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Sedation awareness

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https://www.readbyqxmd.com/read/29696175/global-perspective-on-colonoscopy-use-for-colorectal-cancer-screening-a-multi-country-survey-of-practicing-colonoscopists
#1
Céline Audibert, Anna Perlaky, Daniel Glass
Objectives: To examine colorectal cancer screening practices among colonoscopy specialists from 5 countries and inform public health needs in improvement of the ongoing global crisis in colorectal cancer. Methods: An online survey among colonoscopy specialists was conducted in France, Germany, the United Kingdom, Japan, and the United States. The survey covered topics on colonoscopy practices in the screening as well as in the treatment setting, as well as expected trends...
September 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29669562/comfort-in-palliative-sedation-compas-a-transdisciplinary-mixed-method-study-protocol-for-linking-objective-assessments-to-subjective-experiences
#2
Stefaan Six, Steven Laureys, Jan Poelaert, Johan Bilsen, Peter Theuns, Reginald Deschepper
BACKGROUND: In case of untreatable suffering at the end of life, palliative sedation may be chosen to assure comfort by reducing the patient's level of consciousness. An important question here is whether such sedated patients are completely free of pain. Because these patients cannot communicate anymore, caregivers have to rely on observation to assess the patient's comfort. Recently however, more sophisticated techniques from the neurosciences have shown that sometimes consciousness and pain are undetectable with these traditional behavioral methods...
April 18, 2018: BMC Palliative Care
https://www.readbyqxmd.com/read/29668190/bedsharing-at-home-breastfeeding-and-sudden-infant-death-recommendations-for-health-professionals
#3
Alejandro Jenik, Roxana Conti
The Sudden and Unexpected Infant Death Task Force together with the Subcommittee on Breastfeeding of the Sociedad Argentina de Pediatría have issued updated recommendations on bedsharing with the parents, a practice which remains controversial. Sleeping with the mother maximizes breastfeeding, which is protective against Sudden Infant Death. There is a small group of infants that have been associated with an increased risk of Sudden Infant Death and fatal sleeping accidents in certain circumstances. These hazards include parental smoking, sedating drugs or medication and alcohol consumption prior to sleep and sofa sharing situations...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29643163/effect-of-intratracheal-dexmedetomidine-administration-on-recovery-from-general-anaesthesia-after-gynaecological-laparoscopic-surgery-a-randomised-double-blinded-study
#4
Fei Wang, Haoxiang Zhong, Xiaoyan Xie, Weiping Sha, Caili Li, Zhenping Li, Zhuomei Huang, Chaojin Chen
OBJECTIVES: To examine the efficacy of intratracheal dexmedetomidine (Dex) injection for the prevention of the laryngeal response on emergence from general anaesthesia following gynaecological laparoscopic surgery. DESIGN: Prospective, randomised, double-blinded, controlled trial. SETTING: A general hospital, Guangdong Province, China. PARTICIPANTS: All patients who underwent elective laparoscopic gynaecological surgery, aged 18-60 years old, 40-80 kg in weight, American Society of Anesthesiologists class I-II were eligible...
April 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29622502/chronic-pain-medication-management-of-older-populations-key-points-from-a-national-conference-and-innovative-opportunities-for-pharmacy-practice
#5
Julia Fiona-Maree Gilmartin-Thomas, J Simon Bell, Danny Liew, Carolyn A Arnold, Rachelle Buchbinder, Colin Chapman, Flavia Cicuttini, Malcolm Dobbin, Stephen J Gibson, Melita J Giummarra, Jenny Gowan, Benny Katz, Dan I Lubman, Matthew McCrone, Jennifer Pilgrim, Anneliese Synnot, Eleanor van Dyk, Barbara Workman, John McNeil
OBJECTIVE: Inappropriate use of pain medication has serious consequences for older populations. Experts in the field have noted an increase in opioid prescriptions, and opioid-related hospitalisations and deaths among this vulnerable population. In the pursuit of educating pharmacists, physicians, allied healthcare professionals, researchers, academics and the public facing the challenges of chronic pain medication management, 'The Inaugural Monash University School of Public Health and Preventive Medicine (SPHPM) Best Practice in Chronic Pain Medication Management Day Conference' was held in December 2016 at the Alfred Medical Research and Education Precinct (Melbourne, Australia)...
March 19, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29622310/the-failed-sedation-solutions-for-the-oral-and-maxillofacial-surgeon
#6
REVIEW
Robert C Bosack
Due to wide variation in patient responses, both intended and adverse, it is impossible to successfully sedate all patients. Choosing the right drug and dose regimen can be challenging, especially in patients who are naïve to anesthesia. Underdosing can lead to pain perception, patient movement and combativeness, awareness with recall, and the sympathetic neuroendocrine stress response. Overdosing can lead to unintended loss of upper airway tone, hypoventilation/apnea, adverse cardiovascular changes, and prolonged sedation (with its attendant problems)...
