normal-hearing
#15
Thomas Koelewijn, Niek J Versfeld, Sophia E Kramer
For people with hearing difficulties, following a conversation in a noisy environment requires substantial cognitive processing, which is often perceived as effortful. Recent studies with normal hearing (NH) listeners showed that the pupil dilation response, a measure of cognitive processing load, is affected by 'attention related' processes. How these processes affect the pupil dilation response for hearing impaired (HI) listeners remains unknown. Therefore, the current study investigated the effect of auditory attention on various pupil response parameters for 15 NH adults (median age 51 yrs...
August 30, 2017: Hearing Research
https://www.readbyqxmd.com/read/28864223/risk-factors-for-disease-progression-after-postprostatectomy-salvage-radiation-long-term-results-of-a-single-institution-experience
#16
Danielle Rodin, Michael Drumm, Rebecca Clayman, Daniela L Buscariollo, Sigolene Galland-Girodet, Alec Eidelman, Adam S Feldman, Douglas M Dahl, Francis J McGovern, Aria F Olumi, Andrzej Niemierko, William U Shipley, Anthony L Zietman, Jason A Efstathiou
BACKGROUND: Salvage radiotherapy (SRT) has been successfully used for recurrent prostate cancer after radical prostatectomy; however, the optimal timing of SRT remains controversial. Our objective was to identify the risk factors for disease progression after SRT, with a focus on the pre-SRT prostate-specific antigen (PSA) levels in the modern era of PSA testing. PATIENTS AND METHODS: We performed a retrospective review of 551 consecutive patients who had undergone postradical prostatectomy SRT for recurrent prostate cancer from 2000 to 2013...
August 3, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28863992/nutrient-removal-and-energy-recovery-from-high-rate-activated-sludge-processes-impact-of-sludge-age
#17
Huoqing Ge, Damien J Batstone, Morgan Mouiche, Shihu Hu, Jurg Keller
This study evaluated high-rate activated sludge treatment across a broad range of short solids retention times (SRT)s (0.5-3d) and found a strong SRT-outcome dependence for performance and subsequent anaerobic degradability of the sludge. Up to 50% total nitrogen, and 35% ammonia removal was also achieved at the longer SRTs, via partitioning rather than reaction. The aerobic SRT significantly affected the anaerobic degradability of the sludge produced (p<0.001), with degradability increasing from 66% to over 80% while reducing the SRT from 3d to 0...
August 21, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28861691/post-prostatectomy-radiotherapy-adversely-affects-urinary-continence-irrespective-of-radiotherapy-regime
#18
J N Nyarangi-Dix, J Steimer, T Bruckner, H Jakobi, S A Koerber, B Hadaschik, J Debus, M Hohenfellner
PURPOSE: To investigate the influence of different postoperative radiotherapy (RT) regimes on post-prostatectomy continence and QoL. METHODS: Men after prostatectomy (RP) and RT were assigned in adjuvant (ART), early salvage (ESRT) and salvage radiotherapy (SRT) groups depending on time of initiation, indication and pre-RT-PSA (≤/>0.5 ng/ml). Continence and QoL outcomes were evaluated by validated questionnaire. Statistical analysis included students t test, Chi square, Fisher's test, ROC- and McNemar-Bowker-Analyses...
August 31, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28855023/fate-and-toxicity-of-zinc-oxide-nanomaterial-in-municipal-wastewaters
#19
Josh Smeraldi, Rajagopalan Ganesh, Turaj Hosseini, Leila Khatib, Betty H Olson, Diego Rosso
  The production of zinc nanomaterial has increased significantly over the past several years and, as a result, nanoparticles have navigated their way into wastewater streams. The transportation and toxicity of zinc nanomaterial within the wastewater treatment processes is not well known. In this study, the zinc nanomaterial and its fate were characterized in an activated sludge treatment process. The tests performed included batch studies to evaluate abiotic and biotic removal, toxicity studies to evaluate inhibition to coliform and nitrifying bacteria, and bioreactor studies to evaluate impact on operating parameters...
September 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28854890/chemoradiotherapy-versus-surgery-followed-by-postoperative-radiotherapy-in-tonsil-cancer-korean-radiation-oncology-group-krog-study
#20
Sanghyuk Song, Hong-Gyun Wu, Chang Geol Lee, Ki Chang Keum, Mi Sun Kim, Yong Chan Ahn, Dongryul Oh, Hyo Jung Park, Sang-Wook Lee, Geumju Park, Sung Ho Moon, Kwan Ho Cho, Yeon-Sil Kim, Yongkyun Won, Young-Taek Oh, Won-Taek Kim, Jae-Uk Jeong
BACKGROUND: Treatment of tonsil cancer, a subset of oropahryngeal cancer, varies between surgery and radiotherapy. Well-designed studies in tonsil cancer have been rare and it is still controversial which treatment is optimal. This study aimed to assess the outcome and failure patterns in tonsil cancer patients treated with either approaches. METHODS: We retrospectively reviewed medical records of 586 patients with tonsil cancer, treated between 1998 and 2010 at 16 hospitals in Korea...
August 30, 2017: BMC Cancer
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