keyword
https://read.qxmd.com/read/38167210/dreaming-during-gastrointestinal-endoscopy-under-propofol-ciprofol-or-remimazolam-anesthesia-study-protocol-for-a-parallel-design-double-blind-single-center-trial
#21
JOURNAL ARTICLE
Le-Qiang Xia, Rui Zhou, Rui Deng, Dan Zhou, Jia Han, Zhi-Fu Zhao, San-Jie Gao, Xian-Jie Zhang, Yu-Kai Zhou, Li-Ze Xiong
BACKGROUND: Dreaming sometimes occurs during sedation. It has been reported that factors such as different anesthetics, depth of anesthesia, age, sex, and preoperative psychological state may affect dreams. Ciprofol and remimazolam are novel choices for painless endoscopy. Herein, we aimed to investigate dreaming during gastrointestinal endoscopy under propofol, ciprofol, and remimazolam anesthesia respectively. METHODS: This is a prospective, parallel-design double-blind, single-center clinical trial...
January 2, 2024: Trials
https://read.qxmd.com/read/38158910/-anxiety-in-subjects-with-cardiovascular-disease-current-diagnostic-strategies-and-therapeutic-options-a-review
#22
JOURNAL ARTICLE
V N Shishkova
Anxiety and anxiety disorders are important modifiable risk factors for cardiovascular and other common chronic non-communicable diseases and complications. Anxiety disorders significantly reduce the motivation and adherence of patients to lifestyle changes and drug therapy, significantly worsen the quality of life, and increase the risk of disability and the costs of the health care system. The issues of diagnosis and therapy of anxiety are relevant for the practice of physicians and cardiologists due to the high incidence of anxiety disorders in patients with cardiovascular diseases, a decrease in the quality of life and an increase in adverse outcomes, and also due to the insufficient awareness of the risks associated with the psycho-emotional state of patients...
October 11, 2023: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/38150433/influencing-factors-of-falls-among-older-adults-in-chinese-retirement-institutions-a-systematic-review-and-meta-analysis
#23
JOURNAL ARTICLE
Xiaoxing Huang, Yunlan Jiang, Yaxin Liu, Liyin Shen, Jing Pan, Yue Zhang
BACKGROUND: The incidence of falling has always been high among the elderly, and it was easy to cause injuries to the elderly and seriously affect their quality of life. There were many studies have been conducted on risk factors affecting the fall of the elderly, but the results widely, retirement institutions as a gathering place for the elderly, there was currently no comprehensive analysis of the factors related to elderly falls in pension institutions. This study aimed to explore the influencing factors of falls among older adults in Chinese nursing homes...
2023: PloS One
https://read.qxmd.com/read/38127679/hemodynamic-instability-after-axillary-artery-rupture-following-inferior-glenohumeral-joint-dislocation-a-case-report
#24
JOURNAL ARTICLE
Alexander Bech Rasmussen, Rikke Thorninger, Daniel Wæver
BACKGROUND Inferior shoulder dislocation is a rare type of glenohumeral joint dislocation. A serious complication to shoulder dislocation is axillary artery injury, which should be taken into consideration early to avoid potentially permanent damage. Literature on artery injury following inferior shoulder dislocation is sparse. CASE REPORT We report the case of a 71-year-old man with a traumatic inferior shoulder dislocation due to a fall. The patient had a medical history of stroke, and thus had a daily intake of 10 mg Warfarin...
December 21, 2023: American Journal of Case Reports
https://read.qxmd.com/read/38089126/an-interesting-observation-prolonged-green-urine-can-be-a-combined-effect-of-decreased-liver-and-renal-function-in-a-patient-with-heart-failure-a-case-report
#25
Tuğçe Çöllüoğlu, Melahat Hicran Aksu, Orhan Önalan, Yeşim Akın
BACKGROUND: The administration of propofol and methylene blue (MB) can be associated with the appearance of prolonged green urine discoloration, particularly in patients with heart failure (HF) concomitant with renal and liver dysfunction. Understanding the reasons behind this phenomenon is of clinical significance. CASE SUMMARY: A 79-year-old woman with a history of HF experienced dyspnoea and persistent green urine discoloration for a week, leading to her hospitalization for acutely decompensated HF...