May 2018: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/29618173/sedation-in-pediatric-esophagogastroduodenoscopy
#7
REVIEW
Seak Hee Oh
Pediatric esophagogastroduodenoscopy (EGD) has become an established diagnostic and therapeutic modality in pediatric gastroenterology. Effective sedation strategies have been adopted to improve patient tolerance during pediatric EGD. For children, safety is a fundamental consideration during this procedure as they are at a higher risk of severe adverse events from procedural sedation compared to adults. Therefore, a detailed risk evaluation is required prior to the procedure, and practitioners should be aware of the benefits and risks associated with sedation regimens during pediatric EGD...
March 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/29605866/effects-of-gadolinium-based-contrast-agents-on-submandibular-gland-tissue-in-rats
#8
Fatma Beyazal Celiker, Levent Tumkaya, Adnan Yilmaz, Zerrin Ozergin Coskun, Metin Celiker, Fatih Oghan, Tolga Mercantepe, Suat Terzi, Engin Dursun
AIM: The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on submandibular gland tissue (SGT) of the rats. MATERIAL AND METHOD: Twenty-four Sprague Dawley female rats were included the study. Group 1 was determined as a control group (n = 6). Group 2 was determined as saline group (n = 6). Group 3 was determined as Omniscan group (n = 6) and received only intraperitoneal (IP) 0...
March 31, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29580965/designing-a-nurse-delivered-delirium-bundle-what-intensive-care-unit-staff-survivors-and-their-families-think
#9
Leona Bannon, Jennifer McGaughey, Mike Clarke, Daniel F McAuley, Bronagh Blackwood
BACKGROUND: Implementation of quality improvement interventions can be enhanced by exploring the perspectives of those who will deliver and receive them. We designed a non-pharmacological bundle for delirium management for a feasibility trial, and we sought to obtain the views of intensive care unit (ICU) staff, survivors, and families on the barriers and facilitators to its implementation. OBJECTIVE: The objective of this study is to determine the barriers and facilitators to a multicomponent bundle for delirium management in critically ill patients comprising (1) education and family participation, (2) sedation minimisation and pain, agitation, and delirium protocol, (3) early mobilisation, and (4) environmental interventions for sleep, orientation, communication, and cognitive stimulation...
May 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29578199/initial-treatment-dropout-in-patients-with-substance-use-disorders-attending-a-tertiary-care-de-addiction-centre-in-north-india
#10
Debasish Basu, Abhishek Ghosh, Siddharth Sarkar, Bichitra Nanda Patra, B N Subodh, Surendra Kumar Mattoo
Background & objectives: Dropout from substance use disorders treatment is associated with poor outcomes. Although many factors have been associated with an early dropout of patients, the reasons for dropping out of treatment prematurely remain poorly understood particularly in the Indian context. This study was aimed to study socio-demographic and clinical variables predicting initial dropout of patients attending a tertiary care de-addiction treatment centre in north India. Methods: Information was extracted from the records of consecutive newly registered patients from January 2011 to December 2014...
November 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29556753/the-use-of-drug-induced-sleep-endoscopy-in-england-and-belgium
#11
Vik Veer, Henry Zhang, Jolien Beyers, Olivier Vanderveken, Bhik Kotecha
PURPOSE: The purpose of this international survey is to ascertain the current practice of drug-induced sleep endoscopy (DISE) for patients with sleep-disordered breathing (SDB) by Otolaryngologists in the United Kingdom and Belgium. We compare the results with recommendations from the European Position Paper on drug-induced sleep endoscopy. METHODS: An online questionnaire was circulated to Consultant Otolaryngologists, independent practitioners, and trainees across the two countries...
March 19, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29537305/practical-implications-of-motion-correction-with-motion-insensitive-radial-k-space-acquisitions-in-mri
#12
Mustafa M Almuqbel, Gareth Leeper, Ross Keenan, David N Plamer, Tracy R Melzer
OBJECTIVES: To highlight specific instances when radial k-space acquisitions in magnetic resonance imaging result in image artifacts and how to ameliorate such artifacts. METHODS: We acquired axial T2  weighted MR images on (1) the American College of Radiology (ACR) phantom and (2) a sedated sheep with rectilinear and multi-blade radial k-space filling acquisitions. Images were acquired on four (2 × 1.5T and 2 × 3T) different MRI scanners. For the radial k-space acquisitions, we acquired images with and without motion correction...
March 14, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29524200/prevalence-of-discordant-elevations-of-state-entropy-and-bispectral-index-in-patients-at-amnestic-sevoflurane-concentrations-a-historical-cohort-study
#13
Richard H Epstein, Joni M Maga, Michael E Mahla, Eric S Schwenk, Marc J Bloom
BACKGROUND: Processed electroencephalogram (EEG) monitors help assess the hypnotic state during general anesthesia or sedation. Maintaining the bispectral index (BIS) or state entropy (SE) between 40 and 60 has been recommended to mitigate anesthesia awareness. Nonetheless, SEs > 70 were frequently observed at end-tidal sevoflurane concentrations unlikely to allow awareness. We sought to determine the prevalence of elevated discordant measurements during BIS and SE monitoring. METHODS: Electronic data collected over 11 months at two academic hospitals were retrospectively reviewed...
