Desmond M Connolly, Leigh A Madden, Victoria C Edwards, Timothy J D'Oyly, Stephen D R Harridge, Thomas G Smith, Vivienne M Lee
INTRODUCTION: Consistent blood biomarkers of hypobaric (altitude) decompression stress remain elusive. Recent laboratory investigation of decompression sickness risk at 25,000 ft (7620 m) enabled evaluation of early pathophysiological responses to exertional decompression stress. METHODS: In this study, 15 healthy men, aged 20-50 yr, undertook 2 consecutive (same-day) ascents to 25,000 ft (7620 m) for 60 and 90 min, breathing 100% oxygen, each following 1 h of prior denitrogenation...
October 1, 2023: Aerospace Medicine and Human Performance