December 2023: European Heart Journal. Case Reports
https://read.qxmd.com/read/38087684/measuring-the-intensive-care-experience-of-intensive-care-unit-patients-a-cross-sectional-study-in-western-china
#26
JOURNAL ARTICLE
Aiping Hu, Jia Wang, Qimin Zhou, Lijia Xu, Shuang Yang, Mingfang Xiang, Guorong Wang
BACKGROUND: The negative experiences of intensive care unit (ICU) patients seriously affect their quality of life and survival outcomes. Thus, it is of great significance to evaluate the monitoring experience of ICU patients for the clinical improvement of their experiences and promote interventions. OBJECTIVES: The objective of this study was to investigate patients' experiences of ICU and to understand the sources of patient experience and influencing factors...
December 11, 2023: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://read.qxmd.com/read/38070188/promethazine-induced-thrombophlebitis-in-a-nigerian-man-a-case-report
#27
Chinedu Michael Dike, Philip Chinedu Ndubuisi Okere
INTRODUCTION: Promethazine is a phenothiazine derivative that possesses antihistamine, anti-dopaminergic and anticholinergic properties. It is commonly used to treat motion sickness, allergic conditions, nausea and vomiting, in addition to its use as a sedative. Promethazine has vesicant properties and is highly caustic to the intima of blood vessels and surrounding tissues. Intravenous administration may result in thrombophlebitis, unintentional intra-arterial administration, perivascular extravasation and tissue necrosis...
December 4, 2023: West African Journal of Medicine
https://read.qxmd.com/read/38068360/remimazolam-pilot-for-office-based-dental-sedation-adverse-events-awareness-and-outcomes
#28
JOURNAL ARTICLE
Rudi Swart, Sabine S A Maes, David Cavanaugh, Keira P Mason
In recent years, remimazolam has gained approval for use in adult procedural sedation in both the United Kingdom and the United States, potentially offering an alternative to conventional sedatives like propofol and midazolam for procedural sedation. However, there is a limited body of literature that systematically reviews the outcomes of a remimazolam-alfentanil combination protocol for routine office-based dental procedures. The primary objective of this pilot study was to assess the occurrence of significant adverse events associated with the use of a remimazolam-alfentanil sedation protocol for adult dental procedures...
November 25, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38054233/drug-interactions-in-neurosurgical-patients
#29
JOURNAL ARTICLE
A I Baranich, A A Sychev, I A Savin, V G Kudrina
We analyzed literature data on the most common drug interactions in neurosurgical patients. Drug interactions are a potential cause of adverse and dangerous clinical events and outcomes. Awareness of nature of drug interactions is valuable to avoid negative consequences when using combination of several drugs. Polypharmacy in neurosurgical patients is caused by treatment of intracranial lesions (hormonal therapy, antiepileptic drugs, etc.) and concomitant somatic diseases that increases the risk of drug interactions...
2023: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://read.qxmd.com/read/38009426/influence-of-ketamine-propofol-or-isoflurane-on-intraocular-pressure-heart-rate-and-blood-pressure-in-healthy-dogs-premedicated-with-medetomidine-and-midazolam
#30
JOURNAL ARTICLE
Masoud Khaleghi, Ali Asghar Sarchahi, Hossein Kazemi Mehrjerdi, Mehdi Rasekh, Dariush Saadati
BACKGROUND: According to the findings of several studies, sedatives and anaesthetics have different effects on the functioning of the cardiovascular system and intraocular pressure (IOP). For accurate diagnosis, treatment and surgery with minimal complications, it is necessary to be aware of the effects of sedatives and anaesthetics on the cardiovascular system and IOP. OBJECTIVES: The aim of this study was to evaluate the effects of sedatives (medetomidine and midazolam) and anaesthetics (ketamine, propofol and isoflurane) on IOP, heart rate (HR) and blood pressure in dogs...
November 27, 2023: Veterinary Medicine and Science
https://read.qxmd.com/read/38001507/awareness-with-paralysis-and-symptoms-of-post-traumatic-stress-disorder-among-mechanically-ventilated-emergency-department-survivors-ed-awareness-2-trial-study-protocol-for-a-pragmatic-multicenter-stepped-wedge-cluster-randomized-trial
#31
JOURNAL ARTICLE
Brian M Fuller, Brian E Driver, Michael B Roberts, Christa A Schorr, Kathryn Thompson, Brett Faine, Julianne Yeary, Nicholas M Mohr, Ryan D Pappal, Robert J Stephens, Yan Yan, Nicholas J Johnson, Brian W Roberts
BACKGROUND: Awareness with paralysis (AWP) is memory recall during neuromuscular blockade (NMB) and can cause significant psychological harm. Decades of effort and rigorous trials have been conducted to prevent AWP in the operating room, where prevalence is 0.1-0.2%. By contrast, AWP in mechanically ventilated emergency department (ED) patients is common, with estimated prevalence of 3.3-7.4% among survivors given NMB. Longer-acting NMB use is a critical risk for AWP, and we have shown an association between ED rocuronium use and increased AWP prevalence...