May 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29477264/patient-knowledge-regarding-colorectal-cancer-risk-opinion-of-screening-and-preferences-for-a-screening-test
#14
Courtney C Moreno, Thomas Jarrett, Brianna L Vey, Pardeep K Mittal, Elizabeth A Krupinski, David L Roberts
AIMS: To assess patient knowledge about colorectal cancer incidence and prognosis as well as willingness to undergo screening with various tests (eg, optical colonoscopy, stool-based tests, computed tomographic colonography (CTC)). MATERIALS AND METHODS: A survey was administered to consecutive patients of a general academic-based internal medicine clinic. RESULTS: Survey response rate was 86.3%. A majority of respondents (55%) reported being aware of general information about colorectal cancer, and 99% indicated a belief that colorectal cancer screening was a good idea...
January 6, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29426260/gambling-and-its-clinical-correlates-in-university-students
#15
Jon E Grant, Katherine Lust, Gary A Christenson, Sarah A Redden, Samuel R Chamberlain
OBJECTIVE: This study sought to examine the prevalence of gambling disorder (GD) in a university sample and its associated physical and mental health correlates. METHODS: A 156-item anonymous online survey was distributed via random email generation to a sample of 9449 university students. Current use of alcohol and drugs, psychological and physical status and academic performance were assessed, along with questionnaire-based measures of impulsivity and compulsivity...
February 9, 2018: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29423659/venous-thromboembolism-during-treatment-with-antipsychotics-a-review-of-current-evidence
#16
REVIEW
Anna K Jönsson, Johan Schill, Hans Olsson, Olav Spigset, Staffan Hägg
This article summarises the current evidence on the risk of venous thromboembolism (VTE) with the use of antipsychotics. An increasing number of observational studies indicate an elevated risk of VTE in antipsychotic drug users. Although the use of certain antipsychotics has been associated with VTE, current data can neither conclusively verify differences in occurrence rates of VTE between first- and second-generation antipsychotics or between individual compounds, nor identify which antipsychotic drugs have the lowest risk of VTE...
January 2018: CNS Drugs
https://www.readbyqxmd.com/read/29407363/society-of-family-planning-clinical-guidelines-pain-control-in-surgical-abortion-part-1-local-anesthesia-and-minimal-sedation
#17
REVIEW
Rebecca H Allen, Rameet Singh
Satisfactory pain control for women undergoing surgical abortion is important for patient comfort and satisfaction. Clinicians ought to be aware of the safety and efficacy of different pain control regimens. This document will focus on nonpharmacologic modalities to reduce pain and pharmacologic interventions up to the level of minimal sedation. For surgical abortion without intravenous medications, a multimodal approach to pain control may combine a dedicated emotional-support person, visual or auditory distraction, administration of local anesthesia to the cervix with buffered lidocaine and a preoperative nonsteroidal anti-inflammatory drug...
January 31, 2018: Contraception
https://www.readbyqxmd.com/read/29381909/metoprolol-treatment-of-dual-cocaine-and-bupropion-cardiovascular-and-central-nervous-system-toxicity
#18
John R Richards, Jessica B Gould, Erik G Laurin, Timothy E Albertson
Cardiovascular and central nervous system (CNS) toxicity, including tachydysrhythmia, agitation, and seizures, may arise from cocaine or bupropion use. We report acute toxicity from the concomitant use of cocaine and bupropion in a 25-year-old female. She arrived agitated and uncooperative, with a history of possible antecedent cocaine use. Her electrocardiogram demonstrated tachycardia at 130 beats/min, with a corrected QT interval of 579 ms. Two doses of 5 mg intravenous metoprolol were administered, which resolved the agitation, tachydysrhythmia, and corrected QT interval prolongation...
January 31, 2018: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29372938/second-generation-antipsychotic-induced-hypoglycemia
#19
Tomonari Fujita, Yoshito Mizoguchi, Yutaka Kunitake, Hiroshi Tateishi, Takayoshi Inaba, Takahiro A Kato, Akira Monji
Complaints of hypoglycemia resemble the sedative effect of antipsychotics. As such, clinicians may overlook hypoglycemia in patients with psychiatric disorders. Here, a case of hypoglycemia associated with hyperinsulinemia induced by quetiapine in a female patient with bipolar disorder is reported. The case suggests that clinicians should be aware of the potential for hypoglycemia induced by second-generation antipsychotics.
January 25, 2018: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29349346/characteristics-of-electroencephalogram-signatures-in-sedated-patients-induced-by-various-anesthetic-agents
#20
REVIEW
Byung-Moon Choi
Devices that monitor the depth of hypnosis based on the electroencephalogram (EEG) have long been commercialized, and clinicians use these to titrate the dosage of hypnotic agents. However, these have not yet been accepted as standard monitoring devices for anesthesiology. The primary reason is that the use of these monitoring devices does not completely prevent awareness during surgery, and the development of these devices has not taken into account the neurophysiological mechanisms of hypnotic agents, thus making it possible to show different levels of unconsciousness in the same brain status...
December 2017: Journal of Dental Anesthesia and Pain Medicine
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