November 25, 2023: Trials
https://read.qxmd.com/read/38000322/costing-analysis-of-a-point-of-care-drug-checking-program-in-rhode-island
#32
JOURNAL ARTICLE
Javier A Cepeda, Erin Thompson, Merci Ujeneza, Jessica Tardif, Thomas Walsh, Alexis Morales, Joseph G Rosen, Traci C Green, Ju Nyeong Park
BACKGROUND: Drug checking is a harm reduction strategy that provides greater awareness and information about the drug supply to the community. While fentanyl test strips are low-cost and available in most parts of the U.S., community-based organizations are considering using more sophisticated technologies, such as Fourier-transform infrared (FTIR) spectroscopy to test drugs. FTIR can detect multiple substances in a non-destructive manner that can be rapidly communicated to the program client by a trained technician, however implementation costs in community-based settings have not been assessed...
November 15, 2023: Drug and Alcohol Dependence
https://read.qxmd.com/read/37997530/early-processed-electroencephalography-for-the-monitoring-of-deeply-sedated-mechanically-ventilated-critically-ill-patients
#33
JOURNAL ARTICLE
Eva Favre, Adriano Bernini, John-Paul Miroz, Samia Abed-Maillard, Anne-Sylvie Ramelet, Mauro Oddo
BACKGROUND: Deep sedation may be indicated in the intensive care unit (ICU) for the management of acute organ failure, but leads to sedative-induced delirium. Whether processed electroencephalography (p-EEG) is useful in this setting is unclear. METHODS: We conducted a single-centre observational study of non-neurological ICU patients sedated according to a standardized guideline of deep sedation (Richmond Agitation Sedation Scale [RASS] between -5 and -4) during the acute phase of respiratory and/or cardio-circulatory failure...
November 23, 2023: Nursing in Critical Care
https://read.qxmd.com/read/37985256/-restraint-in-geriatrics-france-s-backwardness
#34
JOURNAL ARTICLE
Jean-Pierre Jacus, Marie-Christine Brunet-Jarrige, Christine-Vanessa Cuervo-Lombard
In the absence of legal provisions, passive physical restraint methods in geriatrics were defined at the start of this century, accompanied by recommendations relating to their use. Despite the frequency of these measures of restraint, there are few French publications on this subject. It seems that this practice varies according to the geriatric establishments and prevails in hospital more than in nursing home. The most widespread method is the dual barrier on the bed, as well as in hospital than in nursing home...
November 18, 2023: L'Encéphale
https://read.qxmd.com/read/37953454/awake-surgery-for-lesional-epilepsy-in-resource-limited-settings-case-report-and-review-of-literature
#35
Mohammad Hamza Bajwa, Syeda Amrah Hashmi, Abdullah Nisar, Muhammad Waqas Baqai, Saqib Kamran Bakhshi, Muskaan Abdul Qadir, Faraz Shafiq, Syed Ather Enam
Epilepsy surgery is a well-established treatment for drug-resistant epilepsy, with awake craniotomy being used in certain cases to remove epileptogenic foci while preserving crucial brain functions. We are presenting the first reported case from Pakistan of a 19-year-old woman who underwent awake epilepsy surgery to treat cortical dysplasia. She had a history of generalized tonic-clonic seizures since her childhood and was referred to our clinic due to an increase in seizure frequency. EEG and MRI identified the epileptogenic focus in the right parieto-temporal region...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37948204/the-association-between-glasgow-coma-scale-scores-and-ptsd-in-military-trauma-casualties-does-mental-status-following-injury-play-a-role-in-ptsd-development
#36
JOURNAL ARTICLE
Shir Bulis, Tomer Talmy, Irina Radomislensky, Daniel Gelman, Shir Bushinsky, Dikla Nachum, Gaia Tomer, Avishai M Tsur, Omer Paulman, Sami Gendler, Ofer Almog, Avi Benov
BACKGROUND: Posttraumatic stress disorder (PTSD) is prevalent among military personnel and may arise following a wide range of traumatic exposures. Consciousness level following traumatic injury may play a role in the development of PTSD, but its effects have been primarily investigated in the context of traumatic brain injury. METHODS: Registry-based study surveying three databases documenting care from point of injury to long-term rehabilitation of traumatic injuries among military personnel...
November 8, 2023: Military Medicine
https://read.qxmd.com/read/37926072/the-clearance-of-midazolam-and-metabolites-during-continuous-renal-replacement-therapy-in-critically-ill-patients-with-covid-19
#37
JOURNAL ARTICLE
Tim J L Smeets, Hilde R H de Geus, Abraham J Valkenburg, Lauren Baidjoe, Diederik A M P J Gommers, Birgit C P Koch, Nicole G M Hunfeld, Henrik Endeman
INTRODUCTION: Midazolam-based continuous intravenous sedation in patients admitted to the intensive care unit (ICU) was a necessity during the COVID-19 pandemic. However, benzodiazepine-based sedation is associated with a high incidence of benzodiazepine-related delirium and additional days on mechanical ventilation. Due to the requirement of high midazolam doses in combination with the impaired renal clearance (CL) of the pharmacological active metabolite 1-OH-midazolam-glucuronide (10% compared to midazolam), ICU patients with COVID-19 and continuous renal replacement therapy (CRRT) were at risk of unintended prolonged sedation...
November 3, 2023: Blood Purification
https://read.qxmd.com/read/37926053/is-the-patient-state-index-a-reliable-parameter-as-guide-to-anaesthesiology-in-cranial-neurosurgery-a-first-intraoperative-study-and-a-literature-review
#38
JOURNAL ARTICLE
Riccardo Carrai, Cristiana Martinelli, Fabrizio Baldanzi, Simonetta Gabbanini, Camilla Bonaudo, Agnese Pedone, Capelli Federico, Riccardo Caramelli, Maddalena Spalletti, Francesco Lolli, Antonello Grippo, Luca Bucciardini, Alessandro Della Puppa, Tommaso Agostino Ninone, Andrea Amadori
BACKGROUND: Patient State Index (PSI) and Suppression Ratio (SR) are two indices calculated by quantitative analysis of EEG used to estimate the depth of anaesthesia but their validation in neurosurgery must be done. Our aim was to investigate the congruity PSI and SR with raw EEG monitoring in neurosurgery. METHODS: We included 34 patients undergoing elective cranial neurosurgery. Each patient was monitored by a SedLine device (PSI and SR) and by raw EEG. To appraise the agreement between PSI, SR and EEG Suppr%, Bland-Altman analysis was used...
October 2023: Clinical Neurophysiology
https://read.qxmd.com/read/37925355/surgical-sensation-during-caesarean-section-a-qualitative-analysis
#39
JOURNAL ARTICLE
A Jiang, T Perry, K Walker, A Burfoot, L Patterson
BACKGROUND: Caesarean section (CS) is a major abdominal surgery performed usually on a young and healthy population under neuraxial anesthesia with little to no sedation. This creates a distinct surgical experience whereby patients are aware of the surgical process, physical sensations, and their environment. This study aimed to provide an in-depth descriptive assessment of subjective surgical experience during CS under regional anaesthesia. We expected the information gained would enhance our current understanding and better alleviate patient anxiety through informed counselling...
November 2, 2023: International Journal of Obstetric Anesthesia
https://read.qxmd.com/read/37914581/evaluation-of-putative-signatures-of-consciousness-using-specific-definitions-of-responsiveness-connectedness-and-consciousness
#40
JOURNAL ARTICLE
Cameron P Casey, Sean Tanabe, Zahra Z Farahbakhsh, Margaret Parker, Amber Bo, Marissa White, Tyler Ballweg, Andrew Mcintosh, William Filbey, Matthew I Banks, Yuri B Saalmann, Robert A Pearce, Robert D Sanders
BACKGROUND: Understanding the neural correlates of consciousness has important ramifications for the theoretical understanding of consciousness and for clinical anaesthesia. A major limitation of prior studies is the use of responsiveness as an index of consciousness. We identified a collection of measures derived from unresponsive subjects and more specifically their association with consciousness (any subjective experience) or connectedness (specific experience of environmental stimuli)...
October 30, 2023: British Journal of Anaesthesia
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